「2025」の検索結果

Analyzes CUT&RUN (Skene Henikoff 2017) and CUT&Tag (Kaya-Okur 2019) chromatin profiling data. Handles SEACR vs MACS2 peak calling (with the btaf375 2025 benchmark guidance), pA-MNase vs pA-Tn5 vs pAG-Tn5 chimera differences, E. coli spike-in carryover normalization, IgG-only control logic (no input), characteristic fragment-size signatures (25-75 bp for CUT&Tag), and lower depth requirements (5M reads typical vs 25M for ChIP). Use when calling peaks from CUT&RUN/CUT&Tag, scaling by E. coli spike-in carryover, choosing SEACR norm mode, or comparing CUT&RUN/Tag results to traditional ChIP.

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Detects differential alternative splicing between conditions using rMATS-turbo (binomial LRT on junction counts), leafcutter (Dirichlet-multinomial GLM on intron clusters), MAJIQ V3 deltapsi/HET (Bayesian posterior on LSVs), SUPPA2 (empirical-null on TPM-derived PSI), or Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage). Reports FDR-corrected significance and delta PSI effect sizes. Tools differ in statistical model, annotation dependence, calibration regime, and replicate-count requirements. Use when comparing splicing patterns between treatment groups, tissues, or disease states.

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Quantifies alternative splicing as PSI (percent spliced in) from RNA-seq using rMATS-turbo (BAM-based event), SUPPA2 (TPM-based event), MAJIQ V3 (LSV-based Bayesian), leafcutter (annotation-free intron clusters), VAST-TOOLS (cross-species with microexon support), Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage), or IRFinder-S (intron retention coverage-aware). Distinguishes the five canonical event classes (SE, A5SS, A3SS, MXE, RI), special classes (microexons, exitrons, AFE/ALE), intron retention subtypes (canonical RI vs detained introns), and applies effective-length normalization. Use when measuring splice-site usage or isoform inclusion ratios from short-read RNA-seq.

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Reference for MATLAB audiostreamer (Audio Toolbox R2025a+). Without this skill, agents consistently default to legacy audioDeviceWriter/audioDeviceReader or base MATLAB sound(), producing less capable code. Use when writing code for audio playback, recording, full-duplex device I/O, real-time audio measurements, or audio I/O processing with callbacks. Also use when debugging audiostreamer errors, dropouts, or latency issues, or migrating from audioDeviceReader, audioDeviceWriter, audioPlayerRecorder, or audioplayer/audiorecorder.

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Style MATLAB charts and figures. colororder palettes for chart series colors, colormap selection, brand color organization, and the R2025a Theme API for uifigure apps (dark mode with fliplightness, ThemeChangedFcn, uistyle, component colors). Use when customizing chart colors, applying a color palette, organizing brand colors, implementing dark mode, or importing an external color scheme. Triggers: theme, dark mode, brand colors, colororder, colormap, palette, fliplightness, color scheme, styling, chart colors.

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Create, edit, and run plain-text MATLAB live scripts (.m files) with rich text formatting, LaTeX equations, section breaks, and inline figures. Use when generating tutorials, analysis notebooks, reports, documentation, or educational content, when modifying existing live scripts, or when converting existing binary .mlx files to .m for version control. Requires R2025a+.

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Modern web design trends, principles, and implementation patterns for 2024-2025. Use this skill when designing websites, creating interactive experiences, implementing design systems, ensuring accessibility, or building performance-first interfaces. Triggers on tasks involving modern design trends, micro-interactions, scrollytelling, bold minimalism, cursor UX, glassmorphism, accessibility compliance, performance optimization, or design system architecture. References animation skills (GSAP, Framer Motion, React Spring), 3D skills (Three.js, R3F, Babylon.js), and component libraries for implementation guidance.

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Use when doing any Autodesk Maya task through Python or a bridge, headless or live: maya.cmds or OpenMaya 2.0 scripts, mayapy or maya.standalone batch jobs, a commandPort or MCP connection into a running Maya, "Maya 2027", validating or exporting scenes, or a maya.cmds script that fails after the 2025 to 2027 changes (PySide6, OpenPBR, renamed math nodes, removed flags). Also when a Maya model, rig, shot or render must be judged like a professional before it is called done, or a brief must be routed to the right Maya specialist.

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United Arab Emirates Governance, Risk & Compliance advisor — a jurisdiction-first compliance router. In the UAE, WHERE an organization sits determines its law: mainland (Federal PDPL, Decree-Law 45/2021 — executive regulations still pending), DIFC (DP Law No. 5 of 2020 as amended 2025, with a private right of action), ADGM (DP Regulations 2021), CBUAE-licensed financial institutions (consumer-data residency, outsourcing approvals), healthcare (ICT Health Law data localization), and government/CNI (UAE IA Regulation, Cyber Security Council; Dubai ISR, ADHICS). Use for any UAE / Dubai / Abu Dhabi / Emirates compliance question: UAE data protection, DIFC or ADGM privacy, free-zone vs mainland obligations, health-data residency, CBUAE cyber and outsourcing rules, market entry ("expanding to the UAE"), breach notification, gap assessments, and mapping UAE requirements to ISO 27001 / NIST CSF / SOC 2. Trigger for any UAE privacy, cybersecurity, or regulatory question even if no framework is named.

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Expert India Digital Personal Data Protection Act, 2023 (DPDPA) compliance advisor. Use this skill whenever a user asks about the DPDPA, DPDP Act, DPDP Rules 2025, India data privacy law, Data Fiduciary obligations, Data Principal rights, Significant Data Fiduciary, Data Protection Board of India, consent under DPDPA, notice requirements, breach notification India, children's data India, cross-border data transfer India, India privacy compliance, DPDPA gap analysis, DPDPA vs GDPR, or any obligation under India's personal data protection framework. Also trigger for: "Section 6 consent", "Section 7 legitimate uses", "Section 9 children's data", "Section 10 SDF", "Section 16 cross-border", "Rule 6 breach notification", "Rule 13 SDF obligations", "Data Protection Board complaint", "verifiable parental consent India", "DPDPA compliance roadmap", or "India privacy law global company".

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Expert ISO 27701 Privacy Information Management System (PIMS) compliance advisor. Use this skill whenever a user asks about ISO/IEC 27701:2025, ISO/IEC 27701:2019, privacy information management, PIMS certification, PII controller or processor obligations, privacy risk assessment, Statement of Applicability for privacy, privacy by design, data subject rights, DPIA, records of processing activities, transitioning from ISO 27701:2019, GDPR alignment with ISO 27701, or any privacy management system topic. Also trigger for questions about Annex A.1 (controller controls), A.2 (processor controls), A.3 (shared security controls), or implementing a standalone PIMS without ISO 27001. When in doubt, use this skill — it covers the full ISO 27701 lifecycle from gap assessment through certification.

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EU AI Act (Regulation (EU) 2024/1689) compliance advisor — risk classification across all four tiers, all 9 prohibited practices (Art. 5, including the nudification/CSAM prohibition from Dec 2, 2026), all 8 Annex III high-risk use case areas, provider and deployer obligations (Arts. 9–17, 26), GPAI model obligations including the July 2025 Code of Practice (Arts. 51–55), conformity assessment and CE marking (Arts. 43–48), EU AI database registration, Art. 50 transparency (chatbots, synthetic media, AI-generated content), governance (AI Office, AI Board), penalties (Art. 99), confirmed phase-in timeline (Digital Omnibus, Reg. (EU) 2026/1744, in force July 27, 2026: Annex III deferred to Dec 2, 2027; Annex I to Aug 2, 2028), and cross-framework mapping to ISO 42001, NIST AI RMF, and GDPR. Use for any EU AI regulation, AI system classification, or AI compliance question. Current as of August 2026. GPAI enforcement powers active since August 2, 2026.

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Real-time web search using Playwright-controlled browser. Use this skill when you need current information, latest documentation, recent news, or any data beyond your knowledge cutoff (January 2025).

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宝玉xp（前微软MVP/2025微博年度新知博主/AI提示词方法论专家）的AI科普与内容创作思维——工程师思维+提示词系统教学+开源共享+日更坚持。 触发词：「宝玉视角」「像宝玉那样写」「宝玉xp」「提示词教程」「AI工具推荐」「baoyu-skills」「提示词方法论」。 擅长：AI提示词系统化教学（Level 1-10）、技术翻译+个人解读、AI工具实测推荐、开源项目运营（baoyu-skills）、日更知识库维护（宝玉日报）、技术大会演讲。

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File Indian income tax returns for FY 2025-26 (AY 2026-27), or plan FY 2026-27 (Tax Year 2026-27), including current-year advance-tax estimates. Use when the user wants to file their ITR, compute or verify Indian income tax, compare the old vs new tax regime, read a Form 16, AIS, TIS or Form 26AS, reconcile TDS, handle capital gains from Zerodha/Groww/Upstox statements, check their tax refund, or asks about ITR-1/ITR-2/ITR-3/ITR-4, sections 80C/80D/87A/111A/112A, crypto tax, advance tax, or the income-tax e-filing portal - even if they just say "help me with my taxes" in an Indian context.

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GDPR Transfer Impact Assessment for Chapter V transfers under the EDPB Recommendations 01/2020 six-step methodology, the CNIL TIA Guide (January 2025), and EDPB essential guarantees. Handles transfer qualification, Art. 45 adequacy fast-tracks, Art. 46 full assessments with country profiles for 12 jurisdictions, and balanced Art. 49 derogation analysis. Outputs a Markdown report, a .docx formal TIA, and a JSON delta for RoPA interchange.

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GDPR Legitimate Interest Assessment (LIA) — Guided assessment for Art. 6(1)(f) GDPR using the EDPB three-step test. Based on EDPB Guidelines 1/2024, EDPB Opinion 28/2024 (AI models), the OSS Case Digest on Legitimate Interest (McIntyre 2026), CNIL AI guidance (June 2025), ICO guidance, and key CJEU case law. Use when: (1) user needs to assess whether legitimate interest is appropriate, (2) user asks about Art. 6(1)(f), "Interessenabwägung", "berechtigtes Interesse", "balancing test", or "LIA", (3) user wants to document a legitimate interest assessment, (4) user mentions the three-step test, (5) user evaluates necessity or proportionality under Art. 6(1)(f), (6) user discusses direct marketing, fraud prevention, IT security, employee monitoring, AI training, web scraping, or credit checks in context of legal basis, (7) user handles a right to object (Art. 21), (8) user asks about children's data, profiling, or cross-border data sharing under legitimate interest, (9) user compares legitimate interest against other legal bases. Do NOT use for: consent assessments (Art. 6(1)(a)), contract performance (Art. 6(1)(b)), DPIA workflows, or pure ePrivacy/cookie compliance questions — though the skill does address the ePrivacy/GDPR overlap where relevant.

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Draft or review a DPDPA-compliant consent notice under India's Digital Personal Data Protection Act, 2023 and DPDPA Rules, 2025. Provide basic details about your business and this skill handles the rest - building a notice tailored to your operations, with all required sections, granular consent boxes, and internal notes for your team. If you have an existing notice or privacy policy that needs to comply with DPDPA, this skill revises it too, flagging key gaps and changes made.

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Expert ISO 27701 Privacy Information Management System (PIMS) compliance advisor. Use this skill whenever a user asks about ISO/IEC 27701:2025, ISO/IEC 27701:2019, privacy information management, PIMS certification, PII controller or processor obligations, privacy risk assessment, Statement of Applicability for privacy, privacy by design, data subject rights, DPIA, records of processing activities, transitioning from ISO 27701:2019, GDPR alignment with ISO 27701, or any privacy management system topic. Also trigger for questions about Annex A.1 (controller controls), A.2 (processor controls), A.3 (shared security controls), or implementing a standalone PIMS without ISO 27001. When in doubt, use this skill — it covers the full ISO 27701 lifecycle from gap assessment through certification.

日本語の概要は準備中です。原文の説明を表示しています。

Expert India Digital Personal Data Protection Act, 2023 (DPDPA) compliance advisor. Use this skill whenever a user asks about the DPDPA, DPDP Act, DPDP Rules 2025, India data privacy law, Data Fiduciary obligations, Data Principal rights, Significant Data Fiduciary, Data Protection Board of India, consent under DPDPA, notice requirements, breach notification India, children's data India, cross-border data transfer India, India privacy compliance, DPDPA gap analysis, DPDPA vs GDPR, or any obligation under India's personal data protection framework. Also trigger for: "Section 6 consent", "Section 7 legitimate uses", "Section 9 children's data", "Section 10 SDF", "Section 16 cross-border", "Rule 6 breach notification", "Rule 13 SDF obligations", "Data Protection Board complaint", "verifiable parental consent India", "DPDPA compliance roadmap", or "India privacy law global company".

日本語の概要は準備中です。原文の説明を表示しています。

EU AI Act (Regulation (EU) 2024/1689) compliance advisor — risk classification across all four tiers, all 9 prohibited practices (Art. 5, including the nudification/CSAM prohibition from Dec 2, 2026), all 8 Annex III high-risk use case areas, provider and deployer obligations (Arts. 9–17, 26), GPAI model obligations including the July 2025 Code of Practice (Arts. 51–55), conformity assessment and CE marking (Arts. 43–48), EU AI database registration, Art. 50 transparency (chatbots, synthetic media, AI-generated content), governance (AI Office, AI Board), penalties (Art. 99), confirmed phase-in timeline (Digital Omnibus adopted June 29, 2026: Annex III deferred to Dec 2, 2027; Annex I to Aug 2, 2028), and cross-framework mapping to ISO 42001, NIST AI RMF, and GDPR. Use for any EU AI regulation, AI system classification, or AI compliance question. Current as of July 2026. GPAI enforcement powers activate August 2, 2026.

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Index analytiques sourcés du corpus réglementaire et doctrinal sur la gouvernance des émetteurs cotés français (rapports AMF et HCGE 2020-2025, guide d'application HCGE, rapport sénatorial Rietmann/Gay, Code AFEP-MEDEF, sources légales et européennes). À utiliser pour : (1) retrouver une position, une statistique ou une citation exacte avec sa source et sa page ; (2) analyser l'évolution longitudinale des positions AMF/HCGE/ESMA sur un thème ; (3) appliquer la grille d'analyse en 13 blocs (A-M) à un émetteur. Déclencher pour toute question sur la gouvernance d'une société cotée française : conseil d'administration, indépendance des administrateurs, comités, rémunération des dirigeants, say on pay, say on climate, assemblée générale, droits des actionnaires, plans de succession, mixité, RSE/CSRD, comply-or-explain, name and shame AMF, soft law AFEP-MEDEF, recommandations AMF, positions HCGE.

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Dung khi da co MOT master design va can ra du kich thuoc cho tat ca kenh — bang kich thuoc chuan 2025-2026 cho feed, story, reel, cover, placement ads; 3 cach xu ly scale-crop, re-compose, rebuild; quy tac safe zone va cach dat ten file. Kich hoat khi user nhac 'resize asset', 'du kich thuoc', 'adapt kich thuoc', 'bang kich thuoc chuan', 'safe zone', 'anh bi cat mat chu tren story', 'mot anh dang duoc may cho'. Khong dung cho — thiet ke moi tu concept thi dung skill 42-brief-hinh-anh; asset gap khi campaign dang chay thi dung skill 48-quick-visual-brief; liet ke toan bo asset cua campaign thi dung skill 41-campaign-asset-list.

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한국 서비스용 처리방침·이용약관·회원가입 동의 모달·쿠키 배너 자동 생성. 개인정보보호법 §30, 2025.4.21 작성지침, 2026.3 개정법, 공정위 전자상거래 표준약관 10023호 반영. Next.js 13~16 프로젝트 대상.

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