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Fallback for general coding work that does not match any specific sextant sub-skill. Use for lightweight tasks: config changes, style fixes, utility functions, one-off scripts, or tasks too small to warrant a dedicated workflow. All dedicated sub-skills take priority over this one — check these first: sextant:fix-bug (broken behavior), sextant:debug (unknown bug location), sextant:add-feature (new functionality), sextant:modify-feature (changing existing behavior), sextant:review-code (evaluating code), sextant:write-tests (test coverage), sextant:refine-requirements (ambiguous scope), sextant:plan (multi-step sequencing), sextant:ship (release prep), sextant:migrate (cross-module upgrade), sextant:security (vulnerability audit). Only use this skill when none of the above match.

日本語の概要は準備中です。原文の説明を表示しています。

Rembric dashboard UI work (dark monochrome zinc surfaces, lime accent, Geist type, Spectrum data-tables) — building / editing / extending pages, styles, components, modals, tables, filters, pagination, mobile responsive, destructive confirmations. Use when the user asks for changes under `apps/web/src/app/dashboard/` or `apps/web/src/components/dashboard/`, mentions Rembric design tokens (lime, zinc, command bar, StatusPill, hl-lime, data-table), or requests a new dashboard page / form / table.

日本語の概要は準備中です。原文の説明を表示しています。

Apply rapport-based elicitation to resistant or semi-cooperative humans and agents. Use when coercive prompting or brittle handoffs damage cooperation. NOT for routine cooperative tasks, pure technical debugging, or already reliable exchanges.

日本語の概要は準備中です。原文の説明を表示しています。

Manage database schema with Drizzle ORM and SQLite migrations. Use when adding tables, modifying columns, creating indexes, or running migrations. Activates for database schema changes, migration generation, and Drizzle query patterns.

日本語の概要は準備中です。原文の説明を表示しています。

Audits git repository hygiene: worktree state, stale branches, uncommitted changes, orphaned worktrees, and hook configuration. Finds the rot before it causes a crisis.

日本語の概要は準備中です。原文の説明を表示しています。

Cloudflare Pages and Workers deployment checklist for wrangler deploys, secret audits, D1 migrations, Worker-compatible SDK checks, and browser-auth verification. Use when shipping Cloudflare changes to production. NOT for general CI/CD architecture, non-Cloudflare deployments, or post-launch UX QA.

日本語の概要は準備中です。原文の説明を表示しています。

Safe database migration manager for zero-downtime DDL changes and rollback plans. Activate on: database migration, schema change, DDL, rollback plan, zero-downtime migration, Prisma migrate, Drizzle kit, Flyway, column rename, table alter. NOT for: query optimization (use database-optimizer), ORM modeling (use data-pipeline-engineer), backup/restore (use devops-automator).

日本語の概要は準備中です。原文の説明を表示しています。

Decides HOW to mutate a DAG when a node fails, quality is below threshold, or new information changes the plan. Selects from mutation strategies (add node, replace agent, fork paths, loop back, downgrade model) based on failure type, cost budget, and execution history. Activate on "DAG failed how to fix", "mutation strategy", "replan on failure", "adaptive DAG", "recovery strategy", "what to do when node fails". NOT for detecting failures (use dag-quality), executing mutations (use dag-planner), or runtime execution (use dag-runtime).

日本語の概要は準備中です。原文の説明を表示しています。

Verifies build output integrity after code changes. Runs builds, validates artifact structure, checks for regressions in bundle size, asset references, and static export completeness. The last line of defense before a bad deploy ships.

日本語の概要は準備中です。原文の説明を表示しています。

Choosing and operating an HTTP API versioning strategy that doesn't break clients — Stripe's date-based pinned versions, the Deprecation/Sunset header pair (RFC 9745 + RFC 8594), URI vs header vs media-type approaches, and the version-transformer pattern. Grounded in Stripe's published architecture and IETF RFCs.

日本語の概要は準備中です。原文の説明を表示しています。

Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).

日本語の概要は準備中です。原文の説明を表示しています。

Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.

日本語の概要は準備中です。原文の説明を表示しています。

Identify differentially bound regions across CLIP-seq conditions (knockdown vs control, treatment vs vehicle, disease vs healthy) using DEWSeq (sliding-window DESeq2), Flipper (Skipper-downstream), ASpeak, edgeR, or limma-voom. Use when computing condition-level changes in RBP binding intensity, choosing peak-level vs window-level vs crosslink-level testing, designing replicate experiments, or distinguishing biological binding shifts from technical confounders.

日本語の概要は準備中です。原文の説明を表示しています。

Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF calibration (BF >6 ≈ 90% posterior per Hart 2017; ~5% FDR by BAGEL convention). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies differentially bound ChIP-seq regions between conditions using DiffBind, csaw (sliding windows), DESeq2/edgeR/PyDESeq2 on count matrices, NormR (control-aware), or MAnorm2. Distinguishes three distinct normalization problems (composition bias, trended bias, global shifts) and matches each to its appropriate fix including spike-in scaling. Use when comparing ChIP-seq binding between experimental conditions, choosing normalization for global vs local changes, integrating spike-in data, or reconciling DiffBind/DESeq2 disagreement.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses Tanner stage to determine if physical changes of puberty have begun (stage G2/B2 or higher) for considering pubertal suppression. Triggered when a clinician evaluates pubertal development in an adolescent patient.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses a patient’s ability to operate an insulin pump and make setting changes, evaluating dexterity, vision, mental health, and cognition for independent or assisted use. Triggered by phrases such as 'Check patient can manipulate pump controls' and 'Evaluate dexterity and vision for pump use'.

日本語の概要は準備中です。原文の説明を表示しています。

This skill directs lifelong treatment of cardiovascular risk factors, osteoporosis, and psychiatric symptoms in all patients with Cushing's syndrome until biochemical resolution of hypercortisolism. Use when managing any CS patient for long‑term comorbidity control; triggers include persistent hypertension, dyslipidemia, low bone density, depression, anxiety, or cognitive changes in the setting of known or suspected CS.

日本語の概要は準備中です。原文の説明を表示しています。

This skill guides annual evaluation of patients with primary adrenal insufficiency (PAI) for symptoms and signs of glucocorticoid and mineralocorticoid over- or under-replacement. Use during annual follow-up when assessing for weight changes, blood pressure abnormalities, edema, or symptoms such as fatigue, insomnia, or salt craving.

日本語の概要は準備中です。原文の説明を表示しています。

Execute a swarm plan wave by wave with filesystem isolation via git worktrees. For each wave, main context decides the scenario recipe + implementation contract for every task, then spawns one swarm-worker per task in parallel. Each worker executes its recipe and reports JSON status. Worktree merge-audit verifies write-set discipline before changes land on main. Aborts remaining waves on any audit or task failure.

日本語の概要は準備中です。原文の説明を表示しています。

Workflow track for tasks that need no TDD — documentation edits, governance count bumps, vendored-skill content updates, configuration tweaks, formatting, typo fixes, dependency bumps where no project code changes. Skips `/scenario` and `/implement` (no failing test to drive) and runs the work directly. `archive`, `memory-sync`, `/grant-commit`, and `/commit` remain mandatory. `verify`, `simplify`, `integrate`, and `document` are conditional — required when the diff hits one of the listed triggers, optional otherwise. `verify` is skipped only when the diff is pure-docs/prose AND `project.json → test.kind` is `behavior` (absent/invalid `test.kind` → `structural` → verify runs). Chore is a stripped-down pipeline, not a bypass; never silently skip a conditional phase whose triggers apply.

日本語の概要は準備中です。原文の説明を表示しています。

Workflow Phase 8 (optional) — OWASP-aligned security review of pending code changes. Produces a prioritized findings report (Critical/High/Medium/Low) mapped to OWASP Top 10 and CWE IDs. Output at `docs/security/<slug>-<date>.md`. Read-only.

日本語の概要は準備中です。原文の説明を表示しています。

Cross-consistency review of a drafted spec's diagrams. Verifies that C4 components appear in the dependency graph, class-diagram changes have matching DDL, every AC resolves to a concrete sequence, and the dependency graph is acyclic. Read-only. Run after `/spec-lint` passes and before implementation.

日本語の概要は準備中です。原文の説明を表示しています。