1.7万 件 ・ 関連度順
概要と使いどころ
Generates guidance for reliability, resilience, availability, redundancy, fault-tolerance, and disaster recovery (DR) for Google Cloud workloads based on the design principles and recommendations in the Google Cloud Well-Architected Framework. Use when the user asks to evaluate, design, or improve the reliability, resilience, availability, or disaster recovery capabilities of Google Cloud workloads.
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Provides data-retrieval best practices, tool selection guidance, and performant SQL query syntax for BigQuery telemetry across INFORMATION_SCHEMA, Cloud Monitoring, and the REST API. Use when the telemetry to fetch is already known, selecting telemetry tools, writing performant INFORMATION_SCHEMA queries, retrieving telemetry for diagnosing single-job performance bottlenecks, investigating slot contention, job concurrency and queue latency, analyzing reservation capacity, utilization and autoscaling saturation, or auditing capacity-based and on-demand compute and storage resource billable usage. Don't use for root-cause diagnosis or symptom troubleshooting when the cause is unknown (use bigquery-troubleshooting first), or for writing or optimizing business logic SQL (use bigquery-optimization).
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Leverages BigQuery's built-in machine learning and GenAI capabilities for advanced data analytics. Use when you need to write SQL queries that perform time-series forecasting, predict values, detect outliers or anomalies, find key drivers, perform semantic search or vector search, classify text, calculate similarity, summarize content, translate language, evaluate models, filter by semantic conditions, measure the causal effect of an intervention, compute correlations between columns, detect change points or structural breaks, extract trend or seasonality components, or leverage generative AI capabilities in BigQuery. Do not use for general BigQuery dataset, table, or job management requests.
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Configure and troubleshoot Salesforce Billing revenue recognition rules, schedules, and GL transaction generation under ASC 606. Triggers: 'revenue schedule not generated after order activation', 'blng__RevenueSchedule__c missing', 'blng__RevenueRecognitionRule__c on a product', 'Finance Periods not set up', 'performance obligation allocation for bundled products', 'distribution method', 'ASC 606 in Salesforce Billing'. NOT for billing schedules, invoice plans and invoice runs - use admin/billing-schedule-setup. NOT for invoice-to-payment mismatches at month-end close - use data/billing-data-reconciliation.
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Configure Dynamic Forms (field and section visibility on Lightning record pages) and Dynamic Actions (button and action visibility rules) in Lightning App Builder — enabling Dynamic Forms, converting page layout fields with the Upgrade Now wizard, writing field visibility rules (field value, profile, permission, record type, device), and controlling action bar visibility. NOT for page layout design or record type assignment — use admin/record-types-and-page-layouts. NOT for a full layout-to-Dynamic-Forms migration across record types or profiles — use admin/dynamic-forms-migration. Keywords: flexipage, fieldInstance, fieldItem, uiBehavior, visibilityRule, booleanFilter, UiFormulaCriterion, actionOverrides, profileActionOverrides, page activation, org default page, App Builder Upgrade Now.
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Audit web pages and components for WCAG 2.2 accessibility compliance. Use when a user asks to check accessibility, find a11y issues, audit for WCAG compliance, fix screen reader problems, check color contrast, ensure keyboard navigation works, or prepare for accessibility regulations like the European Accessibility Act or ADA.
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One page, automated tier — run the web accessibility (a11y) rule engine against a live page and locate every violation it can detect mechanically. Pass a URL, a config target name (e.g. `accesslint:accessibility-scan dev`), or nothing to use the default target from `accesslint.config.json`. Ensures a debuggable Chrome, runs the @accesslint/core engine over CDP, and returns a worklist of live-DOM WCAG 2.2 violations, each grounded to its DOM selector and source `file:line`. Locates; doesn't edit. Use it for 'is this page accessible', 'check a11y on this URL', 'find contrast and alt-text issues', or to verify a UI change. For hands-on keyboard and screen-reader checks use `accessibility-inspect`; for a whole site or product use `accessibility-audit`; to diff against uncommitted changes or a branch use `accessibility-diff`.
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One page, hands-on manual tier — drive a live page through the web accessibility (a11y) checks a rule engine can't decide: keyboard operation and focus order, screen-reader names, roles and states from the accessibility tree, reflow and zoom, reduced motion, form errors, and target size. Grades each finding by evidence basis (verified / confirm-with-a-human / human-required) and severity, and closes every criterion in a ledger: verified, flagged, not exercised, or N/A. Locates and assesses; does not fix (use `accessibility-fix`). Use it for keyboard testing, focus-order checks, screen-reader or a11y-tree review, reflow and zoom at 200%, or 'is this operable, not just lint-clean'. The automated tier is `accessibility-scan`; `accessibility-audit` runs both across a sampled site.
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Resolve CodeRabbit review feedback on a GitHub pull request. Collects every open CodeRabbit finding (inline threads, plus the nitpick and outside-diff findings packed into review bodies), judges and fixes each one against the real code with subagents, unifies fixes that share a pattern, commits locally, asks before pushing, then shows every reply draft linked to its finding and posts only on approval. Runs only on top-tier models. Use on "resolve the CodeRabbit feedback", "address coderabbit comments", "answer the rabbit", "fix what CodeRabbit flagged on
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Drafts a U.S. ocean Bill of Lading (B/L) functioning as receipt, contract of carriage, and document of title under COGSA or Hague-Visby. Covers negotiable and straight B/Ls, cargo description, freight allocation, and core carriage clauses. Use when drafting or reviewing a bill of lading, master/house B/L, ocean shipment documentation, or title transfer. Trigger keywords: bill of lading, B/L, ocean carriage, COGSA, Hague-Visby, negotiable, straight, master bill, house bill.
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Heart rate variability biometrics and emotional awareness training. Expert in HRV analysis, interoception training, biofeedback, and emotional intelligence. Activate on 'HRV', 'heart rate variability', 'alexithymia', 'biofeedback', 'vagal tone', 'interoception', 'RMSSD', 'autonomic nervous system'. NOT for general fitness tracking without HRV focus, simple heart rate monitoring, or diagnosing medical conditions (only licensed professionals diagnose).
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CEO/founder-mode plan review. Rethink the problem, find the 10-star product, challenge premises, expand scope when it creates a better product. Four modes: SCOPE EXPANSION (dream big), SELECTIVE EXPANSION (hold scope + cherry-pick expansions), HOLD SCOPE (maximum rigor), SCOPE REDUCTION (strip to essentials). Use when asked to "think bigger", "expand scope", "strategy review", "rethink this", or "is this ambitious enough". Proactively suggest when the user is questioning scope or ambition of a plan, or when the plan feels like it could be thinking bigger. Use AFTER a plan exists. For validating the idea itself before planning, use /mk:office-hours first.
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Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.
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Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.
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Estimates SNP heritability and partitions it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.
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Segments the genome into chromatin states from combinatorial histone modification and chromatin factor ChIP-seq data. Uses ChromHMM (multivariate HMM on binarized signal, v1.27), Segway (Dynamic Bayesian Network on continuous signal), EpiSegMix (flexible-distribution HMM with duration modeling, 2024), EpiLogos (multi-biosample visualization), IDEAS (cell-type-aware joint), and full-stack ChromHMM (Vu Ernst 2022) for cross-cell-type segmentations. Handles state-count selection (15 vs 18 vs 25 states), binarization choice, OverlapEnrichment / NeighborhoodEnrichment downstream analysis, and cross-biosample integration. Use when learning chromatin states from a histone mark panel, characterizing learned states by genomic feature enrichment, or comparing chromatin landscapes across cell types.
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Use this skill when working with Brain Imaging Data Structure (BIDS) datasets: organizing neuroscience and biomedical data (MRI, EEG, MEG, iEEG, PET, microscopy, NIRS, motion capture, EMG, MR spectroscopy, behavioral), querying BIDS layouts, validating compliance, converting DICOM to BIDS, writing metadata sidecars, or creating BIDS derivatives.
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This skill recommends bilateral adrenalectomy for patients with Cushing's syndrome when bilateral adrenal pathology is confirmed as the source of hypercortisolism. Clinical triggers include bilateral macronodular adrenal hyperplasia (BMAH), bilateral adrenal adenomas, or bilateral adrenal carcinoma identified by imaging.
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Expert-level computational biology covering molecular dynamics simulation, protein structure prediction, systems biology, network analysis, and machine learning in biology.
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Expert-level bioinformatics covering sequence analysis, structural bioinformatics, database searching, phylogenetic analysis, NGS data processing, single-cell analysis, and machine learning in biology.
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Expert-level probability theory knowledge. Use when working with probability spaces, random variables, distributions, expectation, variance, conditional probability, stochastic processes, Markov chains, martingales, or measure-theoretic probability. Also use when the user mentions 'sample space', 'random variable', 'expected value', 'variance', 'conditional probability', 'independence', 'Markov chain', 'Poisson process', 'moment generating function', 'law of large numbers', 'central limit theorem', or 'stochastic process'.
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Orientação de liderança técnica para equipes de engenharia, decisões de arquitetura e estratégia de tecnologia. Inclui analisador de débito técnico, calculadora de escalabilidade de equipes, frameworks de métricas de engenharia, ferramentas de avaliação de tecnologia e templates de ADR. Use ao avaliar débito técnico, escalar equipes de engenharia, avaliar tecnologias, tomar decisões de arquitetura, estabelecer métricas de engenharia ou quando o usuário menciona CTO, débito técnico, débito técnico, escalabilidade de equipes, decisões de arquitetura, avaliação de tecnologia, métricas de engenharia, métricas DORA ou estratégia de tecnologia.
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Load this skill immediately whenever a project contains an ACCESSIBILITY.md file, or whenever you are contributing to the mgifford/ACCESSIBILITY.md repository. Absolutely always read ACCESSIBILITY.md before proposing or writing any changes. Under no circumstances skip this skill when an ACCESSIBILITY.md file is present. This skill governs when and how all other accessibility topic skills must be loaded.
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