「gear」の検索結果

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

日本語の概要は準備中です。原文の説明を表示しています。

Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

日本語の概要は準備中です。原文の説明を表示しています。

Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.

日本語の概要は準備中です。原文の説明を表示しています。

Envie e receba mensagens criptograficamente assinadas entre agentes de IA usando o Agent Messaging Protocol (AMP). Use quando o usuário pedir para "enviar uma mensagem para um agente", "verificar caixa de entrada do agente", "mensagear outro agente", "responder a uma mensagem", "notificar um agente" ou qualquer tarefa de comunicação entre agentes.

日本語の概要は準備中です。原文の説明を表示しています。

TDD RGB(Red→Green→Blue) 사이클 진행 — 테스트 목록의 한 항목씩 tdd-red·tdd-green·tdd-blue 에이전트에 순차 위임하고 기어(low/mid/high)로 검토 밀도를 조절. "RGB 사이클 돌려", "다음 테스트 진행", "TDD 사이클 계속", "red-green-blue", "/tdd-rgb" 요청 시 사용. 단, feature 하나를 plan 합의 후 끝까지 자율 구현하는 것은 /tdd-feature, 계획 문서만 작성하는 것은 /tdd-plan이 적합. /tdd-rgb [plan-doc-path] [--gear=low|mid|high]로 호출.

日本語の概要は準備中です。原文の説明を表示しています。

Einmaliger Tasksolver+Writer+Maintainer-Durchlauf fuer den Projektordner, in dem die Session gerade sowieso gearbeitet hat (inkl. Unterordner) — kein systemweiter Sweep. Loest offene triviale/autonome Register-Punkte, aktualisiert Dokumentation auf den gemessenen Ist-Stand (im Projekt UND in der Root der Pipeline, in der das Projekt liegt) und raeumt Strays/Temp- Dateien nach dem Papierkorb-Prinzip weg. Nutze diesen Skill bei /tidy-up, "raeum das Projekt auf", "mach hier sauber bevor wir weitermachen", am Ende einer Arbeitssitzung an einem Projekt, oder als faellige autonome Aufgabe innerhalb von /work-autonomous + /goal.

日本語の概要は準備中です。原文の説明を表示しています。

Create, edit, or debug parametric 3D CAD parts in CadQuery (Python) that export to STEP for SolidWorks. Use when the request involves CadQuery, .step/.stl export, or modelling a physical part — enclosure, bracket, PCB, motor mount, cam, gear. Also use when a STEP will not open in CAD, or geometry looks correct in STL but is invalid as a solid. Applies a verification discipline before export and documented OCC pitfalls.

日本語の概要は準備中です。原文の説明を表示しています。

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

日本語の概要は準備中です。原文の説明を表示しています。

Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

日本語の概要は準備中です。原文の説明を表示しています。

Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.

日本語の概要は準備中です。原文の説明を表示しています。

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

日本語の概要は準備中です。原文の説明を表示しています。

Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.

日本語の概要は準備中です。原文の説明を表示しています。

Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

日本語の概要は準備中です。原文の説明を表示しています。

WPS (Wi-Fi Protected Setup) PIN attack methodology — Pixie Dust offline attack against vulnerable chipsets (Ralink, Realtek, Broadcom, MediaTek), online PIN brute-force with reaver/bully, lockout handling, time-of-day evasion, WPS push-button vulnerability windows, and PIN-to-PSK derivation. Use when a target SOHO router exposes WPS — common on consumer ISP gear, often left enabled by default even when WPS attacks have been known for over a decade.

日本語の概要は準備中です。原文の説明を表示しています。