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Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.

日本語の概要は準備中です。原文の説明を表示しています。

Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.

日本語の概要は準備中です。原文の説明を表示しています。

Query protein-protein and gene interaction databases (STRING, BioGRID, IntAct, SIGNOR, Reactome, HuRI, HuMAP, OmniPath, ConsensusPathDB, DIP). Use when building PPI networks, choosing between physical vs functional vs genetic interactions, signed/directed vs undirected, high-throughput vs curated, picking confidence thresholds, aggregating across resources, or navigating license constraints. Encodes the database decision matrix, STRING v12 channel semantics, OmniPath as meta-database, SIGNOR for signed signaling, and per-resource rate limits.

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Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.

日本語の概要は準備中です。原文の説明を表示しています。

Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

日本語の概要は準備中です。原文の説明を表示しています。

Queries PharmGKB / CPIC / DPWG for drug-gene interactions; calls CYP2D6/CYP2C9/CYP2C19/DPYD/TPMT/NUDT15/UGT1A1/SLCO1B1 star alleles and phenotype with PharmCAT, Cyrius (CYP2D6 structural variants), Aldy, Stargazer; applies Caudle 2020 activity-score translation. Use when implementing pharmacogenomic-guided prescribing, applying CPIC vs DPWG guidance, screening HLA risk alleles for ICI / antiepileptics / abacavir, or interpreting compound TPMT+NUDT15 thiopurine risk.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building ANY 2D or 3D game with SpriteKit, SceneKit, or RealityKit, or adding touch controls or game controller support. Covers scene graphs, ECS, physics, actions, game loops, rendering, TouchController, GCController.

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Implement, review, or improve in-app purchases and subscriptions using StoreKit 2. Use when building paywalls with SubscriptionStoreView or ProductView, processing transactions with Product and Transaction APIs, verifying entitlements, handling purchase flows (consumable, non-consumable, auto-renewable), implementing offer codes or promotional/win-back/introductory offers, managing subscription status and renewal state, setting up StoreKit testing with configuration files, or integrating Family Sharing, Ask to Buy, refund handling, and billing retry logic.

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Build SwiftUI layouts using stacks, grids, lists, scroll views, forms, and controls. Covers VStack/HStack/ZStack, LazyVGrid/LazyHGrid, List with sections and swipe actions, ScrollView with ScrollPosition and scroll-driven reveal surfaces, Form with validation, Toggle/Picker/Slider, .searchable, and overlay patterns. Use when building data-driven layouts, collection views, paged detail reveals, settings screens, search interfaces, or transient overlay UI.

日本語の概要は準備中です。原文の説明を表示しています。

Build iOS augmented reality and 3D experiences with RealityKit and ARKit. Use when adding RealityView content, loading entities or USDZ models, anchoring objects to planes or world positions, distinguishing entity hit tests from ARKit real-world raycasts, handling AR camera availability, world tracking, scene updates, or RealityKit entity gestures and interactions.

日本語の概要は準備中です。原文の説明を表示しています。

Implement and review Apple TipKit feature-discovery UI for iOS 17+ apps. Use when adding or auditing in-app tips, contextual help, coach marks, Tip, TipView, popoverTip, rules, events, actions, display frequency, testing overrides, reusable tip identifiers, or iOS 18+ TipGroup and CloudKit tip sync; avoid for generic SwiftUI navigation or layout outside tip presentation.

日本語の概要は準備中です。原文の説明を表示しています。

Implements keyboard, directional, and scene-level focus behavior across SwiftUI and UIKit. Use when managing @FocusState, defaultFocus, focused values, focusable interactions, focus sections, tvOS geometric focus and Siri Remote navigation, watchOS Digital Crown input, visionOS connected-device focus versus gaze hover/input targets, macOS key view loop and Full Keyboard Access, focus restoration after presentation changes, custom focus routing with UIFocusGuide, or debugging focus with UIFocusDebugger.

日本語の概要は準備中です。原文の説明を表示しています。

Access eligible Wallet financial data using FinanceKit and FinanceKitUI. Use when querying transactions or balances, reading Apple Card, Apple Cash, Savings, or U.K. connected-account data, requesting financial-data authorization, using TransactionPicker, enabling iOS 26 background delivery, or saving and checking Wallet orders.

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Implement AlarmKit alarms and countdown timers for iOS and iPadOS with Lock Screen, Dynamic Island, StandBy, and paired Apple Watch system UI. Covers AlarmManager scheduling, AlarmAttributes and AlarmPresentation, system Stop and AlarmButton secondary actions, authorization, state observation, countdown widget-extension handoff, and Live Activity integration. Use when building wake-up alarms, countdown timers, or alarm-style alerts that need Apple's system alarm experience.

日本語の概要は準備中です。原文の説明を表示しています。

Access Core Motion accelerometer, gyroscope, magnetometer, device-motion, pedometer, activity-recognition, altitude, headphone motion, batched high-frequency workout motion, and water-submersion/depth data. Use when reading device sensors, counting steps, detecting walking/running/driving/cycling, tracking altitude, building motion interactions, handling AirPods head tracking, or implementing watchOS dive/depth features.

日本語の概要は準備中です。原文の説明を表示しています。

Implement VoIP calling with CallKit and PushKit. Use when building incoming/outgoing call flows, registering for VoIP push notifications, configuring CXProvider and CXCallController, handling call actions, coordinating audio sessions, or creating Call Directory extensions for caller ID and call blocking.

日本語の概要は準備中です。原文の説明を表示しています。

Build and audit SwiftUI, UIKit, and AppKit accessibility for VoiceOver, Voice Control, Switch Control, Full Keyboard Access, Dynamic Type, focus restoration, labels/traits/actions, traversal, custom rotors, NSAccessibility, XCTest checks, adaptive system preferences, and App Store accessibility declarations. Use when implementing accessible UI, fixing an accessibility audit, testing assistive-technology behavior, or substantiating App Store Accessibility Nutrition Labels.

日本語の概要は準備中です。原文の説明を表示しています。

使用 GitHub CLI (`gh`) 执行非交互式 GitHub 协作与自动化任务（PR、Issue、Actions、Release、API 查询/修改）。当用户要求“用 gh 命令完成任务”、需要结构化 JSON 输出（`--json`/`--jq`）、批量处理 PR/Issue（如“批量 review 多个 PR”）、按策略合并（如“检查通过后自动 squash 合并”）时使用此 skill。

日本語の概要は準備中です。原文の説明を表示しています。

Set up and run wireless network simulations using the Wireless Network Toolbox. Use this skill when creating system-level simulations with wirelessNetworkSimulator, adding traffic sources (networkTrafficOnOff, networkTrafficFTP, networkTrafficVoIP, networkTrafficVideoConference), configuring node mobility, logging events or IQ samples, visualizing traffic, scheduling actions during simulation, running parametric sweeps, writing PCAP files with pcapWriter or technology-specific PCAP writers, registering event callbacks on wireless nodes, accessing event data fields, or combining multiple capture/visualization tools in a simulation.

日本語の概要は準備中です。原文の説明を表示しています。

Reads from, writes to, and manages relational databases using MATLAB Database Toolbox. Use when connecting to databases, reading data with sqlread or fetch, filtering with rowfilter, writing with sqlwrite, updating with sqlupdate, executing SQL statements, managing transactions with commit and rollback, mapping MATLAB classes to tables with ORM (Mappable, ormread, ormwrite, ormupdate), or performing any database operation from MATLAB. Triggers on: database, SQL, sqlread, sqlwrite, sqlupdate, fetch, execute, rowfilter, RowFilter, ORM, Mappable, ormread, ormwrite, ormupdate, orm2sql, transaction, commit, rollback, Database Toolbox, PostgreSQL, MySQL, SQLite, SQL Server, Oracle, database connection, database table, query database, insert data, update rows, delete rows, stored procedure, prepared statement, odbc, databaseConnectionOptions, datasource, data source, DSN, connection string, multithreaded, parallel.

日本語の概要は準備中です。原文の説明を表示しています。

Programmatically author RoadRunner scenarios from MATLAB using roadrunnerAPI. Use when adding actors, creating routes, building scenario logic (phases, conditions, actions), placing vehicles/pedestrians, defining cut-in/crossing/ follow scenarios, or any programmatic scenario creation in RoadRunner. Triggers on: roadrunnerAPI, scenario authoring, add actor, create route, phase logic, cut-in scenario, pedestrian crossing, scenario from MATLAB.

日本語の概要は準備中です。原文の説明を表示しています。

Reusable git delivery workflows derived from local slash commands (commit, push, PR, release notes, GitHub Actions failure triage with worktree-based fixes, and isolating your own changes from a shared dirty workspace).

日本語の概要は準備中です。原文の説明を表示しています。

Use when driving a desktop GUI through a computer-use driver — windows, menus, native apps, OS dialogs. You build a table of safe actions; Jev picks the next one in about 0.4 seconds.

日本語の概要は準備中です。原文の説明を表示しています。

Use when researching social posts, creators, reactions, or trends. Jev ranks discovery cards and decides when opened, source-linked evidence is enough for a bounded report.

日本語の概要は準備中です。原文の説明を表示しています。