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概要と使いどころ
The FDA Adverse Event Reporting System (FAERS) is a database used for the spontaneous reporting of adverse events and medication errors related to human drugs and therapeutic biological products. faers pacakge serves as the interface between the FAERS database and R. Furthermore, faers pacakge offers a standardized approach for performing pharmacovigilance analysis.
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MHC (major histocompatibility complex) molecules are cell surface complexes that present antigens to T cells. The repertoire of antigens presented in a given genetic background largely depends on the sequence of the encoded MHC molecules, and thus, in humans, on the highly variable HLA (human leukocyte antigen) genes of the hyperpolymorphic HLA locus. More than 28,000 different HLA alleles have been reported, with significant differences in allele frequencies between human populations worldwide
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Microbiome time series simulation with generalized Lotka-Volterra model, Self-Organized Instability (SOI), and other models. Hubbell's Neutral model is used to determine the abundance matrix. The resulting abundance matrix is applied to (Tree)SummarizedExperiment objects.
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Universal LaTeX document skill: create, compile, and convert any document to professional PDF with PNG previews. Supports resumes, reports, cover letters, invoices, academic papers, theses/dissertations, academic CVs, presentations (Beamer), scientific posters, formal letters, exams/quizzes, books, cheat sheets, reference cards, exam formula sheets, fillable PDF forms (hyperref form fields), conditional content (etoolbox toggles), mail merge from CSV/JSON (Jinja2 templates), version diffing (latexdiff), charts (pgfplots + matplotlib), tables (booktabs + CSV import), images (TikZ), Mermaid diagrams, AI-generated images, watermarks, landscape pages, bibliography/citations (BibTeX/biblatex), multi-language/CJK (auto XeLaTeX), algorithms/pseudocode, colored boxes (tcolorbox), SI units (siunitx), Pandoc format conversion (Markdown/DOCX/HTML ↔ LaTeX), and PDF-to-LaTeX conversion of handwritten or printed documents (math, business, legal, general). Compile script supports pdflatex, xelatex, lualatex with auto-detection, latexmk backend, texfot log filtering, PDF/A output, and verbosity control (--verbose/--quiet). Empirically optimized scaling: single agent 1-10 pages, split 11-20, batch-7 pipeline 21+. Use when user asks to: (1) create a resume/CV/cover letter, (2) write a LaTeX document, (3) create PDF with tables/charts/images, (4) compile a .tex file, (5) make a report/invoice/presentation, (6) anything involving LaTeX or pdflatex, (7) convert/OCR a PDF to LaTeX, (8) convert handwritten notes, (9) create charts/graphs/diagrams, (10) create slides, (11) write a thesis or dissertation, (12) create an academic CV, (13) create a poster, (14) create an exam/quiz, (15) create a book, (16) convert between document formats (Markdown, DOCX, HTML to/from LaTeX), (17) generate Mermaid diagrams for LaTeX, (18) create a formal business letter, (19) create a cheat sheet or reference card, (20) create an exam formula sheet or crib sheet, (21) condense lecture notes/PDFs into a cheat sheet, (22) create a fillable PDF form with text fields/checkboxes/dropdowns, (23) create a document with conditional content/toggles (show/hide sections), (24) generate batch/mail-merge documents from CSV/JSON data, (25) create a version diff PDF (latexdiff) highlighting changes between documents, (26) create a homework or assignment submission with problems and solutions, (27) create a lab report with data tables, graphs, and error analysis, (28) encrypt or password-protect a PDF, (29) merge multiple PDFs into one, (30) optimize/compress a PDF for web or email, (31) lint or check a LaTeX document for common issues, (32) count words in a LaTeX document, (33) analyze document statistics (figures, tables, citations), (34) fetch BibTeX from a DOI, (35) convert a Graphviz .dot file to PDF/PNG, (36) convert a PlantUML .puml file to PDF/PNG, (37) create a one-pager/fact sheet/executive summary, (38) create a datasheet or product specification sheet, (39) extract pages from a PDF (page ranges, odd/even), (40) check LaTeX package availability before compiling, (41) analyze citations and cross-reference with .bib files, (42) debug LaTeX compilation errors, (43) make a document accessible (PDF/A, tagged PDF), (44) create lecture notes or course handouts, (45) fill an existing PDF form (fillable fields or non-fillable with annotations), (46) extract text or tables from a PDF (pdfplumber, pypdf), (47) OCR a scanned PDF to text (pytesseract), (48) create a PDF programmatically with reportlab (Canvas, Platypus), (49) rotate or crop PDF pages (pypdf), (50) add a watermark to an existing PDF, (51) extract metadata from a PDF (title, author, subject).
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Expert knowledge for Azure Reliability development including best practices, decision making, architecture & design patterns, limits & quotas, and deployment. Use when choosing Azure regions, availability zones, geo-paired deployments, Queue Storage limits, or Web PubSub apps, and other Azure Reliability related development tasks. Not for Azure Monitor (use azure-monitor), Azure Resiliency (use azure-resiliency), Azure Service Health (use azure-service-health), Azure Sre Agent (use azure-sre-agent).
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Expert knowledge for Azure Managed Applications development including limits & quotas, security, configuration, and deployment. Use when designing createUiDefinition UIs, JIT access, managed identities, StorageAccountSelector, or Bicep-based catalog publishing, and other Azure Managed Applications related development tasks. Not for Azure Blueprints (use azure-blueprints), Azure Resource Manager (use azure-resource-manager), Azure Lighthouse (use azure-lighthouse), Azure Partner Solutions (use azure-partner-solutions).
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Expert knowledge for Azure Managed Grafana development including troubleshooting, decision making, limits & quotas, security, configuration, and integrations & coding patterns. Use when configuring MCP/AI Foundry dashboards, Prometheus/AKS or ADX data sources, private endpoints, or Enterprise upgrades, and other Azure Managed Grafana related development tasks. Not for Azure Monitor (use azure-monitor).
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Expert knowledge for Azure Functions development including troubleshooting, best practices, decision making, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when wiring Functions to HTTP/storage/queues, securing with VNets/MI, tuning scaling, or deploying via CI/CD, and other Azure Functions related development tasks. Not for Azure App Service (use azure-app-service), Azure Logic Apps (use azure-logic-apps), Azure Container Apps (use azure-container-apps), Azure Kubernetes Service (AKS) (use azure-kubernetes-service).
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Expert knowledge for Azure Container Storage development including troubleshooting, decision making, limits & quotas, security, and configuration. Use when configuring Elastic SAN-backed pools, CMK encryption, LRS/ZRS redundancy, volume resizing, or Prometheus/Grafana monitoring, and other Azure Container Storage related development tasks. Not for Azure Blob Storage (use azure-blob-storage), Azure Files (use azure-files), Azure Elastic SAN (use azure-elastic-san), Azure NetApp Files (use azure-netapp-files).
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One lifecycle poll over everything vuln-scanner produces - PR and advisory status, PVR triage transitions, and pending-disclosure aging, with a stars-secured impact headline and one action queue.
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Audit trending repos for real security vulnerabilities and disclose responsibly - scan and route findings (PVR / dependency PR), re-submit queued advisories, and send armed email disclosures
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Watch your GitHub repos across four views - a combined urgency monitor (stale PRs, new issues, releases), a new-issue triage queue, a release upgrade digest, or your own opened-PR tracker.
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Use ONLY when calling the `browser_execute` tool or driving a real browser via the Chrome DevTools Protocol. Required reading before the first `browser_execute` call in a session. Covers the three connection methods (local Chrome with remote debugging, isolated debug-port profile, Browser Use cloud), the in-process `session` / `console` snippet model, attaching to a page target, common CDP commands, the per-project `.bcode/agent-workspace/` for reusable scripts, and screenshot auto-attachment.
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Interactive loop that builds and tunes an AI prompt for evaluating whether a company fits a client's ICP. Run after any list-building skill (disco-like, blitz-list-builder, google-maps-list-builder, prospeo-full-export) to qualify companies before scaling. Iterates batches of 10 companies with user feedback, stops when 2 consecutive rounds have zero corrections, saves the final prompt for reuse. Always uses Claude Code Task sub-agents — never an external API key.
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Reusable approval-loop pattern for fanning out lead personalization across parallel Claude Code Task sub-agents. Shows the user 1 sample personalization, collects feedback, runs 10 more, approves, runs 10 more — stops when 2 consecutive rounds have zero edits, then scales to the full list. ALWAYS uses Claude Code Task tool sub-agents — never an external Anthropic/OpenAI API key. Use when any skill needs per-lead custom variables (situation lines, value lines, CTAs).
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Pulls replies from a Smartlead campaign, classifies each as positive/neutral/negative/OOO/bounce/unsubscribe using Claude, and reports the positive reply rate — the north-star metric for cold email. Use when the user wants to know if a campaign is actually working (not just getting replies, but getting the RIGHT replies). Triggers on "score my replies", "how's campaign X doing", "positive reply rate", "is this campaign working".
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Identify and neutralize buyer objections. Trigger on "why wouldn't someone buy", "objections", "hesitation", "conversion issues".
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Create a comprehensive brand standards document — covering logo usage, color, typography, voice, messaging, and application rules. Use when the user says "brand guidelines", "brand standards", "brand book", "style guide", "brand guide", "brand manual", "brand rules", "brand documentation", "brand toolkit", "onboarding designers or copywriters", "need a document for the team", "brand consistency across teams", or wants to codify all brand decisions into a reusable reference document.
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Build a repeatable eval loop that grades agent output with an LLM judge, so prompt/skill changes get scored against a baseline instead of eyeballed. Reuses loopkit's verifier subagent as the grader — do not build a new one.
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Use when the user mentions Higgsfield Canvas, a node-based or node graph workspace, an infinite board/canvas, chaining generations into a pipeline, or wants to wire prompts → images → videos across models on one surface. Covers what Canvas is, the node categories, the seven models that run inside Canvas, the named canvas patterns (Simple Seedance, Extend Video, Image Edit, StoryBoard With Elements, Long Video fan-out), the build-free / generate-paid cost model, reusable templates, assets-as-nodes, and Shared Canvas live collaboration. Also trigger on 'Higgsfield ComfyUI alternative', 'node workflow', or 'connect nodes to build a scene/campaign'.
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Use when the user asks about audio in Higgsfield videos, needs to add dialogue or lip-sync, wants sound effects or ambient sound in generated video, asks about music or BGM in output, or is using any audio-capable model (Kling 3.0, Seedance 1.5 Pro, Seedance 2.0, Veo 3/3.1, Grok Video / Grok Imagine). Also use when the user's prompt would benefit from audio direction but they haven't mentioned it. Also use when the user wants standalone audio — a soundtrack, ambience bed, multi-speaker scene audio (Seed Audio 1.0), or text-to-speech voiceover. Also use to swap or revoice the speaker in an existing video (voice_change), or to clone / create a reusable voice (create_voice → a voice_type 'element' voice usable in TTS and voice change).
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Writes the character-performance layer of a video prompt as behavior under pressure, not displayed emotion — objective, obstacle, tactics, beats, subtext, listening, body/status/proxemics, and mandatory eye life. Produces a reusable 150–220-word acting master profile per character plus a per-scene rewrite of it, and a locked voice prompt. Use whenever a prompt needs acting, performance, or emotion direction; whenever characters read wooden, dead-eyed, or 'AI'; whenever a character must stay themselves across many shots; or when the user asks for character behavior, mannerisms, tics, a gait, or how someone reacts. Pairs with higgsfield-facs (muscle-level AU codes) and higgsfield-seedance (the prompt the paragraph goes into).
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Use this skill when the user wants an evidence-based research memo, literature review, market/policy/technical landscape, or a multi-source decision brief with citations, trade-offs, and a clear conclusion. Best for tasks that need synthesis across multiple external sources, iterative follow-up research, or a reusable written artifact. Do not use for quick factual lookups, single-source summaries, simple Q&A, summarizing one document the user already provided, plan-only requests where the user explicitly defers the actual research, or when the user wants a short answer with no need for cited evidence (a short but evidence-backed conclusion is still a brief memo, which this skill covers). Chinese trigger examples: "帮我调研", "深度研究", "综述报告", "技术选型分析", "竞品研究", "政策分析".
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专业微信公众号文章助手，支持四个独立且可组合模式：article 写正文；image-prompts 从文章生成版本化、provider-neutral 的图片提示词 manifest 与稳定占位符，但不调用生图；layout 把文章和 manifest 确定性转换为微信安全的内联 HTML；full-pipeline 串联正文、提示词/占位符和排版。用户提到公众号、微信文章、推文、配图提示词、图片 manifest、公众号排版、内联 HTML 或完整图文流水线时触发。支持企业官号、个人技术博客、活动回顾和产品评测。不用于：带引用的研究报告（用 deep-research）、PPT/组图（用 deck-studio）、英文文章、仅润色一小段。永不自动发布，永不把提示词或占位符声称为已生成图片。
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