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Extends a mechanistic or association-level biomedical finding into a staged validation pathway that moves from descriptive evidence toward stronger functional support, mechanistic specificity, and clinical relevance. Use this skill when a user has a pathway, biomarker, cell-state, target, mechanism, or association finding and needs to decide what should be validated next, in what order, and which evidence layers are necessary versus optional. Do not default to maximal validation stacks. Build a structured validation ladder with a primary route, stronger upgrade route, and optional extensions.

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Designs a translational blueprint for moving a biomedical finding toward diagnosis, prognosis, treatment response prediction, patient stratification, or therapeutic development, with explicit translational milestones, validation thresholds, and feasibility-sensitive route framing.

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Designs cell-based and animal-based validation plans that translate computational, omics, biomarker, genetic, or clinical findings into experimentally testable validation routes. Always use this skill whenever a user wants to move from an in silico, statistical, or clinical association finding toward wet-lab validation using cell systems, organoid-like systems, xenograft or genetically relevant animal models. It should define the exact claim to test, separate mechanism-testing from association-support and translational-support goals, choose the best-fit model family, specify perturbation strategy, readouts, controls, sequencing of experiments, and four workload configurations (Lite / Standard / Advanced / Publication+) with one recommended primary plan. Never fabricate model availability, reagent availability, species relevance, assay feasibility, phenotype penetrance, expected effect sizes, validation success, or literature references.

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Temporarily disable the skill bus. Quick toggle to stop all subscriptions from firing without removing them.

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Format, create, and update concise XQUIC pull request bodies and review-state transitions. Use when asked to prepare or edit an alibaba/xquic PR body, create a draft PR from an already-pushed branch, update a PR after code changes pushed a new head, or move a validated draft toward review.

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Fail closed on published draft XQUIC code pull requests before ready-for-review state. Use when asked to pre-review a code PR or move it out of draft; verify current base-to-head code, protocol conformance, validation coverage, adversarial bad cases, hot-path performance, and memory safety in a five-part local report.

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Use when evaluating A-share short-term technical setups through Tang Nengtong's classic TA lens: volume-price relationships, moving average systems, breakout signals, and short-term momentum entry/exit.

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Use when evaluating Mark Minervini-style VCP setups: volatility contraction, tight price action, moving-average alignment, relative strength, breakout trigger, and structural stop placement.

日本語の概要は準備中です。原文の説明を表示しています。

Apply when sequencing an addition, refactor, or rewrite. Remove dead code, redundant validators, and stub references first, then build on the simpler base.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill for planning, testing, and safely executing PostgreSQL schema migrations — especially when working with production data or shared databases. **Trigger when user asks to:** - Test a schema migration before applying it to production - Add, remove, or rename columns safely on a live table - Change a column's data type without downtime - Add or drop indexes, constraints, or foreign keys on large tables - Understand which ALTER TABLE operations lock the table - Roll back a failed migration - Plan a zero-downtime migration strategy - Fork a database to test a migration safely **Keywords:** migration, schema change, ALTER TABLE, add column, drop column, rename column, change type, zero downtime, lock, AccessExclusiveLock, concurrent index, forking, rollback, backfill, deploy Covers: lock-level reference for every common DDL operation, safe migration patterns, fork-based testing, zero-downtime column changes, index creation, constraint addition, backfill strategies, pre/post-migration validation, and rollback planning.

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Create logos using AI image generation. Discuss style/ratio, generate variations, iterate with user feedback, crop, remove background, and export as SVG. Use when user wants to create a logo, icon, favicon, brand mark, mascot, emblem, or design a logo.

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Use this skill when the user wants a .pptx with smooth cross-slide animation — PowerPoint Morph transitions, Keynote-style continuous motion, shapes that grow / move / rotate as the slide advances. Trigger on: 'morph', 'morph transition', 'smooth transition', 'continuous animation across slides', 'Keynote-style transition', 'animated slide sequence', 'shape continuity across slides'. Output is a single .pptx. This skill is a scene layer on top of officecli-pptx — inherits every pptx v2 rule (visual floor, grid, palettes, connector canon, Delivery Gate 1–5a). DO NOT invoke for a generic deck, pitch deck, or board review without cross-slide motion — route those to officecli-pptx base or officecli-pitch-deck.

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Migrate Spring Security 5 to Spring Security 6 configuration. Use when removing WebSecurityConfigurerAdapter, replacing @EnableGlobalMethodSecurity with @EnableMethodSecurity, converting antMatchers to requestMatchers, or updating to lambda DSL configuration style. Covers SecurityFilterChain beans and authentication manager changes.

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Migrate Spring Boot 2.x applications to Spring Boot 3.x. Use when updating pom.xml versions, removing deprecated JAXB dependencies, upgrading Java to 17/21, or using OpenRewrite for automated migration. Covers dependency updates, version changes, and migration checklist.

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Combine multiple segment detection results into a unified list. Use when you need to merge segments from different detectors, prepare removal lists for video processing, or consolidate detection outputs.

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Migrate Hibernate 5 to Hibernate 6 with Spring Boot 3. Use when fixing HQL/JPQL query parsing issues, removing deprecated Criteria API, updating ID generation strategies, or diagnosing N+1 query behavior changes. Covers breaking changes, type mappings, and performance monitoring.

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Parse raw radar I/Q captures (CW or FMCW mmWave) and produce a cleaned 1-D slow-time signal ready for motion or vital-signs analysis. Use when Claude needs to read interleaved I/Q binary, do a Range FFT on FMCW chirps, remove static clutter, pick a subject range bin, extract phase with unwrapping, or debug why a radar pipeline is returning garbage. Not for pulse/UWB range gating, MIMO beamforming, or Doppler-only gesture radar.

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End-to-end pipeline for extracting heart rate (HR) and breathing rate (BR) from raw short-range radar I/Q captures — both continuous-wave (CW, 24 GHz clinical boards) and FMCW mmWave (60/77 GHz, TI IWR/AWR). Use when Claude needs to parse interleaved I/Q binary, do a Range FFT on FMCW chirps, remove static clutter, pick a subject range bin, extract phase with unwrapping, design HR/BR bandpass filters, pick a peak frequency via PSD, reject the HR second harmonic that often dominates the fundamental, or handle respiration-harmonic leakage on slow breathers. Not for pulse/UWB range gating, MIMO beamforming, Doppler-only gesture radar, arrhythmia detection, or multi-subject source separation.

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Data conditioning techniques for gravitational wave detector data. Use when preprocessing raw detector strain data before matched filtering, including high-pass filtering, resampling, removing filter wraparound artifacts, and estimating power spectral density (PSD). Works with PyCBC TimeSeries data.

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Use this skill when computing 3D step-response performance metrics for point-to-point drone flight — rise time, settling time, percent overshoot, and steady-state error based on Euclidean distance to the final target. Use instead of 1D stepinfo for any flight where all three position axes move simultaneously.

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Video editing with ffmpeg including cutting, trimming, concatenating segments, and re-encoding. Use when working with video files (.mp4, .mkv, .avi) for: removing segments, joining clips, extracting portions, or any video manipulation task.

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Process filler word annotations to generate video edit lists. Use when working with timestamp annotations for removing speech disfluencies (um, uh, like, you know) from audio/video content.

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Roadmap parsing, analysis, and mutation operations for ROADMAP.md. Handles phase and milestone lifecycle including add, insert (decimal), remove, complete, and requirements coverage analysis.

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Use this skill whenever an Agent needs to query, find, install, deploy, update, tag, adopt, diagnose, or safely remove Skills Hub content, including natural-language requests to manage Skills for Codex, Claude Code, Cursor, or another Agent. Always use the Skills Hub CLI workflow instead of editing Skill directories or the database.

日本語の概要は準備中です。原文の説明を表示しています。