「nps」の検索結果

Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller or when highest germline calling accuracy is required.

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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.

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Deep learning-based variant calling from long reads using Clair3 for SNPs and small indels. Use when calling germline variants from ONT or PacBio alignments, particularly when high accuracy is needed for clinical or research applications.

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Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.

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Establish channels and processes for capturing and processing post-launch feedback during PRD v0.9 Go-to-Market. Triggers on requests to set up feedback systems, capture user input, or when user asks "how do we collect feedback?", "feedback loop", "user research", "post-launch feedback", "customer feedback", "NPS", "voice of customer". Outputs CFD- entries specialized for post-launch feedback capture.

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产品设计 / UX 设计 (产品设计 / UX 设计 (Product Design / UX Design) — 数字产品的用户体验设计：从用户研究 → 信息架构 → 交互设计 → 视觉/UI → 可用性测试 → 设计系统的认知操作系统，面向 UX designer / product designer / interaction designer / UX researcher / design systems engineer / design lead，以及想入行、转岗、服务这行(设计外包、设计工具厂商、研究平台)的视角。覆盖: (a) 第一性张力 — **用户中心/研究驱动 (user-centered, 'you are not the user', research before pixels, observe behavior not opinions) ⇄ 商业目标/约束/交付 (business goals, north-star metrics, ship it, designer 服务于产品成功不是个人作品集)**; **设计直觉/品味/craft (taste, aesthetics, 'attractive things work better' — Norman 情感化设计) ⇄ 数据/实验/A-B 测试 (data-driven, metrics, experimentation, 'opinions are not data')**; **用户说的 (stated preference, 访谈里说喜欢) ⇄ 用户做的 (revealed behavior, 行为观察 > 自陈, usability test 看人真实卡在哪)**; **一致性/设计系统/规范 (consistency, design system, Jakob's law 用户带着别处的习惯来, 复用组件) ⇄ 创新/打破模式 (innovation, 该不该破规范)**; **减法/简化 (simplicity, Krug 'Don't Make Me Think', less but better — Dieter Rams) ⇄ 功能丰富/利益相关者塞需求 (feature creep, stakeholder pressure)**; **UX(体验/流程/研究) ⇄ UI(视觉/像素/组件)** 的职责之争, **designer 该不该写代码 (design engineer / 'should designers code')**; (b) 核心工作流 / pipeline (最标准、最易蒸高质量+CLI 化) — Double Diamond (发现 discover → 定义 define → 开发 develop → 交付 deliver) / Design Thinking (共情 empathize → 定义 → 构思 ideate → 原型 prototype → 测试 test) / Design Sprint (Jake Knapp 5 天冲刺); 完整链: 用户研究 (访谈/问卷/可用性测试/卡片分类) → persona / journey map / JTBD → 信息架构 IA + 用户流 user flow → 线框 wireframe (低保真) → 交互/原型 prototype (高保真) → 视觉 UI / 设计系统落地 → 可用性测试 usability testing → handoff 给开发 → 度量迭代 (北极星 / HEART 框架); (c) 工具栈 — 设计/原型 (Figma 绝对主导 / Sketch 衰退 / Adobe XD 已停更 / Framer 高保真+建站 / Penpot 开源 / Principle / ProtoPie 微交互); 协作白板 (FigJam / Miro / Mural); 用户研究 (Maze / UserTesting / Lookback / Dovetail 研究库 / Optimal Workshop 卡片分类树测试 / Hotjar / Microsoft Clarity 热图); 设计系统/交付 (Storybook / 蓝湖(中) / Zeplin / design tokens / Tokens Studio); 度量 (Amplitude / Mixpanel / 北极星指标); AI 新兴 (Figma AI / v0 by Vercel / Galileo AI / Uizard / Cursor 给 design engineer); (d) 知识正典 — Don Norman《The Design of Everyday Things》(affordance/signifier/mapping 圣经)、Steve Krug《Don't Make Me Think》(可用性入门)、Alan Cooper《About Face》《The Inmates Are Running the Asylum》(交互设计/persona 起源)、Jakob Nielsen 10 Usability Heuristics + NN/g 文章库、Jake Knapp《Sprint》、Jeff Gothelf《Lean UX》、Teresa Torres《Continuous Discovery Habits》、Erika Hall《Just Enough Research》、Julie Zhuo《The Making of a Manager》、《Refactoring UI》(Adam Wathan/Steve Schoger)、《Universal Principles of Design》、Laws of UX (Jon Yablonski)、《100 Things Every Designer Needs to Know About People》(Susan Weinschenk)、IDEO/Stanford d.school 设计思维材料; (e) figures/流派 — 认知心理/人因派 (Don Norman 认知科学奠基、Susan Weinschenk 行为心理、Kathryn Whitenton); 可用性工程派 (Jakob Nielsen 启发式/折扣可用性、Steve Krug、Jared Spool UIE); 交互设计/目标导向派 (Alan Cooper goal-directed/persona、Kim Goodwin); 设计思维派 (IDEO Tim Brown、David Kelley d.school); 精益/持续探索派 (Jeff Gothelf Lean UX、Teresa Torres continuous discovery、Marty Cagan《Inspired》产品发现); 设计系统/系统化派 (Brad Frost Atomic Design、Nathan Curtis design tokens、Alla Kholmatova); 视觉/UI craft 派 (Adam Wathan & Steve Schoger Refactoring UI、Dieter Rams 'less but better' 工业设计遗产); 设计领导/职业派 (Julie Zhuo、Aarron Walter 情感化设计、John Maeda); 移动优先 (Luke Wroblewski 'Mobile First'); (f) 行业话术/黑话 — affordance 可供性 / signifier 意符 / mental model 心智模型 / IA 信息架构 / heuristic evaluation 启发式评估 / usability 可用性 / a11y accessibility 无障碍 / WCAG / persona 用户画像 / journey map 用户旅程 / JTBD jobs-to-be-done / north-star metric 北极星 / HEART 框架 / wireframe 线框 / mockup / prototype 原型 / fidelity 保真度 (lo-fi/hi-fi) / design system 设计系统 / design token 设计令牌 / atomic design 原子设计 / component library 组件库 / handoff 交付 / red routes 关键路径 / dark pattern 暗黑模式 / Fitts's law / Hick's law / Jakob's law / Miller 7±2 / progressive disclosure 渐进披露 / above the fold / hamburger menu / skeuomorphism vs flat / micro-interaction / empty state / edge case / happy path / design debt 设计债 / dogfooding / dot voting / affinity mapping 亲和图 / card sorting 卡片分类 / tree testing / A/B test / NPS / SUS (System Usability Scale); (

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管理咨询 (管理咨询 (Management Consulting) — 战略与管理咨询的职业认知操作系统，从业者/咨询顾问/想入行者/采购咨询服务的客户视角。覆盖: (a) 第一性张力 — 假设驱动 (hypothesis-driven / answer-first / Day-1 answer) 的「先有答案再验证」⇄ 数据驱动 (data-led / bottom-up) 的「先穷尽事实再归纳」，这行的核心张力是「先射箭再画靶 vs 先画靶再射箭」，资深人偏 top-down 假设树减少 boil-the-ocean，但要时刻防 confirmation bias; 以及更深层的张力 — 「卖洞见 (insight / so-what) vs 卖工时 (analysis / 体力)」，「客户影响 (client impact / 落地) vs 智识严谨 (intellectual rigor / 漂亮 deck)」; (b) 方法论正典 (最标准化、最易蒸出高质量) — MECE (相互独立完全穷尽)、issue tree / logic tree (问题树/逻辑树)、hypothesis-driven problem solving (假设驱动)、Pyramid Principle (Minto 金字塔原理: SCQA 情境-冲突-疑问-回答 + 结论先行 + 自上而下 + 归纳/演绎)、80/20 (帕累托/抓大放小)、so-what (所以呢/洞见提炼)、storyline (故事线/ghost deck 鬼影稿)、driver tree / profit tree、2x2 矩阵、value chain、frameworks (Porter 五力/3C/4P/7S/BCG 矩阵/价值链) 既是脚手架也是陷阱 (套框架 vs 真洞见); (c) 行业结构 — MBB (McKinsey/BCG/Bain 战略三巨头) vs Big Four 咨询臂 (Deloitte/PwC Strategy&/EY-Parthenon/KPMG) vs 精品战略所 (Oliver Wyman/Kearney/Roland Berger/L.E.K./Arthur D. Little) vs 专业/职能 boutique (运营/数字化/PE 尽调); up-or-out (非升即走)、leverage model (杠杆模型: 1 个合伙人带多个 EM/咨询师/分析师的金字塔)、partner/principal/EM(项目经理)/associate(咨询师)/analyst(分析师) 职级; (d) 项目交付模型 (the case/study/engagement) — 提案/SOW (scope of work)、problem definition (问题定义/真问题 vs 表象问题)、workplan (工作计划)、hypothesis tree (假设树)、analysis (分析/建模)、synthesis (综合)、recommendation (建议)、implementation (落地); 客户管理 (steering committee 指导委员会、stakeholder 利益相关方、对齐); (e) 产出物 — the deck (PPT 幻灯片是咨询的母语)、executive summary、action title (行动标题/每页一句话结论)、ghost deck (先搭骨架后填数据)、Excel 财务模型、framework 图; (f) 职业/招聘 — case interview 生态 (案例面试: Victor Cheng LOMS/Case in Point/market sizing 市场估算/估算题/fit 行为面)、网申-笔试-案例面、up-or-out、exit options (退出路径: PE/VC/corp dev 企业发展/战略岗/创业/industry); (g) 争议/批判 — 咨询的价值之辩 (「借你的表告诉你时间」「frameworks 是剧场表演 vs 真洞见」Matthew Stewart《The Management Myth》)、McKinsey 的丑闻 (Purdue 阿片类/独裁政府/ICE/利益冲突, Bogdanich & Forsythe《When McKinsey Comes to Town》)、咨询 vs 自建战略部、generalist 通才 vs specialist 专才之争、AI/GenAI 对初级分析师工作的冲击; (h) 流派 — 战略经典 (Porter 定位学派/五力 vs 资源基础观 RBV vs 蓝海战略 Kim&Mauborgne vs 颠覆式创新 Christensen vs Mintzberg 应急战略批判 planning school); 三巨头气质分野 (McKinsey 事实驱动/CEO 信任/通才, BCG 概念/思想领导力/经验曲线/增长-份额矩阵, Bain 结果导向/NPS 净推荐值/PE 关系/与客户深度绑定)。不含: 投行 M&A/财务顾问 (估值/承销超出范畴)、纯 IT 实施/系统集成 (SI 人力外包)、纯审计/税务、纯人力 RPO/猎头、内部战略部 only (虽相关但本 skill 聚焦专业服务咨询的外部视角)。) Master OS — automated mastery of 管理咨询 (Management Consulting) — 战略与管理咨询的职业认知操作系统，从业者/咨询顾问/想入行者/采购咨询服务的客户视角。覆盖: (a) 第一性张力 — 假设驱动 (hypothesis-driven / answer-first / Day-1 answer) 的「先有答案再验证」⇄ 数据驱动 (data-led / bottom-up) 的「先穷尽事实再归纳」，这行的核心张力是「先射箭再画靶 vs 先画靶再射箭」，资深人偏 top-down 假设树减少 boil-the-ocean，但要时刻防 confirmation bias; 以及更深层的张力 — 「卖洞见 (insight / so-what) vs 卖工时 (analysis / 体力)」，「客户影响 (client impact / 落地) vs 智识严谨 (intellectual rigor / 漂亮 deck)」; (b) 方法论正典 (最标准化、最易蒸出高质量) — MECE (相互独立完全穷尽)、issue tree / logic tree (问题树/逻辑树)、hypothesis-driven problem solving (假设驱动)、Pyramid Principle (Minto 金字塔原理: SCQA 情境-冲突-疑问-回答 + 结论先行 + 自上而下 + 归纳/演绎)、80/20 (帕累托/抓大放小)、so-what (所以呢/洞见提炼)、storyline (故事线/ghost deck 鬼影稿)、driver tree / profit tree、2x2 矩阵、value chain、frameworks (Porter 五力/3C/4P/7S/BCG 矩阵/价值链) 既是脚手架也是陷阱 (套框架 vs 真洞见); (c) 行业结构 — MBB (McKinsey/BCG/Bain 战略三巨头) vs Big Four 咨询臂 (Deloitte/PwC Strategy&/EY-Parthenon/KPMG) vs 精品战略所 (Oliver Wyman/Kearney/Roland Berger/L.E.K./Arthur D. Little) vs 专业/职能 boutique (运营/数字化/PE 尽调); up-or-out (非升即走)、leverage model (杠杆模型: 1 个合伙人带多个 EM/咨询师/分析师的金字塔)、partner/principal/EM(项目经理)/associate(咨询师)/analyst(分析师) 职级; (d) 项目交付模型 (the case/study/engagement) — 提案/SOW (scope of work)、problem definition (问题定义/真问题 vs 表象问题)、workplan (工作计划)、hypothesis tree (假设树)、analysis (分析/建模)、synthesis (综合)、recommendation (建议)、implementation (落地); 客户管理 (steering committee 指导委员会、stakeholder 利益相关方、对齐); (e) 产出物 — the deck (PPT 幻灯片是咨询的母语)、executive summary、action title (行动标题/每页一句话结论)、ghost deck (先搭骨架后填数据)、Excel 财务模型、framework 图; (f) 职业/招聘 — case interview 生态 (案例面试: Victor Cheng LOMS/Case in Point/market sizing 市场估算/估算题/fit 行为面)、网申-笔试-案例面、up-or-out、exit options (退出路径: PE/VC/corp dev 企业发展/战略岗/创业/industry); (g) 争议/批判 — 咨询的

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Generate North American road-trip itineraries as a map-first, offline-friendly single-file HTML page. Plans around daily driving segments, overnight stops, fuel/EV-charging, national-park reservations (Recreation.gov / NPS), seasonal road closures, and timezone/border crossings — for executable, decision-ready trips. Two entry modes: give a start + region/destination + days and it plans the whole route, or hand it an existing route and it verifies, fills gaps, and produces the page.

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Collecting user feedback via NPS surveys, review analysis, sentiment analysis, feedback classification, and insight extraction reports. Use when establishing feedback loops.

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Expert customer lifecycle marketing guidance for retention, expansion, and advocacy. Use when designing onboarding programs, creating upsell strategies, preventing churn, building referral programs, or writing customer success content. Use for NPS programs, win-back campaigns, customer segmentation, and lifecycle email sequences.

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Strategic Customer Success leadership guidance for CS org design, customer segmentation and tiering (tech touch, low touch, high touch), success metrics and KPIs (NRR, GRR, NPS, CSAT, CES), playbook development, executive stakeholder management, CS technology stack strategy, value realization frameworks, and customer journey mapping. Use when building CS teams, defining customer segments, designing playbooks, measuring success outcomes, or implementing CS platforms.

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Structures customer diligence with interview guides, NPS analysis, switching cost assessment, and usage pattern evaluation. Use when conducting customer references, validating product-market fit, or assessing customer satisfaction.

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"Measure and optimize customer service performance using CSAT, NPS, CES, First Contact Resolution, and text mining on support tickets. Use this skill when the user needs to evaluate CS team performance, identify top complaint drivers, optimize staffing, or build CS dashboards — even if they say 'is our CS team doing well', 'what are customers complaining about', 'how many agents do we need', or 'build a CS dashboard'.".

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Analyze survey and feedback data with statistical distributions, cross-tabulations, significance testing, and open-ended theme extraction. Produces executive-ready survey reports with segment comparisons and action recommendations. Use when processing NPS, CSAT, employee engagement, or market research surveys.

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Analyze CSAT, NPS comments, reviews, and support feedback for sentiment, recurring themes, customer pain, and service improvement actions. Use for customer support and CX feedback reviews.

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Build a customer health scorecard across usage, engagement, adoption, NPS, support load, and financial risk. Use when user says "health score", "customer health", "build a scorecard", "how healthy is this account", "customer scoring model", "green yellow red", "health dashboard", or "account health framework" - even if they don't say "scorecard" explicitly. Applies to CSMs building account health models or CS leaders standardizing health tracking across the team.

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Use this skill when gathering, structuring, and documenting requirements for a Financial Services Cloud (FSC) wealth management implementation — including financial planning workflow discovery, portfolio review process mapping, client lifecycle requirements, advisor tooling needs, and FSC architecture determination (managed package vs. FSC Core). Trigger keywords: wealth management requirements, FSC requirements gathering, financial planning workflow, portfolio review process, advisor tools setup, FSC data model scoping, wealth management process mapping. NOT for implementation, configuration, or code — use financial-account-setup, fsc-action-plans, or apex/fsc-financial-calculations for those. NOT for FSC architecture decisions — use architect/wealth-management-architecture. NOT for Health Cloud or NPSP requirements.

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Use this skill when creating, configuring, or troubleshooting FSC Relationship Groups — including Household, Professional Group, and Trust group types; member role assignment via AccountContactRelation FSC fields; Primary Group designation; and group-level wealth aggregation rollups. NOT for standard account relationships, Contact-Account relationships outside FSC, NPSP household configuration, or Financial Account role setup (use admin/financial-account-setup).

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Call germline SNPs and indels with GATK HaplotypeCaller and the GVCF joint-genotyping workflow. Covers the local-reassembly + PairHMM mechanism (why HC beats pileup callers on indels), the -ERC GVCF reference-confidence model and <NON_REF> allele, BQSR-vs-DRAGSTR and --dragen-mode error modeling, allele-specific (AS_) annotations, and edge cases (ploidy, Mutect2 mitochondria mode, sex chromosomes/PAR, contamination gating). Use when deciding whether to use HaplotypeCaller vs a pileup or DRAGEN caller, whether BQSR still earns its place, whether to call per-sample GVCFs for a cohort, or how to handle non-diploid, mitochondrial, sex-chromosome, or contaminated samples. Not for post-calling filtering depth (see variant-calling/filtering-best-practices) or cohort joint-genotyping scaling (see variant-calling/joint-calling).

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Infers person-to-person transmission from pathogen genomes using outbreaker2, TransPhylo, phybreak, BadTrIP, SCOTTI, BEASTLIER, and SNP-distance / cluster-picker approaches (HIV-TRACE for HIV; transcluster). Defines outbreak clusters using pathogen-specific SNP thresholds (NOT a universal cutoff -- TB <=12 SNPs; MRSA <=15; C. difficile <=2; Klebsiella <=21), models within-host diversity and transmission bottlenecks, integrates contact-tracing data, distinguishes generation from serial interval, and attributes source via Bayesian source attribution (islandR). Use when investigating outbreaks for who-infected-whom, defining SNP-cluster outbreak definitions, accounting for unsampled intermediates, choosing between outbreaker2 (rich epi data) and TransPhylo (genomic-only after a dated phylogeny), running source attribution between host populations, calling HIV-TRACE thresholds appropriate to the local subtype, or distinguishing recent transmission from reactivation in TB or chronic HIV.

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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or Enformer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.

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Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.

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Focused Signals scout for PostHog projects running surveys. Watches active surveys for score regressions (NPS / CSAT / rating drops), response-volume drops, abandonment spikes, and targeting drift, AND aggregates open-text responses into recurring themes the team should know about (clusters of complaints, praise, feature requests). Emits findings only when a theme or anomaly clears the confidence bar; otherwise writes durable memory and closes out empty. Self-contained peer in the signals-scout-* fleet — no dependencies on other skills.

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Extract employee, employer, gross pay, INPS/IRPEF deductions, and net pay from Italian payslips.

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