6,892 件 ・ 関連度順
概要と使いどころ
外部データ取得と取り込み経路のセキュリティレビュー。JRA 以外のホストへ取りに行かせない URL 検証（SSRF）、スクレイピングの作法（User-Agent・リクエスト間隔・タイムアウト）、外部由来 HTML/JSON を無検証で DB に入れない、クエリを Kysely で組み立て生の SQL 文字列を増やさないこと、CLI 由来のファイルパスの扱い、生成物（*.db / data/extracted-*.json / data/jra-page.html）と .env をコミットさせないことを検証。Use when user says 'セキュリティレビュー', 'review security', 'セキュリティチェック', 'SSRF確認', or 'SQLインジェクション確認'.
教員向けの研究概要レビュー(research-review等の出力.md)を入力に、学生に直接渡せる「前向きだけど抑えめ・シンプル・self-contained・優先順つき」の中間発表コメント1枚に書き換えるスキル。厳しい分析を、学生が萎えず手を動かせる建設的な行動リストへ翻訳する層。レビュー結果を学生向けに書き換えて、学生向けコメントにして、と言われたとき、または research-review --student から連鎖呼び出しされる。
Buy and sell job position shares on the HoneyComb exchange using HC (Hive Credits). Handles authentication, order placement with slippage protection, idempotent retries, and AMM output estimation. Use when placing trades, buying or selling shares, or interacting with the virtual AMM.
日本語の概要は準備中です。原文の説明を表示しています。
Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.
日本語の概要は準備中です。原文の説明を表示しています。
Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.
日本語の概要は準備中です。原文の説明を表示しています。
Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.
日本語の概要は準備中です。原文の説明を表示しています。
Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.
日本語の概要は準備中です。原文の説明を表示しています。
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA, Crippen LogP, 3D shape) with explicit choice tables, bit vs count semantics, and partial-charge model selection. Use when featurizing molecules for similarity, QSAR, virtual screening, or ML, or selecting the correct fingerprint for a chemotype-aware task.
日本語の概要は準備中です。原文の説明を表示しています。
Performs structure-based virtual screening using AutoDock Vina, SMINA, GNINA (CNN scoring), and DiffDock-L hybrid workflows with explicit choice rules across rigid vs flexible docking, cross-docking vs self-docking, binding-site detection (P2Rank, fpocket), receptor preparation (PDB2PQR, PROPKA), ligand preparation (meeko, OpenBabel), and ultralarge-library screening (ZINC22, Enamine REAL). Use when screening chemical libraries against a protein target to find candidate binders, ranking docking poses, or selecting a docking workflow for a specific scenario.
日本語の概要は準備中です。原文の説明を表示しています。
Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.
日本語の概要は準備中です。原文の説明を表示しています。
Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal. Use when removing unreliable columns or contaminating residues before phylogenetic inference, HMM building, or selection analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Uncorrelated Evaluator — 4軸ルーブリック専門エージェント（functionality-reviewer・code-reviewer・design-reviewer・originality-reviewer）と security-reviewer を5並列実行し、成果物を多面的に独立評価します。PASS / NEEDS WORK / BLOCKED 判定を返します。Self-leniency 防止のため、実装エージェントのコンテキストを引き継がない新規エージェントとして起動します。「レビューして」「評価して」「実装を確認して」などのリクエストで起動します。
Audit a live page for accessibility issues, locate each WCAG violation precisely, and return a selector-grounded fix worklist without editing.
日本語の概要は準備中です。原文の説明を表示しています。
Premium "digital e-guide" template family — two patterns sharing a metadata-rich, editorial-archive identity: an infinite 3D-canvas portfolio (case/) for designer 作品集, and a 12-slide horizontal field-notes carousel (social-carousel.html) for long-form knowledge series.
日本語の概要は準備中です。原文の説明を表示しています。
Organiza, compara e seleciona entre as variações geradas, e publica a grade de comparação como Artifact para aprovação do time. Use quando o usuário disser "qual dessas", "comparar as variações", "escolher a melhor", "mostrar as opções", "montar grade de aprovação", ou após qualquer lote de geração. Selecionar é trabalho, não detalhe.
日本語の概要は準備中です。原文の説明を表示しています。
Escreve copy para redes sociais — post avulso, carrossel, thread e legenda — respeitando limite, formato e cultura de cada plataforma. Use quando o usuário disser "post para", "legenda", "conteúdo para LinkedIn", "carrossel", "social media", "adaptar para as redes", "texto do Instagram". Para o gancho isolado ver copy-hooks; para derivar de material existente ver copy-repurpose.
日本語の概要は準備中です。原文の説明を表示しています。
Onboarding tour with AdwCarousel and navigation dots, skippable welcome screens. Use when adding a first-run tour or feature showcase to a GNOME app.
日本語の概要は準備中です。原文の説明を表示しています。
When the user wants to create or optimize in-app paywalls, upgrade screens, upsell modals, or feature gates. Also use when the user mentions "paywall," "upgrade screen," "upgrade modal," "upsell," "feature gate," "convert free to paid," "freemium conversion," "trial expiration screen," "limit reached screen," "plan upgrade prompt," "in-app pricing," "free users won't upgrade," "trial to paid conversion," or "how do I get users to pay." Use this for any in-product moment where you're asking users to upgrade. Distinct from public pricing pages (see page-cro) — this focuses on in-product upgrade moments where the user has already experienced value. For pricing decisions, see pricing-strategy.
日本語の概要は準備中です。原文の説明を表示しています。
Elite website image-to-code skill for Codex. For visually important web tasks, it must first generate the design image(s) itself, deeply analyze them, then implement the website to match them as closely as possible. In Codex, it must prefer large, readable, section-specific images instead of tiny compressed boards, generate fresh standalone images for sections or detail views instead of cropping old ones, avoid lazy under-generation, avoid cards-inside-cards-inside-cards UI, and keep the hero clean, spacious, readable, and visible on a small laptop.
日本語の概要は準備中です。原文の説明を表示しています。
UI 資產切件與候選收斂 SKILL — 從使用者提供的整頁 UI、2K 母圖、panel sheet 或單張素材，自動執行全切、auto-classify、auto-pick、temp/selected 分流、背景裁切、透明化與 post-process。USE FOR: 切出 panel / cap / badge / glyph / noise 候選、把未挑選切片集中到 temp 可一次清掃、把高信心候選升到 selected、再接 trim-png-by-background.js / postprocess-ui-asset.js。DO NOT USE FOR: runtime 畫面驗收（用 ui-runtime-verify）、純 icon 規格設計（用 UI-icon workflow）、單純修改 layout/skin JSON。
日本語の概要は準備中です。原文の説明を表示しています。
Idiomatic Go concurrency - sync primitives, channel semantics, the select statement, and the standard channel patterns (cancellation/done-channel, fan-out/fan-in, pipeline, or-done, context, worker-pool). Use when writing or reviewing Go that spawns goroutines, shares state, or coordinates over channels, even if the user never says "concurrency" - e.g. data races, deadlocks, goroutine leaks, sync/context/select usage, or "make this parallel". Distilled from luk4z7/go-concurrency-guide.
日本語の概要は準備中です。原文の説明を表示しています。
Design a self-improvement loop for a shipped product's AI agents — production traces feed evals, evals feed improvement proposals (prompts, playbooks, retrieval configs), and a human approval gate promotes changes with rollback. Technique-agnostic: chooses per project between ACE-style evolving playbooks, GEPA/MIPROv2 offline optimization, or simple eval-driven iteration via references/techniques.md. Load when the user asks to make my product's agents self-improving, learn from production traces, add a learning loop, evolve prompts or playbooks safely, promote agent improvements, or GEPA-style optimization. NOT harness-evolution (that improves the coding agent), NOT experimentation (product A/B tests), NOT agent-run-retro (dev-phase manual retros — this skill is the production-scale continuation).
日本語の概要は準備中です。原文の説明を表示しています。
Plan which model tier handles which work BEFORE execution begins — a high-cognition model deeply understands the problem, lays the foundations, then emits a modular plan assigning each module the cheapest tier that can safely execute it, with escalation tripwires and one-way-door protection. Advisory only: it announces "next module → tier X / model Y" at each boundary and the HUMAN switches models — harnesses like Cursor cannot switch mid-run. Load when the user asks which model to use, wants a model plan, model tiers, model-tier routing, assign models to tasks or modules, says "cheap model got stuck", "which model for this task", "cost-efficient model choice", or when implementation-plan / problem-to-plan need a model: tier column. NOT dynamic-routing (plan-path selection after failure) — this skill assigns cognition tiers to work.
日本語の概要は準備中です。原文の説明を表示しています。
Select alternative execution paths when a plan step fails — branch on outcomes instead of blind retry. Load when a structured plan step fails, an unexpected observation arrives, or the user asks what to try next after an error. Also triggers on "try another approach", "route around this failure", "replan on failure", "if X fails try Y", or outcome-based branching during multi-step work. Pairs with structured-planning and debug-and-fix. Does not replace root-cause debugging — adds plan-level path selection.
日本語の概要は準備中です。原文の説明を表示しています。