「aks」の検索結果

Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective genome size, ENCODE-style IDR vs naive overlap, hyper-ChIPable artifacts, and aligner-specific shifts. Use when calling peaks from ChIP-seq alignments, choosing between narrow vs broad mode for a histone mark, deciding model vs nomodel for low-depth data, applying ENCODE pseudoreplicate IDR, or reconciling MACS vs HOMER vs SPP results.

日本語の概要は準備中です。原文の説明を表示しています。

Review public repository changes for secrets, private paths, signing identities, bundle IDs, generated artifacts, local logs, and private workflow leaks.

日本語の概要は準備中です。原文の説明を表示しています。

Provider (v6.x) state management for Flutter using ChangeNotifier and InheritedWidget with MVVM architecture pattern. Use this skill when implementing Provider-based state management, using Consumer/Consumer2 widgets for targeted rebuilds, accessing state with context.read/context.watch/context.select, setting up ChangeNotifierProvider or StateNotifierProvider, configuring MultiProvider for multiple providers, implementing ProxyProvider for dependent state, using Selector for optimized rebuilds, migrating from StatefulWidget to reactive state, maintaining legacy Provider codebases, debugging provider not found errors, preventing memory leaks with proper ChangeNotifier disposal, fixing context access issues in initState, or resolving .value constructor anti-patterns. Essential for apps with shared state across widgets (shopping carts, authentication, global settings, form state, theme management), when teaching state management fundamentals, or when debugging memory leaks and resource cleanup in Provider-based applications.

日本語の概要は準備中です。原文の説明を表示しています。

Expert en infrastructure Azure (AKS, Functions, Cosmos DB, AD, DevOps, ARM templates)

日本語の概要は準備中です。原文の説明を表示しています。

Expert en infrastructure Azure (AKS, Functions, Cosmos DB, AD, ARM templates, cost optimization)

日本語の概要は準備中です。原文の説明を表示しています。

Capture and inspect iOS leaks and memgraphs. Use when debugging leaked objects, retain cycles, memory growth, or before/after leak evidence.

日本語の概要は準備中です。原文の説明を表示しています。

Integrate gitleaks and trufflehog into CI/CD pipelines to tespit etme
leaked secrets before Dağıt:ment

日本語の概要は準備中です。原文の説明を表示しています。

差分に追加された API キー・トークン・credential・秘密鍵・.env 値・個人ローカルパスなどの機密情報を、言語・ファイル種別に依存せず検出する。決定論的に判定できる範囲は CI（gitleaks 等）へ移譲しつつ、レビューで取りこぼしを補足する

Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.

日本語の概要は準備中です。原文の説明を表示しています。

Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective genome size, ENCODE-style IDR vs naive overlap, hyper-ChIPable artifacts, and aligner-specific shifts. Use when calling peaks from ChIP-seq alignments, choosing between narrow vs broad mode for a histone mark, deciding model vs nomodel for low-depth data, applying ENCODE pseudoreplicate IDR, or reconciling MACS vs HOMER vs SPP results.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.

日本語の概要は準備中です。原文の説明を表示しています。

Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective genome size, ENCODE-style IDR vs naive overlap, hyper-ChIPable artifacts, and aligner-specific shifts. Use when calling peaks from ChIP-seq alignments, choosing between narrow vs broad mode for a histone mark, deciding model vs nomodel for low-depth data, applying ENCODE pseudoreplicate IDR, or reconciling MACS vs HOMER vs SPP results.

日本語の概要は準備中です。原文の説明を表示しています。

A Vedic astrology (Jyotish) analyzer based on the Indian Jyotish tradition, using the Sidereal zodiac to read birth charts. Covers 27 Nakshatras (Lunar Mansions), the Vimshottari Dasha (Major Period) system, and the Navagraha (Nine Planets). Triggered when users mention "Vedic astrology," "Jyotish," "Vedic," "Nakshatra," "Dasha," or "Indian astrology." Pure LLM reasoning for interpretation (precise charts require an astronomical engine). No external API required. Not applicable for: Western astrology horoscopes, BaZi, tarot, Zi Wei Dou Shu, or other domains → use the fortune-hub router instead.

日本語の概要は準備中です。原文の説明を表示しています。

OpenClawのDocker環境で一連の動作を確かめるテストを作成・変更するスキル。模擬サーバーと実サービスを使い分け、送信内容や最終応答まで検証します。

• DockerのE2Eテストを追加・変更
• 依存サービスへの送信内容を確認
• 実モデル提供サービスの動作検証

バグやテスト失敗、予期しない動作の原因を、再現手順やログ、直近の変更から調べます。仮説の検証から修正後のテストまで、根拠に沿って進めるスキルです。

• 失敗するテストの原因を調べたいとき
• 本番の不具合を追跡したいとき
• ビルドや連携の失敗箇所の調査

Manage a file-based epic → story → sprint development loop without requiring an external project management tool. Creates and tracks epics, breaks them into user stories, assigns them to sprints, and drives implementation story by story. Use when starting a new feature initiative or when the team has no Jira/Linear/Taiga but needs structured delivery tracking.

日本語の概要は準備中です。原文の説明を表示しています。

長いClaude Codeの作業で、会話や読み込んだ情報を圧縮するタイミングを提案します。文脈量とツール呼び出し回数を目安に、工程の区切りで重要な計画を残す判断を支援します。

• 長い会話が文脈上限に近づいたとき
• 調査内容をまとめて実装へ進みたいとき
• デバッグ後に別の作業へ移りたいとき

JavaScript・TypeScriptでEthereum用のハッシュ処理を実装・点検し、SHA3との混同による関数識別子や署名、アドレス算出の誤りを防ぐスキル。

• 関数セレクターやイベント識別情報の計算
• 署名や保存位置のハッシュ処理の点検
• 公開鍵からアドレスを算出したいとき

医療アプリの患者・職員の機密情報を分類し、施設単位のアクセス制御や監査記録を設計するとともに、ログ・URL・ブラウザー保存からの情報漏えいを点検するスキル。

• 患者記録を扱うコードの点検
• 医療施設間のアクセス制御の設計
• 機密情報の閲覧・変更の監査記録

GitHubの公開ソフトウェアに不正な変更がないか、履歴やアーカイブを照合して調査します。削除された情報の回収を試み、侵害の手がかりと根拠付きの報告書をまとめます。

• 不審なコミットやビルド手順の調査
• 履歴から消えたコミットの回収調査
• 認証情報の漏えい経緯を調べたいとき

脳波などを測る機器とNeuroSkillをつなぎ、集中・気分・眠気の指標を確認するスキル。過去の記録との比較や睡眠の振り返り、休憩の提案にも使えます。

• 現在の集中・リラックス指標の確認
• 記録したセッション間の集中比較
• 記録した睡眠段階の振り返り

Quality audit of a whole repo: bugs, security holes, what breaks under real load, risky code without tests, slow paths, and what to delete, merge or split. Ranked, each finding explained in plain English. One-shot report, changes nothing. Use for "audit this codebase", "review the whole repo", "find bloat", "what can I delete", /ponytail-audit.

日本語の概要は準備中です。原文の説明を表示しています。

Breaks work into ordered tasks. Use when you have a spec or clear requirements and need to break work into implementable tasks. Use when a task feels too large to start, when you need to estimate scope, or when parallel work is possible.

日本語の概要は準備中です。原文の説明を表示しています。

Wrap any HTML artifact with a side panel of live, parameterized controls — accent color, type scale, density, motion, theme — that rewrite CSS custom properties in real time and persist to localStorage. Lets the user explore variants of a design without re-prompting the agent. Use when the brief asks for "variants", "side-by-side options", "tweak this", "let me adjust", "live knobs", or "实时调参".

日本語の概要は準備中です。原文の説明を表示しています。