309 件 ・ 関連度順
概要と使いどころ
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
日本語の概要は準備中です。原文の説明を表示しています。
書きたいテーマを質問で掘り下げ、印象的な一文や体験、比喩、考えかけの断片を集めます。構成は決めず、文章の素材を一つのMarkdownファイルに蓄積します。
Analyze restriction digest fragments using Biopython Bio.Restriction. Predict fragment sizes, get fragment sequences, simulate gel electrophoresis patterns, and perform double digests. Use when analyzing restriction digest fragment patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Extracts cfDNA fragmentomics features (DELFI genome-wide short/long ratios, WPS nucleosome positioning, Griffin GC-corrected accessibility profiles, end-motifs/MDS, OCF) for cancer detection and tissue-of-origin from plasma WGS. Centers on the nuclease-footprint reframe (every feature re-reads one nucleosome object), the mandatory GC correction, and the cross-protocol non-comparability that breaks naive classifiers. Runs FinaleToolkit (real CLI/Python, MIT) and the Griffin Snakemake pipeline; DELFI is a method, not a package. Use when deriving fragment-based signal from cfDNA, choosing a feature family for detection vs subtyping, or diagnosing why a fragmentomic model failed validation.
日本語の概要は準備中です。原文の説明を表示しています。
Give your OpenClaw agent a homelab. Use when managing Docker containers, installing marketplace apps, or any Docker-related tasks on behalf of the user. Scope-based API key permissions — agent can only do what the key allows. On Linux, Docker requires sudo — without root access, WAGMIOS is the only safe interface for agent homelab control. Supports multi-machine management — one agent can manage multiple WAGMIOS instances across different hosts, each with its own scoped key. Requires X-API-Key header on every request (user provides at runtime). Includes Docker installation check and startup validation.
日本語の概要は準備中です。原文の説明を表示しています。
Assemble a finished piece from human-written fragments via an orchestrated two-loop pipeline - an assembly loop (assembler + cold reviewer) that sequences the fragments into a draft, then a polish loop (polisher + cold reviewer), then frequency analysis and a catalog-deslop pass with a regression gate. Two modes with opposite fidelity contracts - stitch mode preserves the author's exact wording, narrative mode preserves every idea but may rewrite freely. Use when the user says "mosaic", "assemble my fragments", "stitch these notes into a post", or provides a fragments file to turn into a finished piece. For writing from a topic with research, use article-factory; for prose from scratch, use the prose skill.
日本語の概要は準備中です。原文の説明を表示しています。
Extracts cfDNA fragmentomics features (DELFI genome-wide short/long ratios, WPS nucleosome positioning, Griffin GC-corrected accessibility profiles, end-motifs/MDS, OCF) for cancer detection and tissue-of-origin from plasma WGS. Centers on the nuclease-footprint reframe (every feature re-reads one nucleosome object), the mandatory GC correction, and the cross-protocol non-comparability that breaks naive classifiers. Runs FinaleToolkit (real CLI/Python, MIT) and the Griffin Snakemake pipeline; DELFI is a method, not a package. Use when deriving fragment-based signal from cfDNA, choosing a feature family for detection vs subtyping, or diagnosing why a fragmentomic model failed validation.
日本語の概要は準備中です。原文の説明を表示しています。
Android アプリ開発 (Kotlin) の画面遷移・Navigation リファレンス。 Jetpack Compose, androidx。Navigation 3 (stable), NavDisplay、 Navigation Compose, NavHost, composable, 型安全ルート、 Fragment ナビゲーション, NavHostFragment, Safe Args、 ディープリンク, App Links, assetlinks.json、 予測型戻る (OnBackPressedDispatcher)。
Treat context switches as the budget line they are — the switch census (how fragmented the week really is), the batching moves that consolidate scattered same-kind work, the calendar defrag that turns Swiss cheese into slabs, and the switch-cost line for saying no. Use when asked my day is fragmented to death, count my context switches, batch my meetings and reviews, or defend against calendar Swiss cheese. Produces the fragmentation census, the batching plan, the defrag moves, and the protective phrases.
日本語の概要は準備中です。原文の説明を表示しています。
Run a club, PTA, or association AGM that finishes on time and holds up later — the notice and agenda done right, a quorum plan, minutes that capture decisions not conversations, elections without awkwardness, and the follow-up that makes decisions real. Use when a volunteer says 'I have to run the AGM', 'what goes in the agenda', 'nobody comes to our meetings', or 'our elections are a mess'. Produces the notice, agenda, chair's script, minutes template, and quorum rescue plan.
日本語の概要は準備中です。原文の説明を表示しています。
Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.
日本語の概要は準備中です。原文の説明を表示しています。
Applies Geoffrey Moore's chasm-crossing strategy for B2B tech products moving from visionary early adopters to pragmatist mainstream. Use when a product has early traction but stalls before mainstream adoption, when planning a beachhead/niche strategy, when designing whole-product offerings, when positioning against established competitors, or when scaling from innovator usage to industry standard. Triggers include 'stuck between early adopters and mainstream', 'we need a beachhead', 'pragmatist customers won't buy', 'how do we go from 10 to 1000 customers'. NOT for PLG/freemium SaaS (Slack, Notion, Cursor), pure consumer apps, two-sided marketplaces, or AI-native products with bottoms-up viral adoption - their dynamics break the visionary-to-pragmatist sequence.
日本語の概要は準備中です。原文の説明を表示しています。
Grilling session that mines the user for fragments — heterogeneous nuggets of writing (claims, vignettes, sharp sentences, half-thoughts) — and appends them to a single document as raw material for a future article. Use when the user wants to develop ideas before imposing structure, or mentions "fragments", "ideate", or "raw material" for writing.
日本語の概要は準備中です。原文の説明を表示しています。
Pragmatics and communicative competence across languages -- speech acts (Austin/Searle), Grice's conversational maxims and implicature, politeness theory (Brown & Levinson), face-threatening acts, discourse structure, turn-taking, repair strategies, register and formality, cross-cultural communication, communicative strategies (circumlocution, approximation, appeal for assistance), and the gap between grammatical competence and communicative performance. Use when teaching communication skills, analyzing cross-cultural misunderstandings, building conversational fluency, or understanding why grammatically correct sentences can be pragmatically inappropriate.
日本語の概要は準備中です。原文の説明を表示しています。
> Persistent belief revision log wiring in-memory AGM BeliefSet to DuckDB time-travel storage. Triggers: belief revision, AGM postulates, time-travel query, belief history, AS-OF queries on propositions, persistent belief state, append-only belief log. >>>>>>> origin/main
日本語の概要は準備中です。原文の説明を表示しています。
Systematically interpret mass spectra to determine molecular formula, identify fragmentation pathways, and propose molecular structures. Covers ionization method assessment, molecular ion identification, isotope pattern analysis, common fragmentation losses, and purity evaluation.
日本語の概要は準備中です。原文の説明を表示しています。
Grilling session that mines the user for fragments — heterogeneous nuggets of writing (claims, vignettes, sharp sentences, half-thoughts) — and appends them to a single document as raw material for a future article. Use when the user wants to develop ideas before imposing structure, or mentions "fragments", "ideate", or "raw material" for writing.
日本語の概要は準備中です。原文の説明を表示しています。
Grilling session that mines the user for fragments — heterogeneous nuggets of writing (claims, vignettes, sharp sentences, half-thoughts) — and appends them to a single document as raw material for a future article. Use when the user wants to develop ideas before imposing structure, or mentions "fragments", "ideate", or "raw material" for writing.
日本語の概要は準備中です。原文の説明を表示しています。
Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.
日本語の概要は準備中です。原文の説明を表示しています。
Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.
日本語の概要は準備中です。原文の説明を表示しています。
Automate Datagma tasks via Rube MCP (Composio). Always search tools first for current schemas.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze Windows Shellbag (BagMRU) registry artifacts with SBECmd and Shellbags Explorer to reconstruct folder browsing activity and prove user interaction with directories, including removable media and network shares, even after the folders are deleted. Use when reconstructing a user's folder access history or proving access to a since-removed directory in DFIR work.
日本語の概要は準備中です。原文の説明を表示しています。
Automate Datagma tasks via Rube MCP (Composio). Always search tools first for current schemas.
日本語の概要は準備中です。原文の説明を表示しています。