494 件 ・ 関連度順
概要と使いどころ
Bulk RNA-seq DE with PyDESeq2: load counts, normalize, fit negative binomial models, Wald test (BH-FDR), LFC shrinkage, volcano/MA plots. Use for two-group comparisons, multi-factor designs with batch correction, multiple contrasts.
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NCBI GEO access via GEOparse and E-utilities. Search by keyword/organism/platform, download GSE series matrices, parse GPL annotations, extract GSM metadata, load expression matrices into pandas. For single-cell use cellxgene-census; for multi-DB access use gget-genomic-databases.
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Fast in-memory DataFrame with lazy evaluation, parallel execution, Arrow backend. Use for tabular data in RAM (1–100 GB) when pandas is too slow. Expression API: select, filter, group_by, joins, pivots, window. Lazy mode enables predicate/projection pushdown. Reads CSV, Parquet, JSON, Excel, DBs, cloud. Larger-than-RAM: Dask; GPU: cuDF.
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GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.
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Interactive scientific visualization with Plotly. Two APIs: plotly.express (px) for one-liner DataFrame plots, plotly.graph_objects (go) for trace-level control. 40+ chart types with hover, zoom, pan, animation. Exports HTML or static PNG/SVG/PDF via kaleido. Use for volcano plots with gene hover, dose-response dashboards, expression heatmaps, 3D molecular views. Use seaborn for stats; matplotlib for publication figures.
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omics-plotting: publication-style figure authoring for omics / bioinformatics results with matplotlib / seaborn. Read this before writing any plotting or figure code in any omics analysis — RNA-seq, proteomics, single-cell, variant, or database results — not only when a plot is explicitly requested: whenever an analysis will produce a figure, load this first and follow its recipes. Covers volcano, MA, expression / correlation heatmap, GSEA bar / dot plot, box / violin / bar / ridgeline, PCA / UMAP / t-SNE scatter, Kaplan–Meier, Manhattan / QQ / forest. Supplies a shared journal-ready style and copy-paste recipes so every figure looks like one consistent system. To combine several plots into ONE multi-panel composite figure, use the sibling `multipanel` skill.
日本語の概要は準備中です。原文の説明を表示しています。
Provides patterns for unit testing Spring `@Scheduled` and `@Async` methods using JUnit 5, CompletableFuture, Awaitility, and Mockito. Covers mocking task execution and timing, verifying execution counts, testing cron expressions, validating retry behavior, and simulating thread pool behavior. Use when testing background tasks, cron jobs, periodic execution, scheduled tasks, or thread pool behavior.
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Provides patterns for unit testing Spring Cache annotations (@Cacheable, @CachePut, @CacheEvict). Generates test code that mocks cache managers, verifies cache hit/miss behavior, tests cache key generation with SpEL expressions, validates eviction strategies, and checks conditional caching scenarios. Triggers: caching tests, test Spring cache, mock cache, Spring Boot caching, cache hit/miss verification, @Cacheable testing.
日本語の概要は準備中です。原文の説明を表示しています。
Debug regex patterns with visual breakdowns, plain English explanations, test case generation, and flavor conversion. Use when user needs help with regular expressions or pattern matching.
日本語の概要は準備中です。原文の説明を表示しています。
Writes, explains, debugs, and optimizes BI calculations - Power BI / Fabric DAX measures and calculated columns, Tableau calculated fields (FIXED/INCLUDE/EXCLUDE LOD expressions, table calculations), and Looker LookML measures, dimensions, and derived tables. Use it whenever the request involves DAX, CALCULATE, a Power BI measure, a Tableau calc or LOD, LookML, or a business metric such as YoY, YTD, rolling 12 months, running total, percent of total, distinct customers, ranking, new vs returning customers, closing balances, or basket analysis. Use it especially when someone says a measure "shows the wrong total", "is blank", "ignores my slicer/filter", "repeats the same value on every row", or "is slow" - those are filter context, context transition, LOD order-of-operations, or fanout bugs this skill is built to diagnose. Produces the formula, the context it evaluates in, and a hand-checkable test with expected numbers.
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Routes DataChain operating guidance for Python SDK pipelines, query expressions, CLI and Studio commands, agent-harness knowledge workflows, and repository maintenance.
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Generate/create/write PromQL queries, metric expressions, alerting rules, recording rules, Prometheus dashboards.
日本語の概要は準備中です。原文の説明を表示しています。
Mathematical visualization skill for equations, proofs, and geometric concepts. **Triggers when:** - User mentions equations, formulas, or mathematical expressions - Request involves mathematical proofs or derivations - Content includes geometric relationships - User mentions LaTeX, calculus, algebra, geometry, trigonometry - Patterns: "equation", "formula", "prove", "derive", "graph", "plot" **Capabilities:** - LaTeX equation rendering with color-coded components - Function graphing and transformations - Geometric constructions and proofs - 3D mathematical surfaces - Step-by-step derivations with highlights
日本語の概要は準備中です。原文の説明を表示しています。
AAA character modeling for human anatomy, stylization, facial topology, clothing, hair, and animation-ready meshes. Use for game characters, facial expressions, and production character assets in Blender via MCP.
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Create original short videos using the 微表情问候｜侧身发现到笑容回稳 Creative DNA for MiniMax H3 or Seedance 2.0. Use when the user wants this causal, camera, motion, rhythm, or payoff structure with new subjects and surfaces.
日本語の概要は準備中です。原文の説明を表示しています。
Cloudflare Cron Triggers for scheduled Workers execution. Use for periodic tasks, scheduled jobs, or encountering handler not found, invalid cron expression, timezone errors.
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Provider-independent character design and continuity direction for generated media. Use when an agent must create, preserve, revise, or QA a recurring character across AI-generated images, video clips, avatars, animation, comics, ads, product mascots, serialized social posts, or multi-shot campaigns; especially when building character bibles, reference packs, prompts, expression/pose ranges, costume/hair/makeup/prop continuity, identity and likeness safeguards, iteration plans, handoff notes, or continuity reviews.
日本語の概要は準備中です。原文の説明を表示しています。
Provider-independent performance direction for generated video, avatar/spokesperson clips, animation, ads, film scenes, social content, and voice-led media. Use when an agent must cast or direct synthetic performers, avatars, animated characters, talking heads, AI video characters, or voice performances; plan acting beats, objective/obstacle/action, blocking, gesture, eye-line, facial expression, body language, lip-sync, voice alignment, rehearsal prompts, iteration, continuity, consent, and performance QA.
日本語の概要は準備中です。原文の説明を表示しています。
Perform differential expression analysis using edgeR in R/Bioconductor. Use for analyzing RNA-seq count data with the quasi-likelihood F-test framework, creating DGEList objects, normalization, dispersion estimation, and statistical testing. Use when performing DE analysis with edgeR.
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Comprehensive variant filtering including GATK VQSR, hard filters, bcftools expressions, and quality metric interpretation for SNPs and indels. Use when filtering variants using GATK best practices.
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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.
日本語の概要は準備中です。原文の説明を表示しています。
Perform differential expression analysis using DESeq2 in R/Bioconductor. Use for analyzing RNA-seq count data, creating DESeqDataSet objects, running the DESeq workflow, and extracting results with log fold change shrinkage. Use when performing DE analysis with DESeq2.
日本語の概要は準備中です。原文の説明を表示しています。
Differential abundance and state analysis for cytometry data. Compare cell populations between conditions using statistical methods. Use when testing for significant changes in cell frequencies or marker expression between groups.
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Perform differential expression analysis of miRNAs between conditions using DESeq2 or edgeR with small RNA-specific considerations. Use when identifying miRNAs that change between treatment groups, disease states, or developmental stages.
日本語の概要は準備中です。原文の説明を表示しています。