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概要と使いどころ
Med peer benchmarking: select actual biotech/pharma peers via the med universe (drug/indication overlap where possible) and compare med-relevant metrics — pipeline depth, catalyst density, cash position, margins, valuation multiples.
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Valuation methods analysis, DCF inputs, comparable multiples, P/E ratio, EV/EBITDA, price to book, valuation assumptions, relative valuation, intrinsic value, fair value estimate
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Standardized trade idea template, multi-method price target derivation PE and sales multiple approaches, GAAP to non-GAAP reconciliation, base bull bear scenario construction, investment thesis structuring, Zendesk-style case methodology
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Facilitate a structured conversation to define architecture principles for a repository. Supports multiple architecture styles: clean architecture (default), hexagonal / ports & adapters, modular monolith, or custom. Produces a formal architecture document that the corresponding atom will use. Use when setting up a new project, defining architecture standards, or when the user says 'setup architecture', 'define layers', 'architecture principles', 'help me define my architecture', 'hexagonal architecture', 'modular monolith', 'ports and adapters', or 'define my architecture style'.
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Facilitate a structured conversation to define language-specific idioms and patterns for a repository. Produces a language-idioms.md document consumed by multiple atoms to adapt pseudocode defaults to the project's language. Use when setting up a new project, switching languages, or when the user says 'setup language', 'define language idioms', 'configure language', 'language patterns', or 'adapt for Go/Rust/Python'.
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Protocol for handling ambiguous decisions and missing/conflicting knowledge during code generation, design, and review. Ensures AI surfaces genuine judgment calls with structured options and stops on hallucination risk instead of silently assuming. Use when a decision has multiple valid approaches, when facts are missing or contradictory, when the user asks 'what should we do here?', 'is this a judgment call?', 'should I ask about this?', 'am I guessing here?', 'what are the tradeoffs?', or when deciding between two reasonable architectural or design options. Also composed by molecules to define how judgment calls and clarification requests are surfaced and resolved.
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Generate persistent, explorable 3D worlds/environments with Marble by World Labs — from text, a single image, multiple images, video, or a 360 panorama, plus coarse-structure blocking with Chisel. Use this skill when a task needs a navigable 3D scene, VR/immersive backdrop, virtual-production environment, previz set, game-blockout, or web/engine-ready Gaussian splat or mesh, and you must choose an input mode, a Marble model, an export format, and a plan/API route, then review world quality. Covers the Marble web app and the World API, editing/expansion, output formats and what each supports downstream, import into Unity/Unreal/Blender/Houdini/web, pricing/credits, capability limits, and rights/licensing. Not for flat text-to-image, text-to-video clips, or real-time on-the-fly world models (Marble outputs are downloadable, static 3D environments).
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Generate and edit production images with xAI's first-party Grok Imagine API, including model selection, multiple references, synchronous and Batch API workflows, durable output handling, prompting, iteration, QA, cost and rate controls, privacy, safety, and rights review. Use for direct xAI image API integrations, not Grok video or third-party gateways.
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Generate, edit, composite, stream, and production-review still images with OpenAI GPT Image models. Use when an agent must choose between GPT Image 2 and legacy GPT Image/DALL-E integrations, select the Image API or Responses API, build prompts and reference-image workflows, use masks or multiple inputs, preserve identity or brand details, render in-image text, handle output files and partial images, estimate cost and rate limits, migrate deprecated image code, or apply OpenAI image safety, consent, privacy, provenance, and rights requirements. Do not use for OpenAI video or audio generation.
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Portable multi-source research with cross-source validation and an offline evidence ledger. Use for fact-checking, comprehensive research, or any question requiring multiple independent perspectives; work with the host agent's search tools and optionally add SandBase Tavily, Exa, Scholar, and Cloudsway coverage.
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Aggregate news from Google News, Tavily, and Exa to get comprehensive coverage of any topic. Cross-references multiple news sources, identifies publication velocity, detects emerging stories, and provides citation-ready news intelligence.
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Extract full transcripts and captions from YouTube videos for content analysis, summarization, note-taking, and repurposing. Supports multiple languages and auto-generated captions. Ideal for research, content creation, and accessibility workflows.
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Enrich any entity — companies, domains, emails, or people — with verified data from multiple sources. Combines Apollo, Strale, LinkedIn, and Akta data to fill gaps in your CRM, lead databases, or research datasets with production-quality enrichment.
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Enrich any company with comprehensive firmographic data including industry, size, revenue, funding, tech stack, beneficial ownership, and regulatory status. Combines multiple data sources for complete B2B company intelligence and due diligence.
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Per-CpG differential methylation testing from bisulfite sequencing count data or beta-value matrices. Covers beta and M-value computation, coverage filtering, statistical tests (Welch t-test, Mann-Whitney, limma, DSS beta-binomial), multiple testing correction, and effect size calculation. Use when comparing methylation at individual CpG sites between experimental groups from WGBS, RRBS, or targeted bisulfite sequencing.
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Detect sample contamination and cross-species reads using FastQ Screen. Screen reads against multiple reference genomes to identify bacterial, viral, adapter, or sample swap contamination. Use when suspecting cross-contamination or working with samples prone to microbial contamination.
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Extract, filter, annotate, and export differential expression results from DESeq2 or edgeR. Use for identifying significant genes, applying multiple testing corrections, adding gene annotations, and preparing results for downstream analysis. Use when filtering and exporting DE analysis results.
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Cell segmentation from multiplexed tissue images. Covers deep learning (Cellpose, Mesmer) and classical approaches for nuclear and whole-cell segmentation. Use when extracting single-cell data from IMC or MIBI images after preprocessing.
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End-to-end post-GWAS causal inference pipeline orchestrating heritability partitioning, genetic correlation, Mendelian randomization with CHP-aware sensitivity (CAUSE / LHC-MR), colocalization, fine-mapping with SuSiE / FOCUS, mediation, TWAS triangulation, cis-pQTL drug-target MR, effector-gene prioritization (L2G / PoPS / cS2G), and GenomicSEM common-factor GWAS. Use when triangulating causal inference across multiple complementary methods, prioritizing tissues via stratified LDSC, nominating or de-risking drug targets, mapping a lead SNP to a candidate effector gene, modeling shared genetic architecture across correlated traits, or producing a STROBE-MR-compliant publication-grade evidence battery from GWAS summary statistics.
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Detect and remove doublets (multiple cells captured in one droplet) from single-cell RNA-seq data. Uses Scrublet (Python), DoubletFinder (R), and scDblFinder (R). Essential QC step before clustering to avoid artificial cell populations. Use when identifying and removing doublets from scRNA-seq data.
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Analyzes community composition using constrained ordination (CCA, RDA, db-RDA), variance partitioning (varpart), indicator species analysis (indicspecies multipatt), and distance-based environmental gradient methods with vegan. Links species composition to environmental explanatory variables. Use when testing how environmental gradients structure species communities, identifying habitat indicator taxa, or partitioning explained variation among predictors. Not for basic unconstrained ordination and PERMANOVA (see microbiome/diversity-analysis).
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Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal. Use when removing unreliable columns or contaminating residues before phylogenetic inference, HMM building, or selection analysis.
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Process multiple sequence files in batch using Biopython. Use when working with many files, merging/splitting sequences, or automating file operations across directories.
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Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
日本語の概要は準備中です。原文の説明を表示しています。