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Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Generate hand-drawn 16:9 article illustrations with the Grav character IP, sparse annotations, and absurd but clear visual metaphors.

日本語の概要は準備中です。原文の説明を表示しています。

Start AEM Workflows on AEM as a Cloud Service using all available triggering mechanisms. Use when starting workflows manually via the Timeline UI, programmatically via WorkflowSession.startWorkflow(), via the HTTP Workflow API, through Manage Publication, or passing initial metadata and payload to a workflow instance.

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The Block Collection and Block Party are repositories for existing AEM blocks, build tools, code snippets, integration patterns, plugins, and more. Use this skill anytime you are developing something and want to find a reference to use as a starting point.

日本語の概要は準備中です。原文の説明を表示しています。

Local ComfyUI / Stable Diffusion SDXL partial-asset generation workflow. Use for ComfyUI, stable diffusion, SDXL, LoRA, badge, cap, plaque, panel fragment, UCUF partial asset exploration, and saving generated PNGs from the local backend.

日本語の概要は準備中です。原文の説明を表示しています。

DALL-E 3 image generation workflow for this repo MCP server. Use for dalle3, DALL-E 3, OpenAI image generation, concept art, UCUF reference exploration, UI icon, badge, card art, prompt drafting, and saving generated images to local files under artifacts/ui-source or other workspace paths.

日本語の概要は準備中です。原文の説明を表示しています。

GPT Image 2 image generation workflow for this repo MCP server. Use for gpt-image-2, OpenAI image generation, concept art, UCUF reference exploration, UI icon, badge, card art, prompt drafting, transparent-background asset drafts, and saving generated images to local files under artifacts/ui-source or other workspace paths.

日本語の概要は準備中です。原文の説明を表示しています。

Orchestrator for the pre-decision business-idea lifecycle — generate ideas, model them, evaluate them, validate them with customers, and only then hand off to product-soul / brainstorming. Routes through `idea-generation`, `business-modeling`, `idea-evaluation`, and `customer-discovery`. Load when the user asks to explore business ideas, find a startup idea, evaluate a venture, validate an idea, says "what business should I start", "should I build this", "is this a good business", "I have a startup idea", "evaluate this venture", "model this business", "validate this idea", "Mom Test this", "Lean Canvas this", "Business Model Canvas", "Value Proposition Canvas", "go/no-go on this idea". Pre-decision suite — once one idea is committed, hands off to `product-soul`. Does NOT design features (use `brainstorming`) or audit built products (use `reality-check`).

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Guided first-run that produces a real verified win in under five minutes using the skill library on a seeded offline fixture. Load when a new user asks how to start, run the demo, try agent-loom, or get a quick win. Also triggers on "quickstart", "first run", "demo agent-loom", "try the skills", or onboarding to the library. Zero external credentials required. Idempotent — safe to run multiple times.

日本語の概要は準備中です。原文の説明を表示しています。

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user wants to visualize data. It intelligently selects the most suitable chart type from 26 available options, extracts parameters based on detailed specifications, and generates a chart image using a JavaScript script.

日本語の概要は準備中です。原文の説明を表示しています。

Create beautiful visual art in .png and .pdf documents using design philosophy. You should use this skill when the user asks to create a poster, piece of art, design, or other static piece. Create original visual designs, never copying existing artists' work to avoid copyright violations.

日本語の概要は準備中です。原文の説明を表示しています。

Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes species-environment relationships with constrained ordination (CCA, RDA, db-RDA), variance partitioning, indicator species (indicspecies IndVal.g group-equalized), PERMANOVA paired MANDATORILY with PERMDISP (Anderson & Walsh 2013; dispersion confounds centroid tests), Joint Species Distribution Models (HMSC, sjSDM, gjam) with explicit rejection of "residual covariance equals biotic interaction", phylogenetic community ecology (SES_MPD/MNTD), trait-environment via RLQ + fourth-corner with corrected modeltype=6 (Dray 2014), bipartite network metrics (NODF, modularity) with curveball null (Strona 2014), and Mantel-test replacements (dbRDA, GDM) for spatial data. Use when testing how environmental gradients structure communities, identifying habitat indicator taxa, partitioning variance among predictors, deciding whether PERMANOVA significance is location vs dispersion, picking among HMSC/sjSDM/gjam, or replacing Mantel tests for landscape data.

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Assigns pathogen lineages (SARS-CoV-2 Pangolin via UShER mode; Nextclade clade + QC; pango-designation alias_key.json resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage fitness modelling (Wenseleers / Bedford-Figgins multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data version pinning (mandatory for reproducibility), Nextclade dataset versioning (lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme version churn (V3 / V4 / V4.1 / V5.3.2 / Midnight 1200) with documented dropout regions, recombinant X-prefix Pango designation lag, GISAID vs INSDC dual-deposition tensions, and the Karthikeyan 2022 wastewater early-detection signal with explicit reproducibility caveats. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater pooled samples into lineage frequencies with Freyja, tracking lineage frequencies and growth advantages over time, pinning pangolin-data / Nextclade dataset versions for reproducibility, handling ARTIC primer dropouts (V4.1 amplicons 64 / 76 / 88-90), or running variant surveillance for SARS-CoV-2 / influenza / Mpox / RSV / H5N1 / measles.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a driver has been disqualified or is at risk of disqualification — major offense convictions (DUI, leaving the scene, drug trafficking with CMV), serious traffic violations, RR-grade-crossing violations, imminent-hazard out-of-service, or Clearinghouse positive-test prohibited status. Also use when planning a return-to-duty pathway, SAP process, or reinstatement timeline. Covers 49 CFR 383.51, Part 40 Subpart O, and Part 391.15.

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Use this skill when the user asks about International Fuel Tax Agreement (IFTA) compliance — quarterly returns, jurisdiction reporting, fuel + miles reconciliation, IFTA-100/101 forms, base jurisdiction selection, IFTA license + decals, recordkeeping requirements, common IFTA audit findings, or how to handle non-IFTA jurisdictions. Cite IFTA Articles of Agreement.

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Use when running analytical SQL over Parquet/CSV/JSON without a warehouse, replacing pandas for data wrangling, joining S3 data in-place, building local data marts, or embedding OLAP into an app. Triggers: read_parquet/read_csv setup, partitioned dataset queries, hive partitioning, glob patterns for S3, COPY TO export, attach Postgres/MySQL, UDFs in Python/R, MotherDuck cloud sync, columnar performance vs row stores. NOT for OLTP workloads (concurrent writes), distributed analytics at petabyte scale (use Spark/Trino), or vector search (use pgvector/Lance).

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Snowflake, BigQuery, clustering, partitioning, and materialized views for warehouse performance. Activate on: Snowflake, BigQuery, Redshift, query optimization, clustering, partitioning, materialized view, warehouse cost, query profile. NOT for: dbt model structure (use dbt-analytics-engineer), data modeling (use dimensional-modeler).

日本語の概要は準備中です。原文の説明を表示しています。

Build daemon/background processes that start on boot, run continuously, and manage their own lifecycle. Covers macOS launchd (plist files, agents vs daemons), Linux systemd (unit files), Windows services, process supervision, logging, health checks, graceful shutdown, auto-restart, and AI-powered daemons that manage LLM API connections and rate limits. Activate on: "daemon", "background process", "launchd", "systemd", "service file", "plist", "launch agent", "launch daemon", "auto-start", "always running", "process supervisor", "pm2", "background service", "boot service", "AI daemon", "long-running process". NOT for: container orchestration (use devops-automator), cron jobs that run and exit (use task-scheduler), web server deployment (use backend-architect).

日本語の概要は準備中です。原文の説明を表示しています。

Verify every visual-evidence artifact (screenshot/GIF/recording) attached to a PR carries a provenance manifest binding it to real daemon-backed truth — daemon port, run id, transcript head hash, agent node id, commit, and an honest real/fixture/mock source label — and that operator-control-panel PRs cover the required set of proof states. Use when gating a PR's proof artifacts before merge, auditing whether a "LIVE" visual claim is backed by a real daemon run versus a reused or fixture-backed mock, or defining the required state-coverage set for a control-panel change. NOT for the capture technique itself — headless Playwright, `screencapture -x -l`, non-interruptive capture (use port-daddy-agent-skill's visual-evidence doctrine), designing the receipt body schema an artifact attaches to (use agent-work-receipt-designer), or the broader dogfood/Potemkin product-quality bar (use multi-agent-authoring-product-bar).

日本語の概要は準備中です。原文の説明を表示しています。

Design discovery, directories, and guilds for agent swarms at scale. Use when agents need to find each other on a shared surface: capability indices, yellow-pages directories, whois/phonebook routing, reputation-aware discovery, and guild structures that scope trust. Covers the canonical prior art (FIPA Directory Facilitator, Contract Net, Chord/DHT, DNS-SD/Consul, EigenTrust, Greif's merchant guilds) and the failure modes (read-poverty, Sybil reset, Goodhart on rank, directory staleness, cold-start). Triggers: "agents can't find each other", "who owns this file/skill", "route a question to the right agent", "capability registry", "agent reputation", "guild / federation of fleets". NOT for issuing identities, granting authority, or automatically assigning work from a directory entry.

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Keeps a fiction story bible and checks text against it. Trigger to build, extend or extract (from a manuscript) a story, lore or world bible; to check chapters, game strings or generated drafts for contradictions or timeline breaks; to track a world timeline with branches and who is alive, or chart it; to brief a local model from canon; for naming rules; to share canon across repos; or say lorescribe (bible, manuscript, check, timeline, names, brief, audit). Research is researchscribe's; line edits commscribe's; real-data charts dataviz's; art pixelsmith's; audio soundsmith's; model runs lmstudiorunner's or comfyrunner's; no prose drafting.

日本語の概要は準備中です。原文の説明を表示しています。