562 件 ・ 関連度順
概要と使いどころ
Orchestrate unattended resolution of open GitHub issues - triage by complexity, dispatch parallel worker agents into isolated worktrees, review their diffs, open PRs, and monitor CI and CodeRabbit until green. Use when asked to work through open issues autonomously or put Claude on auto-pilot.
日本語の概要は準備中です。原文の説明を表示しています。
Use when morphir-scala work needs environment diagnostics or build/network/sandbox unblocking; reference repository management; branch lifecycle refresh after squash-merging a target branch into main; Morphir IR spec/schema sync or export; or task-tracking configuration and beads mode resolution.
日本語の概要は準備中です。原文の説明を表示しています。
Improve image quality by enhancing resolution, sharpness, and clarity. Perfect for screenshots, documentation, presentations, and social media images.
日本語の概要は準備中です。原文の説明を表示しています。
Drafts a Certificate of Incumbency certifying current officers, directors, and signing authority for a U.S. corporation. Covers exact legal name matching, incumbency tables with specimen signatures, board resolution certification, authority limitations, reliance language, and execution formalities. Use when banks, lenders, investors, or counterparties require verification of corporate authority for closings, financings, or transactions.
日本語の概要は準備中です。原文の説明を表示しています。
Produces a structured, objective summary of corporate board meetings covering metadata, quorum, attendance, conflicts, resolutions with vote counts, committee reports, and significant corporate actions. Use when summarizing board minutes, creating a corporate governance record, or preparing a post-meeting recap for officers, shareholders, or regulators.
日本語の概要は準備中です。原文の説明を表示しています。
Drafts corporate board of directors meeting minutes. Triggers on "board minutes", "minutes of board meeting", "board of directors meeting minutes", "corporate minutes", "board resolutions", or "bylaws compliance".
日本語の概要は準備中です。原文の説明を表示しています。
Drafts Articles of Dissolution (Certificate of Dissolution) for U.S. corporations to terminate legal existence via state filing. Reviews articles of incorporation, bylaws, board resolutions, and shareholder consents for jurisdiction-specific compliance. Use when preparing dissolution filings, terminating a corporation, or drafting dissolution certificates for Secretary of State submission.
日本語の概要は準備中です。原文の説明を表示しています。
Drafts U.S. litigation attorney representation agreements for client onboarding, covering scope, fees, retainers, confidentiality, conflicts, duties, withdrawal, and dispute resolution. Use when converting consultations into enforceable engagement terms for civil litigation matters including personal injury. Trigger: engagement letter, litigation retainer, representation agreement, fee contract, conflict disclosure, attorney withdrawal, client acknowledgment.
日本語の概要は準備中です。原文の説明を表示しています。
Manages end-to-end workflow for multi-organization amicus coalition briefs in appellate courts. Covers single-pen drafting governance, position alignment, conflict resolution, documented sign-offs, FRAP 29/Rule 37.6 disclosures, FRAP 26.1 corporate disclosures, cover formatting for multiple amici, and compliant filing. Use when coordinating coalition amicus briefs, managing sign-offs, drafting joint friend-of-court briefs, handling multi-amici filing, or resolving inter-organization conflicts. Triggers on phrases like "coalition brief," "12 orgs joining this amicus," or "coordinate the amicus."
日本語の概要は準備中です。原文の説明を表示しています。
Generates structured summaries of mediation and arbitration proceedings, extracting outcomes, settlement terms, monetary amounts, obligations, releases, and enforcement steps. Trigger when the user needs to document mediation settlements, arbitration awards, or partial ADR resolutions from transcripts, agreements, mediator reports, or awards.
日本語の概要は準備中です。原文の説明を表示しています。
Resolve an in-progress git merge or rebase conflict end to end: read the conflict state, recover each side's original intent, resolve every hunk, run the project's checks, and prepare the merge/rebase for an explicitly approved finish. Use when asked to "resolve merge conflicts", "fix this rebase", "finish the merge", or when `git status` shows conflicted (unmerged) paths. NOT for the full ship pipeline that merges the base branch first (see mk:ship); NOT for debugging a runtime bug or test failure unrelated to a conflict (see mk:investigate / mk:fix).
日本語の概要は準備中です。原文の説明を表示しています。
Resolve a verified cluster of Rembric issues from causal root to evidence-gated closure. Use after systemic triage identifies a shared root, or when the user asks to attack issues at the root, create a mechanism map, plan a deletion-first fix, or close a fixed/stale issue cluster. Use `diagnose` for a single defect whose reproduction is not yet established.
日本語の概要は準備中です。原文の説明を表示しています。
Git branching strategies, conflict resolution, rebase workflows, monorepo patterns, and advanced operations like cherry-pick, bisect, and reflog recovery. Activate on "git", "branching strategy", "merge conflict", "rebase", "cherry-pick", "monorepo git", "git bisect", "git reflog", "squash commits". NOT for GitHub Actions CI/CD (use github-actions-pipeline-builder), GitHub API/webhooks, or PR review processes (use code-review-checklist).
日本語の概要は準備中です。原文の説明を表示しています。
Combines and synthesizes outputs from parallel DAG branches. Handles merge strategies, conflict resolution, and result formatting. Activate on 'aggregate results', 'combine outputs', 'merge branches', 'synthesize results', 'fan-in'. NOT for execution (use dag-parallel-executor) or scheduling (use dag-task-scheduler).
日本語の概要は準備中です。原文の説明を表示しています。
Apply normative BDI reasoning to agents that must detect norms, choose which commitments to internalize, and resolve conflicts by comparing consequences. Use when obligations, prohibitions, or policies collide in autonomous systems. NOT for simple fixed-priority rules, pure constraint satisfaction, or domains where no real normative conflict exists.
日本語の概要は準備中です。原文の説明を表示しています。
Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot; MetaPlotR; deepTools computeMatrix scale-regions), peak-centred heatmaps (ComplexHeatmap; deepTools plotHeatmap), IP-vs-input paired browser tracks (log2 IP/input bigWig via deepTools bamCompare; pyGenomeTracks; Gviz; IGV/UCSC track hubs), DRACH sequence-logo plots (ggseqlogo; MEME), feature-distribution stacked bars, and volcano/MA plots for differential modification. Establishes stop-codon enrichment in the metagene plot as the biological QC anchor for any MeRIP dataset (Dominissini 2012; Meyer 2012). Use when producing the canonical metagene plot with stop-codon enrichment as a QC anchor, building paired IP/input genome-browser tracks at single-locus resolution, plotting peak-centred heatmaps clustered by condition, summarising peak distribution across transcript features, generating DRACH motif logos as sanity checks, rendering volcano plots of differential m6A, or reproducing the stop-codon enrichment plot.
日本語の概要は準備中です。原文の説明を表示しています。
Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. Encodes Ensembl version stripping with GENCODE _PAR_Y preservation, the Ziemann 2016 Excel autocorrect debacle and Bruford 2020 HGNC renames (SEPT*->SEPTIN*, MARCH*->MARCHF*, MARC*->MTARC*, DEC1->DELEC1), OCT4/POU5F1 alias resolution, biomaRt archive endpoints for release pinning, the `filters` (plural) gotcha, MANE Select for clinical reporting, cross-species orthology via Ensembl Compara / OMA / OrthoDB, and tx2gene construction for tximport. Use when converting gene IDs across systems, handling renamed symbols, building tx2gene, pinning to a specific Ensembl release for reproducibility, or mapping cross-species orthologs.
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Assigns pathogen lineages (SARS-CoV-2 Pangolin UShER mode; Nextclade clade + QC; pango-designation alias resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage-fitness modelling (multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data and Nextclade dataset version pinning (mandatory; lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme churn (V3/V4/V4.1/V5.3.2/Midnight) with dropout regions, and recombinant X-prefix designation lag. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater into lineage frequencies with Freyja, tracking lineage frequencies over time, handling ARTIC primer dropouts, or running surveillance for SARS-CoV-2/influenza/Mpox/RSV/H5N1/measles.
日本語の概要は準備中です。原文の説明を表示しています。
Corrects fluorophore spillover (conventional compensation) or spectral overlap (spectral unmixing) and applies variance-stabilizing transforms (logicle/biexponential, arcsinh, log) for flow and mass cytometry. Covers spillover-matrix estimation from single-stain controls, AutoSpill, the spillover spreading matrix and why panel design (not compensation) bounds resolution, compensate-then-transform ordering, and arcsinh cofactor choice (5 for CyTOF, ~150 for fluorescence, per-channel via flowVS). Use when correcting spectral overlap, preparing data for gating/clustering, choosing logicle vs arcsinh, deciding a cofactor, or distinguishing compensation from spectral unmixing.
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Annotate CLIP-seq peaks or crosslink sites to RNA features (5'UTR, CDS, 3'UTR, intron, splice junction, snoRNA, tRNA, ncRNA, repeat elements) with ChIPseeker, RCAS, RBP-Maps (Yeo splicing regulatory maps), and bedtools, applying feature-priority hierarchies, transcript-context resolution, and metagene aggregation. Use when characterizing where in transcripts an RBP binds, comparing peak distribution across regions, generating splicing-regulatory maps relative to alternative-splicing events, or distinguishing exonic vs intronic vs UTR binding.
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Resolve subclonal copy number, whole-genome doubling, and copy-number tumor evolution from bulk sequencing with Battenberg, TITAN, and MEDICC2. Covers clonal versus subclonal copy-number states, haplotype phasing for subclonal resolution, cancer cell fraction, whole-genome-doubling detection and timing relative to mutations, mirrored subclonal allelic imbalance, and copy-number phylogenies. Use when a tumor is heterogeneous and bulk data shows non-integer copy number, when calling subclonal CNAs, detecting or timing whole-genome doubling, reconstructing copy-number evolution, or deciding between Battenberg and TITAN.
日本語の概要は準備中です。原文の説明を表示しています。
Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.
日本語の概要は準備中です。原文の説明を表示しています。
Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical conversion), DART-seq (Meyer 2019, APOBEC1-YTH fusion), m6Anet (nanopore direct RNA), or MeRIP-seq with calibration. Use when distinguishing antibody-based from antibody-free m6A detection methods, applying the DRACH motif constraint, reconciling cross-method disagreements (DART 44% in DRACH vs GLORI), or detecting m6Am at the cap.
日本語の概要は準備中です。原文の説明を表示しています。
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.
日本語の概要は準備中です。原文の説明を表示しています。