1,551 件 ・ 関連度順
概要と使いどころ
Design guide RNAs for CRISPR-Cas9/Cas12a experiments using CRISPRscan and local scoring algorithms. Score guides for on-target activity using Rule Set 2 and Azimuth models. Use when designing sgRNAs for gene knockout, activation, or repression experiments.
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Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
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Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.
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Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics. Use when predicting disease risk from genome-wide genetic variants.
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Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics. Use when comparing alignment quality, measuring sequence divergence, and analyzing evolutionary patterns.
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Audit, diagnose, or optimize website loading and interaction performance, Core Web Vitals, and Lighthouse performance scores.
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Analyzes market breadth using Monty's Uptrend Ratio Dashboard data to diagnose the current market environment. Generates a 0-100 composite score from 5 components (breadth, sector participation, rotation, momentum, historical context). Use when asking about market breadth, uptrend ratios, or whether the market environment supports equity exposure. No API key required.
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Mine Claude Code session logs for skill idea candidates. Use when running the weekly skill generation pipeline to extract, score, and backlog new skill ideas from recent coding sessions.
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Analyze Stockbee-style Day 1 Episodic Pivot candidates from earnings, guidance raises, M&A, FDA/regulatory approvals, analyst actions, major contracts, product launches, short-squeeze catalysts, or theme/story events. Scores catalyst quality together with gap/range expansion, volume shock, neglect/revaluation context, liquidity, and risk to the EP-day low. Use when the user asks for EP candidates, episodic pivots, Day 1 catalyst trades, game-changing news reactions, delayed EP watchlists, or handoffs into PEAD monitoring.
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Detects market top probability using O'Neil Distribution Days, Minervini Leading Stock Deterioration, and Monty Defensive Sector Rotation. Generates a 0-100 composite score with risk zone classification. Use when user asks about market top risk, distribution days, defensive rotation, leadership breakdown, or whether to reduce equity exposure. Focuses on 2-8 week tactical timing signals for 10-20% corrections.
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Statistical arbitrage tool for identifying and analyzing pair trading opportunities. Detects cointegrated stock pairs within sectors, analyzes spread behavior, calculates z-scores, and provides entry/exit recommendations for market-neutral strategies. Use when user requests pair trading opportunities, statistical arbitrage screening, mean-reversion strategies, or market-neutral portfolio construction. Supports correlation analysis, cointegration testing, and spread backtesting.
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Screen US equities for parabolic exhaustion patterns and generate conditional pre-market short plans, then evaluate intraday trigger fires from live 5-min bars. Phase 1 daily 5-factor scorer (MA extension / acceleration / volume climax / range expansion / liquidity), Phase 2 per-candidate plans for ORL break / first-red 5-min / VWAP fail with explicit borrow / SSR / manual-confirmation gating, Phase 3 one-shot intraday FSM that detects trigger fires and resolves concrete share counts. Covers Phase 1 + Phase 2 + Phase 3.
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Critically review strategy drafts from edge-strategy-designer for edge plausibility, overfitting risk, sample size adequacy, and execution realism. Use when strategy_drafts/*.yaml exists and needs quality gate before pipeline export. Outputs PASS/REVISE/REJECT verdicts with confidence scores.
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Analyze recent post-earnings stocks using a 5-factor scoring system (Gap Size, Pre-Earnings Trend, Volume Trend, MA200 Position, MA50 Position). Scores each stock 0-100 and assigns A/B/C/D grades. Use when user asks about earnings trade analysis, post-earnings momentum screening, earnings gap scoring, or finding best recent earnings reactions.
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Quantifies market breadth health using TraderMonty's public CSV data. Generates a 0-100 composite score across 6 components (100 = healthy). No API key required. Use when user asks about market breadth, participation rate, advance-decline health, whether the rally is broad-based, or general market health assessment.
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Review skills in any project using a dual-axis method: (1) deterministic code-based checks (structure, scripts, tests, execution safety) and (2) LLM deep review findings. Use when you need reproducible quality scoring for `skills/*/SKILL.md`, want to gate merges with a score threshold (for example 90+), or need concrete improvement items for low-scoring skills. Works across projects via --project-root.
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Runs a declarative strategy spec over OHLCV bars with the manifoldbt Rust engine, pairs the fill log into round trips, and emits the eight inputs the backtest-expert skill scores. Use when the user wants to execute a backtest, measure a rule they have described, obtain win rate / average win / average loss / max drawdown from real bars, or feed backtest-expert with measured numbers instead of estimates.
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Quantifies crypto market regime health using free, keyless public data (CoinGecko + Binance funding). Generates a 0-100 composite score across 6 components (100 = risk-on) with a posture recommendation. No API key required. Use when user asks about crypto market conditions, whether it's alt season, BTC dominance, crypto risk-on vs risk-off, funding rates, or whether crypto exposure should be increased or reduced.
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Use when the user asks to "run the weekly social readout", "which denominator does our engagement rate use", or "which posts won this week and what changes next cycle"; produces the organic-social metric dictionary (every rate names its denominator — ERR engagement-by-reach vs ERI by-impressions vs ER-by-follower — locked across periods), median-not-mean per-post rollups with organic and boosted separated, EMV as labeled exec-translation only (never inside any score), an attributed CHAOSS/Orbit-style community-health readout with employees excluded, and the best/worst-performer write-back the next calendar cycle consumes. Not for dollar-ROI math or the ECHO profile result gate verdict — use roi-calculator and social-quality-auditor. 社媒周报/互动率分母/指标字典/复盘回写
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Use when the user asks to "build our social posting calendar", "set weekly slots and queue depth per channel", or "plan the evergreen recycle rotation"; produces the always-on brand calendar — pillar allocation with hero/hub/help balance and give:ask targets (all labeled Estimated starting heuristics to calibrate against own analytics, never scored rules), per-channel recurring slots with queue depth, a batching workflow, an evergreen recycle cycle with freshness re-checks, deliberate open slots for realtime/trend moments fed by trend-spotter go/skip verdicts, and first-comment/publish-order ops — cadence commitments filed to the channel registry, and no batch ships to the queue without a SHIP verdict from social-quality-auditor pre-publish mode. Not for repurposing an existing asset or the paid-amplification calendar — use content-amplifier. 社媒排期/内容日历/栏目配比/常青循环复用
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Use when the user asks to "plan my site structure", "design the page hierarchy / navigation / URL taxonomy", "fix internal linking", or "find orphan pages"; runs two modes — architecture (hierarchy, nav, URL patterns, hub/spoke clusters, Mermaid site maps) and linking (link graph, authority flow, anchor text, orphan disposition, source/target/anchor plan) — and outputs a structure score /100 plus a handoff summary. Not for external backlinks — use offsite-signal-analyzer; not for XML sitemap or indexation issues — use technical-seo-checker. 网站架构/信息架构/站点地图/内链优化
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Use when the user asks to "audit on-page SEO" or "diagnose why a single page dropped"; scores titles, meta, header structure, keyword placement, links, and images with prioritized fixes. Not for E-E-A-T / publish-readiness scoring — use content-quality-auditor; not for crawl / CWV / indexing — use technical-seo-checker. 页面SEO审计/排名诊断
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Use when the user asks to "write SEO content", "draft a blog post / landing page", "update outdated content", or "fix traffic/ranking decay"; two modes — new drafts pages with keywords, headers, snippets, and evidence boundaries; refresh scores decay, prioritizes update work, and produces a republish plan with GEO guidance. Not for AI-citation/GEO readiness scoring — use geo-content-optimizer; not for publish-gate scoring — use content-quality-auditor. SEO文章写作/内容更新/排名恢复
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Use when the user asks to "find influencers", "build an influencer list", or "discover creators in [niche]"; produces a multi-platform candidate pool, per-influencer evidence profiles, authenticity red-flag screening, and a Fit-readiness queue without action ranking. Not for STAR scoring or ranking a known shortlist — use fit-scorer. 达人挖掘/找达人/创作者名单
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