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Discovers de novo motifs and tests known motif enrichment in ChIP-seq, ATAC-seq, or other peak sequences using HOMER, MEME-ChIP (STREME, CentriMo, TOMTOM, FIMO), monaLisa, and AME. Handles background selection (GC-matched, dinucleotide-shuffled, Markov order-2, peak-flanks), motif databases (JASPAR 2024 CORE PWMs, JASPAR 2026 deep-learning collection, HOCOMOCO v12, HOMER built-in), centrally-enriched motif testing, and differential motif analysis. Use when identifying TF binding motifs in peaks, testing for known TF enrichment, scanning for motif instances, comparing motif content between conditions, or interpreting motifs from deep learning models.

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Trains and applies base-resolution deep learning models on ChIP-seq / ChIP-nexus / CUT&RUN data. Uses BPNet (Avsec 2021 Nat Genet 53:354; soft motif syntax from ChIP-nexus), chromBPNet (Pampari A et al 2024 bioRxiv; bias-factorized base-resolution profiles), EnFormer (Avsec 2021 Nat Methods 18:1196; 196 kb input, ~100 kb effective receptive field), DeepSEA (Zhou 2015; multi-task CNN), and JASPAR 2026 deep-learning collection (1259 BPNet ChIP models). Performs in silico mutagenesis for variant-effect prediction, DeepLIFT/Grad attribution, and TF-MoDISco motif discovery from attribution scores. Use when predicting variant effects on TF binding, discovering soft motif syntax / cooperativity, integrating ChIP-seq with sequence-only predictions, or applying precomputed JASPAR Deep Learning models to new variants.

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Standardizes molecular structures using the ChEMBL structure pipeline for normalization and parent selection plus RDKit rdMolStandardize for explicit custom steps such as tautomer canonicalization, salt/solvent stripping, charge handling, stereochemistry handling, mixture selection, and isotope normalization. Explicitly compares ChEMBL, canSARchem, RDKit, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

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Use when the user wants automated performance profiling, headless Instruments analysis, or CLI-based trace collection.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user mentions SwiftUI performance, janky scrolling, slow animations, or view update issues — expensive bodies, formatters, whole-collection dependencies, and missing lazy containers.

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Apply modern Swift language patterns and idioms for non-concurrency, non-SwiftUI code. Covers if/switch expressions (Swift 5.9+), typed throws (Swift 6+), result builders, property wrappers, opaque and existential types (some vs any), guard patterns, Never type, Regex builders (Swift 5.7+), basic Codable shaping (CodingKeys, custom decoding, nested containers), modern collection APIs (count(where:), contains(where:), replacing()), basic FormatStyle usage, and string interpolation patterns. Use when writing core Swift code involving generics, protocols, enums, closures, or modern language features; route deep Codable to swift-codable, detailed formatting/localization to swift-formatstyle, and API naming to swift-api-design-guidelines.

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Build SwiftUI layouts using stacks, grids, lists, scroll views, forms, and controls. Covers VStack/HStack/ZStack, LazyVGrid/LazyHGrid, List with sections and swipe actions, ScrollView with ScrollPosition and scroll-driven reveal surfaces, Form with validation, Toggle/Picker/Slider, .searchable, and overlay patterns. Use when building data-driven layouts, collection views, paged detail reveals, settings screens, search interfaces, or transient overlay UI.

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Read, write, and query Apple Health data using HealthKit. Covers HKHealthStore authorization, sample queries, statistics queries, statistics collection queries for charts, saving HKQuantitySample data, background delivery, workout sessions with HKWorkoutSession and HKLiveWorkoutBuilder, HKUnit, and HKQuantityTypeIdentifier values. Use when integrating with Apple Health, displaying health metrics, recording workouts, or enabling background health data delivery.

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Generate read-only MongoDB queries (find) or aggregation pipelines using natural language, with collection schema context and sample documents. Use this skill whenever the user asks to write, create, or generate MongoDB queries, wants to filter/query/aggregate data in MongoDB, asks "how do I query...", needs help with query syntax, or discusses finding/filtering/grouping MongoDB documents. Also use for translating SQL-like requests to MongoDB syntax. Does NOT handle Atlas Search ($search operator), vector/semantic search ($vectorSearch operator), fuzzy matching, autocomplete indexes, or relevance scoring - use search-and-ai for those. Does NOT analyze or optimize existing queries - use mongodb-query-optimizer for that. Does NOT handle aggregation pipelines that involve write operations. Requires MongoDB MCP server.

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Run MATLAB test suites and analyze results, including test filtering, parallel execution, result diagnostics, code coverage collection, gap analysis, and CI/CD with buildtool. Use when running tests, filtering test suites, analyzing test failures, checking, collecting, or analyzing coverage, justifying uncovered code, or configuring CI pipelines. Do NOT use for writing, generating, or structuring tests. Do NOT use for Simulink coverage or Simulink testing workflows.

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Deploy, manage, and optimize vector databases for AI applications. Covers Qdrant, Weaviate, pgvector, and Pinecone — collection management, indexing strategies, backup, and performance tuning for production RAG and semantic search workloads.

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Configure Grafana Loki for log aggregation and analysis. Set up Promtail for log collection, write LogQL queries, and integrate with Grafana for visualization. Use when implementing lightweight log aggregation, especially in Kubernetes environments.

日本語の概要は準備中です。原文の説明を表示しています。

Use when installing skills from a shared ai-agent-skills library repo. Inspect with `--list` first, prefer `--collection`, and preview with `--dry-run` before installing.

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Amazon brand protection toolkit. Detect hijackers, counterfeits, and unauthorized sellers. Includes MAP violation monitoring, trademark abuse detection, complaint templates for Brand Registry, and test buy evidence collection guides. No API key required.

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High-converting landing pages — campaign pages, collection pages, seasonal promos, A/B testing

日本語の概要は準備中です。原文の説明を表示しています。

Tax setup and compliance — sales tax, VAT, duty collection, tax-exempt customers, reporting

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Audit and optimize e-commerce landing pages for conversion. CTA placement, trust signals, page structure, copy optimization, and A/B testing strategy for product pages, collection pages, and campaign landing pages.

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CloudBase PostgreSQL access-pattern and slow-query quality guidance. Use when designing how tables are read and written, eliminating per-row database calls, adding indexes for filters or joins, reviewing high-traffic data access, or explaining a slow SQL query. Not for first-time PG SDK setup, login UI, or NoSQL collections.

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Design, improve, and evaluate reusable agent skills with high-quality SKILL.md files, precise trigger descriptions, progressive disclosure, and testable behavior. This skill should be used when users ask to create a new skill, rewrite or review an existing skill, audit a skill collection such as `config/source/skills` for redundancy or overlap, improve skill trigger quality, organize skill references, or evaluate whether a skill should trigger and behave correctly.

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Use CloudBase document database Web SDK only for confirmed NoSQL collection work. Query, create, update, and delete document data; if the task mentions PostgreSQL / CloudBase PG / app.rdb(), route to postgresql-development instead.

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Configure and troubleshoot CCAM Remote Data Sources that collect Claude Code and Codex history over SSH. Use when adding, editing, testing, syncing, or removing a remote machine, verifying provider paths, or deciding whether to retain or purge imported sessions.

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Create and manage Shopify products via the Admin GraphQL API or CSV import. Workflow: gather data, choose method, execute, verify. Use whenever the user wants to add products to Shopify, bulk-import a catalog from CSV/spreadsheet/URL, update variants or prices, manage inventory quantities, upload product images, or assign products to collections.

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Use when a YouTube playlist is involved: pasted playlist links or IDs, requests to list playlist videos, browse playlist contents, or work through a playlist for transcripts or research. Also use when the user wants all videos from a series, course, or collection. Not for creating playlists or account management.

日本語の概要は準備中です。原文の説明を表示しています。

Pre-built animated React component collections combining Magic UI (150+ TypeScript/Tailwind/Motion components) and React Bits (90+ minimal-dependency animated components). Use this skill when building landing pages, marketing sites, dashboards, or interactive UIs requiring pre-made animated components instead of hand-crafting animations. Triggers on tasks involving animated UI components, Magic UI, React Bits, shadcn/ui integration, Tailwind CSS components, or component library selection. Alternative to manually implementing animations with Framer Motion or GSAP.

日本語の概要は準備中です。原文の説明を表示しています。