'confidence' 검색 결과

Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. Use when orthologs are already curated upstream, when the question is "what is the X ortholog of Y" rather than "how to infer orthology de novo", when batch-mapping gene IDs across species, or when comparing the resources for consensus calls. Encodes confidence-level semantics, 1:1 vs 1:many vs many:many, HomoloGene deprecation, and when to defect to de novo computation.

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Query protein-protein and gene interaction databases (STRING, BioGRID, IntAct, SIGNOR, Reactome, HuRI, HuMAP, OmniPath, ConsensusPathDB, DIP). Use when building PPI networks, choosing between physical vs functional vs genetic interactions, signed/directed vs undirected, high-throughput vs curated, picking confidence thresholds, aggregating across resources, or navigating license constraints. Encodes the database decision matrix, STRING v12 channel semantics, OmniPath as meta-database, SIGNOR for signed signaling, and per-resource rate limits.

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Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

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Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

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Synthesizes evidence-linked feedback from validation results, confidence evidence, and iteration triggers. Proposes bounded revision guidance for a stated acceptance failure. Activate on 'synthesize feedback', 'improvement suggestions', 'actionable feedback', 'iteration guidance', 'feedback generation'. NOT for iteration detection (use dag-iteration-detector) or convergence tracking (use dag-convergence-monitor).

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Ahrefs API analyst (extension). Reads referring domains, backlinks, organic keywords, and content explorer data via the tested @ahrefs/mcp@0.0.11 server. Pairs with seo-backlinks for multi-source confidence weighting.

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Estimate task effort from complexity, dependencies, velocity, risk. Structured estimate with confidence levels.

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Reflection-first problem solving methodology for Convex development. Use before implementing any solution to ensure proper root cause analysis, 98% code confidence, and minimal change scope.

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Calculate statistical significance for A/B tests. Sample size estimation, power analysis, and conversion rate comparisons with confidence intervals.

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[62] VALIDATE. Final self-check before delivery. Verify goal alignment, completeness, correctness, and identify residual risks. Produces quality score (0-100) and delivery status. Use when completing any significant work, before handoff, or when you need confidence that work is ready.

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[23] UNDERSTAND. Consult external AI models when internal sources are exhausted. Build quality prompts using Prompt150 formula (Context + Query + Method + Style). Use when Loop150 exhausts internal sources, need real-world precedents, confidence <75%, or require reasoning from specialized AI models.

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Decision framework for choosing between regex and LLM when parsing structured text — start with regex, add LLM only for low-confidence edge cases.

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Instinct-based learning system that observes sessions via hooks, creates atomic instincts with confidence scoring, and evolves them into skills/commands/agents. v2.1 adds project-scoped instincts to prevent cross-project contamination.

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Audit trail, confidence tagging, and ethical checks on every AI decision your operator produces.

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Maxim 3D CGI product render — engineered for purchase confidence and premium positioning. Uses Material Realism + Endowment Effect + Photorealism Trust Signals to move premium-product viewers toward purchase. Use for luxury product reveals, architectural visualization, tech hardware marketing, high-ticket commerce.

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Atom of Thoughts (AoT) reasoning - decompose complex problems into atomic units with confidence tracking and backtracking. For genuinely complex reasoning, not everyday questions. Triggers on: atomise, complex reasoning, decompose problem, structured thinking, verify hypothesis.

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Human verification for AI agents. Submit claims, draft responses, or observation requests to human domain experts via the 2O API. Returns structured verdicts with confidence scores and evidence.

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Refactor code with confidence using comprehensive test safety net:

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Detects AI-generated deepfake audio used in voice phishing (vishing) attacks by extracting spectral features (MFCC, spectral centroid, spectral contrast, zero-crossing rate) and classifying samples with machine learning models. Supports batch analysis of audio files, generates confidence scores, and produces forensic reports. Activates for requests involving deepfake voice detection, vishing investigation, AI-generated speech analysis, voice cloning detection, or audio authenticity verification.

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Analyzes indicators of compromise (IOCs) including IP addresses, domains, file hashes, URLs, and email artifacts to determine maliciousness confidence, campaign attribution, and blocking priority. Use when triaging IOCs from phishing emails, security alerts, or external threat feeds; enriching raw IOCs with multi-source intelligence; or making block/monitor/whitelist decisions. Activates for requests involving VirusTotal, AbuseIPDB, MalwareBazaar, MISP, or IOC enrichment pipelines.

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Comprehensive OSINT methodology for external red-team operations and authorized attack-surface assessments. Covers the 5-stage recon pipeline (seed discovery, asset expansion, enrichment, exposure analysis, reporting), asset-graph discipline with 29 asset types, severity rubric (CRITICAL/HIGH/MEDIUM/LOW/INFO), confidence upgrade workflows, time budgeting, asset-level triage rules, scale-based tactics, identity-fabric mapping (Entra/Okta/ADFS/Google/SAML/M365 Teams+SharePoint+OAuth), API and auth-map methodology, JavaScript deep analysis, mobile attack surface, cloud attack surface, breach×identity correlation, detectability tagging, detection-aware probing (back-off, persona rotation), read-only validator discipline, WAF/CDN bypass + origin discovery, vulnerability prioritization (CVE/EPSS/KEV), phishing infrastructure planning + pretext development, bug bounty submission templates, client deliverable templates with risk translation, threat-actor investigation (incl. RU/CN pivots), cryptocurrency tracing,...

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Intelligent search for agents. Multi-source retrieval with confidence scoring - web, academic, and Tavily in one unified API.

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