「by」の検索結果

Use when you need to auto-log all tool interactions into a self-organizing vector DB with instant recall. Intercepts interactions, extracts key information, generates embeddings, stores in LanceDB, auto-categorizes, and builds a retrieval index. Inspired by OpenClaw SQLite LCM + summary DAG pattern.

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Independent LLM judge evaluates task completion separately from the executing agent, catching false success claims by reviewing task goal, actions taken, final state, and evidence. Produces PASS/FAIL with confidence score and reasoning.

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Focuses on pandas-specific rules for data manipulation, including method chaining, data selection using loc/iloc, and groupby operations.

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Create structured incident response runbooks with step-by-step procedures, escalation paths, and recovery actions. Use when building runbooks, responding to incidents, or establishing incident response procedures.

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Advanced Git operations wrapper. Optimizes token usage by guiding complex git workflows into efficient CLI commands.

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Game development expert including DragonRuby, Unity, and game mechanics

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Workflow for repository reconnaissance and operations using GitHub CLI (gh). Optimizes token usage by using structured API queries instead of blind file fetching.

日本語の概要は準備中です。原文の説明を表示しています。

Programmatic code style validation using AST analysis. Complements (not replaces) code-style rules by providing automated checking and instant feedback.

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Byzantine consensus voting for multi-agent decision making. Implements voting protocols, conflict resolution, and agreement algorithms for reaching consensus among multiple agents.

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Creates specialized AI agents on-demand when no existing agent matches a request. Use when the Router cannot find a suitable agent for a task. Enables self-evolution by generating persistent agents.

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Use when you need semantic retrieval from perpetual memory at query time. Parses query intent, searches vector store, ranks by relevance and recency, and injects context. Complements memory-search.cjs with the perpetual_memory LanceDB table.

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用户需要为不同的人/场景定制方案时; 当"一刀切"方案失效时; 当需要根据个体差异(体质/能力/偏好)调整参数时。 不适用于: 标准化流程不需要定制的场景、群体层面的统一方案。

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Parallel map-reduce bulk ingest for large source sets. Map phase dispatches read-only knowledge-extractor agents (≤N-wide, default Haiku) emitting per-source JSON extracts; Python routes extracts by target library file (fuzzy-merging new topics, pre-allocating new files, flagging oversized topics); reduce phase dispatches one agent-knowledge-updater per file (parallel, one writer per file); single shelf-index rebuild + one log.md entry. Resumable. Supersedes kb-ingest-batch.

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Parse all `# implements:` annotations in source code and emit `library/_code-index.md` as a shelf-index. Also extracts cross-module import edges and writes `library/_dependency-edges.md`. Idempotent — re-running produces byte-identical output if no annotations or imports changed.

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Rebuild the knowledge base shelf-index with hash-based change detection. Incremental by default — only re-extracts files whose content has changed since the last index. Use after ingesting new sources, after editing library files, or whenever the librarian agent reports a stale index.

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Drive agent-knowledge-updater over a batch of staged files in library/raw/. Tracks progress in .batch-progress.json for resume support. Sequential by default; --parallel <N> opt-in (max 5). Single shelf-index rebuild and one consolidated log.md entry at the end.

日本語の概要は準備中です。原文の説明を表示しています。

Mock skill shipped by the sample bundle for installer testing

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Cofold protein-ligand, protein-protein, and nucleic-acid complexes with Boltz-2, and predict binding affinity with its trained affinity head. Use this skill to build Boltz input YAML, run structure prediction with MSAs, pocket constraints, templates, and modified residues, screen compound libraries by cofolding, and interpret confidence scores (pLDDT, pTM, ipTM, PDE) and affinity output (binder probability and log10 IC50). Also trigger on Boltz, Boltz-1, Boltz-2, cofolding, boltz predict, affinity_pred_value, affinity_probability_binary, ipTM, or open-weights AlphaFold3 alternatives.

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Decide whether a protein has a pocket worth targeting, and where it is, before committing to a docking or design campaign. Use this skill to run fpocket cavity detection, rank cavities by druggability and volume, compare apo and holo conformations to spot induced fit, identify allosteric and cryptic cavities that only open in simulation, and convert a chosen cavity into the search box coordinates a docking run needs. Also trigger on fpocket, cavity detection, druggability score, alpha sphere, cryptic pocket, allosteric site, pocket volume, hotspot mapping, or undruggable target assessment.

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Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological relationships across genes and proteins, drugs, diseases, phenotypes, pathways, biological processes, exposures and anatomy. Use this skill to search entities by name, pull direct neighbours and their evidence types, summarise the local network around a disease, and find direct or two-hop drug-disease connections for repurposing hypotheses. Also trigger on PrimeKG, kg.csv, Harvard Dataverse knowledge graph, disease_protein, drug_protein, indication and contraindication edges, or network pharmacology over a biomedical knowledge graph.

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Turn in vitro potency and animal pharmacokinetics into a defensible human dose projection — the arithmetic that decides whether a compound can reach its target concentration safely. Use this skill for non-compartmental analysis of a concentration-time profile (AUC, Cmax, terminal half-life, clearance, volume of distribution), one- and two-compartment simulation of a dosing regimen, interspecies allometric scaling, human-equivalent dose conversion by body surface area, and the exposure margin between a projected therapeutic concentration and a toxicology no-effect level. Also trigger on non-compartmental analysis, AUC, clearance, volume of distribution, allometric scaling, human equivalent dose, first-in-human, NOAEL, therapeutic index, or exposure margin.

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Query the ChEMBL database web services for measured bioactivity data, compound records and calculated properties, targets, assays, mechanisms of action, drug indications and warnings. Use this skill to build curated SAR or QSAR datasets for a target, look compounds up by SMILES, InChIKey, name, or ChEMBL id, run similarity and substructure searches, and check what chemistry is already known against a protein. Also trigger when a query mentions ChEMBL ids (CHEMBL...), pChEMBL values, IC50/Ki/Kd/EC50 retrieval, assay confidence scores, or ebi.ac.uk/chembl.

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Number antibody variable domains, annotate CDRs, and assess developability from sequence. Use this skill to apply IMGT, Kabat, Chothia, Martin, or AHo numbering with ANARCI, delimit CDRs and framework regions, scan for chemical liabilities (N-glycosylation sequons, deamidation NG, isomerisation DG, oxidation, unpaired cysteine, fragmentation), compute pI, net charge, extinction coefficient and hydrophobicity, and plan humanisation by CDR grafting. Also trigger on antibody, nanobody, VHH, scFv, Fab, CDR, framework, ANARCI, abnumber, IgBLAST, OAS, SAbDab, humanization, Vernier residues, or developability.

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Retrieve protein sequences, annotation, and structures from UniProtKB, the RCSB PDB, and AlphaFold DB. Use this skill to resolve a gene or protein name to a UniProt accession, pull sequences and FASTA files, find binding sites and domains, search the PDB by UniProt accession, sequence, ligand, or text, download mmCIF/PDB coordinates and biological assemblies, fetch AlphaFold models with their pLDDT confidence, and check whether a structure is actually usable before docking or simulating it. Also trigger on UniProt accessions, PDB ids, rest.uniprot.org, search.rcsb.org, files.rcsb.org, alphafold.ebi.ac.uk, id mapping, SEQRES, or missing residues.

日本語の概要は準備中です。原文の説明を表示しています。