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Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD-confounded signal under the Schmidt 2020 cis-MR framework, screening on-target adverse phenotypes pheWAS-style, or producing publication-grade STROBE-MR plus PP.H4 evidence for a target gene.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "最小再現環境を作って", "再現環境を構築して", "問題を切り分けたい", "パッケージの不具合か確認したい", "create a minimal reproduction", "isolate the issue", "build a repro environment", "reproduce this bug", "narrow down the cause", "is this a package bug or my code", "このPRの問題を再現して", "this commit broke something", or wants to determine whether a bug is caused by a package, the environment, or application code. Accepts PR URLs, commit hashes, or branch names as input.

This skill should be used when the user wants to "investigate a bug", "debug an issue", "figure out why something is happening", "find the root cause", "troubleshoot", "強い推論で調査", "仮説を立てて検証", "原因を特定", "バグの原因調査", "なぜ動かないか調べて", "問題を切り分け", "原因不明", "デバッグ", or mentions systematic hypothesis-driven debugging. NOTE: Use this for investigating UNKNOWN causes, not for validating design proposals (use devils-advocate for that).

2,592 curated AI system prompts from Claude, ChatGPT, Cursor, v0, Devin, Grok, and more.

日本語の概要は準備中です。原文の説明を表示しています。

Complete guide for ASP.NET Core Web API integration testing. Use when performing integration testing on Web API endpoints or validating ProblemDetails error format. Covers WebApplicationFactory, IExceptionHandler, Testcontainers multi-container orchestration, Flurl URL construction, and AwesomeAssertions HTTP validation. Keywords: webapi integration testing, WebApplicationFactory, asp.net core integration test, webapi integration test, IExceptionHandler, ProblemDetails, ValidationProblemDetails, AwesomeAssertions, Flurl, Respawn, Be201Created, Be400BadRequest, multi-container testing, Collection Fixture, global exception handling

日本語の概要は準備中です。原文の説明を表示しています。

Make a web app feel native on a phone — the small CSS and meta-tag fixes that separate "a website in a browser" from something that feels installed. Covers sticky hover states, tap highlight flashes, the 100vh bug, inputs that zoom the page, laggy taps, pull-to-refresh hijacking scroll, content under the notch, long-press selecting button text, carousels that scroll the wrong way, mismatched status bars, and the rule that you test on real hardware. Use when a web app is being built for or reviewed on mobile, when something "works in Chrome but feels wrong on my phone", when building a PWA, a bottom sheet, a carousel, a full-screen layout, or any touch interaction. For motion itself use animate; for React Native use animate-expo.

日本語の概要は準備中です。原文の説明を表示しています。

Generate clean, minimal technical SVG diagrams in a consistent Cloudflare-inspired style. Use when creating architecture diagrams, flow diagrams, or component diagrams for blog posts and documentation.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks for "browser tests", "playwright tests", "end-to-end testing", "test user flows", "E2E coverage", "integration tests for UI", "page object pattern", "/e2e command", or discusses automated browser testing. Covers the E2E test loop workflow, Playwright patterns, page objects, and selector strategies.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "plan a feature", "create PRD", "interview me about requirements", "define stories", "write a spec", "break down feature into tasks", "create implementation plan", "help me scope this feature", "what questions should I answer", or discusses feature planning. Covers the PRD interview process, spec structure, story atomization, and 4-phase workflow from idea to Dex tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Manage git worktrees using a centralized worktrees folder. Use for parallel development, PR reviews, or isolated work.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks about "parallel agents", "background tasks", "run_in_background", "non-blocking agents", "check agent progress", "TaskOutput", "retrieve agent results", or discusses running multiple agents concurrently. Covers patterns for launching agents in background, monitoring progress, and retrieving results.

日本語の概要は準備中です。原文の説明を表示しています。

Transform brain dumps into polished blog posts in Nick Nisi's voice. Use when the user wants to write a blog post with scattered ideas, talking points, and conclusions that need organization into a cohesive narrative with Nick's conversational, authentic, and thoughtful tone.

日本語の概要は準備中です。原文の説明を表示しています。

Creates and manages Biome GritQL custom lint rules to enforce coding patterns. Use when creating linter rules, enforcing code conventions, preventing anti-patterns, or when the user mentions Biome, GritQL, custom lint rules, or AST-based linting.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "improve test coverage", "add unit tests", "TDD", "test this module", "write tests for", "increase coverage", "/ut command", or discusses unit testing strategies. Covers the unit test loop workflow, React Testing Library best practices, query priorities, and coverage improvement strategies.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when implementing features from a PRD spec, tracking implementation progress, or resuming work across sessions. Covers Dex task management for PRD story execution, daily workflows, and skill auto-loading.

日本語の概要は準備中です。原文の説明を表示しています。

Requires OFOX_API_KEY — create one at https://app.ofox.ai. Generate cheap vertical 9:16 drafts in one priced batch, pick a winner off the contact sheet, then re-render only that one. The cheap tier is the point — several times cheaper per second, so a whole set can cost less than one flagship clip. Use when a user wants Shorts/Reels/TikTok raw material rather than one finished video, e.g. "give me 5 vertical clips to choose from", "a few Reels drafts for this product", "some cheap options before we commit", or "batch me some 9:16 takes". Do not use when one finished clip is wanted — go straight to the scenario skill (seedance-ad-creative, ugc-ads, seedance-short-drama, seedance-product-video), which is also where this skill gets the prompt it drafts.

日本語の概要は準備中です。原文の説明を表示しています。

Calculate TAM, SAM, and SOM for new market segments using top-down and bottom-up methods

日本語の概要は準備中です。原文の説明を表示しています。

直前の説明が分かりにくかったときに、背景を補って説明し直します。簡略化された技術英語の規格とプロジェクトの用語集に沿い、話の流れを伝え直すスキルです。

• 直前の説明を分かりやすく聞き直したいとき
• 話の流れを理解するための背景説明
• プロジェクトの共通用語での説明

再現しにくい不具合や処理速度の悪化を、症状を判定するテストやスクリプトで調べます。原因候補の検証から修正、再発防止の確認まで進めるスキル。

• 再現しにくいエラーを調べたいとき
• 処理が遅くなった原因の調査
• 断続的な不具合を繰り返し検証

ローカルにある複数のAI開発エージェントのログを集計し、トークン数やAPI換算費用をSVGカードにします。READMEや資料に載せる利用状況をまとめられます。

• READMEにエージェント利用状況を掲載
• 複数エージェントの活動を共有したいとき
• トークン数とAPI換算費用の可視化

認証や決済、APIの実装時に、入力検証・アクセス権限・秘密情報の管理などを点検し、実装例と公開前のチェックリストで脆弱性対策を支えるスキル。

• ログインとアクセス権限の確認
• API入力とファイル投稿の点検
• 秘密情報や機密ログの見直し

参考動画の色調とカットの長さを測定し、再利用できるスタイル素材にまとめるスキル。色変換用のLUT、静止画、重ね合わせ素材、生成モデル向けの仕様を作ります。

• 参考動画の色調を素材化したいとき
• 似たテンポのためにカット間隔を測る
• ジャンル別のスタイル素材集づくり

処理の高速化を、現状の計測、仮説ごとの変更案の比較、正しさの検証へ分解し、時間や費用の上限内で最も速い安全な案と再実行できる手順を残すスキル。

• 遅い処理を計測しながら高速化したいとき
• 同じ入力条件で実装案を比較したいとき
• 応答時間・処理量・実行費用の評価