「signing」の検索結果

Create or update AgentSkills. Use when designing, structuring, or packaging skills with scripts, references, and assets.

日本語の概要は準備中です。原文の説明を表示しています。

Taxonomic classification of ASVs using reference databases like SILVA, GTDB, or UNITE. Covers naive Bayes classifiers (DADA2, IDTAXA) and exact matching approaches. Use when assigning taxonomy to ASVs after DADA2 amplicon processing.

日本語の概要は準備中です。原文の説明を表示しています。

Metabolite identification from m/z and retention time. Covers database matching, MS/MS spectral matching, and confidence level assignment. Use when assigning compound identities to detected features in untargeted metabolomics.

日本語の概要は準備中です。原文の説明を表示しています。

Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens. Use when designing vaccines, mapping antibody binding sites, or predicting immunogenic peptides.

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Cell type assignment from marker expression in IMC data. Covers manual gating, clustering, and automated classification approaches. Use when assigning cell types to segmented IMC cells based on protein marker expression or when phenotyping cells in multiplexed imaging data.

日本語の概要は準備中です。原文の説明を表示しています。

Design guide RNAs for CRISPR-Cas9/Cas12a experiments using CRISPRscan and local scoring algorithms. Score guides for on-target activity using Rule Set 2 and Azimuth models. Use when designing sgRNAs for gene knockout, activation, or repression experiments.

日本語の概要は準備中です。原文の説明を表示しています。

Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Select optimal positions for C-to-T or A-to-G conversions without double-strand breaks. Use when designing base editor experiments for precise nucleotide changes.

日本語の概要は準備中です。原文の説明を表示しています。

CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering. Use when designing custom sgRNA libraries for knockout, activation, or interference screens.

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Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms. Use when designing donor templates for precise insertions, tagging, or allele replacement.

日本語の概要は準備中です。原文の説明を表示しています。

Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.

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End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.

日本語の概要は準備中です。原文の説明を表示しています。

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

日本語の概要は準備中です。原文の説明を表示しています。

Apply Eric Evans-inspired DDD rules when modeling a complex domain, defining bounded contexts, protecting ubiquitous language, or designing aggregates.

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Apply Michael T. Nygard-inspired production reliability rules when designing failure handling, timeouts, retries, circuit breakers, observability, or deployment behavior.

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Apply John Ousterhout-inspired software design rules when reducing complexity, designing module boundaries, or reviewing APIs and abstractions.

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Use when the user asks to "audit an email program" or "is this campaign safe to send"; runs a typed 20-item SEND profile with authentication, consent, opt-out, and claim veto checks on own evidence. Not for building deliverability setup — use deliverability-qa; not for designing lifecycle flows — use email-sequence-designer. 邮件质量审计/EQS评分/发送前放行

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Use when the user asks to "pre-launch check the landing page", "run a Quality-Score preflight", or "verify ad-to-page message match before launch"; produces an ad↔page continuity report — message-match gaps, above-the-fold check, page-speed read, form-friction count, mobile-render flags — as a pass/fix punch list. Not for redesigning or rewriting the page — use landing-optimizer; not for scoring the account or the RQS — use ad-account-auditor. 落地页体验预检/广告落地页一致性检查

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Apply the Zeigarnik Effect — incomplete tasks stay mentally active. Use when designing progress indicators, saved drafts, and return hooks. For the emotional shape of the ending, use `peak-end-rule`.

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Apply the Law of Continuity — the eye follows alignment and unbroken paths. Use when sequencing steps, aligning content, or designing carousels and timelines. For grouping rather than sequencing, use `law-of-proximity`.

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Apply the Law of Figure-Ground — establish which layer is foreground and actionable versus background. Use when designing modals, overlays, and depth. For emphasising one element among peers, use `von-restorff-effect`.

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Apply the Peak-End Rule — a flow is remembered by its most intense moment and its last. Use when designing completion, celebration, or cancellation moments. For sustaining engagement mid-flow, use `zeigarnik-effect`.

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Connects AI agents to remote Windows desktop applications on Amazon WorkSpaces Applications (AppStream 2.0) through the managed Agent Access MCP server, and guides reliable desktop automation. Covers connecting an agent to the MCP endpoint (SigV4, streaming URL, and Active Directory SAML/Domain Join), BLOCKING vs POLLING connect modes, the computer-use tools (screenshot, click, type, key, scroll), screenshot-budget and action-batching discipline, MCP tool forwarding (forwarded___ tools), session lifecycle and expire-on-delete, and troubleshooting connection errors. Use when building or debugging an agent that drives a remote Windows desktop or GUI application via WorkSpaces Applications / AppStream — including "dcv session not ready", "client_disconnected", 400 signing-region, POLLING/connection_status, SAML assertion, or forwarded tool questions. Not for Amazon WorkSpaces Personal/Core virtual desktops or general AppStream fleet administration unrelated to agent access.

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Gets AWS credentials for CLI/SDK access via `aws login`. Activates when a developer needs to authenticate to AWS for local development, when an AWS operation fails due to missing or expired credentials, or when someone asks about setting up AWS access. Triggers: "set up AWS", "configure AWS", "aws login", "get credentials", "authenticate", "session expired", "token expired", "no credentials", "AccessDeniedException" with no configured credentials.

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Designs, reviews, and debugs DynamoDB data layers from design axioms — enumerates access patterns, chooses partition/sort keys and GSIs, decides single-table vs. multi-table, configures Streams, Global Tables, TTL, vector indexes for similarity search, and zero-ETL integrations to OpenSearch/Redshift/SageMaker Lakehouse, and produces a defensible data-layer design with a monthly cost estimate and optional live validation. Applies whenever a user is designing, reviewing, or refactoring anything backed by DynamoDB — schemas, access patterns, GSIs, single- vs. multi-table choices, Streams consumers, transactional outboxes, Global Tables, zero-ETL pipelines, or storing embeddings and running semantic/vector similarity search with SearchVectors on items already in DynamoDB — even when they don't say "axioms" or "design review." Also applies when debugging hot partitions, throttling, unbounded Scans, LWW conflicts, or surprise bills on DynamoDB workloads.

日本語の概要は準備中です。原文の説明を表示しています。