「line art」の検索結果

Scope, preregister, execute, audit, normalize, and publish GEODE evaluations with research-question, reproduction, attempt-lineage, trajectory, verifier-receipt, and immutable artifact contracts. Use for benchmark runs or comparisons, eval-artifact and cache-accounting audits, GPT or subscription result normalization, research question or hypothesis framing, retry diagnosis, trajectory publication, DPO or reward-data readiness reviews, and requests involving MCPMark, tau2, BFCL, Agent-World, HAL, Terminal-Bench, or Toolathlon.

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Drafts healthcare chart audit protocols covering clinical documentation review, coding accuracy, and billing compliance. Aligns with Medicare CoPs, OIG Compliance Program Guidance, RAC preparedness, federal sentencing guidelines, and the 60-day overpayment rule. Use when drafting routine periodic audits, targeted risk reviews, proactive compliance measures, or post-regulatory-update assessments.

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Manages Rule 30(b)(6) corporate representative deposition workflows — drafting notice topics with reasonable particularity, building examination outlines, defending designees, handling objections, and preserving binding admissions for summary judgment or trial. Use when drafting or responding to 30(b)(6) notices, selecting and preparing designees, building topic-by-topic outlines, or triaging scope and privilege disputes. Trigger keywords: 30(b)(6), corporate representative deposition, topic list, designee, notice analysis, deposition objections, corporate admissions.

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Expert in turning data visualizations into compelling video and animation content for social media and marketing. Activate on: data commercial, animated chart, data storytelling video, chart animation, Remotion data video, Motion Canvas, Flourish animation, D3 animation, data viz social media, dashboard recording, data narrative video. NOT for: static data visualization (use data-viz-2025), general video editing (use video-processing-editing), full video production pipeline (use ai-video-production-master).

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Spark, pandas, polars, DuckDB optimization for batch data processing. Activate on: batch processing, Spark optimization, polars, DuckDB, pandas performance, data frame, shuffle, partition, memory optimization. NOT for: streaming pipelines (use streaming-pipeline-architect), warehouse queries (use data-warehouse-optimizer).

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Verifies build output integrity after code changes. Runs builds, validates artifact structure, checks for regressions in bundle size, asset references, and static export completeness. The last line of defense before a bad deploy ships.

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Expert in script-to-video production pipelines for Apple Silicon Macs. Specializes in hybrid local/cloud workflows, LoRA training for character consistency, motion graphics generation, and artist commissioning. Activate on 'AI video production', 'script to video', 'video generation pipeline', 'character consistency', 'LoRA training', 'cloud GPU', 'motion graphics', 'Wan I2V', 'InVideo alternative'. NOT for real-time video editing, video compositing (use DaVinci/Premiere), audio production, or 3D modeling (use Blender/Maya).

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Create inline Mermaid v11 diagrams -- flowcharts, sequence, class, ER, Gantt, state, timeline, and more -- for markdown and browser. Zero deps; mmdc optional for CLI export.

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Use when a plan directory (plan.md + phase-*.md) needs a visual review. By DEFAULT this drives the STRUCTURED visual-plan artifact (visual-plan/plan.json) via the mewkit visual-plan CLI — generate if absent, validate, open the local studio (view/edit), and export plan.html from the approved artifact. Pass --static for the legacy prompt-only single-file plan.html template render. Triggers on "render this plan", "visualize the plan", "open the plan studio", "make a shareable plan page", "plan.html". This is the canonical owner of plan-as-visual-review. NOT for plan critique or scope review (see mk:plan-ceo-review / mk:validate-plan), NOT for generic code/diagram/diff visuals (see mk:preview), NOT for live media generation (see mk:multimodal).

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Generate publish-grade SVG+PNG technical diagrams — architecture, data flow, flowchart, sequence, agent-memory, class, ER, state-machine, comparison, timeline, and more — across 8 visual styles. Writes output to tasks/visuals/ or an active plan's visuals/ directory. Requires rsvg-convert (librsvg) for PNG export; degrades gracefully to SVG-only when absent.

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Create diagrams and visualizations using Mermaid.js v11 syntax. Use when generating flowcharts, sequence diagrams, class diagrams, state diagrams, ER diagrams, Gantt charts, user journeys, timelines, architecture diagrams, or any of 24+ diagram types. Supports JavaScript API integration, CLI rendering to SVG/PNG/PDF, theming, configuration, and accessibility features. Essential for documentation, technical diagrams, project planning, system architecture, and visual communication.

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Initialize or safely upgrade a processor project's root AGENTS.md from a maintained baseline. Use when starting a processor project, adding project-level Agent collaboration rules, or comparing an existing AGENTS.md with the package baseline. This skill only handles AGENTS.md; it does not scaffold documentation, inspect or configure environments, install tools, or modify processor source.

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Normalize read-depth copy-ratio profiles and segment them into copy-number regions using circular binary segmentation (CBS, DNAcopy), hidden Markov models, HaarSeg, and fused-lasso methods. Covers GC-content, mappability, and replication-timing (wave-artifact) bias correction, panel-of-normals/PCA denoising, diploid-baseline centering, and algorithm selection by sequencing depth and event size. Use when choosing a segmentation algorithm, correcting depth bias, diagnosing oversegmentation or a mis-centered baseline, tuning CBS or HMM parameters, or understanding why a downstream CNV caller produced fragmented or shifted segments.

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Analyzes base-editing screens for variant function. Covers library design (Hanna 2021 ClinVar-scale CBE screen benchmarked on BRCA1/2, Cuella-Martin 2021 DDR saturation), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end; 4-7 for ABE7.10), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit calling, indel byproduct interpretation, the substitution-vs-indel diagnostic, variant annotation against ClinVar / COSMIC, and the Broad be-validation-pipeline. Use when designing a BE variant screen, choosing CBE vs ABE for a specific edit, interpreting bystander-confounded hits, distinguishing functional signal from indel artifact, integrating CRISPResso2 output with screen scoring, or deciding BE vs PE for SNV installation.

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Detect introgression and admixture between species or populations using Dsuite (Malinsky 2021 fast D-statistics), Patterson's D / ABBA-BABA test (Green 2010; Durand 2011), f4-ratio and f-branch statistic (Malinsky 2018), TreeMix (Pickrell & Pritchard 2012), HyDe (Blischak 2018), QuIBL (Edelman 2019), sprime (Browning 2018), Twisst (Martin 2017), PhyloNet (Than 2008) for explicit phylogenetic networks, and qpAdm / qpGraph (Patterson 2012). Distinguish introgression from incomplete lineage sorting (ILS), ancestral structure, ghost-lineage admixture, and rate variation. Use when testing inter-species gene flow, dating admixture events, identifying introgressed segments, building phylogenetic networks for reticulate evolution, or applying the ABBAclustering (Koppetsch-Malinsky-Matschiner 2024) framework for divergent-species gene flow.

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Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the gene-independent DNA-damage / G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

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Recommends checking and managing vitamin D according to Endocrine Society guidelines to avoid hypocalcemia in patients receiving bisphosphonates or denosumab for hypercalcemia of malignancy. Use when a clinician notes risk factors for hypocalcemia (e.g., low 25‑OH vitamin D, renal insufficiency) and asks about baseline labs before antiresorptive start.

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Recommends spironolactone as first-line mineralocorticoid receptor antagonist for initial medical therapy of primary aldosteronism due to low cost and widespread availability. Use when a clinician queries which MRA to start for a patient with PA requiring medical therapy.

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In central hypothyroidism patients receiving levothyroxine who initiate enzyme‑inducing antiepileptic drugs, the guideline recommends checking free T4 at least 6 weeks after AED start and increasing the levothyroxine dose if free T4 falls below the target range. Triggers include: central hypothyroidism patient on levothyroxine starting antiepileptic drug such as phenytoin, carbamazepine, or oxcarbazepine.

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Read-only release + backlog recap. Reports the last release, commits-since-tag classified by conventional-commit type with the semver bump they trigger and pushed-vs-origin state, the backlog bucketed (open/picked-up/dropped with epic parent→child nesting), the roadmap epics with their per-task tallies, and condensed open questions — then recommends the next pickup. One `cli.mjs recap` call returns all six recap keys. Invoke any time (on demand) to plan a release or choose the next thing to build; a compact form is also surfaced at session start. Not a workflow phase; never writes CHANGELOG; never starts or commits work.

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Read-only view of the execution roadmap. Lists every epic with its per-status tallies, nests the still-open rows beneath their epic, collapses wholly-finished epics into one rollup line, and closes by naming the next planned task in file order. Four verbs — `list` (the reader's view), `tasks` and `epics` (filterable row and epic queries), `next` (the first planned task). Invoke any time to see what is left to build. Not a workflow phase; never writes; never starts or commits work.

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Review the auto-extracted candidates in `.claude/memory/_pending.md` and commit keepers to the canonical memory files (`landmarks.md`, `libraries.md`, `decisions.md`, `landmines.md`, `conventions.md`, `pending-questions.md`, `backlog.md`). Invoke at session start when the SessionStart hook reports pending candidates, or any time `_pending.md` has accumulated entries you want to curate. Reset the pending body after flushing.

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EXPERIMENTAL. Join or leave an org-team coordination channel as a session peer. `/companion on <channel_id> [peer_id]` registers this Claude Code session as a `pclass:"session"` peer and works the claim → execute → signal loop, escalating un-decidable forks to the lead (never deciding). `/companion off` deregisters. `/companion status` reports the current peer. Part of org mode (Article X), which is opt-in via `velocity.org_mode.enabled` and OFF by default. Use when a human launches a second session to act as a peer alongside a lead.

日本語の概要は準備中です。原文の説明を表示しています。