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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.

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Standardizes molecular structures using the ChEMBL structure pipeline for normalization and parent selection plus RDKit rdMolStandardize for explicit custom steps such as tautomer canonicalization, salt/solvent stripping, charge handling, stereochemistry handling, mixture selection, and isotope normalization. Explicitly compares ChEMBL, canSARchem, RDKit, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

日本語の概要は準備中です。原文の説明を表示しています。

Decompose total effects into direct and indirect paths through mediators using mediation, CMAverse 4-way, HIMA/HIMA2 high-dimensional, BAMA, two-step / MVMR mediation, or double-ML medDML. Use when testing whether a molecular phenotype (expression, methylation, protein) mediates a treatment-outcome relationship, decomposing exposure-mediator interaction via VanderWeele 4-way, screening high-dimensional EWAS mediators, or running MR-based mediation when sequential ignorability is implausible.

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Implement, diagnose, or review SwiftUI motion using explicit and scoped implicit animations, springs, transitions, PhaseAnimator, KeyframeAnimator, matched geometry or navigation zoom, SF Symbol effects, and custom Animation types. Use when views should animate on state changes, insertion, removal, navigation, or multi-step choreography, or when motion must respect Reduce Motion and Swift concurrency.

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Access Core Motion accelerometer, gyroscope, magnetometer, device-motion, pedometer, activity-recognition, altitude, headphone motion, batched high-frequency workout motion, and water-submersion/depth data. Use when reading device sensors, counting steps, detecting walking/running/driving/cycling, tracking altitude, building motion interactions, handling AirPods head tracking, or implementing watchOS dive/depth features.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks for "ADHD output", "fewer output tokens", "short numbered steps", "limited working memory formatting", or explicitly invokes "adhd-output-style".

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Design and implement adaptive filters using DSP System Toolbox System objects. Use when working with adaptive filtering, system identification, noise cancellation, echo cancellation, active noise control (ANC), channel equalization, inverse system identification, or adaptive prediction. Covers dsp.LMSFilter, dsp.RLSFilter, dsp.FilteredXLMSFilter, dsp.FrequencyDomainAdaptiveFilter, dsp.AffineProjectionFilter, dsp.BlockLMSFilter, dsp.AdaptiveLatticeFilter, dsp.FastTransversalFilter, maxstep(), and algorithm selection for adaptive filtering problems. Replaces deprecated adaptfilt.* objects (removed R2020a).

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RF Toolbox and RF Blockset in MATLAB -- S-parameter I/O, network conversions (S/Z/Y/ABCD/T/H/G, mixed-mode), cascade/de-embedding, rfbudget analysis, circuit composition, matching networks, amplifier stability, mixer spurs, rational fitting, SI channels, baseband processing, Circuit Envelope simulation. Trigger: sparameters, Touchstone, .s2p, .s4p, rfplot, smithplot, rfparam, rfwrite, zparameters, yparameters, abcdparameters, s2sdd, cascadesparams, deembedsparams, rfbudget, noise figure, OIP3, IIP3, amplifier, modulator, nport, rffilter, attenuator, seriesRLC, shuntRLC, lcladder, txline, circuit, setports, clone, matchingnetwork, stabilityk, stabilitymu, powergain, gammams, gammaml, mixerIMT, OpenIF, rational, rationalfit, stepresp, txlineWRLGC, rf.Amplifier, rf.Mixer, rf.Filter, rf.Sparameter, rfsystem, RF Blockset.

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Build MATLAB apps from requirements to working code. Asks discovery questions (or skips them when the path is known), recommends UIFigure or UIHTML architecture, identifies layout archetype (Dashboard, Explorer, Tabbed, Wizard, Canvas), produces an implementation plan, and executes the build. For UIFigure apps, optionally serializes as App Designer (.mlapp or plain-text .m + .xml). Use when a user wants to build a MATLAB app, create a GUI, make an interactive tool, build a uifigure app, build a uihtml app, build an App Designer app, build a .mlapp app, build a plain-text App Designer app, or asks which approach to use. Also use when user describes spatial layout needs: dashboard, control panel, sidebar, tabs, wizard, stepper, canvas, workspace.

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Read BEFORE optimizing any MATLAB code for speed. Without this workflow, agents commonly optimize the wrong target, fabricate speedup claims without measurement, or introduce regressions. Guides the 7-step workflow: baseline, profile, identify, optimize, measure, verify, report.

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Analyze AMS waveform data using Mixed-Signal Blockset utilities: phase noise measurement, clock jitter, anti-aliased resampling, timing measurements, lock time, INL/DNL, ADC/DAC calibration, HSpice import. Use when analyzing time-domain voltage from PLL/VCO/clock simulations, measuring phase noise from variable-step solver output, computing jitter, or resampling non-uniform data.

日本語の概要は準備中です。原文の説明を表示しています。

Guides the 7-step MATLAB memory optimization workflow: baseline, profile, identify, optimize, measure, verify, report. Use when asked to reduce MATLAB memory usage, find memory bottlenecks, fix out-of-memory errors, or optimize memory-intensive code.

日本語の概要は準備中です。原文の説明を表示しています。

Expert guidance for simulating RoadRunner scenarios via the MATLAB programmatic API and Simulink co-simulation. Use when the user wants to run a simulation, step through a simulation, control actors during co-simulation, add observers, attach sensors, retrieve simulation logs, or read/write scenario variables. Covers simulateScenario, createSimulation, ScenarioSimulation set/get, ActorSimulation getAttribute/setAttribute, addObserver, SensorSimulation, Simulink co-sim blocks, and publishActorBehavior. NOT for project setup, scene building, scenario authoring, or trajectory export.

日本語の概要は準備中です。原文の説明を表示しています。

Generate kickoff artifacts for a multi-phase program: umbrella plan, Program Goal Charter, session-goal block, per-phase plan stubs, and the 7-step per-phase inner loop reference.

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Use when a managed library is ready to publish to GitHub and hand to teammates as an install command. Run the GitHub publishing steps, then return the exact shareable install command.

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Use this skill for Node.js backend AI via @cloudbase/node-sdk (>=3.16.0) — cloud functions, CloudRun, Express/Koa/NestJS, serverless APIs, scheduled jobs, LLM proxies, agent orchestration. The only SDK supporting image generation (ai.createImageModel + generateImage). Text via ai.createModel with groups cloudbase, hunyuan-exp, or custom-*; model ids (e.g. deepseek-v4-flash, glm-5, kimi-k2.6) go in the `model` field of generateText/streamText. MUST run two-step preflight before code — see body. NOT for browser/Web (use ai-model-web) or Mini Program (use ai-model-wechat).

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill for WeChat Mini Program AI via wx.cloud.extend.AI (小程序, wx.cloud apps). Covers generateText and streamText with callbacks (onText, onEvent, onFinish); streamText needs a data wrapper, generateText returns the raw response. Models via wx.cloud.extend.AI.createModel with groups hunyuan-exp (小程序成长计划), cloudbase (main managed), or custom-*; model id goes in the data wrapper `model` field. MUST run two-step preflight before code — see body. NOT for browser/Web (use ai-model-web), Node.js backend (use ai-model-nodejs), or image generation (use ai-model-nodejs).

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when a browser/Web app (React, Vue, Next, Nuxt, static sites, SPAs, dashboards, AI chat UI, 页面, 前端, 网页) needs AI models via @cloudbase/js-sdk. Default routing for Web/frontend AI — call directly from the browser, do NOT propose a Node.js proxy. Covers generateText and streamText; models via ai.createModel with groups cloudbase, hunyuan-exp, or custom-*, model id in the `model` field. MUST run two-step preflight before code — see body. NOT for Node.js backend (use ai-model-nodejs), Mini Program (use ai-model-wechat), or image generation (Node SDK only).

日本語の概要は準備中です。原文の説明を表示しています。

Transforms workflow to use Manus-style persistent markdown files for planning, progress tracking, and knowledge storage. Use when starting complex tasks, multi-step projects, research tasks, or when the user mentions planning, organizing work, tracking progress, or wants structured output.

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Post project updates to team chat, gather feedback, triage responses, and plan next steps. Adapts to available tools (chat, git, issues, tasks). First run discovers tools and saves a playbook; subsequent runs execute from the playbook. Trigger with 'team update', 'post update', 'sync with team', 'standup', 'check team chat', 'feedback loop', 'project update', 'what did the team say'.

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Walk through a live web app AS a real user to find usability + behavioural bugs that static reviews miss. REQUIRES proof of interaction (typing, clicking, sending, observing) before any verdict — a sweep that didn't interact terminates with verdict 'Incomplete'. Walks threads, exercises every element, runs the multi-pane stress matrix, visual polish sweep, component perfection checklist, automated a11y (axe-core), pragmatic performance budget (LCP/CLS/INP), scenario battery (11 scenarios), and stress recipes including the real-flavour data battery. Hard gates: console errors/warnings = 0, network 5xx = 0, layout collapse = 0, axe Critical/Serious = 0, perf budget green. Audit-the-audit meta-check rejects rushed reports. Each finding has reproduction steps, evidence path, and suspected code location. Trigger with 'ux audit', 'walkthrough', 'qa sweep', 'audit the app', 'dogfood this', 'check all pages', 'find what's broken', 'stress the UI'.

日本語の概要は準備中です。原文の説明を表示しています。

Versatile JavaScript animation engine for DOM, CSS, SVG, and JavaScript objects. Use when creating timeline-based animations, stagger effects, SVG morphing, keyframe sequences, or complex choreographed animations. Triggers on tasks involving Anime.js, timeline animations, staggered sequences, SVG path animations, morphing, or multi-step animation choreography. Alternative to GSAP for SVG-heavy animations and React-independent projects.

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Author, validate, and test Power Query M expressions in semantic model partitions. Automatically invoke when the user mentions "Power Query", "M code", "M expression", "partition expression", "query folding", or asks to "write Power Query", "fix Power Query", "test a partition", "preview partition data", "debug Power Query step", "optimize Power Query".

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When the user wants to add or optimize structured data (Schema.org, JSON-LD). Also use when the user mentions "schema," "structured data," "JSON-LD," "rich results," "rich snippets," "Google rich snippets," "featured snippet schema," "add schema to page," "missing structured data," "schema validation error," "Schema Markup Validator," "Google Rich Results Test," "FAQ schema," "Article schema," "Organization schema," "JobPosting," "HowTo," "Event," "SoftwareApplication," "BreadcrumbList," "WebSite," "Recipe," "Product," or "Dataset." For SERP feature types and zero-click patterns, use serp-features. For AI search visibility strategy (not markup), use generative-engine-optimization. For HowTo step sections (placement, copy, vs FAQ), use howto-section-generator.

日本語の概要は準備中です。原文の説明を表示しています。