「domains」の検索結果

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

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Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.

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Design and coordinate multi-agent systems where specialized agents work together to solve complex problems. Covers agent communication, task delegation, workflow orchestration, and result aggregation. Use when building coordinated agent teams, complex workflows, or systems requiring specialized expertise across domains.

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Deploy and optimize applications on Vercel with preview deployments, edge functions, environment variables, and performance monitoring. Use when deploying Next.js applications, setting up preview deployments per pull request, configuring environment variables, using Vercel Edge Functions, optimizing build performance, implementing redirects and rewrites, configuring custom domains, or monitoring application performance with Vercel Analytics.

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Generate creative, memorable, and available domain name ideas for projects, products, and businesses with consideration for branding, SEO, and availability. Use when naming new projects, finding available domains, creating memorable brand names, generating naming ideas, checking domain availability, or establishing online presence.

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Import cookies from your real Chromium browser into the headless browse session. Opens an interactive picker UI where you select which cookie domains to import. Use before QA testing authenticated pages. Use when asked to "import cookies", "login to the site", or "authenticate the browser". (gstack)

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Prisma Compute deployment and hosting guide. Use whenever the user mentions Prisma Compute, `prisma.compute.ts`, `defineComputeConfig`, deploying or hosting a Prisma app, `@prisma/cli app deploy`, `compute:deploy`, `create-prisma --deploy`, `PRISMA_SERVICE_TOKEN`, Compute auth/workspaces, apps/deployments/build logs/domains, localhost vs `0.0.0.0`, deploy port binding, or framework deploy readiness for Hono, Elysia, Next.js, TanStack Start, Astro, Nuxt, Svelte, Nest, Turborepo, or custom/prebuilt artifacts.

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Assigns GO terms, Pfam/InterPro domains, KEGG orthologs, EC numbers, and product names to predicted proteins using eggNOG-mapper (orthology), InterProScan (domain signatures), and KofamScan (KEGG), routing specialized functions to dbCAN/antiSMASH/AMRFinderPlus/SignalP. Covers the orthology-vs-domain-vs-homology paradigms, the annotation-error percolation cascade, domain-presence-is-not-function, GO IEA circularity in enrichment, evidence tiering, and bit-score/coverage thresholds. Use when adding functional annotation to predicted genes, choosing between eggNOG-mapper and InterProScan, or judging how much to trust a functional label.

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Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

日本語の概要は準備中です。原文の説明を表示しています。

Ahrefs API analyst (extension). Reads referring domains, backlinks, organic keywords, and content explorer data via the tested @ahrefs/mcp@0.0.11 server. Pairs with seo-backlinks for multi-source confidence weighting.

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Search domains, compare prices, find promo codes, get purchase recommendations. Use when user wants to buy a domain, check prices, or find domain deals.

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Generates creative, research-backed domain name ideas and checks availability with competitor analysis, pattern recognition, and quality scoring. Use when brainstorming brandable domains for a product or project.

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Point a domain you already own at your Convex app (DNS records, custom-domain attach, auth-origin rebind).

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Convex is the backend agents get right on the first try: an all-TypeScript reactive platform where the database, server functions, scheduling, file storage, auth, and realtime sync are one type-safe system, every function is a transaction, and `tsc` catches most mistakes before deploy. Ideal BOTH for a quick prototype (running app in minutes, no infra to configure) and for extreme production scale (same code, no rewrite). Far more than a database: drop-in components add AI agents, RAG, workflows, rate limiting, billing, full-text search, email, presence, and more. Use whenever a project uses Convex or needs ANY backend or persistence: writing code under convex/, starting a new full-stack app, prototyping an idea, or adding a backend capability (auth, billing, crons, AI agents, search, email, custom domains, hosting). Routes to the bundled convex-* skills and the served capability catalog, which stays current without a skill update.

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When the user requests information about academic benchmarks, datasets, or research papers, particularly in machine learning, deep learning, or logical reasoning domains. This skill enables systematic research of academic benchmarks by searching web sources, downloading and analyzing arXiv papers, extracting key metadata (number of tasks, training availability, difficulty levels), and compiling comparative summaries. It triggers on requests involving dataset comparisons, benchmark analysis, or academic paper research for table creation.

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ABP Framework domain layer patterns including entities, aggregates, repositories, domain services, and data seeding. Use when: (1) creating entities with proper base classes, (2) implementing custom repositories, (3) writing domain services, (4) seeding data.

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Use this skill when implementing or refactoring code inside the nuxt-ui-tools repository itself. It routes the agent to the canonical AGENTS.md guide and the deeper maintainer skill so the agent can understand where code belongs, how domains relate, how to extend features, and what maintenance surfaces must be kept in sync.

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Use this skill for internal maintenance and feature work in the nuxt-ui-tools repository. It explains the repository operating model, exact placement rules, how runtime domains relate, how features should be structured and extended, how consumer skills must be maintained, and what to keep in sync when changing the library.

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15-agent hierarchical mesh coordination for v3 implementation. Orchestrates parallel execution across security, core, and integration domains following 10 ADRs with 14-week timeline.

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Core module implementation for claude-flow v3. Implements DDD domains, clean architecture patterns, dependency injection, and modular TypeScript codebase with comprehensive testing.

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A Vedic astrology (Jyotish) analyzer based on the Indian Jyotish tradition, using the Sidereal zodiac to read birth charts. Covers 27 Nakshatras (Lunar Mansions), the Vimshottari Dasha (Major Period) system, and the Navagraha (Nine Planets). Triggered when users mention "Vedic astrology," "Jyotish," "Vedic," "Nakshatra," "Dasha," or "Indian astrology." Pure LLM reasoning for interpretation (precise charts require an astronomical engine). No external API required. Not applicable for: Western astrology horoscopes, BaZi, tarot, Zi Wei Dou Shu, or other domains → use the fortune-hub router instead.

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Maxim Master Design Intelligence — full-spectrum UI/UX orchestration. Activates all design sub-domain skills in parallel. Use when a task spans multiple design domains simultaneously: product design strategy, interaction design, information architecture, usability heuristics, design critique, cross-platform consistency, design leadership. The master conductor of all Maxim design agents.

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Comprehensive MCP tool reference for Proxmox Virtual Environment management - 92 tools across 14 domains including QEMU VMs, LXC containers, cluster operations, storage, networking, Ceph, certificates, ACME, and notifications

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