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概要と使いどころ
Defines an S4 class for storing data from spatial -omics experiments. The class extends SingleCellExperiment to support storage and retrieval of additional information from spot-based and molecule-based platforms, including spatial coordina
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Provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported.
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Gene Set Variation Analysis (GSVA) is a non-parametric, unsupervised method for estimating variation of gene set enrichment through the samples of a expression data set. GSVA performs a change in coordinate systems, transforming the data fr
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PhIPData defines an S4 class for phage-immunoprecipitation sequencing (PhIP-seq) experiments. Buliding upon the RangedSummarizedExperiment class, PhIPData enables users to coordinate metadata with experimental data in analyses. Additionally, PhIPData provides specialized methods to subset and identify beads-only samples, subset objects using virus aliases, and use existing peptide libraries to populate object parameters.
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Defines a S4 class for storing data from single-cell experiments. This includes specialized methods to store and retrieve spike-in information, dimensionality reduction coordinates and size factors for each cell, along with the usual metada
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R generic interface to Hi-C contact matrices in `.(m)cool`, `.hic` or HiC-Pro derived formats, as well as other Hi-C processed file formats. Contact matrices can be partially parsed using a random access method, allowing a memory-efficient representation of Hi-C data in R. The `HiCExperiment` class stores the Hi-C contacts parsed from local contact matrix files. `HiCExperiment` instances can be further investigated in R using the `HiContacts` analysis package.
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国内自媒体发布前风险自审与保意修复：审口播稿、文章、图文笔记、字幕、封面文字能不能发抖音/小红书/微信视频号，给出具体位置、依据和可直接替换的改稿；被限流/删除/处罚后帮你复盘归因；你的行业敏感词、误报白名单和踩坑案例会沉淀成个人规则库，越用越准。Use when 用户说"能不能发""审一下稿子""查违禁词/敏感词""会不会限流/被限流了""帮我改成能发的版本""发布前检查""被平台处罚/删除了""帮我盯着这个词""导入违禁词表"。Not for 海外平台(X/YouTube)内容审核、起号涨粉策略、写稿创作本身。
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Names 2 other right-fit people at the prospect's own company so an email can ask "is this you or them?" without ever naming the person being emailed. Triggers on "name two other people at the company", "who else works there", "should I be talking to someone else", "colleague name variable", "other prospects line", "wrong person CTA". Outputs other_prospects, a ready-to-drop phrase like "Jeff Barg or Rob Cook".
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Coordinate all skills to build a complete advertising campaign. Trigger on "build a campaign", "full funnel", "ads + funnel".
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Cooperatively pause unfinished work in the current session, leave a precise continuation checkpoint, and resume from it when the user later says continue. Use only when the user explicitly requests this pause workflow. Do not use for crashes, app shutdown, new-session handoffs, or ordinary task summaries.
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Cialdini's seven principles of compliance (the classic six — reciprocation, commitment-consistency, social proof, liking, authority, scarcity — plus Unity, added 2016) and Pre-Suasion. Use when crafting ethical persuasion (marketing, sales, negotiation), defending against manipulation, or designing systems that need cooperation. Includes replication-crisis caveats and known factual corrections (Bickman parking-meter numbers, Hofling modern replication, Drive Carefully condition disambiguation, Genovese myth).
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TypeSafe AI（typesafe.ai）官方文档离线 Wiki，覆盖 Jev System One 模型、Choice/Score/Noul 问题原语、state 结构与置信度、架构 Patterns、Python/JavaScript SDK、HTTP API 参考与 Cookbooks 示例；用于查询 TypeSafe API/SDK 的接入、用法与示例。不用于其他 LLM 厂商 API、千问或百炼系列文档问题。
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Find affiliate programs in the OpenAffiliate registry, then confirm every term on the brand's own page and report each one with a verbatim quote and its source URL. Use this skill when the user wants affiliate terms they can rely on: before signing up, before publishing a review or comparison, when a listing looks outdated, or when two sources disagree. Also trigger for: "verify this affiliate program", "is X's affiliate commission still 30%", "what's the cookie length for X", "check the affiliate terms", "does X have an affiliate program", "find a recurring program and confirm the terms", "is this commission rate real", "source for X's affiliate terms", "fact-check this affiliate program", "what does X pay affiliates".
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Live affiliate program data from openaffiliate.dev. Search programs, compare commissions, check cookie days, find top performers. Use when researching affiliate programs, comparing options, or checking program details. Persistent daemon with cache — first call starts server (~2s), subsequent calls ~100ms.
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Research and evaluate affiliate programs to find the best ones to promote. Use this skill when the user asks anything about finding affiliate programs, comparing commission rates, evaluating affiliate opportunities, searching for products to promote, picking a niche, or mentions openaffiliate.dev. Also trigger for: "which SaaS should I promote", "best affiliate programs for X", "high commission programs", "recurring commission affiliate", "compare these affiliate programs", "is X affiliate program worth it", "find me something to promote", "what pays the most", "affiliate programs with long cookie duration".
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Search Atlas Obscura for weird, wonderful, and hidden gem places near any destination. Find the interesting stuff, not boring plaques. Search by coordinates, get full details with descriptions and images.
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Orchestrate the full PaperOrchestra (Song et al., 2026, arXiv:2604.05018) five-agent pipeline to turn unstructured research materials (idea, experimental log, LaTeX template, conference guidelines, optional figures) into a submission-ready LaTeX manuscript and compiled PDF. TRIGGER when the user asks to "write a paper from my experiments", "turn this idea and these results into a paper", "generate a conference submission", "run paper-orchestra on X", or otherwise wants the end-to-end paper-writing pipeline. Coordinates the outline-agent, plotting-agent, literature-review-agent, section-writing-agent, and content-refinement-agent skills.
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Use when building any Flutter screen or component to choose responsive Row, Column, Expanded, Flexible, and Spacer layouts before fixed-size or coordinate-based alternatives.
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Use when warm audiences need a plan — retargeting tiers by intent and recency, a different message per tier, frequency caps, attribution windows, lookalike seeds, exclusion rules, and a first-party data base that survives iOS ATT and cookie deprecation. Trigger on 'retargeting', 'remarketing', 'warm audience', 'custom audience setup', 'retarget cart abandoners', 'my retargeting pool is too small'. Also use when the user says people visit once and never come back. Not for — cold prospecting audiences, see `51-audience-research-global`; the pixel and events that feed these audiences, see `53-tracking-setup-global`; email win-back flows, see `14-email-marketing-global`; raising budgets, see `55-scaling-ads-global`.
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Collect auditable public X/Twitter posts by controlling the user's already logged-in Chrome, searching X's rendered web interface, scrolling visible results, and extracting original post text and metadata from DOM into normalized JSONL. Use for VOC research, social listening, multilingual keyword discovery, competitor monitoring, or historical search when X requires the user's browser session and cookies, credentials, internal GraphQL, paid APIs, or search-engine snippets must not be exported or used. X data layer of the bggg VOC suite (shared project folder; orchestrated by industry-orchestrator, reported by bggg-voc-report).
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使用 GLM 库实现 Vector3TransformNormal 和 Vector3TransformCoord 函数，模拟 DirectXMath 的行为，并使用 const T& 模板参数以支持多种向量类型。
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EU 사용자 대상 서비스용 Privacy Notice·Terms of Service·Consent Modal·Cookie Banner 자동 생성. GDPR (Regulation 2016/679) + ePrivacy Directive + Consumer Rights Directive 2011/83 + Digital Services Act + Digital Content Directive + Unfair Terms Directive 반영. 영문 인터뷰로 진행.
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Coordinate nontrivial work in the ctx repository when a task has independent investigation, implementation, or test lanes; compute-heavy checks; or repetitive changes suited to scripts or codemods. Use for decomposition and concurrency decisions, not simple edits or questions.
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Suggest meals and cooking plans from supplied ingredients and preferences. Use for this Bot Generator Bot template; creates drafts or simulations within its declared scope.
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