Performs differential expression on bulk RNA-seq count data with DESeq2's negative-binomial GLM, Wald and LRT testing, apeglm/ashr/normal LFC shrinkage, independent filtering, Cook's outlier handling, VST/rlog transforms, and design formulas including paired, batch, and interaction terms. Use when running bulk DE, choosing DESeq2 over edgeR or limma-voom, building a paired or interaction design, applying LFC shrinkage for ranking or GSEA, choosing Wald vs LRT, troubleshooting padj=NA, picking VST vs rlog, importing salmon/kallisto via tximport, or analyzing prokaryotic RNA-seq.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Resolve subclonal copy number, whole-genome doubling, and copy-number tumor evolution from bulk sequencing with Battenberg, TITAN, and MEDICC2. Covers clonal versus subclonal copy-number states, haplotype phasing for subclonal resolution, cancer cell fraction, whole-genome-doubling detection and timing relative to mutations, mirrored subclonal allelic imbalance, and copy-number phylogenies. Use when a tumor is heterogeneous and bulk data shows non-integer copy number, when calling subclonal CNAs, detecting or timing whole-genome doubling, reconstructing copy-number evolution, or deciding between Battenberg and TITAN.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Use this skill when the user asks about hazardous materials (hazmat) transportation under 49 CFR 171-180 — placarding requirements, segregation tables, hazmat employee training (49 CFR 172 Subpart H), Hazmat Safety Permit (HMSP), shipping papers, packaging groups, emergency response phone, security plans, hazmat endorsement on CDL, and bulk vs non-bulk distinctions. Cite specific 49 CFR section.
日本語の概要は準備中です。原文の説明を表示しています。
x3allamerican/skills☆ 32026年5月17日 更新
Generates Bulkhead pattern for PHP 8.5. Creates resource isolation with semaphore-based concurrency limiting and thread pool isolation. Includes unit tests.
日本語の概要は準備中です。原文の説明を表示しています。
MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Audit and update metadata across multiple AEM Edge Delivery Services pages. Scans pages via the query index, identifies missing or inconsistent metadata (titles, descriptions, og tags, robots), and generates a corrected bulk metadata spreadsheet. Use when standardizing metadata across a site, preparing for launch, or fixing SEO issues at scale.
日本語の概要は準備中です。原文の説明を表示しています。
aemgdc/aemdev☆ 22026年10月13日 更新
Crawl websites and extract content from multiple pages via the Tavily CLI. Use this skill when the user wants to crawl a site, download documentation, extract an entire docs section, bulk-extract pages, save a site as local markdown files, or says "crawl", "get all the pages", "download the docs", "extract everything under /docs", "bulk extract", or needs content from many pages on the same domain. Supports depth/breadth control, path filtering, semantic instructions, and saving each page as a local markdown file.
日本語の概要は準備中です。原文の説明を表示しています。
Scoheart/agentskills☆ 22026年8月4日 更新
鍛えたい筋肉や器具に合う運動を探し、食品の栄養成分を調べるスキル。消費カロリーや体脂肪率の推定、減量・増量に向けた栄養配分にも使えます。
- 使える器具に合う運動を探したいとき
- 食品のカロリーやタンパク質の確認
- 減量・増量に向けた栄養配分
NousResearch/hermes-agent☆ 25.3万2026年10月13日 更新
Open Orbit briefing skill — selected by the Orbit pipeline when Gmail is the user's only connected connector, or when the user explicitly scopes their daily digest to Gmail. Pulls the past 24 hours of inbox activity (replies awaited, mentions, cc, auto- categorized bulk) from the user's authenticated Gmail connection and renders the digest as the Orbit Daily Digest email opened inside Gmail's reading view. This skill should not be triggered manually — it is invoked by Orbit's daily-digest scheduler against live Gmail data.
日本語の概要は準備中です。原文の説明を表示しています。
nexu-io/open-design☆ 10.1万2026年10月13日 更新
When the user wants help with paid advertising campaigns on Google Ads, Meta (Facebook/Instagram), LinkedIn, Twitter/X, or other ad platforms. Also use when the user mentions 'PPC,' 'paid media,' 'ROAS,' 'CPA,' 'ad campaign,' 'retargeting,' 'audience targeting,' 'Google Ads,' 'Facebook ads,' 'LinkedIn ads,' 'ad budget,' 'cost per click,' 'ad spend,' 'should I run ads,' 'ABM,' 'account-based marketing,' 'B2B ads,' 'lead quality,' 'negative keywords,' 'Performance Max,' 'thought leader ads,' 'when should I kill an ad,' 'search terms report,' 'wasted spend,' or 'is this campaign working.' Use this for campaign strategy, audience targeting, bidding, and optimization. For bulk ad creative generation and iteration, see ad-creative. For landing page optimization, see cro. For outbound to target accounts, see cold-email.
日本語の概要は準備中です。原文の説明を表示しています。
coreyhaines31/marketingskills☆ 5.5万2026年10月9日 更新
When the user wants to generate, iterate, or scale ad creative — headlines, descriptions, primary text, or full ad variations — for any paid advertising platform. Also use when the user mentions 'ad copy variations,' 'ad creative,' 'generate headlines,' 'RSA headlines,' 'bulk ad copy,' 'ad iterations,' 'creative testing,' 'write me some ads,' 'Facebook ad copy,' 'Google ad headlines,' 'LinkedIn ad text,' 'static ads,' 'ad templates,' 'iMessage ad,' 'chat reveal ad,' 'ChatGPT ad,' 'Apple Notes ad,' 'AirDrop ad,' 'creative strategy,' 'creative roadmap,' 'creative retro,' 'hook writing,' 'creative review page,' 'present ad creative for approval,' 'motion video ad,' 'faceless video ad,' 'UGC ad,' 'greenscreen ad,' 'TikTok/Reels ad format,' 'which ad format to make,' 'Meta ad format tier list,' or 'creative format taxonomy.' Use it to produce or iterate ad copy at scale. Copy avoids AI tells like 'it's not X, it's Y' reveals. For campaign strategy and targeting, see ads. For landing page copy, see copywriting.
日本語の概要は準備中です。原文の説明を表示しています。
coreyhaines31/marketingskills☆ 5.5万2026年10月9日 更新
Performs bulk RNA-seq differential expression analysis with PyDESeq2, including count validation, formula designs, explicit contrasts, Wald tests, FDR correction, coefficient-matched LFC shrinkage, and result visualization. Use for PyDESeq2 or Python DESeq2 workflows with biological replicates.
日本語の概要は準備中です。原文の説明を表示しています。
K-Dense-AI/scientific-agent-skills☆ 4.9万2026年10月12日 更新
Performs Scanpy single-cell RNA-seq QC, normalization, HVG selection, PCA/UMAP/t-SNE, clustering, exploratory marker ranking, pseudobulk preparation, visualization, and Seurat or SingleCellExperiment RDS conversion to h5ad. Applies to established exploratory scRNA-seq workflows with explicit count and expression provenance; complementary skills cover scvi-tools models and AnnData format details.
日本語の概要は準備中です。原文の説明を表示しています。
K-Dense-AI/scientific-agent-skills☆ 4.9万2026年10月12日 更新
Infers candidate gene regulatory networks from bulk or single-cell expression data using AertsLab Arboreto GRNBoost2 and GENIE3. Use for transcription factor-target association ranking, compatible Dask execution, sparse expression inputs, and network stability checks.
日本語の概要は準備中です。原文の説明を表示しています。
K-Dense-AI/scientific-agent-skills☆ 4.9万2026年10月12日 更新
Azure Cosmos DB JavaScript/TypeScript SDK (@azure/cosmos) for data plane operations. Use for CRUD operations on documents, queries, bulk operations, and container management.
日本語の概要は準備中です。原文の説明を表示しています。
sickn33/agentic-awesome-skills☆ 4.8万2026年10月8日 更新
Send SMS messages with Azure Communication Services SMS Java SDK. Use when implementing SMS notifications, alerts, OTP delivery, bulk messaging, or delivery reports.
日本語の概要は準備中です。原文の説明を表示しています。
sickn33/agentic-awesome-skills☆ 4.8万2026年10月13日 更新
Manage Sub2API admin APIs for accounts, redeem codes, groups, proxies, error passthrough rules, TLS fingerprint profiles, imports, exports, batch updates, and raw administrator API calls. Use when the user mentions Sub2API, admin API keys, account management, redeem code management, recharge codes, invitation codes, bulk account import/export, keeping or deleting accounts, refreshing accounts, clearing errors, CRS sync, or managing Sub2API backend settings through the admin API.
日本語の概要は準備中です。原文の説明を表示しています。
Wei-Shaw/sub2api☆ 4.4万2026年10月13日 更新
Read, create, or edit Excel spreadsheets (.xlsx/.xlsm) — sheet data, formulas, styles, charts, multi-sheet workbooks — and bulk .csv/.tsv tables; use whenever a spreadsheet is the input or the deliverable (extract/analyze data, add columns/formulas/formatting/charts, clean messy tables, build from scratch), but not for Google Sheets API or Word/PDF/script outputs.
日本語の概要は準備中です。原文の説明を表示しています。
HKUDS/DeepTutor☆ 4.1万2026年10月13日 更新
Bulk-migrate metadata to GitHub issue fields from two sources: repo labels (e.g. priority labels to a Priority field) and Project V2 fields. Use when users say "migrate my labels to issue fields", "migrate project fields to issue fields", "convert labels to issue fields", "copy project field values to issue fields", or ask about adopting issue fields. Issue fields are org-level typed metadata (single select, text, number, date) that replace label-based workarounds with structured, searchable, cross-repo fields.
日本語の概要は準備中です。原文の説明を表示しています。
github/awesome-copilot☆ 4万2026年10月12日 更新
Generate Python SDK setup + CRUD + bulk + paging snippets using official patterns.
日本語の概要は準備中です。原文の説明を表示しています。
github/awesome-copilot☆ 4万2026年10月12日 更新
Creates and manages annotation configs (categorical, continuous, freeform label schemas) and annotation queues (human review workflows) on Arize. Applies human annotations to project spans via the Python SDK. Use when the user mentions annotation config, annotation queue, label schema, human feedback, bulk annotate spans, update_annotations, labeling queue, annotate record, or human review.
日本語の概要は準備中です。原文の説明を表示しています。
github/awesome-copilot☆ 4万2026年10月12日 更新
Detecting data exfiltration attempts from AWS S3 buckets by analyzing CloudTrail S3 data events, VPC Flow Logs, GuardDuty findings, Amazon Macie alerts, and S3 access patterns to identify unauthorized bulk downloads and cross-account data transfers.
日本語の概要は準備中です。原文の説明を表示しています。
mukul975/Anthropic-Cybersecurity-Skills☆ 3.4万2026年8月31日 更新
Automates the enrichment of raw indicators of compromise with multi-source threat intelligence context using SOAR platforms, Python pipelines, or TIP playbooks to reduce analyst triage time and standardize enrichment outputs. Use when building automated enrichment workflows integrated with SIEM alerts, email submission pipelines, or bulk IOC processing from threat feeds. Activates for requests involving SOAR enrichment, Cortex XSOAR, Splunk SOAR, TheHive, Python enrichment pipelines, or automated IOC processing.
日本語の概要は準備中です。原文の説明を表示しています。
mukul975/Anthropic-Cybersecurity-Skills☆ 3.4万2026年8月31日 更新