683 skills · sorted by relevance
Build and verify Comparison table for Commerce and checkout with Bootstrap v5.3 using a working semantic implementation, responsive RTL/LTR behavior, theme tokens, test plan and design verification.
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Build and verify Comparison table for Documentation and knowledge with Bootstrap v5.3 using a working semantic implementation, responsive RTL/LTR behavior, theme tokens, test plan and design verification.
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Build and verify Comparison table for Mobile-first interface with Bootstrap v5.3 using a working semantic implementation, responsive RTL/LTR behavior, theme tokens, test plan and design verification.
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Build and verify Comparison table for Marketing landing with Bootstrap v5.3 using a working semantic implementation, responsive RTL/LTR behavior, theme tokens, test plan and design verification.
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Use when working with Allure Testops — allure TestOps test management and analytics platform monitoring. Covers project dashboards, launch tracking, test case management, defect clustering, environment matrix analysis, and CI/CD integration review. Use when managing test cases in Allure TestOps, reviewing launch results, analyzing flaky tests, or tracking quality trends.
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GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.
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LLM Agent engineering: pattern selection (12-mode matrix), data simulation, convergence iteration. Covers intent routing, function calling, ReAct, MCP, prompt chaining, guardrails, evaluation.
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bu skill outlines methodologies for performing authorized penetration testing against AWS, Azure, and GCP cloud environments. It covers understanding the shared responsibility model for testing scope, leveraging cloud-specific attack tools like Pacu and ScoutSuite, exploiting IAM misconfigurations, testing for SSRF to cloud metadata services, and reporting Bul:ings aligned to MITRE ATT&CK Cloud matrix.
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Creates, debugs, and optimizes GitHub Actions workflow YAML files. Recommends current action versions with SHA pinning from a daily-updated index of 120+ actions. Configures matrix builds, dependency caching, reusable workflows, OIDC authentication, secrets management, and runner selection. Reviews existing workflows for outdated actions, security issues, and performance problems. Use when the user asks about GitHub Actions, workflows, CI/CD, .github/workflows, any action by name (actions/checkout, setup-node, setup-python, etc.), or workflow optimization.
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This skill outlines methodologies for performing authorized penetration testing against AWS, Azure, and GCP cloud environments. It covers understanding the shared responsibility model for testing scope, leveraging cloud-specific attack tools like Pacu and ScoutSuite, exploiting IAM misconfigurations, testing for SSRF to cloud metadata services, and reporting findings aligned to MITRE ATT&CK Cloud matrix.
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Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.
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Synthesize scientific evidence into a claim-to-source matrix, distinguish primary evidence from interpretation, assess disagreement and study limitations, and produce a calibrated research summary.
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End-to-end bulk time-course analysis from an expression matrix to temporal gene modules and per-cluster pathway enrichment. Orchestrates temporal DE (limma splines or DESeq2 LRT), Mfuzz/tslearn soft clustering of expression-profile shapes, GAM trajectory fitting, per-cluster GO enrichment against a temporal-gene background, and an OPTIONAL circadian rhythm-detection branch (MetaCycle/CosinorPy) that runs only when the design covers >=2 full cycles with >=6-8 evenly spaced samples per cycle. Use when analyzing a bulk time-series expression experiment from any omics platform and deciding limma-splines vs DESeq2-LRT for temporal DE, soft vs hard clustering, whether the sampling design even licenses rhythm detection, and which background to use for enrichment. Not for single-cell pseudotime (see temporal-genomics/trajectory-modeling for the bulk-vs-pseudotime boundary) or unknown-period discovery (see temporal-genomics/periodicity-detection).
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Programmatic untargeted LC-MS feature extraction in R with the modern xcms 4.x MsExperiment/XcmsExperiment API, taking raw mzML to a feature table via CentWave peak detection, retention-time alignment, peak-density correspondence, gap-filling, CAMERA redundancy collapse, and built-in QC feature filtering. Use when converting centroided LC-MS runs into a features-by-samples matrix and deciding centWave/grouping/alignment parameters. For drift correction and QC/CV filtering execution see metabolomics/normalization-qc; for metabolite identification see metabolomics/metabolite-annotation; for the MS-DIAL GUI alternative with MS2Dec deconvolution see metabolomics/msdial-preprocessing; for downstream statistics see metabolomics/statistical-analysis.
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Designs and validates quantitative targeted metabolomics assays (MRM/SRM on triple-quadrupole, PRM on high-resolution instruments) to report absolute concentrations. Covers the internal-standard strategy (external cal -> global IS -> standard addition -> stable-isotope-labeled IS), weighted calibration judged by back-calculated %RE not R-squared, ion-ratio quantifier/qualifier confirmation, matrix-effect/recovery characterization, and ICH M10 method validation. Use when quantifying a closed panel of known metabolites with units, building or validating an LC-MS/MS assay, choosing an IS or calibration weighting, or judging whether a reported concentration is trustworthy. For untargeted feature detection see metabolomics/xcms-preprocessing; for group statistics see metabolomics/statistical-analysis; for flux/MID/tracing see metabolomics/isotope-tracing.
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Runs the MS-DIAL preprocessing workflow (peak picking, MS2Dec spectral deconvolution, alignment, gap-filling) and imports the alignment-result table into R or Python with honest filtering. Use when preprocessing LC-MS DDA/DIA (SWATH) raw data with MS-DIAL, deciding MS-DIAL vs XCMS, configuring the MsdialConsoleApp console run, or parsing an MS-DIAL export into a clean feature matrix. For programmatic R peak detection and the feature-table-as-artifact framing see metabolomics/xcms-preprocessing; for lipid annotation mode see metabolomics/lipidomics; for MSI-level confidence honesty see metabolomics/metabolite-annotation; for drift correction and QC see metabolomics/normalization-qc.
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Answers "can CARLA do X here, and is there a vetted procedure for it" before you promise anything, and detects client/server/tree version skew — a support matrix over the whole collection (covered by a skill / works but undocumented / present but untested / broken or removed), an index of the features that are verified BROKEN on 0.10.0 (gbuffers crash the server, map layers do nothing, Landmark.waypoint is None, standalone asset packages are gone), and a probe that reports what this machine's build flags and running server actually offer. Use when the user asks whether CARLA supports something, when a feature has no skill, when a UE4 tutorial's steps do not exist, or before improvising a procedure.
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Three.js (three, WebGL / WebGPU 3D グラフィクス) r186 リファレンス。 Scene, Group, PerspectiveCamera, OrthographicCamera, WebGLRenderer, WebGPURenderer, RenderPipeline、 BufferGeometry, BufferAttribute, StorageBufferAttribute, Mesh, InstancedMesh, SkinnedMesh、 MeshStandardMaterial, MeshPhysicalMaterial, ShaderMaterial, node-materials (TSL)、 DirectionalLight, SpotLight, PointLight, AmbientLight, PMREMGenerator、 GLTFLoader, FBXLoader, DRACOLoader, TextureLoader、 AnimationMixer, AnimationClip, AnimationAction, KeyframeTrack, Timer、 AudioListener, PositionalAudio、 Vector3, Matrix4, Quaternion, Euler, Color, Box3, Raycaster、 OrbitControls, TransformControls, WebXRManager。
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Apple Silicon GPU コンピュート／数値計算リファレンス。MSL (address space, atomic, SIMD-group, TensorOps, cooperative_tensor, matmul2d), threadgroup sizing, argument buffer, indirect command buffer, unified memory, GPU counters, MTLTensor, MTL4MachineLearningCommandEncoder, MPS / MPSGraph / MPSMatrix / MPSNDArray / MPSNNGraph, MLX (mx.array, lazy evaluation, grad / vmap, mx.compile, mx.fft, export_function, mlx.nn, distributed)。
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AMD ROCm / HIP GPU コンピューティングリファレンス。 hipMalloc, hipLaunchKernelGGL, HIP Graph, hipGreenCtx, HIPRTC, hipify, rocBLAS, MIOpen, RCCL, hipThreads, libhipcxx, rocprofv3, amd-smi, rocminfo, TheRock / Core SDK 10, CDNA1-4 / RDNA1-4, MI300 / MI350 / MI350P, gfx942, Matrix Core, wave32/64。
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Renders Hi-C contact matrices honestly and reproducibly with matplotlib, cooltools, HiCExplorer, pyGenomeTracks, FAN-C, CoolBox, and plotgardener. Covers the raw/ICE-balanced/observed-over-expected transform choice, LogNorm vs symmetric-diverging colormaps with vmax/percentile clipping, resolution-to-feature matching (compartments 100-500kb, TADs 10-40kb, loops 5-10kb), square vs rotated-triangle track-stacking, NaN/white-stripe handling, virtual 4C, APA/saddle/on-diagonal pileups, two-condition side-by-side and log2-ratio maps, and interactive (HiGlass) vs scripted-static publication figures. Use when plotting a contact matrix, choosing a normalization or color scale, building a multi-track Hi-C figure, making a virtual 4C profile, piling up loops/boundaries, or comparing two conditions.
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Reads, queries, and writes bigWig indexed binary signal tracks (coverage, fold-change, conservation, methylation-rate) with pyBigWig (Python) and the UCSC Kent tools (bedGraphToBigWig, bigWigToBedGraph, bigWigInfo, bigWigSummary, bigWigAverageOverBed) and deepTools (multiBigwigSummary, computeMatrix, bigwigCompare). Covers the central trap that a wide query returns a precomputed zoom-level summary (by default the mean, which annihilates narrow peaks) not per-base data, when exact=True/values() is mandatory, the NaN-not-zero gap-handling fork, choosing mean vs max vs sum vs coverage by biological question, and the sorted-bedGraph plus chrom.sizes build requirement. Use when extracting signal at regions, computing mean signal per gene/peak, building a browser track from bedGraph, comparing tracks, or building TSS/gene-body metaprofiles.
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Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.
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Detects A/B chromatin compartments from balanced Hi-C contact matrices via eigenvector decomposition of the distance-normalized, Pearson-correlated cis matrix with cooltools (eigs_cis), then orients (phases) the compartment eigenvector against a GC or gene-density track so the active (A) sign is not arbitrary. Covers the eigenvector-is-a-choice problem (per-arm view_df to remove the centromere gradient; picking the eigenvector by max correlation with activity, not by eigenvalue), GC phasing with bioframe.frac_gc, resolution choice (100kb-1Mb), saddle plots and saddle_strength for compartmentalization strength, the cohesin-loss-strengthens-compartments result, subcompartments (SNIPER/Calder/dcHiC), and cross-condition compartment switching. Use when calling A/B compartments, computing E1/eigenvectors, phasing the eigenvector, building saddle plots, choosing a compartment resolution, quantifying compartment strength, or comparing compartmentalization across conditions.
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