Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
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Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
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Perform geometric calculations on protein structures using Biopython Bio.PDB. Use when measuring distances, angles, and dihedrals, superimposing structures, calculating RMSD, or computing solvent accessible surface area (SASA).
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Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extracting sequences from PDB files.
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Read and manipulate Flow Cytometry Standard (FCS) files. Covers loading data, accessing parameters, and basic data exploration. Use when loading and inspecting flow or mass cytometry data before preprocessing.
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Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different formats. Use when loading or converting Hi-C contact matrices.
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Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
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Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
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Call accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when identifying open chromatin regions from aligned ATAC-seq BAM files, different from ChIP-seq peak calling.
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Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS. Use when identifying TF occupancy patterns within accessible regions, as TF binding protects DNA from Tn5 cutting.
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Fetch dependency source code to give AI agents deeper implementation context. Use when the agent needs to understand how a library works internally, read source code for a package, fetch implementation details for a dependency, or explore how an npm/PyPI/crates.io package is built. Triggers include "fetch source for", "read the source of", "how does X work internally", "get the implementation of", "opensrc path", or any task requiring access to dependency source code beyond types and docs.
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Use when the user asks to "pick which social channels to run", "should we be on X platform or 小红书", or "plan our organic social channel portfolio"; produces an audience/objective-first portfolio with capability/access matrix, cadence-budget reality check, declared ECHO operating profile, boundary routing, and proposed-state registry events. Not for recording canonical channel facts — use channel-registry. 社媒渠道选择/渠道组合规划/平台能力矩阵/自然社媒
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Use when the user asks to "build the email HTML", "make this email responsive", "fix dark-mode rendering", or "QA the email across clients"; produces the coded HTML build — a responsive table layout, dark-mode + accessibility pass, a client-render matrix, image-block fallbacks, and a plain-text parity check. Not for writing the copy — use email-creative-builder; not for scoring the email or computing EQS — use email-quality-auditor. 邮件HTML/响应式邮件/暗色模式渲染
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Builds the backend of an app clone: auth, database migrations and access rules, payments with Stripe, email, background jobs and third-party integrations through official APIs only, plus a security checklist. Use when the user says "add login", "set up auth", "wire up the database", "add payments", "connect Stripe", "add Google Calendar", "send emails", "backend for my clone", or when /replica-build is running on fake data.
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Plans the stack, database schema and API for an app clone, from the recon map replica-recon wrote. Picks boring, managed tech, turns the inferred data model into real SQL with indexes and access rules, lists every route by flow, and orders the build as a thin vertical slice first. Use when the user says "plan the clone", "what stack should I use", "design the database", "write the schema", "plan the API", "architecture for my version of X", or after /replica-recon finishes.
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Run an evidence-led web quality audit covering performance, accessibility, SEO, best practices, and agentic browsing. Use when asked to "audit my site", "review web quality", "run lighthouse audit", "check page quality", or "optimize my website".
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Critique a rendered screen's colour — contrast ratios, palette coherence, and semantic meaning. Use when reviewing one screen. For a product-wide WCAG audit use `accessibility-audit` (design-systems); for building the palette use `color-system` (ui-design).
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Select chart types and design data encodings — marks, axes, labels, and accessible chart styling. Use when presenting data graphically. Owns chart selection and encoding only; the categorical colour ramp itself belongs to `color-system`.
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Inventory and prioritise accumulated design inconsistencies across a product. Use when drift has built up over time. For token coverage specifically use `design-token-audit` (designer-toolkit); for WCAG gaps use `accessibility-audit` (design-systems).
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Specify one component — props, states, variants, accessibility, and usage rules. Use when defining a library component. For the reusable doc scaffold use `documentation-template`; for a problem-solution pattern use `pattern-library`.
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Guides Amazon SES onboarding for domain-based email sending. Covers identity configuration, production access, an optional first test send, and troubleshooting setup, authentication, or sending failures. Use when setting up SES, resuming incomplete onboarding, or leaving the sandbox. Does not cover inbound email or Mail Manager, SMS/voice, WhatsApp, SNS, Pinpoint, or WorkMail.
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Create and secure S3 buckets following AWS best practices for access control, encryption, monitoring, and remediation of misconfigurations. Use when the user wants to secure a new bucket, audit an existing bucket, fix a security finding, configure encryption, or enable logging and monitoring. Do NOT use for general S3 data operations, S3 Tables setup, or discovering existing data assets.
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Use when connecting your agent to external APIs, tools, or services via Gateway, or restricting tool access with Cedar policies. Handles gateway setup, target types, outbound auth (OAuth, API key, IAM), credentials, and Cedar policy authoring. Triggers on: "connect to API", "add gateway", "connect to MCP server", "Lambda tools", "OpenAPI", "gateway target", "Cedar policy", "restrict tools", "policy engine", "gateway auth error", "store API key", "outbound credential", "env var API key", "API key None after deploy", "credential not available after deploy", "should this be a gateway target", "give my agent tools", "add tools to agent". Not for inbound auth (who can call your agent) — use agents-harden. Not for debugging agent behavior — use agents-debug. Not for VPC networking errors (agent can't reach APIs due to VPC) — use agents-build. Not for creating or hosting a new MCP server project — use agents-get-started.
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Use when your agent or environment is broken — wrong answers, errors, timeouts, tool failures, or CLI issues. Reads traces and logs to diagnose root causes. Also checks prerequisites when the CLI itself isn't working. Triggers on: "agent not working", "wrong answer", "agent error", "tool call failing", "debug agent", "check logs", "read traces", "broken", "500 error", "424 error", "model access denied", "command not found", "stuck in DELETING", "maxVms exceeded", "cold start diagnosis", "cold start slow", "agentcore create error", "create failed", "exit code 7", "connection refused local dev". Not for deploy failures — use agents-deploy. Not for performance tuning without errors — use agents-optimize. Not for VPC configuration — use agents-build. Not for observability setup or missing logs — use agents-optimize.
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Diagnoses and resolves Amazon S3 Files issues including mount failures, permission errors, synchronization problems, and performance issues. Use when the user has an S3 file system that is not mounting, returning access denied, not syncing changes to S3, showing files in lost+found, or performing slower than expected.
日本語の概要は準備中です。原文の説明を表示しています。