3K skills · sorted by relevance
Design and improve in-app screens that invite users to paid plans. Develop complete screen copy, prompt timing rules, upgrade flows, and experiment ideas based on the value users have already experienced.
Resume interrupted work by reviewing recent Screenpipe activity and checking the current state of relevant files, jobs, or services. Recover the last verified result, identify unfinished steps, and avoid repeating actions that may already have completed.
Prepare a short brief for an upcoming meeting by confirming the event and participants, reviewing relevant Screenpipe history, and summarizing prior commitments, unresolved decisions, likely purpose, and two useful questions with supporting links.
Add or modify Tauri commands in the screenpipe desktop app and regenerate TypeScript bindings, the code connecting frontend calls to Rust handlers. Follow the required annotations and checks to keep both sides consistent.
Create and refine screen designs in Stitch from text descriptions or images. The skill clarifies layout requirements, edits existing screens, explores alternative designs, and saves HTML and screenshots for review.
Capture product screenshots for landing pages, newsletters, social posts, and presentations by operating the real app. Check page structure, image pixels, and visual appearance, then retake images with overlapping text, clipping, or other visible defects.
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2/PE3/PE3b/PEmax variants, MOSAIC in situ saturation mutagenesis, the PRIME pooled-screen methodology (Ren 2023; ~3,699 ClinVar variant screens), chromatin context as a major locus-level determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
The English summary is being prepared. Showing the original description.
Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
The English summary is being prepared. Showing the original description.
Connect user journeys to screens, defining the UI structure and navigation paths during PRD v0.4 User Journeys. Triggers on requests to define screens, design screen flows, map UI structure, plan navigation, or when user asks "what screens do we need?", "define screens", "screen flow", "UI structure", "information architecture", "navigation design", "wireframe planning". Consumes UJ- (User Journey Mapping), FEA- (Feature Value Planning), BR- (constraints). Outputs SCR- entries for screens and DES- entries for design system elements. Feeds v0.5 Red Team Review.
The English summary is being prepared. Showing the original description.
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2/PE3/PE3b/PEmax variants, MOSAIC in situ saturation mutagenesis, the PRIME pooled-screen methodology (Ren 2023; ~3,699 ClinVar variant screens), chromatin context as a major locus-level determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
The English summary is being prepared. Showing the original description.
Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
The English summary is being prepared. Showing the original description.
Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
The English summary is being prepared. Showing the original description.
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
The English summary is being prepared. Showing the original description.
Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
The English summary is being prepared. Showing the original description.
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
The English summary is being prepared. Showing the original description.
Build a single mobile app screen mockup in an iPhone 15 Pro frame. Choose from six layout types, apply the project's design settings, and produce HTML with device details such as the Dynamic Island and status icons.
Generate marketing screenshots with Playwright, a browser automation tool. Use the images for landing-page hero sections, App Store listings, or changelog visuals. The catalogue entry points to an upstream bundle containing the full workflow and supporting resources.
Generate mobile app screen concepts and connected screen flows for iOS, Android, or cross-platform products. The skill emphasizes readable text, consistent colors and navigation, and clean phone mockups. It produces images rather than implementation code.
Design and improve in-app screens that invite users to pay or upgrade. Plan messages, timing, feature previews, and payment steps for usage limits, locked features, and trial endings, with clear options to dismiss or continue free.
Analyze a chosen period of Screenpipe work history to find repeated research tasks, match them with existing skills, and prepare new skill drafts or combinations of existing skills for review.
Find stock investment candidates by combining financial filters with research into investment themes. Produce five to ten long or short ideas, each with a rationale and risks, plus a comparison table and priorities for further research.
Capture desktop screenshots on macOS, Linux, and Windows. Save the full screen, a selected window, or a region defined by coordinates, with support for a specified file path, the default location, or temporary storage.
Build or update Figma screens from code or descriptions using an existing design system, a shared set of components and visual rules. Assemble sections with reusable components, colors, spacing, and styles, then check their appearance.
Prepare screenpipe component releases by updating versions and dependency lock files, running required build checks, and triggering GitHub Actions. Verify build results and release artifacts, then hand public app publication over to a person.