139mail
無料139邮箱IMAP/POP3操作技能。支持通过IMAP/POP3协议查看收件箱/未读邮件、发送邮件、搜索邮件、管理邮件、邮件分拣。首次使用需配置账号和授权码。当用户需要操作139邮箱(mail.10086.cn)时触发此技能。
日本語の概要は準備中です。原文の説明を表示しています。
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概要と使いどころ
139邮箱IMAP/POP3操作技能。支持通过IMAP/POP3协议查看收件箱/未读邮件、发送邮件、搜索邮件、管理邮件、邮件分拣。首次使用需配置账号和授权码。当用户需要操作139邮箱(mail.10086.cn)时触发此技能。
日本語の概要は準備中です。原文の説明を表示しています。
v09-audit-evidence-map
日本語の概要は準備中です。原文の説明を表示しています。
generic-session-resume-review-evidence-map
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive reference for inter-process communication mechanisms -- every way processes can talk on a computer. Covers sockets (TCP, UDP, Unix domain), WebSockets, SSE, pipes (named/anonymous), shared memory (mmap, shm_open), message queues, signals, D-Bus, XPC (macOS), gRPC, REST, stdin/stdout, file-based coordination, and clipboard. Performance benchmarks, platform availability, and code examples for each. Special focus on which IPC works best for AI agent coordination. Activate on: "IPC", "inter-process communication", "process communication", "how do I talk between processes", "Unix socket vs TCP", "shared memory", "named pipe", "WebSocket vs SSE", "gRPC vs REST", "agent coordination IPC", "XPC service", "message passing", "stdout pipe", "D-Bus", "mmap". NOT for: distributed systems design (use distributed-systems), network protocol design (use networking), message queue infrastructure like Kafka (use data-pipeline-engineer).
日本語の概要は準備中です。原文の説明を表示しています。
Strategic analyst that maps competitive landscapes, identifies white space opportunities, and provides positioning recommendations. Use when users need competitive analysis, market positioning strategy, differentiation tactics, or "how do I stand out?" guidance across any domain (portfolios, products, services). NOT for market size estimation or financial forecasting.
日本語の概要は準備中です。原文の説明を表示しています。
Map the most influential Reddit venues for a brand's AI visibility using Xpoz. Finds which subreddits and threads AI engines actually cite when answering buyer questions, where those questions get asked, and which live threads are worth answering. Use when asked to "get cited by AI through Reddit", "which subreddits matter for my brand", "Reddit influence map", "where should we engage on Reddit", or "why does ChatGPT cite Reddit for my category".
日本語の概要は準備中です。原文の説明を表示しています。
Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed dependence and metacluster stability, why embeddings are for looking not measuring, and median-heatmap annotation/merging. Use when discovering populations without predefined gates, choosing a clustering algorithm, selecting the number of metaclusters, or annotating clusters into cell types.
日本語の概要は準備中です。原文の説明を表示しています。
Detects m6A modifications from Oxford Nanopore direct-RNA-seq (DRS) signal using m6Anet (multiple-instance-learning over DRACH 5-mer signal). Covers the upstream pipeline (Dorado/Guppy basecalling -> minimap2 map-ont -> nanopolish eventalign -> m6anet dataprep -> m6anet inference), per-site vs per-read probability including the mod_ratio stoichiometry column, the DRACH-only constraint, minimum-coverage thresholds (20-50 reads/site), multi-condition comparison via xPore/Nanocompore/ELIGOS, Dorado native modification calling (RNA004, 2024+), and the cDNA-vs-DRS distinction (cDNA Nanopore CANNOT detect modifications). Use when calling m6A from ONT DRS without immunoprecipitation, choosing m6Anet vs xPore vs Nanocompore vs ELIGOS vs Dorado native, interpreting probability_modified vs mod_ratio vs per-read probabilities, deciding between m6Anet (known DRACH sites) and Dorado/Remora (genome-wide screening), pinning RNA002 vs RNA004 chemistry and basecaller versions, or troubleshooting eventalign/dataprep failures.
日本語の概要は準備中です。原文の説明を表示しています。
Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.
日本語の概要は準備中です。原文の説明を表示しています。
Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop, trackViewer, and ProteinPaint. Use when visualizing recurrent mutation hotspots on a single gene's protein, marking domain boundaries from UniProt/Pfam, comparing missense vs truncating distributions, or contrasting two cohorts on the same lollipop.
日本語の概要は準備中です。原文の説明を表示しています。
Creates DE-specific diagnostic and result visualizations using DESeq2/edgeR built-in functions and lightweight ggplot2 wrappers. Covers MA plot (with the shrunken-LFC compression effect), volcano (with the apeglm caveat that p-values are unchanged), PCA on VST/rlog (never raw counts), sample distance heatmaps, top-DE-gene heatmaps with the row-scaling trap, dispersion / BCV plot interpretation, p-value histogram diagnostics, plotCounts for individual genes, blind=TRUE vs FALSE rationale, and the n=3 visualization stake. Use when generating DE diagnostic plots, choosing VST vs rlog for visualization, troubleshooting suspicious plot patterns (shifted MA cloud, batch-dominated PCA, anti-conservative p-value histogram), or building a standard QC figure panel.
日本語の概要は準備中です。原文の説明を表示しています。
Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.
日本語の概要は準備中です。原文の説明を表示しています。
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
日本語の概要は準備中です。原文の説明を表示しています。
Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
日本語の概要は準備中です。原文の説明を表示しています。
Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
日本語の概要は準備中です。原文の説明を表示しています。
Set up parallel agent team for COMPLEX tasks. Creates worktree structure, generates ownership map, and initializes task queue. Use when orchestrator decomposes a task into parallel subtasks, or when asked to "set up team", "parallel setup", or "configure worktrees".
日本語の概要は準備中です。原文の説明を表示しています。
Test-to-requirement coverage mapping. Reads plan acceptance criteria and test files, produces a coverage gap report showing which requirements have no tests. Use during Phase 2 (Test) or Phase 4 (Review) to verify test completeness. Named after the Nyquist sampling theorem — sufficient test coverage prevents aliased (missed) requirements. NOT for running tests (see mk:testing); NOT for structural code review (see mk:review).
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes ticket complexity and maps dependencies against an existing codebase before sprint planning. Triggers on 'how complex is this ticket', 'what should we work on first', 'can we fit this in the sprint', 'tech review before planning', 'plan the sprint'. NOT for writing implementation plans (see mk:plan-creator); NOT for scope/ambition review (see mk:plan-ceo-review).
日本語の概要は準備中です。原文の説明を表示しています。
Fast parallel codebase scouting. Spawns multiple Explore subagents to search directories simultaneously, returning a consolidated file map with architecture fingerprint, complexity estimates, and routing suggestions. Use before planning, debugging, or any task spanning multiple directories. NOT for reading a single known file in depth (use Read directly); NOT for semantic find-usages or go-to-definition.
日本語の概要は準備中です。原文の説明を表示しています。
Read-only view of the execution roadmap. Lists every epic with its per-status tallies, nests the still-open rows beneath their epic, collapses wholly-finished epics into one rollup line, and closes by naming the next planned task in file order. Four verbs — `list` (the reader's view), `tasks` and `epics` (filterable row and epic queries), `next` (the first planned task). Invoke any time to see what is left to build. Not a workflow phase; never writes; never starts or commits work.
日本語の概要は準備中です。原文の説明を表示しています。
Geocode, POIs, routes, timezones via OpenStreetMap/OSRM.
日本語の概要は準備中です。原文の説明を表示しています。
Guides AI agents through Senzing entity resolution workflows using the Senzing MCP server. Covers data mapping to Senzing format, SDK code generation (Python, Java, C#, Rust, TypeScript/Node.js), documentation search, error troubleshooting, sample data access, reporting and visualization, SDK setup guides, and V3-to-V4 migration. Use when working with entity resolution, record matching, record linkage, deduplication, Senzing SDK integration, data mapping for Senzing ingestion, or troubleshooting Senzing error codes. Also use when the user mentions matching records across data sources, finding duplicate entities, identity resolution, master data management, or needs to resolve who is who across datasets.
日本語の概要は準備中です。原文の説明を表示しています。
The kpopper method: a knowledge record (GROUNDING.yaml) for work that gets revisited - what is known, where each piece came from, and what would make each conclusion wrong. Use when asked what kpopper is or how to keep a record, when choosing which kpopper skill fits a moment, or when no narrower one does. The occasions have their own skills: ground (read the record before answering), record (write what the work found), map (map existing materials), annotated-doc (a standalone HTML document with evidence), hub (the record's visual home), consolidate (hypotheses and merges), watch (background checks).
日本語の概要は準備中です。原文の説明を表示しています。
Generate or edit raster images when the task benefits from AI-created bitmap visuals such as photos, illustrations, textures, sprites, mockups, or transparent-background cutouts. Use when Codex should create a brand-new image, transform an existing image, or derive visual variants from references, and the output should be a bitmap asset rather than repo-native code or vector. Do not use when the task is better handled by editing existing SVG/vector/code-native assets, extending an established icon or logo system, or building the visual directly in HTML/CSS/canvas.
日本語の概要は準備中です。原文の説明を表示しています。