「loops」の検索結果

End-to-end Hi-C analysis workflow from FASTQ to compartments, TADs, and loops, with the decision of WHICH features the sequencing depth can support. Covers pairtools read-pair processing and library QC, cooler matrices, ICE balancing and distance-decay expected, A/B compartments, TAD boundaries, loop calling, and the routing of HiChIP/PLAC-seq/Capture Hi-C to protein-directed loop callers. Use when processing Hi-C data end to end, deciding a resolution for a given depth, or choosing between bulk-Hi-C and protein-directed loop calling.

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Design AI feedback loops for continuous improvement. TRIGGERS - Use when user needs help with ai-feedback-loop related tasks.

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Detects N+1 query patterns (relation access inside loops without eager loading), full-table get()/all() loads, and unsafe chunk()/cursor() usage in Laravel Eloquent code.

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Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.

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Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).

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Iteratively detects and auto-fixes technical debt in a codebase using three quality criteria from debt-analysis references: conditional branch simplification, encapsulation, and separation of concerns. Applies fixes directly to code, runs existing tests to verify no regressions, re-analyzes, and loops until all high-severity issues are resolved or max iterations (5) reached. Use this skill when you want to automatically improve code quality with real code changes, reduce technical debt systematically, or clean up code to meet quality standards. Trigger on phrases like "fix technical debt", "clean up code quality", "refactor and fix issues", "improve code quality automatically", "apply debt fixes", "fix code problems", "eliminate debt".

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Read-only consolidated snapshot of an SDD Composy workspace: lifecycle stage, task contracts, trace integrity, loops, fleets, and the next action, without changing any file. Use for 'em que pé está o SDD', 'status do fluxo', 'qual a próxima ação', 'where are we in the workflow'. Do NOT use for git, CI, infrastructure, or other plugins' status, or to change state.

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Identifies and fixes common Rust anti-patterns. Use during code review, when seeing excessive clones/unwraps/index loops, or when code fights the borrow checker instead of working with it.

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Automated PR review and CI auto-fix for GitHub and GitLab using the Composio CLI. Pulls diffs, fetches failing job logs, posts review comments, and loops fix commits until checks go green.

日本語の概要は準備中です。原文の説明を表示しています。

Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.

日本語の概要は準備中です。原文の説明を表示しています。

Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).

日本語の概要は準備中です。原文の説明を表示しています。

Run build, deploy, inspect, and fix loops for .NET MAUI apps that already have MAUI DevFlow integrated. USE FOR: launching MAUI apps, selecting devices or emulators, waiting for or recovering agent connections, broker/port/adb connectivity issues, visual tree inspection, screenshots, UI interaction, Blazor WebView CDP debugging, reading DevFlow logs, and iterative app debugging. DO NOT USE FOR: first-time DevFlow package setup (use maui-devflow-onboard), or generic desktop automation unrelated to MAUI. INVOKES: maui devflow CLI, dotnet CLI, Android adb/android tools, and Apple simctl tools.

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Use when a dispatcher, operations manager, or owner asks how to plan loads to minimize empty (deadhead) miles, sequence freight efficiently, balance regional capacity, design dedicated loops, or build a load-pairing strategy across customers. Covers loaded-ratio math, lane balance, region-pair pricing, and software-supported optimization.

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Redux Toolkit selector rules against re-renders, recalculation warnings, and render loops. Use when writing useSelector/useAppSelector or createSelector, deriving state in a connected component, or seeing 'Selector returned a different result when called with the same parameters'.

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自律型Claude Codeループのパターンとアーキテクチャ — シンプルなシーケンシャルパイプラインからRFC駆動のマルチエージェントDAGシステムまで

Hypothesis-Test Loops via REPL for Exploratory Abductive Inference with Gay.jl colors

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Expert 3D modeling specialist with deep knowledge of topology, UV mapping, game-ready and film-ready pipelines, DCC tool workflows (Blender, Maya, ZBrush, 3ds Max, Houdini), retopology, LOD systems, and export pipelines. This skill represents years of production experience distilled into actionable guidance. Use when "3d model, 3d modeling, mesh topology, uv unwrap, uv mapping, retopology, retopo, low poly, high poly, subdivision, subdiv, edge flow, edge loops, polygon modeling, box modeling, hard surface, organic modeling, sculpting, zbrush, blender modeling, maya modeling, 3ds max, LOD, level of detail, game ready mesh, film ready, baking normals, high to low, fbx export, gltf export, texel density, 3d, modeling, topology, uv, game-dev, vfx, blender, maya, zbrush, retopology, lod, hard-surface, organic, sculpting" mentioned.

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Patterns for continuous autonomous agent loops with quality gates, evals, and recovery controls.

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High-level PyTorch framework with Trainer class, automatic distributed training (DDP/FSDP/DeepSpeed), callbacks system, and minimal boilerplate. Scales from laptop to supercomputer with same code. Use when you want clean training loops with built-in best practices.

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Apply a named behavioral science framework to any task — persuasion, nudge design, habit formation, conversion, influence, negotiation, cognitive bias, choice architecture, decision framing. The framework backbone every other Maxim skill loops into for psychological validation.

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Security review and threat work — threat modeling, vulnerability assessment, penetration test, incident response, OWASP Top 10, LLM Top 10, API Top 10, CVE triage, STRIDE, NIST CSF, SBOM. Auto-loops on any task touching PII, auth, payments or regulated data.

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Run a bounded, governed iteration — "loop", "iterate until", "keep going until", "sweep", "ratchet", "until it passes", "coverage to 100". Turns an open-ended autonomous run into a finite loop with checkpoints and explicit stopping conditions.

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Expert skill for building web-based game engines and games using HTML5, Canvas, WebGL, and JavaScript. Use when asked to create games, build game engines, implement game physics, handle collision detection, set up game loops, manage sprites, add game controls, or work with 2D/3D rendering. Covers techniques for platformers, breakout-style games, maze games, tilemaps, audio, multiplayer via WebRTC, and publishing games.

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Patterns and techniques for evaluating and improving AI agent outputs. Use this skill when: - Implementing self-critique and reflection loops - Building evaluator-optimizer pipelines for quality-critical generation - Creating test-driven code refinement workflows - Designing rubric-based or LLM-as-judge evaluation systems - Adding iterative improvement to agent outputs (code, reports, analysis) - Measuring and improving agent response quality

日本語の概要は準備中です。原文の説明を表示しています。