「transition」の検索結果

Assesses organizational readiness for post-quantum cryptography migration per NIST FIPS 203/204/205 standards. Performs cryptographic inventory scanning to identify quantum-vulnerable algorithms (RSA, ECDH, ECDSA), evaluates hybrid TLS configurations with X25519MLKEM768, and validates CRYSTALS-Kyber (ML-KEM) and CRYSTALS-Dilithium (ML-DSA) readiness. Implements crypto-agility assessment using oqs-provider for OpenSSL. Use planning yaparken or executing the transition from classical to post-quantu...

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Framer Motion React animation library skill — declarative animations, gestures, layout transitions, scroll-triggered animations, variants, AnimatePresence, and performance optimization.

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Generates the monthly revenue-accountable marketing report that B2B SaaS marketing leaders deliver to CEOs, CFOs, executive teams, and boards. Use when preparing the monthly CEO report, drafting the marketing section of a board deck, defending budget decisions, diagnosing pipeline gaps, or transitioning marketing from MQL/SQO reporting to revenue, CAC payback, and forward pipeline coverage. Designed for B2B SaaS demand generation leaders who own pipeline targets across segments, geos, and motions, and need to explain marketing's revenue contribution in executive language.

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Follow-up scout for the Signals inbox itself. Watches reports that recently transitioned to resolved (an implementation PR merged) and, after a deployment soak window, re-measures the underlying problem to check the fix actually held — plus a strictly-gated escalation check on recently dismissed reports. Emits findings only when a shipped fix demonstrably didn't hold; confirmations and unverifiable verdicts become durable memory and an empty close-out. Self-contained peer in the signals-scout-* fleet — no dependencies on other skills.

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Guides experiment state transitions: launching, pausing, resuming, ending, shipping variants, archiving, resetting, duplicating, and copying to another project. Covers preconditions, implications for variant assignment and analysis, and the decision framework for when to use each action. TRIGGER when: user asks to launch, pause, resume, end, ship, archive, reset, duplicate, or copy an experiment to another project. DO NOT TRIGGER when: user is creating an experiment (use creating-experiments), configuring rollout (use configuring-experiment-rollout), or setting up metrics (use configuring-experiment-analytics).

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Monte Carlo simulation for statistical mechanics — Ising model, Metropolis-Hastings, Wolff cluster algorithm, observables (magnetization, susceptibility, specific heat), finite-size scaling, and critical phenomena analysis.

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Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

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Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

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Build an animation from scratch, making the decisions in the order that determines whether it feels right — should it animate at all, what purpose, which tool, which properties, which curve and duration, how it interrupts, how it exits. Writes the implementation. Use when asked to animate something, add motion, make a component feel alive, or build a transition. For critiquing existing motion use review-animations; for auditing a whole codebase use improve-animations.

日本語の概要は準備中です。原文の説明を表示しています。

Plan transition from freelancer to agency with scaling. TRIGGERS - Use when user needs help with agency-builder related tasks.

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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

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Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

日本語の概要は準備中です。原文の説明を表示しています。

Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

日本語の概要は準備中です。原文の説明を表示しています。

Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

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Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. Use when the user mentions adding animation, transitions, micro-interactions, motion design, hover effects, or making the UI feel more alive.

日本語の概要は準備中です。原文の説明を表示しています。

Extract a thesis's dependency fingerprint — the external variables its bull case actually rests on (key customers, suppliers/inputs, technology transitions, macro drivers, single points of failure). Use when user says "dependency map", "what does [TICKER] depend on", "dependency fingerprint", or "map exposures for [TICKER]".

日本語の概要は準備中です。原文の説明を表示しています。

Smooth color transitions and gradient-rich surfaces for modern, playful interfaces with visual depth.

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Implement exactly one SDD Composy task in the ready state with dependency preflight, TDD RED evidence, allowed paths, real verification commands, and the guarded transition to qa_required. Use when a ready task should be executed — 'executar a TASK-003', 'implementar a próxima tarefa', 'run task 4'. Do NOT use for changes without an approved task (sdd-quick), for autonomous multi-stage correction (sdd-loop), or for QA, review, or verification.

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Generate and safely advance the SDD Composy task projection from approved PRD, stories, and TechSpec: import contracts, list/next/show, and guarded start/block/transition/verify. Use when work must be decomposed or a task's state inspected or moved — 'quebrar a spec em tarefas', 'listar as tarefas', 'qual a próxima task', 'mark TASK-003 blocked'. Do NOT use to implement a task (sdd- execute), reconcile Markdown and JSON (sdd-sync), or for a status overview (sdd- status).

日本語の概要は準備中です。原文の説明を表示しています。

Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

日本語の概要は準備中です。原文の説明を表示しています。

Route user requests to the right skill, decompose complex work into parallel subagents, and manage project phase transitions. Load when the user asks "what should I do next", "which skill should I use", "orchestrate this", "run the full workflow", "split this into parallel tasks", or when a complex request spans multiple skills. Also triggers on "coordinate agents", "parallel execution", "task decomposition", "agent workflow", "what phase am I in", or when the user gives a broad instruction that requires multiple skills in sequence. This is the project's brain — it decides what runs, when, and whether to parallelise.

日本語の概要は準備中です。原文の説明を表示しています。

Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

日本語の概要は準備中です。原文の説明を表示しています。

Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

日本語の概要は準備中です。原文の説明を表示しています。