3,976 件 ・ 関連度順
概要と使いどころ
Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods. Identify CTCF-mediated loops and enhancer-promoter contacts. Use when detecting chromatin loops from Hi-C data.
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Identify tumor neoantigens from somatic mutations using pVACtools for personalized cancer immunotherapy. Predict mutant peptides that bind patient HLA and may elicit T-cell responses. Use when identifying vaccine targets or checkpoint inhibitor response biomarkers from tumor sequencing data.
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Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
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Predicts ADMET properties using ADMETlab 3.0 API or DeepChem models. Estimates bioavailability, CYP inhibition, hERG liability, and 119 toxicity endpoints with uncertainty quantification. Filters for PAINS and other structural alerts. Use when filtering compounds for drug-likeness or prioritizing leads by predicted safety.
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Screen S&P 500 stocks for Mark Minervini's Volatility Contraction Pattern (VCP) and detect historical VCPs in a single ticker's price path. Identifies Stage 2 uptrend stocks forming tight bases with contracting volatility near breakout pivot points; in historical single-ticker mode walks a multi-year history and emits every VCP that formed with forward-outcome stats (breakout / stop-hit / timeout). Use when user requests VCP screening, Minervini-style setups, tight base patterns, volatility contraction breakout candidates, Stage 2 momentum stock scanning, or historical VCP pattern study on a specific ticker (e.g. FIX, TSLA).
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Consensus planning entrypoint that auto-gates vague ultragoal requests before execution
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Memory integrity audit. Detects hallucinations, circular confirmations, and state poisoning. Runs automatically after 2 consecutive failures or at nightly deep dive. Uses Opus 4.6 as the auditor model.
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Rebuild slide images, scanned or image-based PPT/PPTX files, and PDF decks into object-level editable PowerPoint (.pptx), preserving speaker notes when supplied. Use for making visual slides editable or reconstructing slides from screenshots; not for authoring new presentations from scratch.
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Use when the user asks to "author our durable brand message hierarchy", "build the brand message house that seeds the canon", or "define the main narrative, three pillars, and tagline for the whole brand"; produces the DURABLE brand message system — main narrative, three value pillars, per-persona proof points (each labeled Measured / User-provided / '[needs source]'), and the tagline/one-liner — that seeds the narrative-registry canon and from which every per-launch house derives. Not for a single launch's message house or PR-FAQ — use message-house-builder; not for claim adjudication — use offer-claims-registry; not for the change-narrative arc itself — use strategic-narrative-designer. 品牌消息屋/主叙事/三支柱/标语/持久叙事 canon
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Use when the user asks to "map what our surfaces say today", "inventory our current messaging", or "find the gap between what we say and what we mean"; produces the narrative baseline — a surface-by-surface inventory of what every owned touchpoint (homepage, pricing, docs, decks, social bios, email footers) claims RIGHT NOW, each line labeled Measured / User-provided / Estimated, plus a per-surface gap read vs the intended message and the drift-baseline snapshot the Evaluate phase measures future drift against. Not for authoring the canon — use message-system-architect; not for scoring the surfaces or running the vetoes — use narrative-quality-auditor. 现状叙事盘点/各触点口径/意图差距/漂移基线
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Use when the user asks to "map the category narrative", "tear down how competitors tell their story", or "find the language conventions in our market"; produces a category narrative map — the dominant stories and points of view in the category, its language conventions and framing clichés, and a per-competitor narrative teardown (arc, claimed onlyness, proof pattern) plus how each rival's messaging has shifted over time (scraped copy vs archived copy). Not for the positioning canvas itself — use positioning-mapper; not for the beachhead's beliefs and objections — use audience-belief-mapper; not for SERP keyword targeting — use keyword-research; not for claim adjudication — use offer-claims-registry. 品类叙事/竞争叙事拆解/语言惯例/叙事演变
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Use when the user asks to "build a message house", "write a PR-FAQ for our launch", or "define the launch narrative and value pillars"; derives from the positioning canvas a message house — tagline, one-liner, three value pillars, per-persona proof points (each labeled Measured / User-provided / [needs source]) — plus a working-backwards PR-FAQ narrative spine (launch-day tense, empty-chair test, five external + five internal FAQs) and per-channel message angle packs (angles, not finished copy). Not for the positioning canvas itself — use positioning-mapper; not for finished blog posts or pages — use content-writer; not for ad or email units — use each discipline creative builder; not for claim adjudication — use offer-claims-registry. 消息屋/PR-FAQ/价值支柱/发布叙事
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Use when the user asks to "codify our brand voice", "define naming rules for our products and tiers", or "write the tone-of-voice guide with banned phrases"; produces the brand-level voice canon (register, tone spectrum, banned-phrase list, few-shot examples drawn only from the brand's own published material) and the naming tax (product / feature / tier naming rules plus approved and banned terms) that seeds the narrative-registry canon and that every channel's voice adaptation points up to. Not for per-platform voice adaptation — use channel-registry's voice-dossier; not for finished copy or blog posts — use content-writer; not for the message hierarchy itself — use message-system-architect; not for claim adjudication — use offer-claims-registry. 品牌语气/词汇表/命名税/禁用词/品牌语言规范
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Use when the user asks to "run a deliverability pre-flight before I send", "check my SPF/DKIM/DMARC/BIMI", "why am I landing in spam / promotions", or "score my sender reputation and list hygiene"; runs the ONE-TIME pre-send SEND S1 authentication pre-flight and builds the SEND S (Sender-integrity / Deliverability) evidence read — DNS + DMARC-RUA auth, domain/IP reputation, inbox placement, content/link/render, and point-in-time bounce/complaint hygiene — using Pass/Partial/Fail/Unknown/N/A states and scoring only at complete applicable coverage. Not for the recurring hygiene trend — use list-hygiene-monitor; not for final EQS or veto verdicts — use email-quality-auditor; not for segments/suppression lists — use list-segment-builder. 邮件送达率预检/SPF DKIM DMARC认证/发件域声誉
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Use when platform-reported conversions disagree with GA4/ecommerce, when you suspect Meta and Google are double-counting the same sales, or for a standing (monthly) reconciliation workbook that de-dups stacked credit against an order-ID truth set, normalizes attribution windows and currency, compares attribution models, and reads incrementality from a geo/holdout test. Not for the point-in-time R2 veto or RQS gate — use ad-account-auditor; not for the ROI/ROAS ratio math itself — use roi-calculator; not for organic dark-social share attribution or GA4 direct-traffic decomposition — use dark-social-attributor. 付费广告归因对账/去重/增量
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Critique a rendered screen's hierarchy — entry point, eye flow, weight distribution, and emphasis. Use when attention lands in the wrong place. For establishing hierarchy in new work, use `visual-hierarchy` (ui-design).
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Map the full ecosystem of touchpoints, channels, and relationships across a service. Use when the experience spans more than one product. For one persona's linear journey use `journey-map` (design-research); for backstage operations use `service-blueprint`.
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Set line length and measure for comfortable reading across type sizes and breakpoints. Use when tuning body text. Covers measure only — for the full size and weight scale, use `typography-scale`.
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Diagram screen-level paths, decision points, and branch logic. Use when specifying how a feature is traversed. For the emotional end-to-end arc, use `journey-map` (design-research).
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Define a responsive grid — columns, gutters, margins, and breakpoint behaviour. Use when establishing page structure. For the spacing scale inside components use `spacing-system`; for cross-device behaviour use `responsive-design`.
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Design to iOS and Android conventions — what each OS mandates, where they diverge, and when to unify. Use when shipping native apps. For breakpoint adaptation use `responsive-design`; for matching competitor patterns use `jakobs-law` (interaction-design).
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Reconcile what the numbers say with what users say, and design the study that settles it rather than restates it. Use when behavioural data and research findings point different ways. For reading the data on its own, use `behavioural-analytics`; for synthesising interviews on their own, use `affinity-diagram`.
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Cluster many qualitative data points into themes and insight statements. Use when synthesising across multiple sessions or sources. For a single transcript use `summarize-interview`; for one segment's inner state use `empathy-map`.
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Establish review gates — criteria, checkpoints, and approval flow. Use when work ships without consistent review. For running one individual session, use `design-critique`.
日本語の概要は準備中です。原文の説明を表示しています。