Results for “functional”

Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential shifts between conditions. Use when investigating how splicing changes affect protein function.

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Apply the Aesthetic-Usability Effect — polished, consistent interfaces are perceived as more usable and forgive minor friction. Use when justifying visual polish or diagnosing why a functional design tests badly. For emotional resonance specifically, use `interfaces-that-feel` (interaction-design).

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Map functional, emotional, and social jobs with outcome expectations. Use when reframing decisions around motivation rather than features. For who the user is, use `user-persona`.

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Implement a feature from a spec file or description using TDD workflow. Use this skill whenever the user asks to: add a new CLI command, implement a feature from a spec, build new functionality, add a flag, create a new internal package, or write Go code for skillshare. This skill enforces test-first development, proper handler split conventions, oplog instrumentation, and dual-mode (global/project) patterns. If the request involves writing Go code and tests, use this skill — even if the user doesn't explicitly say "implement".

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Helps users discover and install agent skills when they ask questions like "how do I do X", "find a skill for X", "is there a skill that can...", or express interest in extending capabilities. This skill should be used when the user is looking for functionality that might exist as an installable skill.

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Upgrade an existing website or app to premium quality without breaking functionality — audit the current design, identify generic/AI tells, then apply taste and system rules surgically. Use when the user wants to improve, modernize, polish, or "make better" an existing UI/codebase.

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Discover what customers truly need by analyzing the "job" they hire your product to do. Use when the user mentions "customer discovery", "why customers churn", "what job does this solve", "competing against luck", "product-market fit", "switching behavior", "milkshake moment", or "functional vs emotional jobs". Also trigger when investigating why users choose competitors, designing features around real customer needs, or reframing a value proposition. Covers JTBD interviews, competition analysis, and jobs-oriented roadmaps. For product positioning, see obviously-awesome. For rapid validation, see design-sprint. For non-leading interview technique, see mom-test.

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Create aesthetically beautiful interfaces following proven design principles. Use when building UI/UX, analyzing designs from inspiration sites, generating design images with ai-multimodal, implementing visual hierarchy and color theory, adding micro-interactions, or creating design documentation. Includes workflows for capturing and analyzing inspiration screenshots with chrome-devtools and ai-multimodal, iterative design image generation until aesthetic standards are met, and comprehensive design system guidance covering BEAUTIFUL (aesthetic principles), RIGHT (functionality/accessibility), SATISFYING (micro-interactions), and PEAK (storytelling) stages. Integrates with chrome-devtools, ai-multimodal, media-processing, ui-styling, and web-frameworks skills.

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Build Shopify applications, extensions, and themes using GraphQL/REST APIs, Shopify CLI, Polaris UI components, and Liquid templating. Capabilities include app development with OAuth authentication, checkout UI extensions for customizing checkout flow, admin UI extensions for dashboard integration, POS extensions for retail, theme development with Liquid, webhook management, billing API integration, product/order/customer management. Use when building Shopify apps, implementing checkout customizations, creating admin interfaces, developing themes, integrating payment processing, managing store data via APIs, or extending Shopify functionality.

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Manage Model Context Protocol (MCP) servers - discover, analyze, and execute tools/prompts/resources from configured MCP servers. Use when working with MCP integrations, need to discover available MCP capabilities, filter MCP tools for specific tasks, execute MCP tools programmatically, access MCP prompts/resources, or implement MCP client functionality. Supports intelligent tool selection, multi-server management, and context-efficient capability discovery.

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Build MCP (Model Context Protocol) servers using the official @modelcontextprotocol/sdk. Use this skill when users ask to create an MCP server, MCP tools, MCP resources, or want to expose APIs/functionality to AI agents. This skill covers vanilla MCP implementation with Streamable HTTP transport, session management, tools, resources, and prompts.

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Plans and drives cross-functional programs to delivery — scope, sequencing, dependencies, status, risk, and the escalations that keep work moving. Use this to run a multi-team initiative, recover a program that is slipping, build a delivery plan with dependencies, structure status reporting, or diagnose why cross-team work keeps missing dates.

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Raises the visual and interaction quality of an interface — layout, hierarchy, type, spacing, density, and the details that separate a considered product from a generic one. Use this when a screen works but looks unfinished or default, when a layout feels crowded or arbitrary, when a page has no clear focal point, or when an interface needs to feel trustworthy rather than merely functional.

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Owns execution: how work actually gets done across the organization, including process, program management, capacity, vendors, supply chain, and service delivery. Use this when execution is the problem rather than strategy, to design or fix a process, to resolve cross-functional handoff failures, to plan capacity, to assess delivery risk, or when the same failure keeps recurring. Also use to decide whether to build, hire, or outsource a capability.

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Execute a skill's script file with arguments. When you need to run skill functionality, execute specific operations, or process data with skill.

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Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser screenshots, and viewing browser logs.

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Call MCP server tool for extended capabilities. Check 'MCP Servers' section in system prompt for available servers and tools. When you need to use external service or access specialized functionality.

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You MUST use this before any creative work - creating features, building components, adding functionality, or modifying behavior. Explores user intent, requirements and design before implementation.

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Generates complete conventional single-gene oncology research designs from a user-provided cancer context, target gene, and validation direction. Use when a study centers on a fixed candidate gene and needs expression, prognosis, clinicopathologic association, functional interpretation, immune context, genomic or epigenetic context, optional drug-response hypotheses, and orthogonal validation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Designs internal, external, temporal, and functional validation strategies at the protocol stage for medical research studies.

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Extends a mechanistic or association-level biomedical finding into a staged validation pathway that moves from descriptive evidence toward stronger functional support, mechanistic specificity, and clinical relevance. Use this skill when a user has a pathway, biomarker, cell-state, target, mechanism, or association finding and needs to decide what should be validated next, in what order, and which evidence layers are necessary versus optional. Do not default to maximal validation stacks. Build a structured validation ladder with a primary route, stronger upgrade route, and optional extensions.

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Designs QTL colocalization studies that connect eQTL, pQTL, sQTL, or related molecular QTL signals with GWAS loci. Always use this skill whenever a user wants to plan, scope, or structure a locus-level study asking whether a GWAS association and a molecular QTL association may reflect the same underlying causal signal. Covers locus definition, QTL/GWAS source architecture, ancestry and LD alignment, single-locus vs multi-locus strategy, candidate-gene prioritization, optional fine-mapping, linked MR/SMR follow-up, and functional annotation. Always output four workload configurations (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, evidence hierarchy, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references. Never equate colocalization with causality proof, mediation proof, or automatic target validation. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets, repositories, consortia, or public resources.

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Use when starting any creative work - creating features, building components, adding functionality, or modifying behavior. Explores user intent, requirements and design before implementation.

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Master enterprise-grade Scala development with functional programming, distributed systems, and big data processing. Expert in Apache Pekko, Akka, Spark, ZIO/Cats Effect, and reactive architectures. Use PROACTIVELY for Scala system design, performance optimization, or enterprise integration.

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