「implement」の検索結果

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Implements missing-data sensitivity analyses for confirmatory clinical trials including MMRM under MAR (with Kenward-Roger correction), reference-based multiple imputation (J2R, CR, CIR, LMCF per Carpenter-Roger 2013), Permutt delta-adjustment / tipping-point analysis, pattern-mixture identifying restrictions (CCMV, NCMV, ACMV), and the Cro vs Bartlett variance debate. Use when handling missing primary or secondary endpoint data in regulatory submissions following NRC 2010 and ICH E9(R1).

日本語の概要は準備中です。原文の説明を表示しています。

Implements multiplicity control for confirmatory clinical trials using graphical procedures (Bretz-Maurer-Hommel), gatekeeping (parallel, serial, mixed), Hochberg/Hommel/Holm with PRDS, and the closed-testing principle (Marcus-Peritz-Gabriel; Goeman 2021 admissibility). Covers FDA Multiple Endpoints Final Guidance (October 2022), graphical procedures via R gMCP, primary + key-secondary + subgroup hierarchies, and FWER vs FDR distinction. Use when designing the multiplicity strategy for confirmatory trials with multiple primary or key secondary endpoints.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to track recent and upcoming SMS methodology changes from FMCSA. Covers proposed rule changes, comment periods, and implementation timelines.

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Use this skill when referring a driver to SAP after a positive test or refusal. Covers SAP selection, the evaluation/treatment cycle, return-to-duty test, and follow-up testing schedule.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when implementing or renewing supervisor reasonable-suspicion training. Covers the 60-minute alcohol + 60-minute drug training requirement, recordkeeping, and refresher cadence.

日本語の概要は準備中です。原文の説明を表示しています。

Designs, reconciles, and reviews an end-to-end Drydock program for safely staging agent runtimes: immutable worktree provenance, disposable VM containment, typed effect brokerage, global body accounting, resurrection, subscription-capacity economics, context compaction, operator control, evidence, and promotion. Use when several Drydock contracts must compose into one architecture, implementation hypertree, diagram set, or release plan. NOT for launching Port Daddy, running an untrusted subject, replacing focused containment/resurrection/capacity audits, or treating a design packet as runtime authority.

日本語の概要は準備中です。原文の説明を表示しています。

Create and review Cloudflare Durable Objects. Use when building stateful coordination (chat rooms, multiplayer games, booking systems), implementing RPC methods, SQLite storage, alarms, WebSockets, or reviewing DO code for best practices. Covers Workers integration, wrangler config, and testing with Vitest. Biases towards retrieval from Cloudflare docs over pre-trained knowledge.

日本語の概要は準備中です。原文の説明を表示しています。

Design error handling strategies for TypeScript and Python applications — exception hierarchies, Result/Either types, retry patterns, error boundaries, and structured error logging. Use when designing error handling architecture, choosing between exceptions and Result types, implementing retry logic, or building error recovery flows. Activate on "error handling", "exception hierarchy", "Result type", "retry pattern", "circuit breaker", "error boundary", "Pokemon exception". NOT for debugging specific runtime errors, logging infrastructure setup, or monitoring/alerting configuration.

日本語の概要は準備中です。原文の説明を表示しています。

Expert in temporal event detection, spatio-temporal clustering (ST-DBSCAN), and photo context understanding. Use for detecting photo events, clustering by time/location, shareability prediction, place recognition, event significance scoring, and life event detection. Activate on 'event detection', 'temporal clustering', 'ST-DBSCAN', 'spatio-temporal', 'shareability prediction', 'place recognition', 'life events', 'photo events', 'temporal diversity'. NOT for individual photo aesthetic quality (use photo-composition-critic), color palette analysis (use color-theory-palette-harmony-expert), face recognition implementation (use photo-content-recognition-curation-expert), or basic EXIF timestamp extraction.

日本語の概要は準備中です。原文の説明を表示しています。

Aesthetic assessment and design scoring across 6 dimensions. Use for UI critique, design review, visual quality assessment, remix suggestions. Activate on "design critique", "aesthetic review", "UI assessment", "visual quality", "design score", "remix this design". NOT for implementation (use frontend-developer), accessibility-only audits (use color-contrast-auditor), or brand identity creation.

日本語の概要は準備中です。原文の説明を表示しています。

Builds comprehensive design systems and design bibles with production-ready CSS. Expert in design tokens, component libraries, CSS architecture. Use for design system creation, token architecture, component documentation, style guide generation. Activate on "design system", "design tokens", "CSS architecture", "component library", "style guide", "design bible". NOT for typography deep-dives (use typography-expert), color theory mathematics (use color-theory-palette-harmony-expert), brand identity strategy (use web-design-expert), or actual UI implementation (use web-design-expert or native-app-designer).

日本語の概要は準備中です。原文の説明を表示しています。

Chooses and designs developer surfaces for an agentic product: SDK, CLI, MCP, GUI, API, webhooks, and pd tube-style listener/sender workflows. Use when deciding why a user belongs in an SDK versus CLI/MCP/GUI, planning Python SDK parity, or making agent invocation easy across languages. NOT for implementing the full SDK, generic API docs, or UI visual design.

日本語の概要は準備中です。原文の説明を表示しています。

Star schema, snowflake schema, SCD types, and Kimball methodology for analytical data modeling. Activate on: dimensional model, star schema, snowflake schema, SCD, fact table, dimension table, Kimball, grain, surrogate key. NOT for: dbt implementation (use dbt-analytics-engineer), warehouse tuning (use data-warehouse-optimizer).

日本語の概要は準備中です。原文の説明を表示しています。

Implementing distributed tracing with W3C Trace Context — the byte-precise `traceparent` and `tracestate` header formats, OpenTelemetry's W3CTraceContextPropagator as the modern default (replacing X-B3-* and X-Datadog-*), head vs tail sampling, and HTTP→SQL trace propagation via sqlcommenter. Grounded in the W3C REC and OpenTelemetry specs. NOT for OTel metrics/logs pipelines, vendor backend setup (Datadog/Honeycomb/Jaeger/Tempo), or browser RUM tracing.

日本語の概要は準備中です。原文の説明を表示しています。

Handle mental health crisis situations in AI coaching safely. Use when implementing crisis detection, safety protocols, emergency escalation, or suicide prevention features. Activates for crisis keywords, safety planning, hotline integration, and risk assessment.

日本語の概要は準備中です。原文の説明を表示しています。

Specifies bounded DAG execution contracts and evaluates executor receipts for dispatch, cancellation, joins, and effect reconciliation. Use when an implementation must bind a planned DAG to named runtime controls. NOT for claiming an executor is active, spawning agents, or certifying an effect from a plan.

日本語の概要は準備中です。原文の説明を表示しています。

Detect crisis signals in user content using NLP, mental health sentiment analysis, and safe intervention protocols. Implements suicide ideation detection, automated escalation, and crisis resource integration. Use for mental health apps, recovery platforms, support communities. Activate on "crisis detection", "suicide prevention", "mental health NLP", "intervention protocol". NOT for general sentiment analysis, medical diagnosis, or replacing professional help.

日本語の概要は準備中です。原文の説明を表示しています。

Implement AI chatbot analytics and conversation monitoring. Use when adding conversation metrics, tracking AI usage, measuring user engagement with chat, or building conversation dashboards. Activates for AI analytics, token tracking, conversation categorization, and chat performance.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose when intuitive judgment, agent confidence, or expert routing can be trusted by classifying environment validity, feedback quality, and task-boundary fit. Use for confidence calibration, agent routing, expertise audits, and escalation design. NOT for deterministic implementation tasks, pure syntax debugging, or domains with explicit verifiable answers.

日本語の概要は準備中です。原文の説明を表示しています。

Runs an iterative, conversational product-discovery process with a founder/stakeholder: structured interview, live low-fi wireframing, a linked feature/page node-graph built up as you go, a founder-confirmed lock-in checkpoint, then a generated PRD, a Mermaid-rendered sitemap, and a mockup with a full design system (palette, typography, dark mode). Use when building or operating an AI product-discovery chatbot, or when running founder/stakeholder discovery by hand and you need the structure (interview script, node-graph schema, PRD template, design-system handoff order). NOT for implementing the spec'd product once locked — hand off to feature-specific skills (ideal-web-app-builder, tailwind-v4-expert, color-theory-palette-harmony-expert, typography-expert, dark-mode-design-expert) for that. NOT for one-shot PRD generation without an interview loop — if the founder already has a written spec, this process is unnecessary overhead.

日本語の概要は準備中です。原文の説明を表示しています。

Design and implement systematic checklists that reduce errors by 30-50% in complex, high-stakes domains (medicine, aviation, construction, finance). NOT for simple tasks or when comprehensive instruction is needed.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose when intuitive judgment, agent confidence, or expert routing can be trusted by classifying environment validity, feedback quality, and task-boundary fit. Use for confidence calibration, agent routing, expertise audits, and escalation design. NOT for deterministic implementation tasks, pure syntax debugging, or domains with explicit verifiable answers.

日本語の概要は準備中です。原文の説明を表示しています。

Render mathematically-faithful Turkish marbling (Ebru) and paper-marbling with closed-form coordinate-deformation maps — a drop is a radial outward push, a comb/tine is a decaying shear, all composed as homeomorphisms over colored region boundaries. No fluid solver, runs 60fps on a 2D canvas. Use when building a marbling/Ebru toy or generative-art renderer, implementing drop/comb/wave/swirl deformations, scripting traditional patterns (Battal, Gel-Git, Şal, Bülbül Yuvası), keeping combed edges crisp via adaptive resampling, modeling ox-gall shouldering for crisp ring-in-ring drops, or exporting high-DPI marbled prints. NOT for real fluid / Navier-Stokes simulation, metaball / alpha-blended "smoke" blob effects, raster image-processing filters, or non-marbling generative art.

日本語の概要は準備中です。原文の説明を表示しています。