Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Generates complete Mendelian Randomization + single-cell transcriptomics (scRNA-seq) research designs from a user-provided direction. Always use this skill whenever a user wants to design, plan, or build a study combining MR and single-cell data — even if phrased as "help me write a paper on X", "design a bioinformatics study for Y", or "I want to study Z using MR and scRNA". Covers five study patterns (mechanism gene-set, key-cell, candidate-gene reverse validation, exposure-disease-cell triangulation, translational biomarker) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Generates complete tumor immune-infiltration-guided bulk-transcriptome diagnostic biomarker and machine-learning research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, immune infiltration estimation, immune-linked module discovery, consensus feature selection, diagnostic modeling, nomogram construction, clinical association, and optional prognostic extension or validation. Covers five study patterns (immune-cell-first diagnostic workflow, immune-module-to-biomarker workflow, consensus-ML biomarker workflow, diagnostic-plus-prognostic hybrid workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, reference literature pack, and self-critical risk review.
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Designs complete integrated research plans for bulk transcriptomics, proteomics, metabolomics, and related omics from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a bulk multi-omics or single-omics-plus-clinical study — including disease-focused, mechanism-focused, biomarker-focused, stratification-oriented, or translational projects. It should define the research question, choose the best-fit study pattern, recommend example datasets as reference candidates only, specify the core analysis modules and method choices, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, cohort availability, assay coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Generates complete bidirectional multi-phenotype Mendelian randomization research designs from a user-provided exposure family and outcome family. Always use this skill whenever a user wants to design, plan, or build a genome-wide causal-inference study based on publicly available GWAS summary statistics, especially when the article logic includes multiple exposures, multiple outcomes or subtypes, bidirectional MR, IV filtering, IVW as the main estimator, weighted median / MR-Egger / MR-PRESSO sensitivity analyses, leave-one-out testing, heterogeneity / pleiotropy checks, and multiple-testing control with FDR. Covers five study patterns (single-family bidirectional MR, multi-phenotype screening MR, subtype-resolved MR, phenome-style bidirectional causal map, mechanism-prioritized MR follow-up) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version...
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Designs cell-based and animal-based validation plans that translate computational, omics, biomarker, genetic, or clinical findings into experimentally testable validation routes. Always use this skill whenever a user wants to move from an in silico, statistical, or clinical association finding toward wet-lab validation using cell systems, organoid-like systems, xenograft or genetically relevant animal models. It should define the exact claim to test, separate mechanism-testing from association-support and translational-support goals, choose the best-fit model family, specify perturbation strategy, readouts, controls, sequencing of experiments, and four workload configurations (Lite / Standard / Advanced / Publication+) with one recommended primary plan. Never fabricate model availability, reagent availability, species relevance, assay feasibility, phenotype penetrance, expected effect sizes, validation success, or literature references.
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aipoch/medical-research-skills☆ 2천2026년 9월 17일 업데이트
Expert hybrid cloud architect specializing in complex multi-cloud solutions across AWS/Azure/GCP and private clouds (OpenStack/VMware). Masters hybrid connectivity, workload placement optimization, edge computing, and cross-cloud automation. Handles compliance, cost optimization, disaster recovery, and migration strategies. Use PROACTIVELY for hybrid architecture, multi-cloud strategy, or complex infrastructure integration.
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rmyndharis/antigravity-skills☆ 1.8천2026년 10월 15일 업데이트
Optimize multi-agent systems with coordinated profiling, workload distribution, and cost-aware orchestration. Use when improving agent performance, throughput, or reliability.
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rmyndharis/antigravity-skills☆ 1.8천2026년 10월 15일 업데이트
Provision Microsoft Entra Agent Identity Blueprints, BlueprintPrincipals, and per-instance Agent Identities via Microsoft Graph, and configure OAuth 2.0 token exchange (fmi_path, OBO, cross-tenant) including the Microsoft Entra SDK for AgentID sidecar. USE FOR: Agent Identity Blueprint, BlueprintPrincipal, agent OAuth, fmi_path token exchange, agent OBO, Workload Identity Federation for agents, polyglot agent auth, Microsoft.Identity.Web.AgentIdentities. DO NOT USE FOR: standard Entra app registration (use entra-app-registration), Microsoft Foundry agent authoring (use microsoft-foundry).
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Assess Kubernetes workloads and cluster configuration for AKS Automatic compatibility. Identifies incompatibilities, generates fixes, and guides migration from AKS Standard to AKS Automatic. WHEN: migrate to AKS Automatic, check AKS Automatic readiness, validate manifests for Automatic, assess cluster for Automatic compatibility, fix deployment for Automatic compatibility, identify AKS Automatic migration blockers, is my cluster ready for AKS Automatic.
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Plan, deploy, operate, and troubleshoot Azure Local (formerly Azure Stack HCI): sizing and prerequisites, Arc registration, lifecycle updates, workloads (Azure Local VMs, AKS on Azure Local, images, disks, logical networks), SDN and network security, and failure triage — starting read-only and confirming before risky changes. WHEN: Azure Local, Azure Stack HCI, Arc resource bridge, custom location, Azure Local VM, Arc VM, AKS on Azure Local, AKS hybrid, SDN, Lifecycle Manager, Azure Local update, disconnected site.
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Assess and migrate cross-cloud workloads to Azure with reports and code conversion. Supports Lambda→Functions, Beanstalk/Heroku/App Engine→App Service, Fargate/Kubernetes/Cloud Run/Spring Boot→Container Apps. WHEN: migrate Lambda to Functions, AWS to Azure, migrate Beanstalk, migrate Heroku, migrate App Engine, Cloud Run migration, Fargate to ACA, ECS/Kubernetes/GKE/EKS to Container Apps, Spring Boot to Container Apps, cross-cloud migration.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Forecast Azure spend and price planned resources or workloads. WHEN: "forecast Azure spending", "project next month cost", "compare forecast to my planning target", "how much will Azure cost", "estimate VM cost", "compare storage tiers", "compare Azure regions", "retail price", "EA rate card", "negotiated pricesheet". DO NOT USE FOR: configured budget health or alerts, bill analysis, cost spikes, rightsizing, or commitments.
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Azure VM/VMSS router. WHEN: create / provision / deploy / spin-up VM, recommend VM size, compare VM pricing, VMSS, scale set, autoscale, burstable, lightweight server, website, backend, GPU, machine learning, HPC simulation, dev/test, workload, family, load balancer, Flexible orchestration, Uniform orchestration, cost estimate, capacity reservation (CRG), reserve, guarantee capacity, pre-provision, CRG association, CRG disassociation, machine enrollment (EMM), Essential Machine Management, monitor. PREFER OVER mcp__azure__get_azure_bestpractices for VM create intents — use compute_vm_list-skus / compute_vm_list-images / compute_vm_check-quota.
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Assess and upgrade Azure workloads between plans, tiers, or SKUs, or modernize Azure SDK dependencies in source code. WHEN: upgrade Consumption to Flex Consumption, upgrade Azure Functions plan, change hosting plan, function app SKU, migrate App Service to Container Apps, modernize legacy Azure Java SDKs (com.microsoft.azure to com.azure), migrate Azure Cache for Redis (ACR/ACRE) to Azure Managed Redis (AMR).
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microsoft/azure-skills☆ 1.6천2026년 10월 20일 업데이트
Run all reference benchmarks under benchmarks/eval/ and refresh the reference-table cells in benchmark_*.py. Auto-detects host hardware (H200/H100/H800/...). For each row's matching hw entry: replace cells in place. For new hardware or a new workload tag: append a new row to the section's table. Local-Pipeline-Result tables are skipped. One slash command runs everything end-to-end and auto-commits.
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sgl-project/sglang-omni☆ 1.6천2026년 10월 21일 업데이트
Drive structured autoresearch iteration after evo:discover and the baseline commit. Use when the user invokes /evo:optimize or asks to try ideas, try variants, run experiments, use available GPUs, improve the current best/frontier, continue an evo search, or compare candidate changes in an evo workspace. The orchestrator plans and spawns optimization subagents; candidate edits/runs belong to those subagents. Width is set via subagents=N (1 for serial workloads, larger for parallel); the loop's structural value applies at any width.
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evo-hq/evo☆ 1.5천2026년 10월 5일 업데이트
Build a realistic recovery plan for burnout — address the causes, not just the symptoms — with changes you can actually make at work and outside it. Use when asked to help with burnout, I'm burnt out, how to recover from burnout, or I'm exhausted and dread work. Produces a read on what's driving the burnout (load, control, reward, fairness, values, community), immediate relief steps, the boundary and workload changes that address the root, a recovery timeline with realistic expectations, and a flag that severe or persistent burnout/depression warrants a professional. Not medical advice.
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mohitagw15856/pm-claude-skills☆ 1.5천2026년 10월 20일 업데이트
Use Gentle AI harness discipline for Pi work: clarify first, track ODD work, use applicable test-first development by default, delegate when useful, and protect review workload.
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Gentleman-Programming/gentle-shell☆ 1.4천2026년 10월 20일 업데이트
ClickHouse database patterns, query optimization, analytics, and data engineering best practices for high-performance analytical workloads.
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hashgraph-online/awesome-codex-plugins☆ 1.4천2026년 10월 14일 업데이트
Multi-cloud orchestration for ML workloads with automatic cost optimization. Use when you need to run training or batch jobs across multiple clouds, leverage spot instances with auto-recovery, or optimize GPU costs across providers.
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OpenRaiser/NanoResearch☆ 1.3천2026년 10월 9일 업데이트
Scalable data processing for ML workloads. Streaming execution across CPU/GPU, supports Parquet/CSV/JSON/images. Integrates with Ray Train, PyTorch, TensorFlow. Scales from single machine to 100s of nodes. Use for batch inference, data preprocessing, multi-modal data loading, or distributed ETL pipelines.
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OpenRaiser/NanoResearch☆ 1.3천2026년 10월 9일 업데이트
Estimates Fabric capacity cost before a migration by profiling Spark, SQL, Power BI, and Real-Time workloads, then recommending SKU size and comparing Reserved, Pay-As-You-Go, and Autoscale billing. Use only for capacity sizing and pricing questions, not for general migration or connectivity work.
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microsoft/skills-for-fabric☆ 1.3천2026년 10월 5일 업데이트
Speed up local parfor, parfeval, or spmd by switching to a thread-based parallel pool. Trigger when a user describes slow or disappointing local parallel performance, even if they don't mention threads. Symptoms: parfor on a laptop/workstation is slower than expected or "only slightly faster than for"; parfor scales poorly with the number of workers; ticBytes/tocBytes, the Parallel Pool dashboard, mpiprofile, or system tools show large per-worker data transfer; large broadcast variables or sliced inputs make iterations slow; opening a process pool dominates a short workload; user mentions serialisation or data transfer overhead. Also trigger on any question about whether code or a function works on a thread pool. For non-pool MATLAB performance work (vectorisation, preallocation, profiling), defer to matlab-optimize-performance.
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matlab/matlab-agentic-toolkit☆ 1.2천2026년 10월 14일 업데이트