「agm」の検索結果

Remove AI tells from LinkedIn posts/comments: 2026 vocabulary density, reveal bridges, staccato fragments, stacked triads, performed sincerity. Tiered rewriter plus `--mode audit` LinkedIn post auditor and `--mode profile` voice builder. Not for drafting from scratch (use linkedin-post-writer) or beating AI detectors. Keywords: humanize, de-AI, post audit, post auditor, audit before posting.

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Evaluates your campaign and ad set structure against your actual goals and budget. Flags over-segmentation that fragments your data, under-segmentation that hides performance differences, budget allocation issues, and consolidation opportunities that would improve algorithmic delivery and your ability to optimize. Platform: Google and Meta.

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High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.

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ChIP-seq peak calling using MACS3 (or MACS2). Call narrow peaks for transcription factors or broad peaks for histone modifications. Supports input control, fragment size modeling, and various output formats including narrowPeak and broadPeak BED files. Use when calling peaks from ChIP-seq alignments.

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Quality control metrics for ATAC-seq data including fragment size distribution, TSS enrichment, FRiP, and library complexity. Use when assessing ATAC-seq library quality before or after peak calling to identify problematic samples.

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TypeScript code shape inside a well-named module — taste, not lint. Prefer one class or namespace per file (the unit a test targets) over scattered free exports; consolidate related code, don't fragment. The unit of code should be the unit of spec. Use when authoring TS in `editor/grida-canvas*`, `editor/lib/`, or `packages/*`. Sibling to the `naming` skill; React-specific shape lives in `code-react`.

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Role profile — a reviewer who is fact-seeking, bedrock-seeking, honest, and rejecting. Demands that arguments rest on small facts that cannot be wrong (not on stacked assumptions dressed up as foundation), and that deliberately-unclear concepts be quarantined — never leaked into solid layers, never mixed with each other. Catches the failure mode where designs ship after partial grounding: most of the spec researched, the design feels finished, and the unresearched remainder holds the deal-breaker. Invoke with `/pedantic <target>` (e.g. `/pedantic review this design doc`, `/pedantic review the SDK design`, `/pedantic review this PR`). Probes cover logical structure (definitions, assumptions, boundaries, contradictions, unfalsifiability, vague quantifiers, counterexamples), epistemic honesty (researchable vs. discoverable-only-by-doing), bedrock integrity (assumed-bedrock, leaked uncertainty, mixed unclarity), and design pathology (YAGNI, wrong-layer abstraction, unclear responsibility, fragmentation, over-engineering). Use when you want a hard critique of a plan, design doc, technical doc, code change, or PR description — not a copy edit, not a vibe check.

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Guided journey from a large aged codebase everyone fears to touch to one that is safe to change, legible, bounded, and resilient - paid down in place without a rewrite. Orchestrates eight skills phase by phase - working-with-legacy-code, refactoring-patterns, clean-code, software-design-philosophy, clean-architecture, pragmatic-programmer, release-it, domain-driven-design - asking the user questions at every decision point and recording results in the project docs/ folder (TESTING.md, TECH-DEBT.md, REMOVE-TECHNICAL-DEBT-PLAN.md) so the journey resumes across sessions. Use when the user wants to tame a legacy codebase, pay down technical debt safely, avoid a big-bang rewrite, or says 'we are afraid to touch this code'. For a fresh vibe-coded prototype, improve-code-quality; for greenfield structure, design-code-architecture; for a product-and-UX pass, improve-app; to optimize a working codebase for speed, architecture-optimization. For one framework in isolation, invoke that skill directly.

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Navigate the technology adoption lifecycle from early adopters to mainstream market. Use when the user mentions "crossing the chasm", "beachhead segment", "whole product", "early adopters vs mainstream", "tech go-to-market", "bowling pin strategy", "technology adoption lifecycle", "pragmatist buyers", "growth stalled after early adopters", or "our go-to-market plan". Also trigger when planning go-to-market for a technical product. Covers the D-Day analogy, bowling-pin strategy, the tornado, and positioning against incumbents. For product positioning, see obviously-awesome. For new market creation, see blue-ocean-strategy.

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Guided journey from a raw app idea to a validated, cleanly architected first version that ships on a sustainable cadence. Orchestrates ten skills phase by phase - lean-startup, design-sprint, clean-architecture, domain-driven-design, clean-code, pragmatic-programmer, system-design, ios-hig-design, 37signals-way, software-design-philosophy - asking the user questions at every decision point and recording results in the project docs/ folder (PRODUCT.md, ARCHITECTURE.md, EXPERIMENTS.md, CREATE-APP-PLAN.md) so the journey resumes across sessions. Use when the user wants to build a new app, validate an idea before writing code, architect an MVP that will not need a rewrite, or says 'help me build my app the right way'. App already exists: use improve-app or grow-app. Business idea not yet validated: run create-business first. Marketing site only: use create-website. Architecture-only question: design-code-architecture. For one framework in isolation, invoke that skill directly.

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Guided journey from a working-but-untested vibe-coded prototype to a production-ready product with tests, clean structure, a business-rules boundary, and resilience at scale. Orchestrates nine skills phase by phase - working-with-legacy-code, clean-code, refactoring-patterns, software-design-philosophy, clean-architecture, pragmatic-programmer, release-it, system-design, ddia-systems - asking the user questions at every decision point and recording results in the project docs/ folder (TESTING.md, TECH-DEBT.md, IMPROVE-CODE-QUALITY-PLAN.md) so the journey resumes across sessions. Use when the user wants to harden an AI-generated prototype, add tests before refactoring, make code safe to change, or says 'this works on my machine but I am scared to touch it'. For an aged codebase, remove-technical-debt; for greenfield structure, design-code-architecture; for a product and UX pass, improve-app; to optimize speed and structure, architecture-optimization. For one framework in isolation, invoke that skill directly.

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Guided journey from an app idea to a deliberate architecture: boundaries, domain model, data decisions, and resilience, making only the expensive-to-reverse decisions and deferring the rest. Orchestrates eight skills phase by phase - clean-architecture, domain-driven-design, system-design, ddia-systems, software-design-philosophy, release-it, pragmatic-programmer, 37signals-way - asking the user questions at every decision point and recording results in the project docs/ folder (ARCHITECTURE.md, DESIGN-CODE-ARCHITECTURE-PLAN.md) so the journey resumes across sessions. Use when the user wants to design a new app's architecture, choose boundaries and a domain model, decide monolith versus microservices, or says 'how should I structure this app'. If a codebase already exists, use remove-technical-debt (aged), improve-code-quality (fresh prototype), or architecture-optimization (slow but working); if unvalidated, run create-business or create-app first. For one framework in isolation, invoke that skill directly.

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Guided journey from a working codebase grown slow and tangled to one measurably fast, cleanly bounded, and readable. Orchestrates eight skills phase by phase - working-with-legacy-code, clean-architecture, software-design-philosophy, refactoring-patterns, system-design, ddia-systems, release-it, pragmatic-programmer - every phase carries its method inline so it runs standalone, asking the user questions at every decision point and recording results in the project docs/ folder (PERFORMANCE.md, ARCHITECTURE.md, ARCHITECTURE-OPTIMIZATION-PLAN.md) so the journey resumes across sessions. Use when the user wants to make an app faster, untangle drifted boundaries, fix slow endpoints and queries, or says 'it works but it is slow and getting worse'. For an untested prototype, improve-code-quality; for an aged codebase you fear to touch, remove-technical-debt; for greenfield structure, design-code-architecture; for marketing-site page speed, improve-website. For one framework in isolation, invoke that skill directly.

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Debug and emulate specific code fragments or functions using the Unicorn engine. Activate when the user wants to emulate a function with Unicorn, trace binary execution without running the full program, decrypt or decode data by emulating the algorithm, or bypass environment dependencies (JNI, syscalls, libc) during emulation.

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A high-performance Rust toolkit (with Python bindings and a CLI) for genomic interval analysis; use it when you need fast overlap queries, coverage track generation, genomic tokenization for ML, reference sequence verification, or fragment processing.

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Choose placements that preserve useful residual capacity. Use for bin packing, GPU sharing, accelerator placement, and multi-resource scheduling where stranded capacity hurts future fit.

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Govern how the design system evolves — SemVer for tokens/components, the contribution workflow, deprecation policy, and change communication. Use when the user wants to add/promote/deprecate a component or token, decide a version bump, set up a contribution process, or keep the system from fragmenting.

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Mainland-Chinese TV-series craft, documents and production chain (国产剧创作体系与制片链) — the China layer parallel to the Japanese and Korean/French skills. Distilled from Yao Kougen 姚扣根《电视剧写作概论》(2016; series taxonomy, four Chinese script formats, the 3-minute/15-minute/episode-end suspense law, 36 situations), Zhang Wei 张巍《电视剧改编教程》(2014; five source types, sell-point migration, six case studies), Zhang Mingzhi & Song Peiyi《电视剧出品人与制片人教程》(2016; running-time rules, two-stage censorship, scene-breakdown sheet, contracts), Zhao Binbin《影视剧片段改编教程》(2016; film to stage fragment), plus official Chinese renderings of US TV terms from the translated Douglas and Blum textbooks. Use when writing or judging a 国产剧, turning a novel or IP into a 30–50 episode drama, writing a 策划书 / 分集梗概 / 人物小传, formatting a Chinese teleplay, sizing episode count and word count, checking content red lines and the 立项/备案/审查 chain, reading a Chinese screenwriter contract, or mapping US series vocabulary onto Chinese usage.

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Use only after explicit Codex `$superloopy:i-have-adhd` or Claude Code `/superloopy:i-have-adhd` invocation, or when a qualifying leading `loopy`/`루피` task receives Superloopy's non-diagnostic ADHD-friendly output overlay. Do not activate from typos, fragmented writing, urgency, grammar, language proficiency, or ordinary discussion of ADHD, attention, focus, accessibility, or cognitive load.

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Use when judging whether a management/organization literature is an Academy of Management Annals (Annals)-scale review topic — mature, important, fragmented, and integrable into a new framework — rather than a narrow review. Decides fit and frames the review's animating problem; it does not gather the literature (amann-literature-synthesis) or write the proposal (amann-proposal-framing).

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Detects cancer and infers tissue-of-origin from cfDNA methylation by choosing conversion chemistry (bisulfite vs EM-seq vs TAPS vs cfMeDIP), calling read-level methylation haplotypes rather than averaged beta values, and deconvolving a hematopoietic-dominated cfDNA mixture against a methylation atlas via NNLS/quadratic programming. Encodes the GRAIL/CCGA thesis that thousands of tissue-specific markers make methylation outperform sparse mutations for multi-cancer early detection (MCED) and localization, and that single concordantly-methylated fragments give ppm-level sensitivity. Uses MethylDackel for extraction (mbias-then-extract), MEDIPS/QSEA for enrichment data, scipy.optimize.nnls for deconvolution. Use when building an MCED or methylation-MRD assay, picking a conversion chemistry for low-input plasma, or deconvolving tissue-of-origin from cfDNA.

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Estimates tumor fraction (the genome-wide proportion of cfDNA molecules that are tumor-derived, the cfDNA analogue of bulk-tumor purity) from shallow whole-genome sequencing with ichorCNA, an HMM over 1 Mb bins that jointly EM-estimates tumor fraction, ploidy, and subclonal prevalence over a normal/ploidy grid. Encodes the load-bearing reframes: tumor fraction is the quantity that travels across assays and is NOT mutation VAF (clonal-het VAF approximately TF/2), CNA-based estimation has a hard ~3 percent limit-of-detection floor, and near-diploid or copy-neutral-LOH genomes return a falsely low value. Selects the estimator by data type (sWGS to ichorCNA, deep panel to max-VAF, methylation to deconvolution, sub-3 percent to fragmentomics or methylation). Use when quantifying tumor burden from a liquid biopsy, picking a tumor-fraction estimator for a given assay, or reconciling a TF estimate against a panel VAF.

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Computes and interprets sequencing read depth and coverage over a genome, windows, or target regions with mosdepth (windowed depth, cumulative distribution, --quantize callable BEDs), bedtools genomecov/coverage (bedGraph tracks, per-target stats), samtools depth/coverage (per-base depth, per-contig depth+breadth). Covers the breadth-vs-mean distinction, the cumulative-coverage curve, evenness (CV/Fano/fold-80/Gini), what each tool silently counts (duplicates, secondary/supplementary, MAPQ, read span vs fragment, mate-overlap), the samtools-depth 8000-cap version trap, and the bedtools coverage -a/-b orientation flip. Use when assessing sequencing adequacy, building coverage tracks, computing breadth at a depth threshold, defining callable regions, or QCing target-capture uniformity.

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Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why N50 is the most-gamed metric, why QV measured on the polishing reads is circular, distinguishing uncollapsed haplotigs from real WGD, and the EBP/VGP 6.C.Q40 standard. Use when judging whether an assembly is good enough to annotate or publish, comparing assemblers, diagnosing a fragmented or duplicated assembly, or assessing a phased diploid assembly.

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