789 件 ・ 関連度順
概要と使いどころ
Evaluate LLM outputs using frontier models as judges. Use for pairwise model comparison, quality scoring with custom rubrics, and automated evaluation pipelines. Covers position bias mitigation, statistical significance, and generating preference data for DPO/RLHF.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end small RNA-seq analysis from FASTQ to differential miRNA expression and target prediction. Use when analyzing miRNA, isomiR, tRF, or piRNA sequencing data through preprocessing, quantification, discovery, DE, and targets.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end proteomics workflow from MaxQuant output to differential protein abundance. Orchestrates data import, normalization, imputation, and statistical testing with limma (default) or MSstats for complex feature-level designs. Use when processing mass spectrometry proteomics.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end bisulfite sequencing workflow from FASTQ to differentially methylated regions. Covers Bismark alignment, methylation calling, and DMR detection with methylKit. Use when analyzing bisulfite sequencing data.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end alternative splicing analysis from FASTQ to differential splicing results for short-read bulk RNA-seq. Aligns with STAR 2-pass cohort-style, performs junction QC (RSeQC, MaxEntScan, SpliceAI), runs rMATS-turbo and leafcutter for concordant differential analysis, optionally MAJIQ V3 for complex events / heterogeneous cohorts, isoform-switching with NMD/ORF/domain consequences (IsoformSwitchAnalyzeR v2 + DRIMSeq+DEXSeq+stageR DTU), and sashimi visualizations. Use when performing comprehensive splicing analysis from raw bulk RNA-seq data; for variant-driven splice prediction see splice-variant-prediction; for rare-disease single-patient outlier detection see outlier-splicing-detection; for full-isoform PacBio/ONT analysis see long-read-splicing.
日本語の概要は準備中です。原文の説明を表示しています。
Orchestrates an end-to-end CRISPR editing experiment design from target gene to delivery-ready, validatable constructs. Sequences guide design, off-target assessment, edit-modality selection (knockout, base editing, prime editing, HDR knock-in), and template/donor design, with a QC checkpoint at each handoff. Use when designing a complete CRISPR experiment for knockout, point correction, or tagging and the order of operations, the modality decision, and the cross-cutting traps are needed rather than a single step. Defers each step's mechanics to the genome-engineering skills.
日本語の概要は準備中です。原文の説明を表示しています。
Orchestrates an end-to-end de novo genome assembly project, routing each step to the right genome-assembly skill rather than restating it. Profiles the genome first (k-mer spectrum -> size, heterozygosity, ploidy), QCs reads, chooses an assembly path by data type (SPAdes for Illumina, Flye for noisy long reads, hifiasm for HiFi, metaFlye for communities), polishes only when needed, decontaminates, scaffolds with Hi-C, and finishes with three-axis QC (contiguity + completeness + correctness). Use when assembling a genome from raw reads and deciding which assembler, whether to polish, and how to prove the result is good.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end Hi-C analysis workflow from FASTQ to compartments, TADs, and loops, with the decision of WHICH features the sequencing depth can support. Covers pairtools read-pair processing and library QC, cooler matrices, ICE balancing and distance-decay expected, A/B compartments, TAD boundaries, loop calling, and the routing of HiChIP/PLAC-seq/Capture Hi-C to protein-directed loop callers. Use when processing Hi-C data end to end, deciding a resolution for a given depth, or choosing between bulk-Hi-C and protein-directed loop calling.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end genome-scale metabolic modeling from genome sequence to flux predictions. Covers automated reconstruction with CarveMe, model validation with memote, FBA/FVA analysis, and gene essentiality prediction. Use when building metabolic models or predicting metabolic phenotypes from genomic data.
日本語の概要は準備中です。原文の説明を表示しています。
Authors reproducible bioinformatics pipelines with Snakemake - rules wired by output-file pattern, wildcards and expand() for sample fan-out, checkpoints for runtime-unknown outputs, resource/retry escalation, and conda/container software deployment on HPC and cloud. Use when deciding rule-based (Snakemake) vs channel/dataflow (Nextflow) authoring; wiring rules by OUTPUT-file pattern rather than imperative order; using wildcards + expand() for sample fan-out and constraining them to stop silent mis-routing; adding checkpoints when the set of outputs is unknown until a step runs (dynamic DAG); diagnosing why a job reran (or did not) under the mtime-plus-provenance trigger set; escalating memory on retry for OOM-killed jobs; and porting a Snakemake 7 `--cluster`/remote-provider command to the Snakemake 8+ executor-plugin and storage-plugin model (snakemake-executor-plugin-slurm) with `--software-deployment-method`.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end imaging mass cytometry workflow from raw acquisitions to spatial cell analysis. Orchestrates image preprocessing, segmentation, phenotyping, and spatial statistics. Use when analyzing imaging mass cytometry data end-to-end.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end copy number variant detection workflow from BAM files. Covers CNVkit analysis for exome/targeted sequencing with visualization and annotation. Use when detecting copy number alterations from sequencing data.
日本語の概要は準備中です。原文の説明を表示しています。
Authors bioinformatics pipelines in WDL (Workflow Description Language) run by Cromwell or miniwdl, targeting the GATK/Broad and Terra/AnVIL/BioData Catalyst cloud ecosystem, with tasks, workflows, scatter-gather parallelism, structs, and a runtime block that sizes the cloud VM. Use when deciding to target Terra/AnVIL/GATK/WARP (chosen for the ecosystem, not the language); sizing runtime disks dynamically for a fresh-per-task cloud VM (ceil(size(f)*factor)+buffer); choosing preemptible vs on-demand VMs by task length and idempotency; picking Cromwell (production, cloud, call-caching) vs miniwdl (local dev, miniwdl check linting, readable errors); enabling and debugging call-caching silent-miss modes; pinning Docker by digest for reproducibility and cache stability; or scattering an array for parallel fan-out.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end ChIP-seq workflow from FASTQ files to annotated peaks. Covers QC, alignment, peak calling with MACS3 (or HOMER), and peak annotation with ChIPseeker. Use when processing ChIP-seq data from alignment through peak annotation.
日本語の概要は準備中です。原文の説明を表示しています。
Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.
日本語の概要は準備中です。原文の説明を表示しています。
Extract invoice data and generate a formatted PDF summary in a single pipeline.
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Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.
日本語の概要は準備中です。原文の説明を表示しています。
Provides integration patterns for LangChain4j with Spring Boot. Configures AI model beans, sets up chat memory with Spring context, integrates RAG pipelines with Spring Data, and handles auto-configuration, dependency injection, and Spring ecosystem integration. Use when embedding LangChain4j into Spring Boot applications, building Java LLM applications with @Bean configuration, or setting up Spring AI patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Azure Machine Learning SDK v2 for Python. Use for ML workspaces, jobs, models, datasets, compute, and pipelines.
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Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment. Use when creating data pipelines, orchestrating workflows, or scheduling batch jobs.
日本語の概要は準備中です。原文の説明を表示しています。
Create, implement, deploy, and debug Adobe Runtime actions with consistent layout, validation, and error handling. Use this skill whenever the user needs to add actions to an App Builder project, understand action structure (params, response format, web/raw actions), configure actions in the manifest, use App Builder SDKs (State, Files, Events, database), deploy and invoke actions via CLI, debug action issues, or implement patterns such as webhook receivers, custom event providers, journaling consumers, large payload redirects, action sequence pipelines, and Asset Compute workers. Also trigger when users mention serverless functions in Adobe context, action logging, IMS authentication for actions, or cron-style scheduled actions.
日本語の概要は準備中です。原文の説明を表示しています。
武將數值平衡調校 SKILL — 以雙軸演算法（maxStat + avg5）自動計算 rarityTier 與 characterCategory，並執行 EP 重算、適性校驗、因子分派、稀有度分布統計。USE FOR: 新武將入庫前的數值校準、全量武將的平衡盤點、稀有度自動分類。DO NOT USE FOR: 故事生成（用 general-story-writer）、資料爬取匯入（用 general-data-pipeline）。
日本語の概要は準備中です。原文の説明を表示しています。
武將資料管線 SKILL — 整合「公開資料爬取 → 欄位映射 → 合併去重 → 自動分類 → 品質驗證 → 匯出入庫」的端到端流程。USE FOR: 批次新增武將、從光榮三國志 Wiki 匯入參考數值、建立 master 資料集。DO NOT USE FOR: 故事文案生成（用 general-story-writer）、細部數值微調（用 general-balance-tuner）。
日本語の概要は準備中です。原文の説明を表示しています。
通用任務開單器 SKILL — 統一建立或回寫 Markdown task card、docs/tasks/tasks-*.json 分片、UI quality shard，並強制遵守 docs/agent-briefs/Readme.md (doc_ai_0023) 與 docs/遊戲規格文件/系統規格書/名詞定義文件.md (doc_spec_0008) 的硬規則。USE FOR: 開任務卡、開單、task card、task shard、tasks-ui.json、tasks-prog.json、tasks-dc.json、tasks-data.json、agent-briefs/tasks、docs/tasks/*_task.md、UI pipeline 開卡。DO NOT USE FOR: 純 runtime 除錯、單純修改既有功能碼但不需要新卡、只做極小 typo 修補。
日本語の概要は準備中です。原文の説明を表示しています。