「can」の検索結果

Diagnoses bias, anomalies, and strange-looking results on a specific PostHog experiment. Covers empty / 0-exposure experiments, sample ratio mismatch, identity fragmentation, multi-variant exposure, uneven-split exclusion bias, significance traps (peeking, A/A, Bayesian vs Frequentist), PostHog-vs-SQL discrepancies, and surprises after mid-run edits. Symptom-driven dispatch to the right diagnostic. TRIGGER when: user asks 'is my experiment biased?' or 'why 0 exposures?', references the bias banner, says a variant looks strange / wrong / off, sees significance flipping, notices PostHog numbers disagreeing with their SQL, sees an A/A test showing significance, or reports surprises after mid-run edits. DO NOT TRIGGER when: creating a new experiment (use creating-experiments), only configuring rollout (use configuring-experiment-rollout) or metrics (use configuring-experiment-analytics), or only asking lifecycle questions (use managing-experiment-lifecycle).

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Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautomer canonicalization, stereochemistry standardization, mixture handling, and isotope normalization. Explicitly compares ChEMBL pipeline, canSARchem, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

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Manage timers, cancellation, entity lifetime, asynchronous work, and main-thread state safely.

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Choose and implement local, directed, broadcast, cancellable, and network events.

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Implement actions, cooldowns, DoAfter flows, interruption, cancellation, and authoritative completion safely.

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Design canary deployment strategies for AI. TRIGGERS - Use when user needs help with ai-canary-deployment related tasks.

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Tells you what CARLA on UE 5.5 (branch ue5-dev) cannot do that UE 5.8 (ue58-dev) can, so you do not attempt an unsupported workflow there — no Autoware integration, no ROS 2 middleware choice (FastDDS only), no DLSS or ray-traced-lens camera, no OFPA large-map mount so Town12/13/15 load black, and a few missing World/Actor methods. Also states what is identical, so the ue58 skills can be used directly for everything else. Use when working against a 5.5 checkout, when a ue58 skill's step has no counterpart, or when deciding whether a feature request is possible on 5.5 at all.

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Audit and improve website readiness for AI agents using the Cloudflare "Is It Agent Ready?" scanner (isitagentready.com). Covers scanning via API, interpreting results, generating implementation prompts, and fixing every check. Use when the user mentions "agent ready", "isitagentready", "AI agent scan", "agent readiness", "agent-ready score", "MCP server card", "agent skills index", "markdown for agents", "content signals", "web bot auth", "agent discovery", "RFC 9727", "RFC 8288", "RFC 9728", "SEP-1649", "WebMCP", "x402", "UCP", "ACP", or wants to make a website discoverable and usable by AI agents.

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Generates complete video ad scripts for 15s, 30s, and 60s formats in Darija (Moroccan Arabic dialect) with shot-by-shot breakdowns, Islamic compliance guidelines, global trend alignment (authenticity, sustainability, UGC), and cultural adaptation for Facebook, Instagram, and TikTok. Includes 4 frameworks including a Moroccan-specific storytelling framework.

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This skill enables Claude to perform comprehensive accessibility audits. It uses the accessibility-test-scanner plugin to identify WCAG 2.1/2.2 compliance issues, validate ARIA attributes, check keyboard navigation, and assess screen reader compatibility. Use this skill when the user requests an accessibility scan, audit, or compliance check, or when terms like "WCAG", "ARIA", "screen reader", "accessibility testing", or "a11y" are mentioned. It provides actionable insights for improving web application accessibility.

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Help job seekers use Otameshi Tenshoku to prepare profiles and applications, clarify trial conditions, plan learning visits or paid trial work, and reflect on the experience. Use when a candidate wants to apply for, prepare for, negotiate the scope of, or review an otameshi work experience; do not use to predict whether they will be hired or to judge their aptitude, to state fees, contract terms, or service conditions from memory, or to submit an application, update a profile, or send a message on their behalf. Employer-side requests belong to the employer skills (trial-work-design, trial-listing-draft, applicant-reply and others).

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Review and revise Japanese job-application documents (entry sheets, rirekisho, shokumu-keirekisho) by checking each answer against the question asked, the stated character limit, and the evidence the applicant can actually support, then propose concrete rewrites the applicant decides on. Use when a user wants an ES or resume answer critiqued, tightened, or drafted from their own experience; to assemble a whole shokumu-keirekisho from an experience inventory, use resume-draft instead; do not use to invent experience, to judge pass or fail probability, or to submit an application.

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Predict peptide-MHC class I binding and natural presentation with MHCflurry, NetMHCpan-4.1, and MixMHCpred to nominate candidate CD8 T-cell epitopes. Covers the binding-affinity (BA) vs eluted-ligand (EL/presentation) distinction, why %Rank beats raw nM for cross-allele work, the MS abundance bias that misranks low-expression neoantigens, allele-coverage inequity, and length bias. Use when scanning a protein or peptide set for class I epitopes, scoring neoantigen candidates, or choosing a binding predictor. For CD4/HLA class II see mhc-class-ii-prediction.

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Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.

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Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot with 5'UTR / CDS / 3'UTR scaling; MetaPlotR; deepTools `computeMatrix scale-regions`), peak-centred heatmaps (ComplexHeatmap; deepTools plotHeatmap), IP-vs-input paired browser tracks (bigWig of log2 IP/input via deepTools `bamCompare`; ggcoverage; pyGenomeTracks; Gviz; IGV / UCSC track hubs), DRACH sequence-logo plots (ggseqlogo; MEME), 5'UTR / CDS / 3'UTR stacked-bar feature-distribution summaries, and volcano / MA plots for differential modification. Establishes stop-codon enrichment in the metagene plot as the biological QC anchor for any MeRIP dataset (Dominissini 2012 *Nature* 485:201; Meyer 2012 *Cell* 149:1635 — concurrent founding papers from different labs both showed this independently). Use when producing the canonical metagene plot with stop-codon enrichment as a QC anchor, building paired IP/input genome-browser tracks at single-locus resolution, plotting peak-centred heatmaps clustered by condition, summarising peak distribution across transcript features for figure 1, generating DRACH motif logos as sanity checks on the peak set, rendering volcano plots of differential m6A, or reproducing the Dominissini 2012 / Meyer 2012 stop-codon enrichment plot.

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Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation conventions. Covers EnhancedVolcano, ggplot2, matplotlib, and the apeglm/ashr/normal shrinkage decision. Use when visualizing differential-expression results (RNA-seq, ChIP-seq, ATAC-seq, proteomics) or any per-feature effect-size + p-value table.

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Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautomer canonicalization, stereochemistry standardization, mixture handling, and isotope normalization. Explicitly compares ChEMBL pipeline, canSARchem, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

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Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD-confounded signal under the Schmidt 2020 cis-MR framework, screening on-target adverse phenotypes pheWAS-style, or producing publication-grade STROBE-MR plus PP.H4 evidence for a target gene.

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リリース前の全ファイル静的解析スキル。プロジェクト構造を自動検出し、ソースモジュールごとのサブエージェントと依存関係スキャンを並列実行してコードベース全体の脆弱性を検出する。手動呼び出し専用: /sec-full-scan

ステージング環境にデプロイ済みのサーバーに対してランタイム検証を実行する。HTTPヘッダー・動的プローブ・認証テストに特化。手動呼び出し専用: /sec-runtime-scan [環境名]

Generate a single-file VR-style portfolio website — works are tiled on the inside of a 3D cylinder/sphere (concave wraparound, like an immersive headset), with mouse-controlled head tilt, long-press to drag and browse the infinite canvas, click to open work detail. Includes overlays for About / CV / Contact / Filter. Takes a natural-language description of the studio and works (images + brief copy); outputs ONE working .html file. Runs in BOTH Claude Code (writes to ~/Desktop) and GLM / online chat (outputs HTML inline). Trigger phrases: "做个 VR 作品集", "做个无限画布作品集", "做个穹顶包裹的作品集", "vr-canvas-gen ...", or when user drags this skill folder into chat asking for a wraparound/immersive portfolio site.

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Chief Security Officer mode. Infrastructure-first security audit: secrets archaeology, dependency supply chain, CI/CD pipeline security, LLM/AI security, skill supply chain scanning, plus OWASP Top 10, STRIDE threat modeling, and active verification. Two modes: daily (zero-noise, 8/10 confidence gate) and comprehensive (monthly deep scan, 2/10 bar). Trend tracking across audit runs. Use when: "security audit", "threat model", "pentest review", "OWASP", "CSO review". (gstack) Voice triggers (speech-to-text aliases): "see-so", "see so", "security review", "security check", "vulnerability scan", "run security".

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Post-deploy canary monitoring. Watches the live app for console errors, performance regressions, and page failures using the browse daemon. Takes periodic screenshots, compares against pre-deploy baselines, and alerts on anomalies. Use when: "monitor deploy", "canary", "post-deploy check", "watch production", "verify deploy". (gstack)

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Security checks for repository ingestion — scans repos for poisoned examples, dependency and supply-chain attacks, file/path traversal, format-based attacks, and enforces quarantine-before-commit. Load as part of the secure-* skill sequence whenever an agent reads, ingests, or learns from a GitHub repository. Also load when the user asks to check a repo for poisoned code, scan dependencies, verify supply chain safety, check for path traversal, scan repo files for attacks, or audit a repo before ingestion. Covers Issues 3, 4, 7, 8 from the agent security threat model: poisoned training data, dependency attacks, file/path attacks, and format-based attacks.

日本語の概要は準備中です。原文の説明を表示しています。