「health」の検索結果

Identify differentially bound regions across CLIP-seq conditions (knockdown vs control, treatment vs vehicle, disease vs healthy) using DEWSeq (sliding-window DESeq2), Flipper (Skipper-downstream), ASpeak, edgeR, or limma-voom. Use when computing condition-level changes in RBP binding intensity, choosing peak-level vs window-level vs crosslink-level testing, designing replicate experiments, or distinguishing biological binding shifts from technical confounders.

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Assesses genetic health of populations for conservation using effective population size estimation (GONE2 for recent Ne trajectory, NeEstimator for contemporary Ne, Stairway Plot 2 and PSMC for historical Ne), F-statistics (hierfstat), runs of homozygosity (detectRUNS), and genetic diversity metrics. Use when estimating effective population size, detecting inbreeding or bottlenecks, or assessing genetic diversity in threatened species from microsatellite or SNP data.

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Binder design campaign planning, monitoring, and troubleshooting. Use this skill when: (1) Planning a complete binder design campaign, (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.

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End-to-end EHR predictive modeling pipeline with PyHealth, covering dataset loading, task definition, model training, evaluation, calibration, and clinical interpretation.

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Internal — for Boundless team members only. Query Boundless broker telemetry tables on Redshift for prod/staging operational data. Use when the user asks about broker health, request evaluations, request completions, proving times, skip rates, telemetry data, or wants to run SQL against the telemetry database on live networks. Also covers historical telemetry through 2026-04-24 stored as Parquet archives in S3 (queried via DuckDB). Do NOT use for debugging local code changes, reviewing PRs, or investigating issues in the codebase itself.

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Internal — for Boundless team members only. Audit native ETH, market deposit, prover collateral, and distributor ZKC reserve balances for every operator-managed address (provers, distributor, order generators, signal). Use when the user wants to know which addresses need topping up, asks about the balance of provers/OGs/distributor/signal signers, says something is "running low" or "out of gas", or wants a periodic operational health check on operator wallets. Defaults to prod env (mainnets + prod testnets) — pass `--all` to also include staging.

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Find and synthesize research papers, whitepapers, PDFs, technical reports, and academic sources with Firecrawl Research, using semantic paper search, related-paper expansion, and in-body verification over Firecrawl's paper index — largely biomedical and life-science literature from PubMed, bioRxiv, and medRxiv, plus arXiv preprints in CS, physics, and math. Use when the user wants a literature review, systematic review, survey of studies, paper summary, research landscape, or sourced synthesis from scholarly and industry publications, including clinical, drug, gene, disease, epidemiology, and public-health topics. Prefer this over a general web-research workflow whenever the evidence base is published papers rather than web pages.

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Use this skill for all requirements-related work in a MATLAB MBSE project using the Requirements Toolbox (slreq). Covers creating and populating requirement sets, derivation links, test case requirements, verification coverage, reading and tracing links across requirement sets and models, checking link health, allocating requirements to components (Implement links), and building traceability reports. Trigger when the user asks about slreq API, slreqx files, slmx link files, outLinks/inLinks, traceability matrices, coverage analysis, broken links, or mapping requirements to architecture components. Use proactively for any requirements or traceability task.

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Discovery, download, and configuration hub for the entire aelf agent skill ecosystem. Use when the user wants to: (1) explore or list available aelf skills, (2) install/bootstrap aelf skills into Cursor, Claude Desktop, OpenClaw, Codex, or Claude Code, (3) route an aelf-related intent to the correct skill, (4) check health or audit installed skills, (5) onboard a new skill into the aelf ecosystem. Covers domains: Portkey CA wallet, Portkey EOA wallet, Awaken DEX, eForest NFT marketplace, AelfScan explorer, TomorrowDAO governance, aelf node interaction.

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Define, track, and act on QA metrics: test coverage percentage, flakiness rate, defect escape rate, MTTR, test execution time trends, automation ROI, quality gates, and SLAs for test suites. Includes metric formulas, realistic targets by company stage, and the action to take when each metric goes red. Use when: "QA metrics," "test metrics," "quality KPIs," "test health," "flakiness rate," "defect escape rate." Not for: building the dashboard UI (Allure/Grafana) — use qa-dashboard; measuring coverage gaps and mutation score — use coverage-analysis. Related: qa-dashboard, coverage-analysis, ci-cd-integration, release-readiness, quality-postmortem.

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Reviews and cleans up outdated documentation. Use periodically to maintain documentation health. Triggers on: review docs, clean up documentation, check for stale docs.

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Systematically QA test any application — web apps, native macOS apps, Electron apps, CLI tools, interactive REPLs, or anything on screen. Three modes: browser (chromux/CDP, fast, DOM-level), computer (MCP computer-use, screenshot + pixel clicks, any app), and cli (tmux, send-keys + capture-pane for interactive terminals). Auto-selects mode or accepts --browser / --computer / --cli override. Use when asked to "qa", "QA", "test this site", "test this app", "find bugs", "test and fix", "fix what's broken", "dogfood", "exploratory test", "bug hunt", "QA this app", "사이트 테스트", "앱 테스트", "브라우저 QA", "화면 보고 테스트해줘", "네이티브 앱 테스트", "screen test". Three tiers: Quick (critical/high only), Standard (+ medium), Exhaustive (+ cosmetic). Produces before/after health scores, fix evidence, and a ship-readiness summary.

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Configures Envoy, the high-performance C++ edge and service proxy, as an API gateway, load balancer or service mesh sidecar with L4/L7 routing, retries, circuit breaking, rate limiting, TLS and observability. Use when a user asks to set up Envoy, write an envoy.yaml, route traffic to backends, add health checks or rate limits, do a canary split, read Envoy admin stats, or understand the proxy behind Istio and Envoy Gateway.

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Google and Meta paid media account structure evaluation. Audits campaign/ad set architecture against conversion volume minimums, budget thresholds, and targeting overlap. Identifies over-segmentation, under-segmentation, budget fragmentation, and structural anti-patterns blocking algorithmic learning. Provides consolidation roadmaps with migration plans. Use when inheriting accounts, quarterly health checks, or before scaling budgets.

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Unified multi-platform paid media audit with parallel execution. Spawns scored audits for Google Ads, Meta Ads, and Microsoft Ads simultaneously, merges results into a budget-weighted aggregate health score (A-F), adds cross-platform analysis (budget allocation, tracking consistency, creative alignment, attribution overlap), and produces a prioritized action plan. Optionally generates a client-ready deck via pro-deck-builder. Use when the user asks for a full paid media audit, cross-platform review, or multi-channel ad assessment.

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Kubernetes is the operating system for the cloud. It schedules containers, handles networking, manages storage, and keeps your apps running. But K8s has a steep learning curve - abstractions on abstractions on abstractions. This skill covers the core concepts (Pods, Deployments, Services), production patterns (health checks, resource limits, HPA), and the gotchas that catch everyone (namespace confusion, service discovery, secret management). 2025 reality: You probably don't need to run your own cluster. Use managed K8s (EKS, GKE, AKS) unless you have a very good reason not to. Focus on writing good manifests, not managing etcd. Use when "kubernetes, k8s, kubectl, deployment manifest, helm chart, kustomize, pod, service yaml, ingress, horizontal pod autoscaler, hpa, kubernetes, k8s, containers, orchestration, devops, cloud-native, helm, kustomize" mentioned.

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World-class game UI design expertise combining the clarity of Nintendo's UI philosophy, the immersive diegetic interfaces of Dead Space and Metroid Prime, and the competitive readability principles from esports titles. Game UI is the invisible bridge between player intent and game response. Great game UI serves the player without breaking immersion. It communicates critical information at a glance during intense action, guides new players without patronizing veterans, and adapts gracefully from 4K monitors to handheld screens and from keyboard to touch to controller. The best game UI designers understand that every pixel of screen space is sacred - borrowed from the game world itself. Use when "game ui, game interface, hud design, heads up display, game menu, inventory ui, health bar, stamina bar, game hud, minimap, crosshair, reticle, button prompt, controller ui, gamepad navigation, diegetic interface, in-world ui, quest tracker, damage numbers, cooldown indicator, radial menu, game tooltip, game-ui, hud, game-interface, game-menu, controller-ui, diegetic, game-design, accessibility, console, mobile-games" mentioned.

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Acquisition is expensive. Retention is profitable. Customer success is the discipline of ensuring customers achieve their desired outcomes with your product - which leads to retention, expansion, and advocacy. This skill covers onboarding that activates, health scoring that predicts, retention plays that save, and expansion strategies that grow accounts. Use when "keywords, file_patterns, contexts, " mentioned.

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Expert in running the day-to-day operations of thriving communities. Covers moderation systems, onboarding flows, crisis management, scaling operations, and team management. The engine room that keeps communities healthy and safe. Use when "community operations, community moderation, community management, onboarding flow, crisis management, trust and safety, community team, " mentioned.

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Keeping codebases healthy, performant, and maintainable - refactoring, performance optimization, and technical debt managementUse when "refactor, optimize, performance, technical debt, cleanup, architecture, speed up, bundle size, memory leak, slow query, code smell, complexity, dead code, performance, refactoring, optimization, technical-debt, architecture, cleanup, bundle, memory" mentioned.

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Expert in growing and engaging communities sustainably. Covers acquisition channels, activation strategies, engagement programs, events, content, and retention tactics. Knows that healthy growth is about depth, not just numbers. Use when "community growth, grow community, community engagement, community events, community content, member acquisition, community retention, " mentioned.

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Expert in the human side of code review. Covers giving feedback that lands, receiving criticism gracefully, navigating disagreements, and building a healthy review culture. Understands that code review is as much about relationships as it is about code quality. Use when "code review, PR feedback, review comments, how to give feedback, harsh review, review culture, constructive criticism, " mentioned.

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Audit the vault for structural issues: unresolved wikilinks, orphan notes, dead-end notes, and Obsidian sync conflicts. Optional --fix flags create stubs or surface fixable issues.

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Use when the user explicitly asks to use the informed-patient skill to prepare for a medical appointment, organize symptoms before seeing a doctor, or evaluate the evidence behind a diagnosis or treatment. Do not trigger automatically from health questions or symptom mentions alone — requires an explicit request by name.

日本語の概要は準備中です。原文の説明を表示しています。