「optimization」の検索結果

Database schema design, migrations, query optimization with SQL, Exposed ORM, Flyway. Use for database, migration, schema, sql, flyway tags. Provides migration patterns, validation commands, rollback strategies.

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Quantum computing framework for building, simulating, optimizing, and executing quantum circuits. Use this skill when working with quantum algorithms, quantum circuit design, quantum simulation (noiseless or noisy), running on quantum hardware (Google, IonQ, AQT, Pasqal), circuit optimization and compilation, noise modeling and characterization, or quantum experiments and benchmarking (VQE, QAOA, QPE, randomized benchmarking).

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Tracks LLM token consumption and usage metrics for billing, monitoring, and optimization. Use this to log token usage, calculate costs, generate invoices, and understand which agents or users consume the most resources.

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Optimize cloud costs through resource rightsizing, tagging strategies, reserved instances, and spending analysis. Use when reducing cloud expenses, analyzing infrastructure costs, or implementing cost governance policies.

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Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

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Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

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Optimize AgentDB performance with quantization (4-32x memory reduction), HNSW indexing (150x faster search), caching, and batch operations. Use when optimizing memory usage, improving search speed, or scaling to millions of vectors.

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Operational skill hub for LLM system architecture, evaluation, deployment, and optimization (modern production standards). Links to specialized skills for prompts, RAG, agents, and safety. Integrates recent advances: PEFT/LoRA fine-tuning, hybrid RAG handoff (see dedicated skill), vLLM 24x throughput, multi-layered security (90%+ bypass for single-layer), automated drift detection (18-second response), and CI/CD-aligned evaluation.

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Collection of AWS development skills covering CDK infrastructure as code, cost optimization, and serverless/event-driven architectures with integrated MCP servers.

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Postgres performance optimization and best practices from Supabase. Use this skill when writing, reviewing, or optimizing Postgres queries, schema designs, or database configurations.

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PostgreSQL-specific code review assistant focusing on PostgreSQL best practices, anti-patterns, and unique quality standards. Covers JSONB operations, array usage, custom types, schema design, function optimization, and PostgreSQL-exclusive security features like Row Level Security (RLS).

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PostgreSQL-specific development assistant focusing on unique PostgreSQL features, advanced data types, and PostgreSQL-exclusive capabilities. Covers JSONB operations, array types, custom types, range/geometric types, full-text search, window functions, and PostgreSQL extensions ecosystem.

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AI-assisted pair programming with multiple modes (driver/navigator/switch), real-time verification, quality monitoring, and comprehensive testing. Supports TDD, debugging, refactoring, and learning sessions. Features automatic role switching, continuous code review, security scanning, and performance optimization with truth-score verification.

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Implement adaptive learning with ReasoningBank for pattern recognition, strategy optimization, and continuous improvement. Use when building self-learning agents, optimizing workflows, or implementing meta-cognitive systems.

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Optimize AgentDB performance with quantization (4-32x memory reduction), HNSW indexing (150x faster search), caching, and batch operations. Use when optimizing memory usage, improving search speed, or scaling to millions of vectors.

日本語の概要は準備中です。原文の説明を表示しています。

Turborepo monorepo build system guidance. Triggers on: turbo.json, task pipelines, dependsOn, caching, remote cache, the "turbo" CLI, --filter, --affected, CI optimization, environment variables, internal packages, monorepo structure/best practices, and boundaries. Use when user: configures tasks/workflows/pipelines, creates packages, sets up monorepo, shares code between apps, runs changed/affected packages, debugs cache, or has apps/packages directories.

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Use for Vercel cost and performance optimization on deployed projects, especially Next.js, SvelteKit, Nuxt, and limited Astro apps. Collect Vercel metrics, usage, project config, and code scan results first; investigate only metric-backed candidates; produce ranked recommendations grounded in verified files and version-aware Vercel/framework docs. Trigger for Vercel bill reduction, slow or expensive routes, caching opportunities, Function Invocations, Build Minutes, Fast Data Transfer, Core Web Vitals, Bot Management, Fluid compute, or cost breakdown requests.

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TypeScript and JavaScript expert with deep knowledge of type-level programming, performance optimization, monorepo management, migration strategies, and modern tooling. Use PROACTIVELY for any TypeScript/JavaScript issues including complex type gymnastics, build performance, debugging, and architectural decisions. If a specialized expert is a better fit, I will recommend switching and stop.

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Cloud quantum chemistry platform with Python SDK. Run geometry optimization, conformer generation, torsional scans, and energy minimization (DFT/semiempirical), and retrieve properties (dipole, partial charges, frontier orbitals) — no local QC software or HPC needed.

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Constraint-based (COBRA) analysis of genome-scale metabolic models: FBA, FVA, knockouts, flux sampling, production envelopes, gapfilling, media optimization. Use for strain design, essential gene ID, flux analysis. For kinetic modeling use tellurium; for visualization use Escher.

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smina molecular docking CLI. AutoDock Vina fork with customizable scoring functions, native SDF/MOL2/PDB ligand input, autoboxing, local energy minimization, and per-atom score breakdowns. Pipeline: receptor PDBQT prep -> ligand prep (RDKit/OpenBabel) -> dock via autobox or explicit grid -> rescore/minimize with custom scoring -> rank poses by affinity. Choose smina over Vina when you need custom scoring terms (--custom_scoring), local optimization of an existing pose (--local_only), per-atom contributions (--atom_term_data), or SDF/MOL2 ligands without manual PDBQT conversion. For unknown binding sites use diffdock; for the Python-bindings/Vinardo workflow use autodock-vina-docking.

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MATLAB/GNU Octave numerical computing: matrices, linear algebra, ODEs, signal processing, optimization, statistics, scientific visualization. MATLAB-syntax examples run on both. For Python use numpy/scipy; for statistical modeling use statsmodels.

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Python framework for single- and multi-objective optimization with evolutionary algorithms. Define vectorized objectives and constraints; solve with NSGA-II, NSGA-III, MOEA/D, GAs, or differential evolution. Analyze Pareto fronts, visualize trade-offs, customize operators and callbacks. For engineering design, hyperparameter search, and conflicting objectives. Alternatives: scipy.optimize (single-objective, gradient), platypus, jMetalPy (Java).

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API + Python SDK for ordering cell-free protein expression and binding assays. Submit sequences for expression (10–100 µg), measure binding affinity (KD) against targets, track status, and retrieve results programmatically — no wet-lab setup. Built for ML-guided directed evolution and antibody/nanobody optimization. Requires Adaptyv account and API key.

日本語の概要は準備中です。原文の説明を表示しています。