「t cells」の検索結果

Image segmentation is the process of identifying the borders of individual objects (in this case cells) within an image. This allows for the features of cells such as marker expression and morphology to be extracted, stored and analysed. simpleSeg provides functionality for user friendly, watershed based segmentation on multiplexed cellular images in R based on the intensity of user specified protein marker channels. simpleSeg can also be used for the normalization of single cell data obtained f

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EBImage provides general purpose functionality for image processing and analysis. In the context of (high-throughput) microscopy-based cellular assays, EBImage offers tools to segment cells and extract quantitative cellular descriptors. Thi

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MHC (major histocompatibility complex) molecules are cell surface complexes that present antigens to T cells. The repertoire of antigens presented in a given genetic background largely depends on the sequence of the encoded MHC molecules, and thus, in humans, on the highly variable HLA (human leukocyte antigen) genes of the hyperpolymorphic HLA locus. More than 28,000 different HLA alleles have been reported, with significant differences in allele frequencies between human populations worldwide

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Risk & Compliance (GRC) Super Intelligence Team. Named real-world personas across 7 cells. Built local-first (LM Studio) and validator-gated. Illustrative composites; see DISCLAIMER.md.

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A **codescent object** is the 2-categorical analogue of a coequalizer. While coequalizers identify elements under an equivalence relation, codescent objects identify 1-cells under a coherent system of 2-cells. They are the fundamental tool for:

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Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.

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Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.

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Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervised label transfer, and Bayesian differential expression. Reach for this skill to integrate scRNA-seq batches, embed cells for clustering, transfer annotations from a reference onto a query, or score differentially expressed genes per cluster. For spatial deconvolution / mapping use the cell2location, DestVI, or Tangram methods instead.

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Cell type assignment from marker expression in IMC data. Covers manual gating, clustering, and automated classification approaches. Use when assigning cell types to segmented IMC cells based on protein marker expression or when phenotyping cells in multiplexed imaging data.

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Select QA-approved canonical intent cells into a versioned AI-visibility tracking panel with partitions, variants, lanes, surfaces, locales, repetitions, separate exposure and priority weights, randomization, uncertainty, refresh rules, and campaign controls. Use after prompt QA or when revising an existing panel.

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AUCell allows to identify cells with active gene sets (e.g. signatures, gene modules...) in single-cell RNA-seq data. AUCell uses the "Area Under the Curve" (AUC) to calculate whether a critical subset of the input gene set is enriched with

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A package for demultiplexing single-cell sequencing experiments of pooled cells labeled with barcode oligonucleotides. The package implements methods to fit regression mixture models for a probabilistic classification of cells, including multiplet detection. Demultiplexing error rates can be estimated, and methods for quality control are provided.

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Your legal, IP, and regulatory brain trust. 31 named personas across 7 cells covering patent strategy, tech licensing, regulatory litigation, AI governance, open-source compliance, privacy law, and antitrust.

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Your climate and energy brain trust. 25 named personas across 7 cells covering energy transition, carbon markets, climate modeling, sustainability, grid infrastructure, environmental policy, and ESG.

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Your healthcare and life sciences brain trust. 25 named personas across 7 cells covering drug discovery, medtech, biotech strategy, health policy, genomics, clinical trials, and healthcare economics.

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Your software-engineering brain trust. Named personas across 11 cells covering cloud architecture, reliability/SRE/observability, data and storage, security, FinOps, languages and runtimes, systems programming, web and frontend…

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Your finance brain trust and decision partner. Named personas across 7 cells: valuation/corporate finance, investing, accounting/FP&A, macro, fintech, behavioral, and capital markets/M&A/private. Markets/quant/derivatives are reserved for…

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Fill `outline/tables_index.md` from `outline/table_schema.md` + evidence packs (NO PROSE in cells; citation-backed rows).

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Multi-modal single-cell analysis with muon/MuData. Joint RNA+ATAC (10x Multiome), CITE-seq (RNA+protein), other multi-omics. MuData holds per-modality AnnData with shared obs. WNN joint embedding, per-modality preprocessing, MOFA factor analysis. Use scanpy-scrna-seq for single-modality RNA; use muon when combining 2+ omics from the same cells.

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Select, install, and name the authoritative compiler, simulator, solver, or other external verifier for an Anabasis harness. Use when deciding which practitioner tool to trust, writing the truth check that runs it, or diagnosing verifierUnavailable, timeout, crash or sandbox results. Also owns the install probe, the executable board for what the Builder can install and run behind the real cells and wall. Use harness-contract (discrimination proof) for semantic accept/reject coverage.

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Detect cell-ordering / enchainement problems in Jupyter notebooks (canonical-order slippage, misplaced or forgotten cells). Arguments: [target] [--severity HIGH|MED|LOW] [--json]

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Expert-level developmental biology covering embryogenesis, cell fate determination, morphogen gradients, organogenesis, stem cells, and regenerative medicine.

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Research one agent harness's release (docs, source, runtime) and fill its capability cells in scripts/harness_capabilities.py with cited evidence. Use after a harness version bump, when just harness-probe reports re-research, or when capability cells read unknown.

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Excel (.xlsx) manipulation via MCP server. Use for creating workbooks, formatting cells, writing formulas, building charts, pivot tables, data analysis, or any task involving Excel spreadsheets.

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