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概要と使いどころ
"Apply information economics to diagnose and remedy market failures caused by asymmetric information. Use this skill when the user needs to analyze adverse selection, moral hazard, or signaling and screening mechanisms, especially in insurance, labor, credit, or product quality markets.".
日本語の概要は準備中です。原文の説明を表示しています。
"Apply network economics to analyze markets with network effects, critical mass dynamics, and platform competition. Use this skill when the user needs to evaluate tipping points, lock-in risks, switching costs, or standards wars, especially in technology platforms and two-sided markets.".
日本語の概要は準備中です。原文の説明を表示しています。
"Apply platform economics to analyze network effects, solve chicken-and-egg problems, and design multi-sided platform pricing strategies. Use this skill when the user needs to evaluate a platform business model, diagnose why a platform is failing to scale, or choose a subsidy strategy for bootstrapping a two-sided market.".
日本語の概要は準備中です。原文の説明を表示しています。
Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.
日本語の概要は準備中です。原文の説明を表示しています。
"Analyze unit economics to evaluate per-unit profitability and business model scalability. Use this skill when the user needs to assess whether each transaction, customer, or product unit is profitable, evaluate startup viability, or optimize contribution margins — even if they say 'does our business model work', 'what's our margin per order', or 'can we scale profitably'.".
日本語の概要は準備中です。原文の説明を表示しています。
Partner, channel, and ecosystem marketing for B2B SaaS — and the design of the partner program itself. Use this skill for co-marketing with technology alliances and channel partners, integration launches, joint campaigns and content, partner tiering and enablement, cloud-marketplace go-to-market (AWS, Azure, GCP listings, private offers, committed-spend drawdown), and for channel program architecture: whether to launch a partner program at all, which motions to run (referral, technology, services/SI, reseller), partner unit economics, margin and SPIF design, partner recruitment and certification ramp, and the rules of engagement that settle a contested deal. Also triggers on: partner marketing, co-marketing, channel, reseller, VAR, MSP, distributor, OEM, alliance, ecosystem, integration launch, marketplace listing, AWS Marketplace, private offer, MDF, joint webinar, co-branded, channel conflict, rules of engagement, deal registration, partner program design, should we build a partner program, partner economics, partner P&L, partner CAC, margin stacking, SPIF, rebate, partner recruitment, partner onboarding, partner certification, partner tiers, our partners signed up and never sold anything.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a task needs the judgment of an Economics Teacher, Postsecondary — designing an intro micro/macro sequence for a mostly-terminal non-major audience, diagnosing a miskeyed or poorly discriminating exam item, calibrating TA grading on graphical or free-response problem sets, or investigating a spike in homework answers matching an online solution bank.
日本語の概要は準備中です。原文の説明を表示しています。
Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models, cross-reference with clinical trials and drug databases, or conduct any disease-focused, pathology-driven, or clinical variant interpretation workflow. Covers the full pipeline from disease-tissue mapping through GWAS variant annotation, heritability enrichment, cancer epigenomics, drug target identification, and clinical trial cross-referencing. Integrates ENCODE with Open Targets, PubMed, ClinicalTrials.gov, and bioRxiv.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze franchise and multi-location unit economics including per-location P&L construction, four-wall EBITDA margins, prime cost optimization, contribution margin analysis, break-even modeling, and store-level ROI calculations.
日本語の概要は準備中です。原文の説明を表示しています。
Modern genetics expert covering Mendelian genetics, molecular genetics, genomics, and CRISPR technologies
日本語の概要は準備中です。原文の説明を表示しています。
法外功夫 — Non-legal business skills for lawyers. Decision analysis, game theory, contract design, accounting, finance, microeconomics, law & economics, statistics, and regression analysis distilled into deep, actionable frameworks for legal practice. Each domain includes formulas with LaTeX notation, worked examples, adversarial checklists, and book-aligned structure. | 律师必备的非法律商业技能深度参考：决策分析、博弈论、合同设计、会计、金融、微观经济学、法经济学、统计分析、多元回归。每章都包含完整公式推导、worked examples、对抗清单与经典判例。当用户涉及和解谈判、合同激励、财务尽调、企业估值、损害赔偿计算、反垄断分析、统计证据评估、歧视诉讼回归分析、hold-up、效率违约、Daubert 动议等场景时触发。
日本語の概要は準備中です。原文の説明を表示しています。
Calculates statistical power for high-dimensional genomics experiments (bulk RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, methylation, proteomics) under negative-binomial count models using RNASeqPower, PROPER, and simulation via powsimR, distinguishing per-gene from marginal (transcriptome-wide) power, the role of mean expression and dispersion, and the sequencing-depth-versus-replicate tradeoff. Covers simulation as the honest default for overdispersed counts, FDR-aware average power versus single-test power, observed/post-hoc power as an anti-pattern, and the winner's-curse / Type-S / Type-M consequences of underpowering. Use when planning replicate number for a sequencing experiment, deciding whether to add depth or samples, choosing closed-form versus simulation power, estimating power from pilot dispersions, or justifying replication in a grant. For clinical-trial power see clinical-biostatistics/power-and-sample-size; for the inverse sample-size question see experimental-design/sample-size.
日本語の概要は準備中です。原文の説明を表示しています。
Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.
日本語の概要は準備中です。原文の説明を表示しています。
Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.
日本語の概要は準備中です。原文の説明を表示しています。
Build and analyze pangenomes for prokaryotes (Panaroo, PPanGGOLiN, PEPPAN, GET_HOMOLOGUES, anvi'o pangenomics) and eukaryotes (Minigraph-Cactus, PGGB, vg pangenome graphs). Implement Tettelin core/accessory/cloud genome decomposition (Tettelin 2005), Heap's law open/closed pangenome modeling, gene presence/absence GWAS (Scoary, pyseer), pangenome graph variant calling (vg, PanGenie), and structural-variation graph indexing. Use when assembling species- or genus-level pan-gene catalogs, separating core from accessory/shell/cloud genes, testing gene-content associations with phenotypes, building pangenome graphs from haplotype-resolved assemblies, calling SVs from pangenome graphs, or selecting between bacterial-pangenome and eukaryotic-pangenome workflows.
日本語の概要は準備中です。原文の説明を表示しています。
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Given an article DOI or PubMed ID, discover and download the genomics data files deposited by the authors (VCF, FASTA, H5AD, CSV, JSON, BAM, etc.) from public repositories such as GEO, ENA, Zenodo, Figshare, Dryad, and OSF.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze credential pooling operations and API reseller business models — economics, risks, detection patterns, and sustainability
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/pharmacogenomics/annotations. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/multiomics. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/multiomics/methods. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/pharmacogenomics/visualization. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/multiomics/survival. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory src/metainformant/multiomics/visualization. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。