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Epialleles are specific DNA methylation patterns that are mitotically and/or meiotically inherited. This package calls and reports cytosine methylation as well as frequencies of hypermethylated epialleles at the level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map (BAM) files as an input. Among other things, this package can also extract and visualise methylation patterns and assess allele specificity of methylation.

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Generate images and video through the Higgsfield MCP - text-to-image, text-to-video, and image-to-video with motion control across 100+ models. Generation draws real credits from the connected Higgsfield account; OAuth Connect via the dashboard MCP panel.

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Expand a hard-to-build niche list from ~10 known-good seed companies into a full qualified TAM. Seed fingerprinting (how do good-fit companies ACTUALLY show up in the company database's filters) → lookalike generation (Prospeo company_lookalike, Exa findSimilar, Parallel.ai entity search) → filter mining with a precision/volume scorecard → wide pull with auto-sharding → cheap-AI qualification → live-website verification → client transparency report. Use when a vertical list feels "too small" (medical groups, hedge funds, Medicare brokerages), when known good-fit companies don't show up in keyword searches, or when someone says "expand this list", "the TAM should be bigger", "find more companies like these".

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Plan shoot-ready Amazon product photography, listing image sets, infographics, lifestyle scenes, and production briefs. Use when a seller asks for an Amazon photo shot list, creative direction, image-pack plan, photography budget, DIY-versus-done-for-you decision, or handoff to a photographer or image-generation workflow. Do not use for listing copy or image-only performance auditing.

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Review generation strategy — Request a Review, follow-up emails, insert cards, Vine, early reviewer programs

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Builds lead generation systems using Alex Hormozi's Core Four framework (warm outreach, content, cold outreach, paid ads), lead magnets, and Rule of 100. Use when designing customer acquisition, scaling advertising, choosing marketing channels for revenue stage, building referral programs, or fixing low lead flow. Covers lead magnets, LTGP:CAC math, More Better New scaling, and Lead Getters (referrals, employees, agencies, affiliates).

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Build a User Generated Content (UGC) strategy — getting customers to create content, review generation, UGC briefs for creators, social campaigns, contest mechanics, legal rights management, and repurposing UGC in paid ads. Use when the user says "UGC", "user generated content", "get customers to create content", "customer content", "UGC ads", "UGC creators", "organic UGC", "UGC strategy", "how do we get customers to post about us", "brand hashtag", "UGC brief", "influencer UGC", "UGC for ads", "customer photos and videos", or wants to use real customer content to build trust and reduce content production costs.

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Full brand naming workflow for founders, agencies, and businesses. Use this skill whenever the user says "help me name this brand", "brand naming", "I need a name for", "name ideas for", "what should I call my brand/company/product", "naming a startup", "brand name suggestions", "help with naming", or shares a brand brief and asks for name options. Also triggers when the user shares existing name options and asks for feedback, evaluation, ranking, or scoring of those names. Auto-detects whether to run the full generation workflow or the evaluation workflow based on what the user provides. Always use this skill for any brand or product naming task — even if the user just casually mentions needing a name.

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Use when the user mentions Higgsfield Canvas, a node-based or node graph workspace, an infinite board/canvas, chaining generations into a pipeline, or wants to wire prompts → images → videos across models on one surface. Covers what Canvas is, the node categories, the seven models that run inside Canvas, the named canvas patterns (Simple Seedance, Extend Video, Image Edit, StoryBoard With Elements, Long Video fan-out), the build-free / generate-paid cost model, reusable templates, assets-as-nodes, and Shared Canvas live collaboration. Also trigger on 'Higgsfield ComfyUI alternative', 'node workflow', or 'connect nodes to build a scene/campaign'.

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Use when the user wants to generate a cinematic still image on Higgsfield, asks about shot framing, camera angle, or composition for image prompts, needs a specific shot type (close-up, wide shot, cowboy shot, etc.), or is working with [img] reference-based image generation. Covers distance & size shots, camera angles, and camera movement keywords optimized for AI image models (Soul 2.0, Nano Banana, Seedream, GPT Image, Flux, etc.).

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Use when the user asks about Moodboard, building a moodboard from reference images, curated moodboard presets, Soul Hex color transfer, applying a visual style direction to generations, or named moodboard styles like Y2K studio, Warm ambient, Theatrical light, Swag era, Flash editorial, Street photography, Asian nostalgia, Retro BW, Surreal solarization, etc.

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Use this skill AUTOMATICALLY before writing any Higgsfield prompt. Query the memory databases for relevant past failures and pre-apply known fixes before the user even hits generate. Triggers include: any request to write a Higgsfield prompt, any use of the higgsfield-prompt skill, any mention of generating a video or image on Higgsfield, any MCSLA prompt construction. This skill should run SILENTLY in the background — don't announce it, just apply what's known. If the databases are empty, skip silently and proceed with normal prompt generation.

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Seedance 2.5 prompt director — the omni-reference dialect. Routes the four generation modes (t2v / omni_reference / video_edit / video_extension), writes explicit @Image/@Video/@Audio reference roles with exclusions, stages 30-second videos into end-state beats, and covers video editing, forward/backward extension, first-last-frame and multi-keyframe control, storyboard grids, blockout rendering, and seamless transitions. Use whenever the user asks for a Seedance 2.5 prompt, mentions Seedance 2.5 / Dreamina / Jimeng, wants a clip longer than 15s on Seedance, wants to EDIT or EXTEND an existing video rather than generate a new one, or supplies more than a handful of image/video/audio references. For Seedance 2.0 (4K, `mode=fast`, or a genre hint) use higgsfield-seedance instead.

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Use when the user mentions the Higgsfield CLI (binaries `higgsfield` / `higgs` / `hf`, `higgsfield auth login`, `higgsfield generate create`, `higgsfield workflow`, the `@higgsfield/cli` npm package), the Higgsfield MCP custom connector (`mcp.higgsfield.ai/mcp`) or its bundled workflows (`get_workflow_instructions` — character-sheet, thumbnail-generation, ugc-* videos, faceless-video, narrator, subtitles, product-photoshoot, brand-asset-creation, ad-multiplier, video-editing / Higgsedit, website-builder-flow), Higgsfield's bundled skills repo (`higgsfield-ai/skills` — `higgsfield-generate`, `higgsfield-soul-id`, `higgsfield-product-photoshoot`, `higgsfield-brandkit`, `higgsfield-marketplace-cards`, `higgsfield-websites`, `higgsfield-video-explainer`, `higgsfield-youtube-thumbnail`, invoked as `/higgsfield:generate` etc.), or asks how this skill coexists with those tools (`do I need both`, `how does this work with the CLI/MCP/skills`, `should Higgsfield's workflow do this or you`).

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Use when the user asks about visual styles, aesthetics, color grades, film looks, or how to set the tone and atmosphere of a Higgsfield generation.

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Use when a Higgsfield generation fails, produces poor quality, looks wrong, doesn't match the prompt, or the user needs to fix or improve an output.

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Use when the user asks about Vibe Motion, motion graphics, kinetic typography, animated text, brand animations, logo animations, infographic animation, presentation animation, data-driven video, or prompt-to-motion-graphic workflows. Vibe Motion is fundamentally different from video generation — it creates deterministic code-based motion graphics, not AI-predicted pixel sequences. Use this when the text/logo must stay perfectly crisp and editable (code). For a cinematic/kinetic AI-generated video ad built from a storyboard (pixel render, native audio), use higgsfield-motion-design instead.

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Use this skill whenever the user asks anything about Higgsfield AI — writing or refining video/image prompts, choosing a model (Kling, Veo, Wan, Seedance, Minimax Hailuo, DoP, Soul, Nano Banana, Seedream, Flux, GPT Image, etc.), camera controls, named motion presets, Soul ID character consistency, Cinema Studio 2.5/3.0, Vibe Motion, troubleshooting failed generations, credit optimization, Photodump, or any mention of higgsfield.ai. Also trigger on generic "write me a video prompt" or "make me an AI video prompt" requests when Higgsfield is the user's configured platform.

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Build email capture landing pages (squeeze pages) as single self-contained HTML files. Triggers on: "build a squeeze page", "email capture page", "lead magnet page", "create an opt-in page", "build an email list page", "lead capture landing page", "create a freebie page", "build a page to collect emails", "opt-in landing page", "email signup page for [product/niche]", "create a lead magnet landing page", "build a page that captures emails before sending to affiliate offer".

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Generate multiple diverse solutions in parallel and select the best. Use for architecture decisions, code generation with multiple valid approaches, or creative tasks where exploring alternatives improves quality.

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Generate and download images through APIMart's asynchronous GPT-Image-2 API. Use when Codex needs APIMart image generation, GPT-Image-2 text-to-image, image-to-image with reference URLs or local image files, 1k/2k/4k output, aspect-ratio control, task polling, or saving APIMart image results locally.

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Create a scroll-controlled cinematic product website with rich motion (动效网站) from product materials, reference pages or videos, and brand assets. Use for requests involving 网站动效, immersive product landing pages where scrolling moves a continuous video forward and backward, multi-scene visual storytelling, direct image2.0 and Seedance 2.0 generation, scene-continuity review, or local preview packaging. Do not use for ordinary corporate sites, dashboards, ecommerce, blogs, or standalone promo videos without a website.

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Generate high-potential viral title candidates for content across WeChat public account articles, X/Twitter posts, YouTube videos, Bilibili videos, and similar content platforms. Use when the user needs headline/title ideation, batch title generation, platform-specific title adaptation, title-library reuse, title selection, title scoring, or a reusable title workflow based on universal formulas plus separated platform methods such as 公众号, X, YouTube, and B站.

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Guides the generation, reading, and updating of agentmap.md files. This skill ensures a consistent and up-to-date codebase map for AI Agents.

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