「confidence」の検索結果

Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.

日本語の概要は準備中です。原文の説明を表示しています。

Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

日本語の概要は準備中です。原文の説明を表示しています。

Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

日本語の概要は準備中です。原文の説明を表示しています。

Reflection-first problem solving methodology for Convex development. Use before implementing any solution to ensure proper root cause analysis, 98% code confidence, and minimal change scope.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze a completed phase diff for high-confidence behavior-preserving simplifications and apply only explicitly approved proposals. Use after execution and before review to reduce duplication, dead code, needless complexity, or avoidable inefficiency.

日本語の概要は準備中です。原文の説明を表示しています。

Write comprehensive end-to-end tests that verify complete user workflows, integration between components, and system behavior from user perspective using Playwright, Cypress, or similar frameworks. Use when testing user flows, verifying feature integration, testing across real browsers, ensuring UI interactions work correctly, validating form submissions end-to-end, testing authentication flows, catching regressions, automating QA processes, testing API integrations, or building confidence in production deployments.

日本語の概要は準備中です。原文の説明を表示しています。

Chief Security Officer mode. Infrastructure-first security audit: secrets archaeology, dependency supply chain, CI/CD pipeline security, LLM/AI security, skill supply chain scanning, plus OWASP Top 10, STRIDE threat modeling, and active verification. Two modes: daily (zero-noise, 8/10 confidence gate) and comprehensive (monthly deep scan, 2/10 bar). Trend tracking across audit runs. Use when: "security audit", "threat model", "pentest review", "OWASP", "CSO review". (gstack) Voice triggers (speech-to-text aliases): "see-so", "see so", "security review", "security check", "vulnerability scan", "run security".

日本語の概要は準備中です。原文の説明を表示しています。

Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.

日本語の概要は準備中です。原文の説明を表示しています。

Query protein-protein and gene interaction databases (STRING, BioGRID, IntAct, SIGNOR, Reactome, HuRI, HuMAP, OmniPath, ConsensusPathDB, DIP). Use when building PPI networks, choosing between physical vs functional vs genetic interactions, signed/directed vs undirected, high-throughput vs curated, picking confidence thresholds, aggregating across resources, or navigating license constraints. Encodes the database decision matrix, STRING v12 channel semantics, OmniPath as meta-database, SIGNOR for signed signaling, and per-resource rate limits.

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Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. Use when orthologs are already curated upstream, when the question is "what is the X ortholog of Y" rather than "how to infer orthology de novo", when batch-mapping gene IDs across species, or when comparing the resources for consensus calls. Encodes confidence-level semantics, 1:1 vs 1:many vs many:many, HomoloGene deprecation, and when to defect to de novo computation.

日本語の概要は準備中です。原文の説明を表示しています。

Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

日本語の概要は準備中です。原文の説明を表示しています。

Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

日本語の概要は準備中です。原文の説明を表示しています。

Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

日本語の概要は準備中です。原文の説明を表示しています。

Ahrefs API analyst (extension). Reads referring domains, backlinks, organic keywords, and content explorer data via the tested @ahrefs/mcp@0.0.11 server. Pairs with seo-backlinks for multi-source confidence weighting.

日本語の概要は準備中です。原文の説明を表示しています。

Reflection-first problem solving methodology for Convex development. Use before implementing any solution to ensure proper root cause analysis, 98% code confidence, and minimal change scope.

日本語の概要は準備中です。原文の説明を表示しています。

Calculate statistical significance for A/B tests. Sample size estimation, power analysis, and conversion rate comparisons with confidence intervals.

日本語の概要は準備中です。原文の説明を表示しています。

[62] VALIDATE. Final self-check before delivery. Verify goal alignment, completeness, correctness, and identify residual risks. Produces quality score (0-100) and delivery status. Use when completing any significant work, before handoff, or when you need confidence that work is ready.

日本語の概要は準備中です。原文の説明を表示しています。

[23] UNDERSTAND. Consult external AI models when internal sources are exhausted. Build quality prompts using Prompt150 formula (Context + Query + Method + Style). Use when Loop150 exhausts internal sources, need real-world precedents, confidence <75%, or require reasoning from specialized AI models.

日本語の概要は準備中です。原文の説明を表示しています。

Decision framework for choosing between regex and LLM when parsing structured text — start with regex, add LLM only for low-confidence edge cases.

日本語の概要は準備中です。原文の説明を表示しています。

Instinct-based learning system that observes sessions via hooks, creates atomic instincts with confidence scoring, and evolves them into skills/commands/agents. v2.1 adds project-scoped instincts to prevent cross-project contamination.

日本語の概要は準備中です。原文の説明を表示しています。

Audit trail, confidence tagging, and ethical checks on every AI decision your operator produces.

日本語の概要は準備中です。原文の説明を表示しています。

Maxim 3D CGI product render — engineered for purchase confidence and premium positioning. Uses Material Realism + Endowment Effect + Photorealism Trust Signals to move premium-product viewers toward purchase. Use for luxury product reveals, architectural visualization, tech hardware marketing, high-ticket commerce.

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Atom of Thoughts (AoT) reasoning - decompose complex problems into atomic units with confidence tracking and backtracking. For genuinely complex reasoning, not everyday questions. Triggers on: atomise, complex reasoning, decompose problem, structured thinking, verify hypothesis.

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Human verification for AI agents. Submit claims, draft responses, or observation requests to human domain experts via the 2O API. Returns structured verdicts with confidence scores and evidence.

日本語の概要は準備中です。原文の説明を表示しています。