「cro」の検索結果

Use when a task needs the judgment of a CEO/chief executive — setting company strategy, allocating scarce resources (capital, headcount, attention) across competing priorities, making a call that only the top of the org can make, or communicating direction to the board, investors, or the whole company.

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Use when a task needs the judgment of a Butcher/Meat Cutter — computing true cost per sellable pound from a primal's actual cutting yield, allocating a primal's cost across cut categories by relative market value, pricing dry-aged product against its finished (not green) weight, or diagnosing whether a below-average yield traces to cutting spec rather than the animal itself.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task needs the judgment of a Chief Data Officer — resolving conflicting metric definitions across dashboards, deciding whether a dataset should be retained or purged, assigning data ownership for a system feeding regulatory or board reporting, sizing a privacy/breach risk against a proposed data collection, or auditing data readiness before an AI/ML initiative kicks off.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task needs the judgment of a brokerage clerk — resolving a trade-break/reconciliation exception before settlement, recomputing a weighted-average execution price across partial fills, processing a corporate action's effect on share count and cost basis, or responding to a DK (don't-know) notice from a contra broker.

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Use when a task needs the judgment of an atmospheric scientist/operational meteorologist — interpreting ensemble forecast guidance, deciding whether conditions cross a severe-weather warning threshold, calibrating a raw model probability against verification climatology, or writing a forecast discussion or warning product under time pressure.

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Use when a task needs the judgment of an Art Director — commissioning and choosing between divergent creative concepts for a campaign, triaging client feedback into concept vs. execution notes, pressure-testing a concept against a production budget/timeline before it's locked in, or managing a shoot/production budget across a multi-deliverable campaign.

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Use when a task needs the judgment of an avionics technician — chasing an intermittent nav/comm or autopilot fault that "checks good" on the ground, deciding whether an avionics upgrade needs an STC or qualifies for field approval, verifying bonding resistance and wire-bundle separation on an install, cross-checking a new LRU's DO-160 environmental qualification against its install location, or writing an avionics discrepancy/return-to-service entry.

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Use when a task needs the judgment of a billing and posting clerk — generating an invoice against a rate/contract schedule, applying an incoming payment across multiple open invoices, processing a credit memo or adjustment, or investigating an aging-report discrepancy.

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Use when a task needs the judgment of a Bartender — reconciling actual pour cost against theoretical liquor cost by drink category, deciding whether and how to cut off a guest, pricing a drink menu across well/call/premium tiers, closing out a till and comp log at shift end, or sequencing bar-top service against a backed-up service well.

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Use when a task needs the judgment of an Area, Ethnic, or Cultural Studies Professor — designing a joint-appointment course load across two departments, prepping a tenure or mid-tenure review file for interdisciplinary scholarship, deciding whether a course survives an enrollment or political-pressure threat, evaluating community-engaged research for a merit case, or writing a Title VI/FLAS-adjacent grant narrative.

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Use when a task needs the judgment of a tenure-track or tenured Agricultural Sciences faculty member at a land-grant university — deciding whether to submit a grant this cycle versus wait, allocating time across the teaching/research/extension appointment split, diagnosing a stalled graduate student or field trial, or drafting a tenure-and-promotion dossier narrative.

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Use when a task needs the judgment of an Agricultural Inspector — grading a lot of produce against a USDA grade standard's defect tolerances, evaluating agricultural water test results against FSMA microbial thresholds, checking a pesticide residue result against the commodity-specific EPA tolerance, deciding whether a finding warrants a stop-sale order versus a corrective-action letter, or verifying a facility's traceability records against a recall deadline.

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Use when a task needs the judgment of an Agricultural Equipment Operator — calibrating planter seed population and singulation, diagnosing combine header or separator loss, sequencing planting or harvest across fields under a weather-constrained window, sizing machinery capacity in acres/hour against a season's acreage, or evaluating PTO/grain-bin entrapment safety on a job site.

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Use when a task needs the judgment of a Farmer, Rancher, or other Agricultural Manager — deciding a planting/breeding mix or acreage shift under price and weather uncertainty, sizing a hedge or crop-insurance coverage level, running break-even and diversification scenarios before a capital or input commitment, or evaluating land/herd management practices against long-term productive capacity.

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Use when a task needs the judgment of an aircraft service attendant — servicing an aircraft's potable water or lavatory/waste system without cross-connecting the two, sequencing turnaround tasks inside a fixed gate-time window, staging ground support equipment around an active aircraft, or timing servicing against a deicing/anti-icing holdover-time window before pushback.

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Use when a task needs the judgment of an Architectural and Civil Drafter — setting up a CAD sheet at the correct scale and viewport scale factor, applying NCS/AIA layer and sheet-numbering standards, dimensioning a wall assembly or site plan per governing convention, managing xrefs and revision clouds across a sheet set, or QC-checking a drawing set before issuance.

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Guide for multi-experiment batch operations: QC screening, batch download, comparison, and report generation across many ENCODE experiments simultaneously. Use when users need to process 5+ experiments together, create experiment comparison tables, perform batch quality checks, or generate summary reports. Trigger on: batch analysis, multiple experiments, bulk processing, experiment comparison, batch QC, multi-sample, batch download, experiment table, summary report, collection analysis.

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Evaluate ENCODE experiment quality using standard metrics and audit flags. Use when the user asks about data quality, wants to filter for high-quality experiments, needs to interpret quality metrics (FRiP, NSC, RSC, NRF, IDR, TSS enrichment, fragment size), wants to understand ENCODE audit warnings, needs to compare quality across experiments, or is deciding whether data is usable for their analysis. Also use when the user mentions QC, quality control, or data filtering.

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Convert genomic coordinates between assembly versions (GRCh37/hg19 to GRCh38/hg38, mm9 to mm10). Guides UCSC liftOver for BED files, CrossMap for VCF/bigWig, and handles unmapped regions with provenance logging.

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Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and which transcription factors control them?" by layering expression, chromatin accessibility, histone marks, and TF binding data. Follows the Mawla et al. 2023 framework for cross-assay integration of islet cell type-specific data. Handles chromatin state annotation (ChromHMM), enhancer-gene linkage, TF motif enrichment, and cell type-specific regulatory element identification. Use for ANY multi-omic analysis, enhancer discovery, regulatory network construction, or epigenomic characterization using ENCODE data.

日本語の概要は準備中です。原文の説明を表示しています。

Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs bulk profiles. Covers platform differences (10X Chromium, Smart-seq2, Drop-seq), quality limitations of single-cell data, multimodal integration (RNA+ATAC), and cross-study reproducibility concerns. Also use for cell type annotation, gene detection limits, dropout artifacts, and single-cell data structure in ENCODE.

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Build comprehensive epigenomic profiles for tissues or cell types using ENCODE data. Use when the user wants to characterize chromatin states, assemble histone modification panels, create epigenomic landscapes, run ChromHMM segmentation, identify super-enhancers or bivalent domains, profile regulatory elements across a biosample, or understand epigenetic regulation in a specific biological context. Covers histone marks, chromatin accessibility, TF binding, transcription, DNA methylation, and 3D genome structure.

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Expert guidance for Domain-Driven Design architecture and implementation. Use when designing complex business systems, defining bounded contexts, structuring domain models, choosing between modular monolith vs microservices, implementing aggregates/entities/value objects, or when users mention "DDD", "domain-driven design", "bounded context", "aggregate", "domain model", "ubiquitous language", "event storming", "context mapping", "domain events", "anemic domain model", strategic design, tactical patterns, or domain modeling. Helps make architectural decisions, identify subdomains, design aggregates, and avoid common DDD pitfalls.

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Use when starting any conversation - establishes how arkhe skills bootstrap on Claude Code, Antigravity CLI (agy) / Gemini CLI, and Codex CLI, and maps Claude-only tools (AskUserQuestion, TaskCreate, EnterPlanMode, the Skill tool, the Agent tool) to their cross-platform equivalents

日本語の概要は準備中です。原文の説明を表示しています。