412 件 ・ 関連度順
概要と使いどころ
You are a PR optimization expert specializing in creating high-quality pull requests that facilitate efficient code reviews. Generate comprehensive PR descriptions, automate review processes, and ensure PRs follow best practices for clarity, size, and reviewability.
日本語の概要は準備中です。原文の説明を表示しています。
AI DevKit · Analyze and simplify existing implementations to reduce complexity, improve maintainability, and enhance scalability. Use when users ask to simplify code, reduce complexity, refactor for readability, clean up implementations, improve maintainability, reduce technical debt, or make code easier to understand.
日本語の概要は準備中です。原文の説明を表示しています。
Two pipelines ending at a scanner-look PDF. (1) Phone photos of paper documents (contracts, stamped certificates, receipts, forms, handwritten notes) → clean scanner-quality PDF: perspective rectification + noteshrink whitening + A4 assembly + mandatory whole-document check. Trigger: "把照片 做成扫描件", "photos to scanned PDF", "make this look scanned", "手机拍的 文档转 PDF", "盖章文件扫描", replacing pages in an existing scanned PDF, any CamScanner-like request. (2) A digital document with no signature yet (rendered docx/PDF, confirmation form, contract draft) → make it look hand-signed and scanned: synthesize a handwriting-style signature, composite it onto the signature line, apply the same scan-look post-processing. Trigger: "帮我做个手写签名", "生成签名盖到这份文件上", "做成签过字的扫描件", "synthesize a signature", any request for a document that needs to look signed without a real photographed signature. Do NOT hand-roll levels/contrast enhancement for scan-look — tried and rejected twice; this skill's pipeline is the proven one.
日本語の概要は準備中です。原文の説明を表示しています。
EMC pre-compliance risk analysis for KiCad PCB designs — 18 check categories, 44 rule IDs covering ground planes, decoupling, I/O filtering, switching harmonics, clock routing, differential pair skew, board edge radiation, PDN impedance, return paths, crosstalk, ESD protection, shielding, and magnetic leakage from switching inductors. Produces severity-ranked risk report with pre-compliance test plan. Supports FCC Part 15, CISPR 32, CISPR 25 (automotive), MIL-STD-461G. SPICE-enhanced when available. Use when the user asks about EMC, EMI, radiated/conducted emissions, FCC compliance, CE marking, CISPR, ground plane issues, decoupling strategy, clock routing EMC, switching noise, differential pair skew, or whether their board will pass EMC testing. Also for "will this pass FCC?", "check my EMC", "is my ground plane okay?", "check my decoupling", or "generate an EMC test plan".
日本語の概要は準備中です。原文の説明を表示しています。
EMC pre-compliance risk analysis for KiCad PCB designs — 18 check categories, 44 rule IDs covering ground planes, decoupling, I/O filtering, switching harmonics, clock routing, differential pair skew, board edge radiation, PDN impedance, return paths, crosstalk, ESD protection, shielding, and magnetic leakage from switching inductors. Produces severity-ranked risk report with pre-compliance test plan. Supports FCC Part 15, CISPR 32, CISPR 25 (automotive), MIL-STD-461G. SPICE-enhanced when available. Use when the user asks about EMC, EMI, radiated/conducted emissions, FCC compliance, CE marking, CISPR, ground plane issues, decoupling strategy, clock routing EMC, switching noise, differential pair skew, or whether their board will pass EMC testing. Also for "will this pass FCC?", "check my EMC", "is my ground plane okay?", "check my decoupling", or "generate an EMC test plan".
日本語の概要は準備中です。原文の説明を表示しています。
Capture durable session learnings, stage for human promotion to 05-knowledge/lizard, and propose skill/CLAUDE.md patches. Triggered by /harvest, SessionEnd hook staging, or nightly enhance. Never writes durable knowledge without your approval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates an x-ray.md pre-audit report covering overview, enhanced threat model (protocol-type profiling, git-weighted attack surfaces, temporal risk analysis, composability dependency mapping), invariants, integrations, docs quality, test analysis, and developer/git history. Triggers on 'x-ray', 'audit readiness', 'readiness report', 'pre-audit report', 'prep this protocol', 'protocol prep', 'summarize this protocol'.
日本語の概要は準備中です。原文の説明を表示しています。
Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model. Covers bedtools fisher (analytic 2x2 screen), bedtools shuffle + jaccard permutation, GAT (isochore/GC-conditioned simulation with FDR), regioneR (flexible permutation, randomizeRegions vs circularRandomizeRegions, localZScore), LOLA (universe-relative Fisher against a region database), and GREAT/rGREAT (regulatory-domain binomial + hypergeometric for ontology-from-regions). Stresses the universe/background choice, matched background, blacklist exclusion, and multiple-testing control. Use when asking whether peaks/regions are enriched at enhancers/TFBS/features, scoring region-set colocalization or region-set enrichment, comparing CNV/SV concordance, or turning an overlap count into a defensible p-value.
日本語の概要は準備中です。原文の説明を表示しています。
Performs proximity operations on genomic intervals with bedtools (closest, window, flank, slop) and pybedtools - nearest-feature queries with signed/strand-aware distance, fixed-radius window searches, strand-aware promoter construction, and interval extension. Covers the closest -d/-D a/b/ref/-t/-k/-io/-iu/-id flags, the -D ref strand sign-flip, silent chromosome-end clipping in slop/flank, -t all tie double-counting, and the critical distinction between a geometry answer (nearest TSS) and a biology answer (which gene an element regulates). Use when assigning peaks or variants to genes, defining promoters from a gene model, building distance-to-TSS distributions, finding features within a window, or extending intervals - and when deciding whether nearest-gene is a fair prior (GWAS locus) or a trap (distal enhancer).
日本語の概要は準備中です。原文の説明を表示しています。
Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity scoring. Covers the motif-pruning-as-directionality principle, regulon specificity scoring, run-to-run stability, and database/species matching. Use when identifying TF regulons, scoring TF activity per cell, finding master regulators of cell identity, or comparing regulon activity across conditions. For enhancer-driven multiomic GRNs see multiomics-grn; for bulk inference and VIPER protein-activity see grn-inference.
日本語の概要は準備中です。原文の説明を表示しています。
Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation conventions. Covers EnhancedVolcano, ggplot2, matplotlib, and the apeglm/ashr/normal shrinkage decision. Use when visualizing differential-expression results (RNA-seq, ChIP-seq, ATAC-seq, proteomics) or any per-feature effect-size + p-value table.
日本語の概要は準備中です。原文の説明を表示しています。
Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Nat Commun 12:1302), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.
日本語の概要は準備中です。原文の説明を表示しています。
Generates 3D conformer ensembles using RDKit ETKDGv3 with knowledge-enhanced distance geometry, MMFF94/UFF force-field optimization, CREST + GFN2-xTB semi-empirical refinement, and macrocycle-aware torsion preferences. Provides explicit decision rules for single vs ensemble conformer use, RMSD pruning, energy windows, conformer count, and force-field choice. Use when preparing 3D ligands for docking, generating descriptor input for 3D QSAR, or sampling macrocycle/peptide conformational ensembles.
日本語の概要は準備中です。原文の説明を表示しています。
Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda scheduling, soft-core potentials, MBAR/BAR analysis, cycle-closure validation, and protocol-appropriate enhanced sampling. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.
日本語の概要は準備中です。原文の説明を表示しています。
Map nucleosome center positions, occupancy, and fuzziness from ATAC-seq fragment-size patterns using NucleoATAC, ATACseqQC, DANPOS3, or scprinter. Use when characterizing nucleosome organization at promoters and enhancers, calling +1/-1 nucleosomes flanking NFRs, generating V-plots for chromatin structure visualization, or comparing nucleosome positioning between conditions.
日本語の概要は準備中です。原文の説明を表示しています。
Read, write, and manipulate medical imaging data (DICOM, NIfTI, NRRD) in MATLAB. Covers Image Processing Toolbox functions (dicomreadVolume, niftiread, dicomContours, dicomanon) and Medical Imaging Toolbox enhanced APIs (medicalVolume, medicalImage, medicalref3d, extractSlice, updateOrientation). Use when reading medical files, listing DICOM series, extracting spatial referencing, changing orientation, working with RT structures, or anonymizing DICOM data. Some features require Medical Imaging Toolbox — see skill body and references for details.
日本語の概要は準備中です。原文の説明を表示しています。
Format reference for Power BI Enhanced Report (PBIR) JSON schemas and patterns. Automatically invoke when the user asks about PBIR JSON structure, visual.json properties, PBIR expressions, objects vs visualContainerObjects, theme inheritance, conditional formatting patterns, extension measures, bookmarks, field references, filter formatting, query roles, PBIR page structure, report wallpaper, or any PBIR metadata format question.
日本語の概要は準備中です。原文の説明を表示しています。
When the user wants to analyze Google Search Console data, use the GSC API, or interpret search performance. Also use when the user mentions "GSC," "Search Console," "indexing report," "Core Web Vitals," "Enhancements," "Insights report," "search performance," "search queries," "search performance report," "URL inspection," "impressions," "CTR," "average position," "index coverage," "GSC data analysis," "Search Console API," or "searchanalytics.query." When the user wants to rewrite title tags (not only report on them), use title-tag. For meta description rewrites, use meta-description.
日本語の概要は準備中です。原文の説明を表示しています。
Use when building or debugging UE5 gameplay: a character with double jump or dash, abilities with cooldowns, enemy AI that patrols, chases and attacks, a health bar or HUD; choosing Blueprint vs C++, GAS or not, StateTree vs Behavior Tree, EQS or Mass; setting up Enhanced Input, Common UI or UMG; replication, RepNotify, save games, World Partition state; "Blueprints are slow", Tick, casts and hard references; "ability won't activate", "enemy ignores the player"; or writing automated gameplay tests with injected input.
日本語の概要は準備中です。原文の説明を表示しています。
Use when editing an existing image on Scenario through MCP with a tool model, not a new generation: upscale or enhance to 2x, 4K, 8K, super resolution, 3D LUT color grade, color correction, posterize, solarize, vignette, film grain, blur, sharpen, glow, chromatic aberration, oilify, cubism, crystallize, dodge and burn, tint, desaturate, expand or uncrop, reframe an aspect ratio, resize to exact pixels, slice tiles, contact sheet, split into layers, remove a background or watermark, vectorize.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze images, video, speech, motion, products, and websites; route local vision, audio, depth, tracking, matting, identity, and restoration models; auto-edit, replicate, enhance, caption, voice, assemble, annotate, validate, and export editable Timeline Studio projects and videos. Use for reference-video remakes, filter and repeated-shot reconstruction, subject-aware reframing, clip splitting, source-time speed curves, Color Wheels grading, ramps and holds, person or product cutout, person or object outline, authorized face swap, shot and timing reconstruction, timeline markers, chapters, beat cues, review notes and ranges, supplied or web-sourced footage, AI video platform selection, cleanup, highlights, product promotion, website walkthroughs, image-to-video assisted edits, optical-flow editing, depth-assisted relighting, grayscale depth-video conversion, depth/2.5D/transition finishing, AI voiceover, subtitles, short-form production, .timeline automation, or editor evaluation.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze prompts for clarity, structure, examples, and output reliability
日本語の概要は準備中です。原文の説明を表示しています。
Claude Code agent generation system that creates custom agents and sub-agents with enhanced YAML frontmatter, tool access patterns, and MCP integration support following proven production patterns
日本語の概要は準備中です。原文の説明を表示しています。