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概要と使いどころ
ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate concordance. Use to assess experiment quality before downstream analysis. Use when assessing ChIP-seq data quality metrics.
日本語の概要は準備中です。原文の説明を表示しています。
Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when determining HLA genotype for transplant matching, neoantigen prediction, or pharmacogenomic screening.
日本語の概要は準備中です。原文の説明を表示しています。
Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and identifying local or global matches between DNA, RNA, or protein sequences.
日本語の概要は準備中です。原文の説明を表示しています。
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
日本語の概要は準備中です。原文の説明を表示しています。
Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
日本語の概要は準備中です。原文の説明を表示しています。
Query ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF. Use when determining clinical significance of variants for diagnostic or research purposes.
日本語の概要は準備中です。原文の説明を表示しています。
Extract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when analyzing chromatin organization, identifying nucleosome-free regions at promoters, or characterizing nucleosome occupancy patterns from ATAC-seq fragment size distributions.
日本語の概要は準備中です。原文の説明を表示しています。
Browse the web for any task — research topics, read articles, interact with web apps, fill forms, take screenshots, extract data, and test web pages. Use whenever a browser would be useful, not just when the user explicitly asks.
日本語の概要は準備中です。原文の説明を表示しています。
Apply Martin Fowler-inspired enterprise architecture rules when choosing layers, service layers, transaction scripts, domain models, repositories, mappers, or DTOs.
日本語の概要は準備中です。原文の説明を表示しています。
Quantifies crypto market regime health using free, keyless public data (CoinGecko + Binance funding). Generates a 0-100 composite score across 6 components (100 = risk-on) with a posture recommendation. No API key required. Use when user asks about crypto market conditions, whether it's alt season, BTC dominance, crypto risk-on vs risk-off, funding rates, or whether crypto exposure should be increased or reduced.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "analyze backlinks", "analyze my off-site signals", or "track AI traffic / ChatGPT / Perplexity referrals"; profiles referring domains, anchor-text mix, toxic links, and disavow candidates (backlinks mode) or isolates AI-assistant referral sessions in GA4/GSC/logs and reports their trend, landing pages, and AI-vs-organic conversion (ai-referrals mode). Not for internal links — use site-structure-optimizer; not for keyword positions — use rank-tracker; not for multi-metric stakeholder reports — use performance-monitor. 外链分析/反向链接/AI流量/AI引荐/ChatGPT流量/AI转化
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "build programmatic SEO pages", "generate pages at scale", "rank on a high-authority third-party site", "borrow domain authority", "build a vs / alternative page", "do local SEO", "optimize a Google Business Profile", or "fix NAP" — one page-build router with four modes: programmatic (template × dataset systems), parasite (barnacle publishing on Medium/Reddit/LinkedIn/GitHub), comparison (vs / alternative pages in four formats), and local (GBP + NAP + citations + location pages), each with its own thin/duplicate, honesty, or reputation-abuse guardrail. Not for finding what to target — use keyword-research or content-gap-analysis; not for drafting one standalone article — use content-writer; not for scoring a page for publish — use content-quality-auditor. 程序化SEO/批量页面/寄生SEO/借势权重/对比页/vs页/替代页/本地SEO/谷歌商家档案/NAP一致性
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "map the category narrative", "tear down how competitors tell their story", or "find the language conventions in our market"; produces a category narrative map — the dominant stories and points of view in the category, its language conventions and framing clichés, and a per-competitor narrative teardown (arc, claimed onlyness, proof pattern) plus how each rival's messaging has shifted over time (scraped copy vs archived copy). Not for the positioning canvas itself — use positioning-mapper; not for the beachhead's beliefs and objections — use audience-belief-mapper; not for SERP keyword targeting — use keyword-research; not for claim adjudication — use offer-claims-registry. 品类叙事/竞争叙事拆解/语言惯例/叙事演变
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "track where my emails are actually landing after I send", "read my seed-list inbox vs spam vs promotions results", "trend my Gmail Postmaster / Microsoft SNDS reputation", or "did placement drop after my last send"; produces a per-provider inbox/spam/promotions placement read, a domain/IP reputation trend from Postmaster + SNDS, a send-over-send delta with named regressions, and a reusable SEND-S placement snapshot on your own exported telemetry. Not for the pre-send SPF/DKIM/DMARC auth pre-flight — use deliverability-qa; not for computing the EQS or running the vetoes — use email-quality-auditor. 邮件收件箱落点监测/收件箱vs垃圾邮件/Postmaster声誉趋势
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "run a deliverability pre-flight before I send", "check my SPF/DKIM/DMARC/BIMI", "why am I landing in spam / promotions", or "score my sender reputation and list hygiene"; runs the ONE-TIME pre-send SEND S1 authentication pre-flight and builds the SEND S (Sender-integrity / Deliverability) evidence read — DNS + DMARC-RUA auth, domain/IP reputation, inbox placement, content/link/render, and point-in-time bounce/complaint hygiene — using Pass/Partial/Fail/Unknown/N/A states and scoring only at complete applicable coverage. Not for the recurring hygiene trend — use list-hygiene-monitor; not for final EQS or veto verdicts — use email-quality-auditor; not for segments/suppression lists — use list-segment-builder. 邮件送达率预检/SPF DKIM DMARC认证/发件域声誉
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "build a B2B cold-outbound sequence", "design reply-triage branching", "plan a domain warmup / sending throttle", or "make my outbound CAN-SPAM / opt-in compliant"; produces a multi-step outbound sequence with reply-triage branches (positive / objection / referral / not-now / opt-out), a warmup + send-throttle ramp schedule, jurisdiction opt-in/CAN-SPAM guardrails (guidance, not legal advice), and a SEND S-dimension read. Not for B2C lifecycle flows — use email-sequence-designer; not for the consent record — use consent-registry; not for computing EQS — use email-quality-auditor. B2B冷启动外联序列/回复分流/域名预热
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Guide for working in the grails-data-hibernate7 module, especially Hibernate 7 domain binding, mapping migration, generators, and integration tests. Use this when changing code or tests under grails-data-hibernate7.
日本語の概要は準備中です。原文の説明を表示しています。
Run an expert review against Nielsen's heuristics and domain criteria, with severity ratings. Use when you need findings without recruiting participants. For a facilitated team feedback session, use `design-critique` (design-ops).
日本語の概要は準備中です。原文の説明を表示しています。
Apply the Von Restorff Effect — the element that differs from its neighbours is the one remembered. Use when a single action must dominate. For overall ordering rather than single-element emphasis, use `visual-hierarchy`.
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Capture a user-reported defect as a durable GitHub issue written in the project's own domain language. Explores the codebase in parallel for context but never leaks file paths or line numbers into the issue. Use when the user reports a bug conversationally, runs a QA pass, or says "file an issue", "log this as a bug", "capture this".
日本語の概要は準備中です。原文の説明を表示しています。
Guides Amazon SES onboarding for domain-based email sending. Covers identity configuration, production access, an optional first test send, and troubleshooting setup, authentication, or sending failures. Use when setting up SES, resuming incomplete onboarding, or leaving the sandbox. Does not cover inbound email or Mail Manager, SMS/voice, WhatsApp, SNS, Pinpoint, or WorkMail.
日本語の概要は準備中です。原文の説明を表示しています。
Connects AI agents to remote Windows desktop applications on Amazon WorkSpaces Applications (AppStream 2.0) through the managed Agent Access MCP server, and guides reliable desktop automation. Covers connecting an agent to the MCP endpoint (SigV4, streaming URL, and Active Directory SAML/Domain Join), BLOCKING vs POLLING connect modes, the computer-use tools (screenshot, click, type, key, scroll), screenshot-budget and action-batching discipline, MCP tool forwarding (forwarded___ tools), session lifecycle and expire-on-delete, and troubleshooting connection errors. Use when building or debugging an agent that drives a remote Windows desktop or GUI application via WorkSpaces Applications / AppStream — including "dcv session not ready", "client_disconnected", 400 signing-region, POLLING/connection_status, SAML assertion, or forwarded tool questions. Not for Amazon WorkSpaces Personal/Core virtual desktops or general AppStream fleet administration unrelated to agent access.
日本語の概要は準備中です。原文の説明を表示しています。
Sets up CloudWatch observability for the first time - Omni (CloudWatch Application Observability) and classic CloudWatch. Omni: creating a Space or Domain; access grants (who has access, at what level) and access profiles bounding async alerts, integrations, or agents; instrumenting an app or AI agent with the plain ADOT SDK so traces reach Omni (Python/Node/Java/.NET on EC2/ECS/EKS/Lambda), incl. no-image-rebuild and .NET CoreCLR vars; ingesting Azure telemetry via the CloudWatch agent on an Azure VM or AKS; connecting Slack to a Space; whether GitHub or a custom MCP tool server (HTTP/stdio; API key, bearer, OAuth2) can be connected. CloudWatch: onboarding a service to Application Signals - ADOT auto-instrumentation, the amazon-cloudwatch-observability add-on, monitored service, reporting telemetry, ServiceEvents, CI/CD git/deployment metadata, Terraform/manifest edits. For using what is set up - queries, dashboards, alarms, Omni alerts, X-Ray, synthetics, Dynamic Instrumentation - use aws-observability.
日本語の概要は準備中です。原文の説明を表示しています。