1.4万 件 ・ 関連度順
概要と使いどころ
Update an existing GitHub Issue's description based on the issue number. Reads all issue comments and reflects any items not yet captured in the description. After refreshing the description, reviews it for remaining ambiguities or unclear requirements and posts any open questions as a follow-up 確認事項 comment.
日本語の概要は準備中です。原文の説明を表示しています。
Keep GPT-5.6 and other coding-agent work proportional to the request by locking scope, choosing the smallest sufficient implementation, matching verification to risk, and stopping when success is proven. Use for implementations, bug fixes, refactors, reviews, or maintenance where scope creep, speculative abstractions, unrelated cleanup, repeated test runs, unnecessary dependencies, or polishing beyond the request are risks.
日本語の概要は準備中です。原文の説明を表示しています。
Shakes your mental models with critical rigor, challenges assumptions, exposes blind spots, and provides multi-perspective insights as a strict thinking mentor. Deliberately breaks format conventions to stimulate genuine cognitive discomfort. Use when you want to stress-test an idea, shake your mental model, ask to challenge my assumptions, find blind spots, deepen my thinking, or request critical review with phrases like yusaburi or what do you think of this plan.
日本語の概要は準備中です。原文の説明を表示しています。
Survey related literature for a research topic or paper draft. Finds relevant papers, identifies citation gaps, and suggests key references. Use for "find related work", "survey papers on X", "what papers should I cite". 旧名 survey-literature。
日本語の概要は準備中です。原文の説明を表示しています。
論文・研究概要の体裁・形式を自動チェック。LaTeX(.tex)・Word(.docx)・PDF(.pdf)に対応。表記ゆれ・参考文献体裁・相互参照整合性・未記入セクション等を検出。1〜2ページの概要・梗概・アブストラクト（固定尺）は --fixed（またはページ数で自動判定）で紙面配分（参考文献が本文を圧迫していないか等）も診断する。提出直前の最終確認に使用。卒論・研究論文・学会投稿論文・研究概要すべてに対応。旧 abstract-format-check を統合。
Detect articulation gaps in documents using 5W analysis and provide concrete improvement suggestions. Identifies what's missing in explanation, not what's wrong. Default runs detection + improvement; use --check-only for detection only. 旧名 check-articulation。
日本語の概要は準備中です。原文の説明を表示しています。
研究概要・中間発表予稿の「研究としての筋」を、論理の鎖(L1背景→L2関連研究と限界→L3課題(差分)→L4仮説→L5評価→L6位置づけ)として1リンクずつ採点し、さらに端点間の整合(掲げた構成概念=旗と評価指標=物差しのズレ=construct validity)を照合するスキル。各文の綺麗さ(→articulation-check)でも汎用の弱点(→weakness-analyze)でもなく「リンク間が繋がっているか／旗と物差しが一致しているか」を見る。骨子・位置づけ・仮説・課題設定・研究の一貫性を見てほしい、research framing を見て、と言われたとき。旧名 research-framing-check。
Builds an interactive HTML dashboard visualizing the Agent Skills ecosystem by fetching live data from github.com/agentskills/agentskills. Use this skill whenever the user wants to explore, research, or visualize Skills architecture, the SKILL.md spec, ecosystem adoption, repo stats, or any Skills intelligence dashboard. Trigger when the user mentions "skills dashboard", "skills ecosystem", "skills architecture overview", "agentskills repo", or wants to analyze how different tools implement Agent Skills. Optimized for Perplexity Computer — Computer fetches all data live, no static files required.
日本語の概要は準備中です。原文の説明を表示しています。
Use OpenAI Codex CLI as a peer collaboration partner — same standing as Claude, not a one-shot tool. Bring Codex in EARLY (ideation, framing decisions, stuck moments), not only for late peer-review. Hand it strategic context (target, research, draft, reasoning), iterate conversationally over ~3-8 turns, converge before surfacing to the human. Invoke when the user says "check / iterate / ideate with Codex" or "ask Codex" — and proactively when stuck between two reasonable framings, pressure-testing a load-bearing claim or structure, or about to ask the human to pick between options two agents could resolve.
日本語の概要は準備中です。原文の説明を表示しています。
The default code-driven browser path for interactive browsing work: drives any browser from code with token-efficient a11y snapshots (57% smaller via compactSnapshot), ref-based clicks, coordinate control (CUA), viewport pinning, CAPTCHA solving (reCAPTCHA, Turnstile, hCaptcha, slider, OCR), Chrome MV3 APIs (tabs/bookmarks/history/downloads/topSites), network snoop (read API JSON instead of DOM), flight-recorder trace (jsonl + HAR + screenshots), OOPIF-aware snapshots, dialog policy, human handoff for login/OTP, device emulation, request routes, stealth via CloakBrowser as the default owned engine with zero exposed CDP ports, and an attached engine that drives the user's own signed-in browser through BrowserSkill (connectBrowserSkill, bskSnapshot, one-click onboarding via bskOnboard). MUST USE for interactive browser work: scraping, blocked/WAF/JS-rendered pages, logins, the user's logged-in sites and open tabs, extension popups, form filling, screenshots, web QA, CAPTCHAs. The ulw-research browsing lane runs on ultimate-browsing, not this skill.
日本語の概要は準備中です。原文の説明を表示しています。
Audit a browser fingerprint for internal contradictions with the liarjs CLI - canvas, WebGL, WebGL2, WebGPU, audio, 220 fonts, WebRTC and timezone probes, scored against the TLS/HTTP/ASN view of the same request. Use when asked to run a browser fingerprint test, see what a fingerprint looks like, check canvas or WebGL fingerprint stability, compare a spoofed profile against a real browser, or find out whether a browser profile is self-consistent.
日本語の概要は準備中です。原文の説明を表示しています。
Identify tumor neoantigens from somatic variants with pVACtools (pVACseq/pVACfuse/pVACbind/pVACvector/pVACview) for personalized cancer vaccines and checkpoint biomarkers. Encodes the field's hard truth that binding prediction is the easy, near-solved part and single-digit-percent PPV lives downstream — so it centers clonality/CCF, HLA LOH (the silent invalidator), expression, proximal-variant phasing, agretopicity/foreignness quality, and the predicted->presented->immunogenic validation tiers. Use when nominating vaccine targets, ranking neoantigens, or building a tumor-to-candidate pipeline. Binding details in mhc-binding-prediction; ranking in immunogenicity-scoring.
日本語の概要は準備中です。原文の説明を表示しています。
Detects A/B chromatin compartments from balanced Hi-C contact matrices via eigenvector decomposition of the distance-normalized, Pearson-correlated cis matrix with cooltools (eigs_cis), then orients (phases) the compartment eigenvector against a GC or gene-density track so the active (A) sign is not arbitrary. Covers the eigenvector-is-a-choice problem (per-arm view_df to remove the centromere gradient; picking the eigenvector by max correlation with activity, not by eigenvalue), GC phasing with bioframe.frac_gc, resolution choice (100kb-1Mb), saddle plots and saddle_strength for compartmentalization strength, the cohesin-loss-strengthens-compartments result, subcompartments (SNIPER/Calder/dcHiC), and cross-condition compartment switching. Use when calling A/B compartments, computing E1/eigenvectors, phasing the eigenvector, building saddle plots, choosing a compartment resolution, quantifying compartment strength, or comparing compartmentalization across conditions.
日本語の概要は準備中です。原文の説明を表示しています。
Orders and orients assembled contigs into chromosome-scale scaffolds from long-range linking data, inserting N-gap spacers (adds no sequence). Covers Hi-C/Omni-C scaffolding (YaHS, SALSA2, 3D-DNA/Juicer), Hi-C read-mapping prerequisites (map each end separately, no mate rescue, dedup, enzyme-aware), reading the contact map for misjoins/inversions/false-duplications, manual curation in Juicebox/PretextView (the VGP/DToL standard), reference-guided scaffolding (RagTag) and its karyotype-erasure hazard, genetic-map (ALLMAPS) and Bionano optical-map integration, chimera-breaking before scaffolding, gap-filling, and telomere/contig-vs-scaffold-N50 QC (tidk). Use when turning contigs into chromosomes with Hi-C, integrating a linkage map or optical map, choosing a scaffolder by available linking data, or judging whether a chromosome-scale assembly is trustworthy.
日本語の概要は準備中です。原文の説明を表示しています。
Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. Use when fetching UniProtKB entries, navigating the JSON schema, choosing between UniProtKB/UniRef/UniParc/Proteomes resources, deciding stream vs search endpoint for batch retrieval, running ID-mapping jobs with the async pattern, handling isoform suffixes, or filtering reviewed Swiss-Prot vs auto-annotated TrEMBL. Encodes the legacy URL migration (2022), the new JSON schema layout, and bulk-pull patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Build circular genome visualizations using circlize (R), pyCirclize (Python), or Circos (Perl CLI) with ideogram tracks, multi-data tracks (scatter, histogram, heatmap), chord/link arcs for interactions, and explicit circos.clear() between plots. Covers when circular is appropriate vs when Cartesian wins (Cleveland-McGill 1984), karyograms, and chromosome adjacency in chord diagrams. Use when adjacency on the circle conveys meaning — chromosome-level overview, structural variants, Hi-C interactions, cross-genome comparisons.
日本語の概要は準備中です。原文の説明を表示しています。
Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop, trackViewer, and ProteinPaint. Use when visualizing recurrent mutation hotspots on a single gene's protein, marking domain boundaries from UniProt/Pfam, comparing missense vs truncating distributions, or contrasting two cohorts on the same lollipop.
日本語の概要は準備中です。原文の説明を表示しています。
Visualize copy number profiles, segments, allele-specific tracks, and cohort patterns from CNVkit, GATK, ASCAT, FACETS, Sequenza, and other callers. Covers genome-wide and per-chromosome log2 scatter plots, B-allele-frequency/minor-allele-fraction tracks, ideograms, cohort heatmaps, circos views, and caller-native plots. Use when creating publication CNV figures, choosing which plot answers a given question, diagnosing a wrong diploid baseline visually, displaying loss of heterozygosity, or deciding what depth-only plots cannot reveal.
日本語の概要は準備中です。原文の説明を表示しています。
Constructs and validates polygenic risk scores using LDpred2-auto, SBayesRC, MegaPRS, PRS-CS, PROSPER, MUSSEL, BridgePRS, JointPRS, PRSmix, or PGS Catalog Calculator with ancestry-aware reference panels (HapMap3, UKB-LD), Pejaver-style calibration, and PRS-RS reporting standards. Use when computing PRS for cohorts, applying Whiffin-style absolute-risk transformation, assessing cross-ancestry portability (Martin 2017 / Ding 2023 continuous ancestry), or auditing PRS manuscripts against the 22-item PRS-RS reviewer checklist.
日本語の概要は準備中です。原文の説明を表示しています。
Detect horizontal gene transfer (HGT / LGT) using compositional methods (GC%, codon usage, tetranucleotide z-scores via SIGI-HMM, AlienHunter, IslandViewer 4, IslandPath-DIMOB), phylogenetic-incongruence methods (AvP, HGTphyloDetect, ALE / GeneRax / AleRax reconciliation, RANGER-DTL), and BLAST-distribution methods (HGTector v2, DarkHorse, Alien Index). Use when screening prokaryote genomes for genomic islands and HGT events, distinguishing HGT from incomplete lineage sorting / differential gene loss / hybridization, mapping donor lineages via phylogenetic placement, separating eukaryotic HGT from contamination, ruling out gBGC as a false signal, or quantifying DTL rates with ALE/GeneRax on bacterial trees.
日本語の概要は準備中です。原文の説明を表示しています。
Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, and applies the Patel et al 2024 *Nat Biotechnol* review's failure-mode framework to validate that normalization is correctly applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.
日本語の概要は準備中です。原文の説明を表示しています。
View, convert, and understand SAM/BAM/CRAM alignment files using samtools and pysam. Use when inspecting alignments, converting between formats, or understanding alignment file structure.
日本語の概要は準備中です。原文の説明を表示しています。
Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.
日本語の概要は準備中です。原文の説明を表示しています。
Run the API contract workflow for public interface changes, compatibility constraints, contract tests, documentation, and review.
日本語の概要は準備中です。原文の説明を表示しています。