「number」の検索結果

Query patent simple bibliographic (catalog) data from the Nexscope patent database. Triggered when users mention patent bibliographic information queries, patent basic info retrieval, patent catalog data, patent publication details, searching by patent number for inventors, patent applicant information, patent abstract retrieval, patent classification codes (IPC/CPC), patent citation queries, or any request to search for structured metadata by patent ID or publication number, patent brief bibliography, patent basic info, patent number lookup, patent abstract, Nexscope, or patent metadata. Even if the user does not explicitly mention "Nexscope" or "bibliographic info," this skill should be triggered whenever their need involves querying core bibliographic fields of specific patents.

日本語の概要は準備中です。原文の説明を表示しています。

Use when verifying information (fact, number, quote, event, statement) against authoritative primary sources, or cross-checking a number via one-level metric decomposition (Z = P × Q). Triggers: "verify X", "is this true", "find the original source", "where is this number from", "two sources disagree", "is it true X never did Y". Covers five scenarios: (1) basic truthfulness check, (2) completeness / out-of-context quoting, (3) one-level reasoning verification, (4) negative-statement handling, (5) multi-source conflict side-by-side output. Dig into whitelisted primary sources only (user-supplied files, official websites & databases, authoritative industry sources); cited reports / charts / datasets must be downloaded and read locally to count as verified — if download is blocked, hand the link to the user. If nothing can be found, plainly state "cannot verify" rather than guessing, patching, or citing secondary paraphrases. Always reply in the user's question language.

日本語の概要は準備中です。原文の説明を表示しています。

Number antibody variable domains, annotate CDRs, and assess developability from sequence. Use this skill to apply IMGT, Kabat, Chothia, Martin, or AHo numbering with ANARCI, delimit CDRs and framework regions, scan for chemical liabilities (N-glycosylation sequons, deamidation NG, isomerisation DG, oxidation, unpaired cysteine, fragmentation), compute pI, net charge, extinction coefficient and hydrophobicity, and plan humanisation by CDR grafting. Also trigger on antibody, nanobody, VHH, scFv, Fab, CDR, framework, ANARCI, abnumber, IgBLAST, OAS, SAbDab, humanization, Vernier residues, or developability.

日本語の概要は準備中です。原文の説明を表示しています。

Use when designing the systems of a game from a locked concept — core loops, meta loops, player verbs, progression, content systems, level structure, and narrative integration. Triggers on "game design doc", "GDD", "system spec", "core loop design", "progression design", "level design", "MDA", or "design the systems". Produces a design doc plus per-system specs that game-balancer numbers, iap-manager stocks, and godot-engineer builds. Stops at design — no number tuning, pricing, or engine code. For balance numbers see game-balancer; for the engine implementation see godot-engineer.

日本語の概要は準備中です。原文の説明を表示しています。

Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

日本語の概要は準備中です。原文の説明を表示しています。

Detect somatic and germline copy number variants from targeted, exome, and whole-genome sequencing with CNVkit, a read-depth caller that combines on-target and off-target (antitarget) coverage. Covers panel-of-normals construction, flat-reference tumor-only calling, hybrid/amplicon/WGS modes, CBS vs HMM segmentation selection, purity-aware integer calling, and reconciliation against GATK and allele-specific callers. Use when calling CNVs from hybrid-capture panels or exomes, deciding whether CNVkit (depth-only) is the right tool versus an allele-specific caller, building a panel of normals, diagnosing flat-reference false positives, or interpreting log2 ratios into copy-number states.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Create an implementation plan and a GitHub Issue based on the task description provided as an argument. Use this when the user supplies a natural-language task description (not an issue number) and wants a new implementation-ready Issue. If the input is an existing issue number, use create-issue-from-issue-number (re-analyze) or update-issue (reflect comments) instead.

日本語の概要は準備中です。原文の説明を表示しています。

Writes a DRAFT weekly KPI report from the figures the user pastes or attaches (this week, last week, optionally target and earlier weeks): a metrics table with change versus last week computed only from the stated figures, plain-language notes per metric, and numbered questions on every figure that moved more than the agreed threshold, crossed its target or broke its run. Use when the user asks to "write the weekly KPI report", "turn these numbers into this week's metrics report", "what changed versus last week", "draft the Monday numbers update" or "add commentary to this metrics table". Do not use for a recurring emailed report with a maintained trend sheet, use report-attachment-analyzer instead; for actuals versus budget, use budget-variance-explainer. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

Proposes the instrumentation and control content a P&ID adds to an accepted PFD process model: instruments drawn carried over as facts, measurement points and control loops the control philosophy requires, tag structure per the project instrument numbering procedure, system interfaces, and alarms, interlocks, trips and fail actions as quoted. Never assigns safety functions, ranges or setpoints. Use when the user asks to "run the instrumentation and control enrichment", "add the instrument section to the P&ID draft", "list the control loops the philosophy requires" or "carry the PFD instruments into the P&ID" after the piping section. Do not use for safety flags, SIL or trip classification, use process-safety-flags instead; do not use to assign tag numbers, use tagging-and-numbering. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

- Investigate a phone number — E.164 normalisation with libphonenumber, phoneinfoga scanning, carrier and line-type identification, VoIP and burner detection, messaging-app registration checks, and reverse-lookup and caller-ID sources.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end pooled and single-cell CRISPR screen analysis from FASTQ to hit genes. Orchestrates library design QC, guide counting, six-stage screen QC (plasmid Gini, replicate Pearson, CEGv2 PR-AUC, copy-number artifact), method-appropriate hit calling across MAGeCK RRA/MLE, BAGEL2, drugZ, JACKS, and Chronos, cancer-cell-line copy-number correction (CRISPRcleanR / Chronos), batch correction for multi-batch screens, and the specialized branches for combinatorial paralog screens, single-cell Perturb-seq, base-editor variant-function screens, prime-editor screens, and in vivo bottleneck-aware screens. Use when analyzing any pooled CRISPR screen end-to-end, matching the hit-calling method to the experimental design, integrating copy-number correction into the pipeline, or branching the workflow for single-cell, combinatorial, base-editor, prime-editor, or in vivo variants.

日本語の概要は準備中です。原文の説明を表示しています。

Create an implementation plan and a GitHub Issue based on the task description provided as an argument. Use this when the user supplies a natural-language task description (not an issue number) and wants a new implementation-ready Issue. If the input is an existing issue number, use create-issue-from-issue-number (re-analyze) or update-issue (reflect comments) instead.

日本語の概要は準備中です。原文の説明を表示しています。

Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

日本語の概要は準備中です。原文の説明を表示しています。

Detect somatic and germline copy number variants from targeted, exome, and whole-genome sequencing with CNVkit, a read-depth caller that combines on-target and off-target (antitarget) coverage. Covers panel-of-normals construction, flat-reference tumor-only calling, hybrid/amplicon/WGS modes, CBS vs HMM segmentation selection, purity-aware integer calling, and reconciliation against GATK and allele-specific callers. Use when calling CNVs from hybrid-capture panels or exomes, deciding whether CNVkit (depth-only) is the right tool versus an allele-specific caller, building a panel of normals, diagnosing flat-reference false positives, or interpreting log2 ratios into copy-number states.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Detect somatic and germline copy number variants from targeted, exome, and whole-genome sequencing with CNVkit, a read-depth caller that combines on-target and off-target (antitarget) coverage. Covers panel-of-normals construction, flat-reference tumor-only calling, hybrid/amplicon/WGS modes, CBS vs HMM segmentation selection, purity-aware integer calling, and reconciliation against GATK and allele-specific callers. Use when calling CNVs from hybrid-capture panels or exomes, deciding whether CNVkit (depth-only) is the right tool versus an allele-specific caller, building a panel of normals, diagnosing flat-reference false positives, or interpreting log2 ratios into copy-number states.

日本語の概要は準備中です。原文の説明を表示しています。

Calculate comprehensive numerology reports using Pythagorean or Chaldean systems. Supports English, Tamil, Telugu, Kannada, and Hindi. Use when a user wants numerology readings, life path numbers, destiny numbers, name analysis, birth date numerology, or lucky number calculations.

日本語の概要は準備中です。原文の説明を表示しています。

Get a disposable temp phone number and receive OTP codes to sign up on websites without using your real number. Handles x402 crypto payment automatically.

日本語の概要は準備中です。原文の説明を表示しています。

講座の計画から章・演習・問題・解答・解説のフォルダと説明ファイルのひな形を作り、命名規則やリンクを検査して教材づくりの土台を整えるスキル。

• 新しい講座の演習構成を作りたいとき
• 問題・解答・解説のひな形づくり
• 演習の改番と構成チェック

技術や設計を選んだ理由を、背景・比較案・影響とともにMarkdownへ記録するスキル。連番と索引で整理し、既存の記録から過去の判断理由も確認します。

• フレームワークやDBの選定理由の記録
• 設計の比較案と利点・欠点の整理
• 過去の技術判断の理由を調べたいとき

Establishes a project's quality bar as a written contract and stops agents quietly lowering it. Interviews the user on which dimensions matter, supplies sane default thresholds when they have no number in mind, records everything in CONSTRAINTS.md, and watches the diff for a weakened bar — new @ts-ignore or eslint-disable suppressions, skipped or deleted tests, assertions stripped out, unimplemented stubs, thresholds edited down. Use when no quality bar is written down, when the user says "set up constraints" or "define our standards", when the user wants dimensions they care about — accessibility, web performance, coverage — set up as enforced constraints, when an agent keeps silencing checks or skipping tests to get to green, when you need a coverage or performance threshold and don't know what number to pick, or when an agent writes more code than anyone will read.

日本語の概要は準備中です。原文の説明を表示しています。